Psoriasis and comorbidities: general practitioners’ awareness

INTRODUCTION: Systemic inflammatory diseases such as psoriasis, systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA) are associated with an increased prevalence of cardiovascular diseases (CVD) and other comorbidities. The primary aim of this study was to assess the screening practices of general practitioners (GPs) with regard to the most frequent comorbidities in patients with psoriasis. METHODS: We adapted, with permission, a questionnaire that was used by Parsi et al. in 2012, which was then distributed to GP residents and consultants. RESULTS: Overall, 372 questionnaires were collected. Significantly more physicians screen for CV risk factors in patients with RA and SLE than in patients with psoriasis. There was no statistically significant difference between GP residents in the initial and final phase of residency, or between GP residents and consultants regarding awareness of increased prevalence of CVD in psoriasis or comorbidity screening practices in psoriasis patients. CONCLUSIONS: Most GP residents and consultants that participated in this study are not aware of an increased CV risk in patients with psoriasis and assign greater importance regarding this risk to other inflammatory diseases such as RA and SLE.info:eu-repo/semantics/publishedVersio

Cowden syndrome: clinical case and a brief review

Cowden syndrome is a rare genodermatosis of autosomal dominant inheritance characterized by multiple hamartomas in several organs and an increased risk of malignancies. We present the case of a 53-year-old man with a history of benign and malignant thyroid disease, intestinal polyposis, and Chiari malformation. He had several trichilemmomas, papillomatosis of the oral cavity, macular pigmentation of the glans penis, among other clinical features suggestive of Cowden syndrome. Given the suspicion, genetic study was conducted and PTEN mutation was identified. Cowden syndrome affects 1:200,000 individuals. Mucocutaneous lesions are almost always present and there may be other typical features involving other organs, namely thyroid, colon, and brain. Mucocutaneous lesions may be the initial manifestation of this disorder and usually precede the onset of malignant lesions, making timely diagnosis essential for proper monitoring and screening

Cities and climate change: Barcelona, Lyon, Marseille, Montréal, Nantes, Rennes, Roma, Stuttgart, Toulouse, Wien / sous la direction de Jean-Jacques Terrin ; collaboration de Jean-Baptiste Marie

International audienceLe réchauffement global de la planète et les dérèglements météorologiques vont croître considérablement d’ici la fin du xxie siècle. La ville n’échappe pas à l’influence de ces changements climatiques qui engendrent des îlots de chaleur urbains — caractérisés par des hausses de température parfois importantes dans le centre par rapport à la périphérie et qui entraînent dysfonctionnements et inconfort. Ce phénomène est dû à l’accumulation d’un certain nombre de facteurs : la densité urbaine, la circulation automobile, la minéralisation excessive et le déficit de végétal et d’eau dans les espaces publics. Les métropoles tentent d’agir. Dans cet ouvrage, chercheurs, experts et responsables locaux des villes de Barcelone, Lyon, Marseille, Montréal, Nantes, Rennes, Rome, Stuttgart, Toulouse et Vienne analysent l’impact que peuvent avoir les formes architecturales et urbaines, les dispositifs paysagers, ainsi que le choix de matériaux et de technologies de construction sur la réduction des effets néfastes de ces îlots de chaleur