Cardiac Defense Reactivity and Cognitive Flexibility in High- and Low-Resilience Women

The present study analyzes, in a sample of 54 young women, the relationships between high or low resilience, measured with the Connor- Davidson Resilience Scale questionnaire and the Spanish adaptation of the Resilience Scale, and two indices of psychophysiological and neuropsychological adaptability, the cardiac defense response (CDR) and cognitive flexibility. The results showed that the more resilient people, in addition to having better scores on mental health questionnaires, obtained better scores in cognitive flexibility than the less resilient people. Regarding the CDR, both groups showed the typical response pattern to unexpected intense noise, with two successive accelerationdeceleration components. However, the more resilient people had a larger initial acceleration-deceleration, which is indicative of greater vagal control, than the less resilient people. No significant differences were found in the second acceleration-deceleration, which is indicative of sympathetic control. The present findings broaden the understanding of how resilient people change their adaptable responses to address environmental demands.Project PSI2014-56924-P, funded by the Ministry of Economy and Competitivenes

Binuclear Cu2+ complex mediated discrimination between L-glutamate and L-aspartate in water

L-Glutamate and L-aspartate selectivity is achieved by the action of two Cu2+ metal ions rightly disposed in a cyclophanetype macrocyclic framework; electrochemical sensing of glutamate has been achieved by adsorption of the copper complexes on graphite electrodes.Verdejo Viu, Begoña, [email protected] ; Domenech Carbo, Antonio, [email protected] ; Jimenez Garcia, Hermas Rafael, [email protected] ; Soriano Soto, Concepción, [email protected] ; Garcia-España Monsonis, Enrique, [email protected]

La psicoeducación como estrategia para mejorar el apoyo familiar percibido del paciente con dependencia al alcohol y trastorno de la personalidad

The aim of this study was to prospectively analyze the impact of psychoeducation with relatives of addicted patients with personality disorders. We measured the impact of the psychoeducational intervention using a self-report questionnaire designed to assess perceived familiar support. The sample was composed by 37 patients with alcohol dependence following outpatient treatment. They underwent a cognitive-behavioral therapy relapse prevention program especially tailored for addicted individuals with comorbid personality disorders. 56.8% of patients followed individual therapy, and 43.2% followed group therapy. The relatives of the subgroup patients following group therapy simultaneously received the psychoeducational intervention. The analyses of the familiar support questionnaire across treatment showed a significant difference between groups as a function of treatment modality. Patients whose relatives followed the psychoeducational intervention had greater perception of familiar support throughout the treatment process.El objetivo de este estudio fue analizar longitudinalmente el impacto de la psicoeducación con familiares de pacientes que presentan un trastorno de la personalidad. Para medir parcialmente el efecto de la intervención se utilizó un cuestionario que evalúa el apoyo familiar percibido. La muestra estaba compuesta por 37 pacientes con trastorno p or dependencia del alcohol en tratamiento ambulatorio. Se llevó a cabo un programa de prevención de recaídas en el marco del modelo cognitivo conductual adaptado a las peculiaridades de la adicción en pacientes con trastornos de la personalidad. El 56.8 % de los pacientes siguieron tratamiento individual, mientras que el 43.2% lo hizo a nivel grupal. Los familiares de los pacientes que siguieron tratamiento grupal fueron objeto paralelamente de una intervención familiar individual basada en la psicoeducación. El análisis de las puntuaciones a lo largo del tratamiento mostró una clara diferencia entre los dos grupos de pacientes en función de la modalidad terapéutica. Los pacientes cuyos familiares fueron objeto de una intervención psicoeducativa sistemática adaptada a las particularidades de los rasgos de la personalidad en dependientes del alcohol, presentaron mejor percepción de apoyo familiar a lo largo del tratamient

La psicoeducación como estrategia para mejorar el apoyo familiar percibido del paciente con dependencia al alcohol y trastorno de la personalidad

The aim of this study was to prospectively analyze the impact of psychoeducation with relatives of addicted patients with personality disorders. We measured the impact of the psychoeducational intervention using a self-report questionnaire designed to assess perceived familiar support. The sample was composed by 37 patients with alcohol dependence following outpatient treatment. They underwent a cognitive-behavioral therapy relapse prevention program especially tailored for addicted individuals with comorbid personality disorders. 56.8% of patients followed individual therapy, and 43.2% followed group therapy. The relatives of the subgroup patients following group therapy simultaneously received the psychoeducational intervention. The analyses of the familiar support questionnaire across treatment showed a significant difference between groups as a function of treatment modality. Patients whose relatives followed the psychoeducational intervention had greater perception of familiar support throughout the treatment process.El objetivo de este estudio fue analizar longitudinalmente el impacto de la psicoeducación con familiares de pacientes que presentan un trastorno de la personalidad. Para medir parcialmente el efecto de la intervención se utilizó un cuestionario que evalúa el apoyo familiar percibido. La muestra estaba compuesta por 37 pacientes con trastorno p or dependencia del alcohol en tratamiento ambulatorio. Se llevó a cabo un programa de prevención de recaídas en el marco del modelo cognitivo conductual adaptado a las peculiaridades de la adicción en pacientes con trastornos de la personalidad. El 56.8 % de los pacientes siguieron tratamiento individual, mientras que el 43.2% lo hizo a nivel grupal. Los familiares de los pacientes que siguieron tratamiento grupal fueron objeto paralelamente de una intervención familiar individual basada en la psicoeducación. El análisis de las puntuaciones a lo largo del tratamiento mostró una clara diferencia entre los dos grupos de pacientes en función de la modalidad terapéutica. Los pacientes cuyos familiares fueron objeto de una intervención psicoeducativa sistemática adaptada a las particularidades de los rasgos de la personalidad en dependientes del alcohol, presentaron mejor percepción de apoyo familiar a lo largo del tratamiento

Update on Corneal Confocal Microscopy Imaging

In vivo corneal confocal microscopy (IVCM) is a non-invasive ophthalmic imaging technique that provides images of the cornea at the cellular level. Despite the uses in ocular surface pathologies, in the last decades IVCM has been used to provide more knowledge in refractive surgery wound healing, in neuropathies diagnosis, etc. The observation of the corneal cells, both normal and inflammatory, and the possibility of quantification of the corneal nerve density with manual or automated tools, makes IVCM have a significant potential to improve the diagnosis and prognosis in several systemic and corneal conditions

The sodium salt of diethyl 1H-pyrazole-3,5-dicarboxylate as an efficient amphiphilic receptor for dopamine and amphetamines. Crystal structure and solution studies

The sodium salt of the diethyl 1H-pyrazole-3,5-dicarboxylate (2) of amphiphilic character is able to interact with (+)-amphetamine, (+)-methamphetamine, and dopamine, yielding stable complexes. Crystal structure of 2 with (+)-amphetamine leads to a very nice double helical supramolecular structure.Financial support from CICYT (SAF 2003/ 02262 and CTQ2006-15672-CO5-01/BQU) is acknowledged. We also thank Mr. V. Gálvez for technical assistancePeer reviewe

Binuclear Cu2+ complex mediated discrimination between L-glutamate and L-aspartate in water

L-Glutamate and L-aspartate selectivity is achieved by the action of two Cu2+ metal ions rightly disposed in a cyclophane-type macrocyclic framework; electrochemical sensing of glutamate has been achieved by adsorption of the copper complexes on graphite electrodes