The development of two computerized study units: Demonstrating two instruction theories.

Using one Instruction Theory for each, two Computer-assisted Instruction programs were created to teach the topic of Small-group Meetings. The Gagne-Briggs theory and the inquiry theory of instruction were used for their usefulness to instruct in different situations: the Gagne-Briggs theory for classroom instruction, and the Inquiry theory for workplace-based training. To assist in creating both CAI programs, work by David Jonassen (1986) was used as a step-by-step outline for the creation of hypertexts. This outline was also used as a model for the linear Gagne-Briggs based program. Upon completion, each program was tested by student volunteers who examined the usefulness, overall cohesiveness, ease of use, understandability, and usefulness as an instructional project. It was expected that those who used the Gagne-Briggs based program would have a greater understanding of the general overall material, while those who used the Inquiry based program would have a better understanding of a few select areas. (Abstract shortened by UMI.)Dept. of Communication Studies. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1997 .W53. Source: Masters Abstracts International, Volume: 39-02, page: 0309. Adviser: Kai Hildebrandt. Thesis (M.A.)--University of Windsor (Canada), 1998

Efficient simulation scheme for a class of quantum optics experiments with non-negative Wigner representation

We provide a scheme for efficient simulation of a broad class of quantum optics experiments. Our efficient simulation extends the continuous variable Gottesman-Knill theorem to a large class of non-Gaussian mixed states, thereby identifying that these non-Gaussian states are not an enabling resource for exponential quantum speed-up. Our results also provide an operationally motivated interpretation of negativity as non-classicality. We apply our scheme to the case of noisy single-photon-added-thermal-states to show that this class admits states with positive Wigner function but negative P -function that are not useful resource states for quantum computation.Comment: 14 pages, 1 figur

A Neanderthal Sodium Channel Increases Pain Sensitivity in Present-Day Humans.

The sodium channel Nav1.7 is crucial for impulse generation and conduction in peripheral pain pathways [1]. In Neanderthals, the Nav1.7 protein carried three amino acid substitutions (M932L, V991L, and D1908G) relative to modern humans. We expressed Nav1.7 proteins carrying all combinations of these substitutions and studied their electrophysiological effects. Whereas the single amino acid substitutions do not affect the function of the ion channel, the full Neanderthal variant carrying all three substitutions, as well as the combination of V991L with D1908G, shows reduced inactivation, suggesting that peripheral nerves were more sensitive to painful stimuli in Neanderthals than in modern humans. We show that, due to gene flow from Neanderthals, the three Neanderthal substitutions are found in ∼0.4% of present-day Britons, where they are associated with heightened pain sensitivity

Negative Quasi-Probability as a Resource for Quantum Computation

A central problem in quantum information is to determine the minimal physical resources that are required for quantum computational speedup and, in particular, for fault-tolerant quantum computation. We establish a remarkable connection between the potential for quantum speed-up and the onset of negative values in a distinguished quasi-probability representation, a discrete analog of the Wigner function for quantum systems of odd dimension. This connection allows us to resolve an open question on the existence of bound states for magic-state distillation: we prove that there exist mixed states outside the convex hull of stabilizer states that cannot be distilled to non-stabilizer target states using stabilizer operations. We also provide an efficient simulation protocol for Clifford circuits that extends to a large class of mixed states, including bound universal states.Comment: 15 pages v4: This is a major revision. In particular, we have added a new section detailing an explicit extension of the Gottesman-Knill simulation protocol to deal with positively represented states and measurement (even when these are non-stabilizer). This paper also includes significant elaboration on the two main results of the previous versio

Loss of Olfactory Receptor Genes Coincides with the Acquisition of Full Trichromatic Vision in Primates

Olfactory receptor (OR) genes constitute the molecular basis for the sense of smell and are encoded by the largest gene family in mammalian genomes. Previous studies suggested that the proportion of pseudogenes in the OR gene family is significantly larger in humans than in other apes and significantly larger in apes than in the mouse. To investigate the process of degeneration of the olfactory repertoire in primates, we estimated the proportion of OR pseudogenes in 19 primate species by surveying randomly chosen subsets of 100 OR genes from each species. We find that apes, Old World monkeys and one New World monkey, the howler monkey, have a significantly higher proportion of OR pseudogenes than do other New World monkeys or the lemur (a prosimian). Strikingly, the howler monkey is also the only New World monkey to possess full trichromatic vision, along with Old World monkeys and apes. Our findings suggest that the deterioration of the olfactory repertoire occurred concomitant with the acquisition of full trichromatic color vision in primates

Bearing account-able witness to the ethical algorithmic system

This paper explores how accountability might make otherwise obscure and inaccessible algorithms available for governance. The potential import and difficulty of accountability is made clear in the compelling narrative reproduced across recent popular and academic reports. Through this narrative we are told that algorithms trap us and control our lives, undermine our privacy, have power and an independent agential impact, at the same time as being inaccessible, reducing our opportunities for critical engagement. The paper suggests that STS sensibilities can provide a basis for scrutinizing the terms of the compelling narrative, disturbing the notion that algorithms have a single, essential characteristic and a predictable power or agency. In place of taking for granted the terms of the compelling narrative, ethnomethodological work on sense-making accounts is drawn together with more conventional approaches to accountability focused on openness and transparency. The paper uses empirical material from a study of the development of an “ethical,” “smart” algorithmic videosurveillance system. The paper introduces the “ethical” algorithmic surveillance system, the approach to accountability developed, and some of the challenges of attempting algorithmic accountability in action. The paper concludes with reflections on future questions of algorithms and accountability

Receiver development for BICEP Array, a next-generation CMB polarimeter at the South Pole

A detection of curl-type (B-mode) polarization of the primary CMB would be direct evidence for the inflationary paradigm of the origin of the Universe. The Bicep/Keck Array (BK) program targets the degree angular scales, where the power from primordial B-mode polarization is expected to peak, with ever-increasing sensitivity and has published the most stringent constraints on inflation to date. Bicep Array (BA) is the Stage-3 instrument of the BK program and will comprise four Bicep3-class receivers observing at 30/40, 95, 150 and 220/270 GHz with a combined 32,000+ detectors; such wide frequency coverage is necessary for control of the Galactic foregrounds, which also produce degree-scale B-mode signal. The 30/40 GHz receiver is designed to constrain the synchrotron foreground and has begun observing at the South Pole in early 2020. By the end of a 3-year observing campaign, the full Bicep Array instrument is projected to reach σr between 0.002 and 0.004, depending on foreground complexity and degree of removal of B-modes due to gravitational lensing (delensing). This paper presents an overview of the design, measured on-sky performance and calibration of the first BA receiver. We also give a preview of the added complexity in the time-domain multiplexed readout of the 7,776-detector 150 GHz receiver

Analysis of Temperature-to-Polarization Leakage in BICEP3 and Keck CMB Data from 2016 to 2018

The Bicep/Keck Array experiment is a series of small-aperture refracting telescopes observing degree-scale Cosmic Microwave Background polarization from the South Pole in search of a primordial B-mode signature. As a pair differencing experiment, an important systematic that must be controlled is the differential beam response between the co-located, orthogonally polarized detectors. We use high-fidelity, in-situ measurements of the beam response to estimate the temperature-to-polarization (T → P) leakage in our latest data including observations from 2016 through 2018. This includes three years of Bicep3 observing at 95 GHz, and multifrequency data from Keck Array. Here we present band-averaged far-field beam maps, differential beam mismatch, and residual beam power (after filtering out the leading difference modes via deprojection) for these receivers. We show preliminary results of "beam map simulations," which use these beam maps to observe a simulated temperature (no Q/U) sky to estimate T → P leakage in our real data

Observing low elevation sky and the CMB Cold Spot with BICEP3 at the South Pole

BICEP3 is a 520 mm aperture on-axis refracting telescope at the South Pole, which observes the polarization of the cosmic microwave background (CMB) at 95 GHz to search for the B-mode signal from inflationary gravitational waves. In addition to this main target, we have developed a low-elevation observation strategy to extend coverage of the Southern sky at the South Pole, where BICEP3 can quickly achieve degree-scale E-mode measurements over a large area. An interesting E-mode measurement is probing a potential polarization anomaly around the CMB Cold Spot. During the austral summer seasons of 2018-19 and 2019-20, BICEP3 observed the sky with a flat mirror to redirect the beams to various low elevation ranges. The preliminary data analysis shows degree-scale E-modes measured with high signal-to-noise ratio

Analysis of Temperature-to-Polarization Leakage in BICEP3 and Keck CMB Data from 2016 to 2018

The Bicep/Keck Array experiment is a series of small-aperture refracting telescopes observing degree-scale Cosmic Microwave Background polarization from the South Pole in search of a primordial B-mode signature. As a pair differencing experiment, an important systematic that must be controlled is the differential beam response between the co-located, orthogonally polarized detectors. We use high-fidelity, in-situ measurements of the beam response to estimate the temperature-to-polarization (T → P) leakage in our latest data including observations from 2016 through 2018. This includes three years of Bicep3 observing at 95 GHz, and multifrequency data from Keck Array. Here we present band-averaged far-field beam maps, differential beam mismatch, and residual beam power (after filtering out the leading difference modes via deprojection) for these receivers. We show preliminary results of "beam map simulations," which use these beam maps to observe a simulated temperature (no Q/U) sky to estimate T → P leakage in our real data