Abundance anomalies in pre-main-sequence stars: Stellar evolution models with mass loss

The effects of atomic diffusion on internal and surface abundances of A and F pre-main-sequence stars with mass loss are studied in order to determine at what age the effects materialize, as well as to further understand the processes at play in HAeBe and young ApBp stars. Self-consistent stellar evolution models of 1.5 to 2.8Msun with atomic diffusion (including radiative accelerations) for all species within the OPAL opacity database were computed and compared to observations of HAeBe stars. Atomic diffusion in the presence of weak mass loss can explain the observed abundance anomalies of pre-main-sequence stars, as well as the presence of binary systems with metal rich primaries and chemically normal secondaries such as V380 Ori and HD72106. This is in contrast to turbulence models which do not allow for abundance anomalies to develop on the pre-main-sequence. The age at which anomalies can appear depends on stellar mass. For A and F stars, the effects of atomic diffusion can modify both the internal and surface abundances before the onset of the MS. The appearance of important surface abundance anomalies on the pre-main-sequence does not require mass loss, though the mass loss rate affects their amplitude. Observational tests are suggested to decipher the effects of mass loss from those of turbulent mixing. If abundance anomalies are confirmed in pre-main-sequence stars they would severely limit the role of turbulence in these stars.Comment: 9 pages, 6 figures, accepeted for publicatio

Ribbon homology cobordisms

We study 4-dimensional homology cobordisms without 3-handles, showing that they interact nicely with Thurston geometries, character varieties, and instanton and Heegaard Floer homologies. Using these, we derive obstructions to such cobordisms, with topological applications.Comment: 50 pages, 6 figures. Major reorganization of sections for improved exposition. Result on Dehn surgery extended from Seifert fibered homology spheres to rational homology sphere

When Information Technology Design Favors Form over Function: Where is the Value-Added “Tipping Point”?

Performing usability analysis early in the design process results in lower overall development, deployment, and maintenance costs. Pre-development user and task analysis through questionnaires, observation, low-fidelity prototyping, and usability testing enables productive interactive testing of subsequent operable system prototypes. This helps assure a positive return on investment in information technology. When usercentered design assessment is supplanted by assumptions about user, task, and work environment, the result is often production of applications embellished with functionality unrelated to the user’s task. Surveys were administered to elicit user perception of system usability and usefulness and of satisfaction with intra-team interaction. This was the first step in determining the relationship between form and function for users of a Synchronous Distributed- Decision Support System (SD-DSS). It was anticipated that the teamwork process would be most troublesome while the SD-DSS would be perceived as easy to use and functional. The reverse proved to be the case

Whole-blood sorting, enrichment and in situ immunolabeling of cellular subsets using acoustic microstreaming

Analyzing undiluted whole human blood is a challenge due to its complex composition of hematopoietic cellular populations, nucleic acids, metabolites, and proteins. We present a novel multi-functional microfluidic acoustic streaming platform that enables sorting, enrichment and in situ identification of cellular subsets from whole blood. This single device platform, based on lateral cavity acoustic transducers (LCAT), enables (1) the sorting of undiluted donor whole blood into its cellular subsets (platelets, RBCs, and WBCs), (2) the enrichment and retrieval of breast cancer cells (MCF-7) spiked in donor whole blood at rare cell relevant concentrations (10 mL− 1), and (3) on-chip immunofluorescent labeling for the detection of specific target cellular populations by their known marker expression patterns. Our approach thus demonstrates a compact system that integrates upstream sample processing with downstream separation/enrichment, to carry out multi-parametric cell analysis for blood-based diagnosis and liquid biopsy blood sampling

Sirius A: turbulence or mass loss?

Context. Abundance anomalies observed in a fraction of A and B stars of both Pop I and II are apparently related to internal particle transport. Aims. Using available constraints from Sirius A, we wish to determine how well evolutionary models including atomic diffusion can explain observed abundance anomalies when either turbulence or mass loss is used as the main competitor to atomic diffusion. Methods. Complete stellar evolution models, including the effects of atomic diffusion and radiative accelerations, have been computed from the zero age main-sequence of 2.1M\odot stars for metallicities of Z0 = 0.01 \pm 0.001 and shown to agree with the observed parameters of Sirius A. Surface abundances were predicted for three values of the mass loss rate and for four values of the mixed surface zone. Results. A mixed mass of ~ 10^-6 M\odot or a mass loss rate of 10^-13 M\odot/yr were determined through comparison with observations. Of the 17 abundances determined observationally which are included in our calculations, up to 15 can be predicted within 2 sigmas and 3 of the 4 determined upper limits are compatible. Conclusions. While the abundance anomalies can be reproduced slightly better using turbulence as the process competing with atomic diffusion, mass loss probably ought to be preferred since the mass loss rate required to fit abundance anomalies is compatible with the observationally determined rate. A mass loss rate within a factor of 2 of 10^-13 M\odot/yr is preferred. This restricts the range of the directly observed mass loss rate.Comment: Accepted by A&A, 25/07/201