Liberal Egalitarianism and the Harm Principle

This paper analyses Rawls's celebrated difference principle, and its lexicographic extension, in societies with a finite and an infinite number of agents. A unified framework of analysis is set up, which allows one to characterise Rawlsian egalitarian principles by means of a weaker version of a new axiom - the Harm Principle - recently proposed by [12]. This is quite surprising, because the Harm principle is meant to capture a liberal requirement of noninterference and it incorporates no obvious egalitarian content. A set of new characterisations of the maximin and of its lexicographic refinement are derived, including in the intergenerational context with an infinite number of agents.Difference principle, Leximin, Weak harm principle, Infinite utility streams

Liberal Egalitarianism and the Harm Principle

This paper analyses Rawls's celebrated difference principle, and its lexicographic extension, in societies with a finite and an infinite number of agents. A unified framework of analysis is set up, which allows one to characterise Rawlsian egalitarian principles by means of a weaker version of a new axiom - the Harm Principle - recently proposed by [13]. This is quite surprising, because the Harm principle is meant to capture a liberal requirement of noninterference and it incorporates no obvious egalitarian content. A set of new characterisations of the maximin and of its lexicographic refinement are derived, including in the intergenerational context with an infinite number of agents.Difference principle, leximin, weak harm priciple, infinite utility streams

An Impossibility Result for Social Welfare Relations in Infinitely-lived Societies

This paper extends the analysis of liberal principles in social choice recently proposed by Mariotti and Veneziani ([6]) to societies with an infinite number of agents. First, a novel characterisation of the inegalitarian leximax social welfare relation is provided based on the Individual Benefit Principle, which incorporates a liberal, non-interfering view of society. This result is surprising because the IBP has no obvious anti-egalitarian content. Second, it is shown that there exists no weakly complete social welfare relation that satisfies simultaneously the standard axioms of Finite Anonymity, Strong Pareto, and Weak Continuity, and a liberal principle of Non-Interference that generalises IBP.Infinite utility streams, Individual Benefit Principle, leximax, Non-Interference, impossibility

Liberal Egalitarianism and the Harm Principle

This paper analyses the implications of classical liberal and libertarian approaches for distributive justice in the context of social welfare orderings. An axiom capturing a liberal non-interfering view of society, named the Weak Harm Principle, is studied, whose roots can be traced back to John Stuart Mill’s essay On Liberty. It is shown that liberal views of individual autonomy and freedom can provide consistent foundations for social welfare judgments, in both the finite and the infinite context. In particular, a liberal non-interfering approach can help to adjudicate some fundamental distributive issues relative to intergenerational justice. However, a surprisingly strong and general relation is established between liberal views of individual autonomy and non-interference, and egalitarian principles in the Rawlsian tradition

The contradiction of classical liberalism and libertarianism

Modern tools of economic analysis help show that key liberal principles lead logically to egalitarianism, write Michele Lombardi, Kaname Miyagishima and Roberto Venezian

Computational methods in cardiovascular mechanics

The introduction of computational models in cardiovascular sciences has been progressively bringing new and unique tools for the investigation of the physiopathology. Together with the dramatic improvement of imaging and measuring devices on one side, and of computational architectures on the other one, mathematical and numerical models have provided a new, clearly noninvasive, approach for understanding not only basic mechanisms but also patient-specific conditions, and for supporting the design and the development of new therapeutic options. The terminology in silico is, nowadays, commonly accepted for indicating this new source of knowledge added to traditional in vitro and in vivo investigations. The advantages of in silico methodologies are basically the low cost in terms of infrastructures and facilities, the reduced invasiveness and, in general, the intrinsic predictive capabilities based on the use of mathematical models. The disadvantages are generally identified in the distance between the real cases and their virtual counterpart required by the conceptual modeling that can be detrimental for the reliability of numerical simulations.Comment: 54 pages, Book Chapte

Are certified supply chains more socially sustainable? A bargaining power analysis

Food quality schemes (FQS: organic and geographical indication products) are often supposed to be more sustainable by their political advocates. We explore the social sustainability advantage of FQS through the lens of supply chains’ bargaining power (BP) distribution. We propose an indicator synthesizing different sources underlying BP (competition-based, transactional, institutional) and counting two dimensions (fair BP distribution and adaptation capacity), that we apply to 18 FQS supply chains and corresponding reference. FQS perform better than their reference products on both dimensions. This better performance is due to a combination of sources.Objectius de Desenvolupament Sostenible::12 - Producció i Consum ResponsablesPostprint (published version

Role of DNA repair machinery and p53 in the testicular germ cell cancer: a review

Notwithstanding the peculiar sensitivity to cisplatin-based treatment, resulting in a very high percentage of cures even in advanced stages of the disease, still we do not know the biological mechanisms that make Testicular Germ Cell Tumor (TGCT) "unique" in the oncology scene. p53 and MDM2 seem to play a pivotal role, according to several in vitro observations, but no correlation has been found between their mutational or expression status in tissue samples and patients clinical outcome. Furthermore, other players seem to be on stage: DNA Damage Repair Machinery (DDR) , especially Homologous Recombination (HR) proteins, above all Ataxia Telangiectasia Mutated (ATM), cooperates with p53 in response to DNA damage, activating apoptotic cascade and contributing to cell "fate". Homologous Recombination deficiency has been assumed to be a Germ Cell Tumor characteristic underlying platinum-sensitivity, whereby Poly(ADP-ribose) polymerase (PARP), an enzyme involved in HR DNA repair, is an intriguing target: PARP inhibitors have already entered in clinical practice of other malignancies and trials are recruiting TGCT patients in order to validate their role in this disease. This paper aims to summarize evidence, trying to outline an overview of DDR implications not only in TGCT curability, but also in resistance to chemotherapy

The Atacama Cosmology Telescope: A Measurement of the Cosmic Microwave Background Power Spectrum at 148 and 218 GHz from the 2008 Southern Survey

We present measurements of the cosmic microwave background (CMB) power spectrum made by the Atacama Cosmology Telescope at 148 GHz and 218 GHz, as well as the cross-frequency spectrum between the two channels. Our results clearly show the second through the seventh acoustic peaks in the CMB power spectrum. The measurements of these higher-order peaks provide an additional test of the {\Lambda}CDM cosmological model. At l > 3000, we detect power in excess of the primary anisotropy spectrum of the CMB. At lower multipoles 500 < l < 3000, we find evidence for gravitational lensing of the CMB in the power spectrum at the 2.8{\sigma} level. We also detect a low level of Galactic dust in our maps, which demonstrates that we can recover known faint, diffuse signals.Comment: 19 pages, 13 figures. Submitted to ApJ. This paper is a companion to Hajian et al. (2010) and Dunkley et al. (2010