ANTIBACTERIAL AND PHOTOCATALYTIC ABILITY OF THE Ag/TiO2 COATING ON THE GLASS SURFACE.

The coating on the glass surface was made by heating the mixture of resinate Ag and tetra-n-butyl orthotitanate (TBO) at 570 oC for 1 hour. The characteristics and structure of the mixture Ag/TiO2 with the content of Ag : TiO2 from 0 – 8 (% mol) were studied by the methods such as XRD, FTIR, UV-viz, SEM, EDS. The research results of antibacterial ability and the degradation of blue methylene (MB) were shown that this coating can be used for antibacterial and photocatalytic abilit

Research on chemical constituents, anti-bacterial and anti-cancer effects of components isolated from Zingiber officinale Roscoe from Vietnam

Ginger, a commonly used spice and medicinal herb, is an abundant source of bioactive compounds. However, the utilization of ginger in the pharmaceutical industry is still moderate and not commensurate with the potential of the Vietnamese horticulture industry, mainly due to a lack of information about the quality of input materials. In this study, we compared the volatile compounds of gingers collected from 13 provinces of Vietnam using GC/MS and GC-FID analysis to provide a basis for selecting and standardizing input materials. Furthermore, ginger essential oil from Ben Tre province of Vietnam exhibited significant antibacterial activity particularly in inhibiting Gram-positive bacteria, including S. aureus and S. epidermidis, with inhibition zones of 30.00 ± 1.41 and 24.67 ± 3.30 mm, respectively. However, no significant inhibition was observed against Gram-negative bacteria P. aeruginosa and E. coli. We also isolated 5 non-volatile compounds from ginger extract, namely 6-shogaol (1), quercetin (2), rutin (3), beta-sitosterol (4) and beta-sitosterol-3-O-beta-D-glucopyranoside (5). Among them, compounds 1–3 displayed cytotoxicity against Hep3B, SK-LU-1, MCF-7, SK-LU-1, SW480 and HepG2 tumour cell lines, with an IC50 values ranging between 62.7 ± 2.1 and 97.6 ± 1.1 µM, using Ellipticine as a positive control. Compounds 4 and 5 showed cytotoxicity against Hep3B and HepG2 tumor cells, with the IC50 values ranging between 21.5 ± 5.1 and 46.9 ± 3.7 µM but did not exhibit any significant cytotoxicity against SW480 and SK-LU-1 cells. Compound 4 also demonstrated middling cytotoxicity against the MCF7 cell line, with an IC50 value of 43.6 ± 5.1 µM. These findings suggest further applications of Vietnamese ginger for the treatment of infectious and cancer-related diseases

KẾT QUẢ BƯỚC ĐẦU NGHIÊN CỨU KHU HỆ CÁ CỬA SÔNG THU BỒN, TỈNH QUANG NAM

This report presents the result of four surveys in 2013 at 12 sampling stations on fish composition of fish fauna in the Thu Bon estuary of Quang Nam province (the central Vietnam) and a total of 139 species of fishes were identified belonging to 110 genera, 63 families and 17 orders. Analysis of community structure of fish fauna showed that the order Perciformes was the most popular, making up 56.1%; Cypriniformes (8.6%); Pleuronectiformes (6.5%); Clupeiformes and Siluriformes (4.3%); Anguilliformes, Tetraodontiformes (3.6%); Mugiliformes (2.9%); ... The family Gobiidae was the most abundant with 12 species, making up 8.6% of the total number of species; Cyprinidae (10 species, 7.2%); Leiognathidae, Carangidae had the same number of species (6 species, 4.3%); Clupeidae, Lutjanidae: 5 species (3.6%); Serranidae, Mugilidae, Soleidae, Gerreidae, Ambassidae, Tetraodontidae: 4 species (2.9%); In addition, 4 families had 3 species, 12 families had 2 species and 35 families had 1 species. Cluster analysis based on the Bray - Curtis similarity index of nine fish faunas (Bach Dang, Thai Binh, Bu Lu, Son Tra peninsula, Thu Bon, coastal wetlands of Quang Nam, Nha Phu - Binh Cang, Ben Tre and Tra Vinh) showed that fish composition of the coastal - estuaries of Tra Vinh and Ben Tre had the highest similarity (78%), subsequently fish faunas of Thu Bon had similarity with that of Quang Nam (47%), Quang Nam and Nha Phu - Binh Cang (41%), Bu Lu and Thu Bon (38%). The result was also classified into three distinct groups of 9 fish faunas: group 1- Tra Vinh, Ben Tre and Thai Binh; group 2- Quang Nam, Thu Bon, Nha Phu - Binh Cang, Son Tra and Bu Lu; group 3- Bach Đang. The species richness (Margalef’s index) of Thu Bon (28.0) was less abundant than that of other areas: the highest species richness belonging to Tra Vinh (39.4), Thai Binh (38.6), Nha Phu - Binh Cang (35.9), Son Tra (31.8), Bu Lu (29.7), … The diversity of species composition according to the taxa in each region showed the characteristic of each fish fauna. The fish fauna is evidently typical of characteristics of the estuarine waters and coastal lagoons. There are 4 threatened species which are listed in the Vietnam’s Red Data Book (2007) at ex-tremely vulnerable levels.Thực hiện 4 chuyến khảo sát thu mẫu thành phần loài cá vùng cửa sông Thu Bồn trong năm 2013 tại 12 điểm thu mẫu. Kết quả đã ghi nhận được 139 loài thuộc 17 bộ, 63 họ và 110 giống. Phân tích cấu trúc quần xã khu hệ cá cho thấy: bộ cá Vược Perciformes là bộ cá phổ biến nhất chiếm 56,1%; tiếp đến là bộ cá Chép 8,6%; bộ cá Bơn Pleuronectiformes chiếm 6,5%; bộ cá Trích Clupeiformes và cá Nheo Siluriformes mỗi bộ 4,3%; bộ cá Chình Anguilliformes, cá Nóc Tetraodontiformes (3,6%); bộ cá Đối Mugiliformes (2,9%); ... Các họ chiếm ưu thế về loài: họ cá Bống trắng (Gobiidae) 12 loài chiếm 8,6% tổng số loài; cá Chép (Cyprinidae) 7,2%; cá Liệt (Leiognathidae) và cá Khế (Carangidae) mỗi họ 4,3%; cá Trích (Clupeidae), cá Hồng (Lutjanidae): 3,6%, ... So sánh với 8 khu hệ cá cửa sông - ven biển Việt Nam (Bạch Đằng, Thái Bình, Bù Lu, Sơn Trà, vùng đất ngập nước ven biển tỉnh Quảng Nam, Nha Phu - Bình Cang, Bến Tre và Trà Vinh) ghi nhận, vùng ven biển cửa sông Trà Vinh và Bến Tre có mức tương đồng cao nhất 78%, tiếp đến là Quảng Nam và Thu Bồn 47%, Quảng Nam và Nha Phu - Bình Cang 41%, Bu Lu và Thu Bồn 38%. Phân tích chỉ số giống nhau về thành phần loài của 9 khu hệ cá hình thành nên 3 nhóm: nhóm 1: Trà Vinh, Bến Tre và Thái Bình; nhóm 2: Quảng Nam, Thu Bồn, Nha Phu - Bình Cang, Sơn Trà và Bù Lu; Bạch Đằng hình thành riêng nhóm 3. Độ giàu có về loài của Thu Bồn đạt 28,0; Trà Vinh đạt cao nhất 39,4; tiếp đến là Thái Bình (38,6); Nha Phu - Bình Cang (35,9), Sơn Trà (31,8), Bù Lu (29,7), … Tính đa đạng về thành phần loài cá theo các bậc taxon trên từng vùng thể hiện tính đặc trưng riêng cho từng khu hệ. Các khu hệ cá thể hiện rõ tính chất nước lợ điển hình của các thuỷ vực cửa sông, đầm phá ven biển. Có 4 loài cá quý hiếm được ghi trong sách đỏ Việt Nam 2007 ở mức độ rất nguy cấp

The Impact of Social Presence in the Web Interface on Customer's Purchase Intention toward Online Stores: The Case of Vietnam

Abstract To date the expansion of information systems in the wa

Clinical Epidemiology Characteristics and Etiology of Febrile Neutropenia in Children: Analysis of 421 Cases

The congenital immune system includes neutrophils, which perform a variety of functions. Congenital and acquired neutropenia are rare illnesses with an underestimated prevalence in children. The aim of this study is to examine the epidemiology and etiology of febrile neutropenia in children at Haiphong Children’s Hospital, Haiphong, Vietnam. Methods: A cross-sectional study was carried out on 421 febrile neutropenia children. Clinical and laboratory characteristics were examined. Results: The median age (IQR) was 25.0 (12.5–59.5) months. The male-to-female ratio was 1.35/1. There were twice as many children living in the suburbs (66.98%) as in urban areas (33.02%). The mean (SD) temperature at admission was 38.50 ± 0.59 °C. Diagnosed causes associated with neutropenia included acute respiratory infections 250 (59.45%), gastrointestinal infections 68 (16.1%), erythema 37 (8.79%), acute leukemia 15 (3.56%), urinary tract infection 5 (1.19%), and encephalitis/meningitis 4 (0.95%). Viral etiology accounted for 61.52% (259): influenza type A—50.19% (130), influenza type B—31.27% (81), dengue virus—14.67% (38), measles virus 1—93% (5), rotavirus—1.54% (4), and EBV—0.4% (1). Twenty-five patients (5.94%) were found to have bacteria in their cultures, with Streptococcus pneumonia being the most common (eight patients; 32%). Conclusions: Febrile neutropenia was common in children under 2 years old. Primary clinical manifestations were acute upper respiratory tract infections, and viruses most commonly caused febrile neutropenia. Further studies with larger sample sizes are needed to determine the cause of febrile neutropenia

N,2,6-Trisubstituted 1H-benzimidazole derivatives as a new scaffold of antimicrobial and anticancer agents : design, synthesis, in vitro evaluation, and in silico studies

Compounds containing benzimidazole moiety occupy privileged chemical space for discovering new bioactive substances. In continuation of our recent work, 69 benzimidazole derivatives were designed and synthesized with good to excellent yields of 46-99% using efficient synthesis protocol i.e. sodium metabisulfite catalyzed condensation of aromatic aldehydes with o-phenylenediamines to form 2-arylbenzimidazole derivatives followed by N-alkylation by conventional heating or microwave irradiation for diversification. Potent antibacterial compounds against MSSA and MRSA were discovered such as benzimidazole compounds 3k (2-(4-nitrophenyl), N-benzyl), 3l (2-(4-chlorophenyl), N-(4-chlorobenzyl)), 4c (2-(4-chlorophenyl), 6-methyl, N-benzyl), 4g (2-(4-nitrophenyl), 6-methyl, N-benzyl), and 4j (2-(4-nitrophenyl), 6-methyl, N-(4-chlorobenzyl)) with MIC of 4-16 mu g mL(-1). In addition, compound 4c showed good antimicrobial activities (MIC = 16 mu g mL(-1)) against the bacteria strains Escherichia coli and Streptococcus faecalis. Moreover, compounds 3k, 3l, 4c, 4g, and 4j have been found to kill HepG2, MDA-MB-231, MCF7, RMS, and C26 cancer cells with low mu M IC50 (2.39-10.95). These compounds showed comparable drug-like properties as ciprofloxacin, fluconazole, and paclitaxel in computational ADMET profiling. Finally, docking studies were used to assess potential protein targets responsible for their biological activities. Especially, we found that DHFR is a promising target both in silico and in vitro with compound 4c having IC50 of 2.35 mu M

Adaptation of the U.S.-oriented evidence-based intervention TransAction for transgender women in Vietnam

Background: Trans women in Vietnam are among the most vulnerable groups with high HIV risk and limited access to care. TransAction is an evidence-based intervention to reduce trans women's HIV risks and increase social support and access to care.Aims: The aim of this study was to adapt TransAction to the specific needs of trans women in Vietnam. Methods: This study was conducted in Ho Chi Minh City from November 2020 through June 2021 Using the ADAPT-ITT framework, interviews, focus groups, and community advisory board meetings were conducted with trans women, service providers, and community members to better understand Vietnamese contexts of gender transition, HIV risks, and service gaps. Feedback was solicited on TransAction content and format adaptation. Results: Trans women in Vietnam faced unique challenges related to family norms, policy and regulatory constraints, and limited transgender-specific or gender-inclusive services. TransAction was modified to accommodate identified challenges and needs, and intervention components to enhance family support were added. Strategies to cope with stigma and seek support and services were adapted to Vietnamese culture and policies. Discussion: Post-adaptation interviews and focus groups demonstrated strong feasibility and acceptability for the adapted intervention, which can potentially be used to reduce Vietnamese trans women's HIV risks and increase their social support