46 research outputs found
Immune-mediated hookworm clearance and survival of a marine mammal decrease with warmer ocean temperatures
Indexación: Scopus.We appreciate the logistical support of the Chilean Navy, Artisanal fishermen of Quellon (Vessel crews Marimar II and Nautylus V), and the crews of the Chilean Navy lighthouse. We thank Amanda Hooper, Eugene DeRango, Elvira Vergara, Ignacio Silva, Dr. Lorraine Barbosa, Emma Milner, Sian Tarrant, Emily Morris, Suzette Miller, and Piero Becker for dedicated field assistance. We thank Dr. Vanesa Ezenwa for comments and insights in earlier versions of the manuscript. This work was supported by The Rufford Small Grant Foundation (Grant N 18815–1), Morris Animal Foundation (Grant N D16ZO-413), and the Society for Marine Mammalogy Small Grants in aid awards 2015 and 2016.Increases in ocean temperature are associated with changes in the distribution of fish stocks, and the foraging regimes and maternal attendance patterns of marine mammals. However, it is not well understood how these changes affect offspring health and survival. The maternal attendance patterns and immunity of South American fur seals were assessed in a rookery where hookworm disease is the main cause of pup mortality. Pups receiving higher levels of maternal attendance had a positive energy balance and a more reactive immune system. These pups were able to expel hookworms through a specific immune mediated mechanism and survived the infection. Maternal attendance was higher in years with low sea surface temperature, therefore, the mean hookworm burden and mortality increased with sea surface temperature over a 10-year period. We provide a mechanistic explanation regarding how changes in ocean temperature and maternal care affect infectious diseases dynamics in a marine mammal. © Seguel et al.https://elifesciences.org/articles/3843
Recommended from our members
Adaptación cultural al español del instrumento de evaluación de funcionalidad física en Unidad de Paciente Crítico: “The Chelsea Critical Care Physical Assessment Tool (CPAx)”
Las Unidades de Cuidados Intensivos (UCI), presentan una
sobrevida cada vez mayor de los pacientes que ingresan a ellas,
donde se ven enfrentados a una nueva entidad fisiopatológica
llamada Debilidad Muscular Adquirida en UCI (DAUCI).
Algunos test desarrollados para la evaluación de función motriz,
que permiten objetivar la progresión del paciente, son la escala
de fuerza muscular del Medical Research Council (MRC), el
Functional status score for the intensive care unit (FSS-ICU) y
el “Chelsea Critical Care Physical Assessment Tool (CPAx). La ventaja del CPAx radica en que este test incluye mayor información
asociada al funcionamiento humano como recomienda la OMS,
incorporando tanto el componente ventilatorio (que también se ve
deteriorado por DAUCI) como neuromuscular lo que permite
al profesional kinesiólogo tener una herramienta objetiva más
completa del nivel funcional del paciente.
Para que sea confiable, todo test debe ser validado en el país donde
quiere aplicarse, pero antes de esto debe ser adaptado culturalmente.
El objetivo de este trabajo fue efectuar la adaptación transcultural
(AT) al español del test de funcionalidad física de aplicación
kinésica CPAx. Se utilizó el proceso establecido por Beaton y cols
que incluye la formación de un comité de expertos multidisciplinario
que da una visión integral a la adaptación y una prueba piloto en
que kinesiólogos de UCI sin capacitación previa del test lo lean,
posteriormente lo apliquen y entreguen sus observaciones.
Conclusiones: Realizar la AT permite dimensionar la importancia
que tiene cada una de las etapas de este proceso. El test es el mismo,
equivalente al original, pero contiene nuestras características
culturales y condiciones técnicas, que lo hace ser comprensible y
aplicable en nuestro país. Esta adaptación transcultural también
es útil a nivel latinoamericano; para los países de habla hispana
que quieran validarlo tenerlo adaptado al español, hace el proceso
menos complejo.
Palabras clave: Evaluación funcional, Unidad de cuidados
intensivos, CPAx, adaptación transcultural
Tomographic and functional findings in severe COPD: comparison between the wood smoke-related and smoking-related disease
Neuroinflammation, Neuroautoimmunity, and the Co-Morbidities of Complex Regional Pain Syndrome
First Sagittarius A* Event Horizon Telescope results. II. EHT and multiwavelength observations, data processing, and calibration
We present Event Horizon Telescope (EHT) 1.3 mm measurements of the radio source located at the position of the supermassive black hole Sagittarius A* (Sgr A*), collected during the 2017 April 5–11 campaign. The observations were carried out with eight facilities at six locations across the globe. Novel calibration methods are employed to account for Sgr A*'s flux variability. The majority of the 1.3 mm emission arises from horizon scales, where intrinsic structural source variability is detected on timescales of minutes to hours. The effects of interstellar scattering on the image and its variability are found to be subdominant to intrinsic source structure. The calibrated visibility amplitudes, particularly the locations of the visibility minima, are broadly consistent with a blurred ring with a diameter of ∼50 μas, as determined in later works in this series. Contemporaneous multiwavelength monitoring of Sgr A* was performed at 22, 43, and 86 GHz and at near-infrared and X-ray wavelengths. Several X-ray flares from Sgr A* are detected by Chandra, one at low significance jointly with Swift on 2017 April 7 and the other at higher significance jointly with NuSTAR on 2017 April 11. The brighter April 11 flare is not observed simultaneously by the EHT but is followed by a significant increase in millimeter flux variability immediately after the X-ray outburst, indicating a likely connection in the emission physics near the event horizon. We compare Sgr A*'s broadband flux during the EHT campaign to its historical spectral energy distribution and find that both the quiescent emission and flare emission are consistent with its long-term behavior.http://iopscience.iop.org/2041-8205Physic
First Sagittarius A* Event Horizon Telescope Results. II. EHT and Multiwavelength Observations, Data Processing, and Calibration
We present Event Horizon Telescope (EHT) 1.3 mm measurements of the radio source located at the position of the supermassive black hole Sagittarius A* (Sgr A*), collected during the 2017 April 5–11 campaign. The observations were carried out with eight facilities at six locations across the globe. Novel calibration methods are employed to account for Sgr A*'s flux variability. The majority of the 1.3 mm emission arises from horizon scales, where intrinsic structural source variability is detected on timescales of minutes to hours. The effects of interstellar scattering on the image and its variability are found to be subdominant to intrinsic source structure. The calibrated visibility amplitudes, particularly the locations of the visibility minima, are broadly consistent with a blurred ring with a diameter of ∼50 μas, as determined in later works in this series. Contemporaneous multiwavelength monitoring of Sgr A* was performed at 22, 43, and 86 GHz and at near-infrared and X-ray wavelengths. Several X-ray flares from Sgr A* are detected by Chandra, one at low significance jointly with Swift on 2017 April 7 and the other at higher significance jointly with NuSTAR on 2017 April 11. The brighter April 11 flare is not observed simultaneously by the EHT but is followed by a significant increase in millimeter flux variability immediately after the X-ray outburst, indicating a likely connection in the emission physics near the event horizon. We compare Sgr A*’s broadband flux during the EHT campaign to its historical spectral energy distribution and find that both the quiescent emission and flare emission are consistent with its long-term behavior
Previous cultivation of palisade grass and soil correctives: influence on growth and yield of soybean cultivated under various soil compaction levels Cultivo prévio de braquiarão e corretivos de solo: influência sobre o crescimento e produção da soja cultivada sob vários níveis de compactação do solo
Soil compaction directly interferes on crop yield. The objectives of this work were to evaluate the effect of previous cultivation with palisade grass [Urochloa brizantha (C. Hochstetter ex A. Rich.) R. Webster cv. Marandu] and the use of soil correctives on the growth and yield of soybeans (Glycine max L.) cultivated under various soil compaction levels, in greenhouse conditions. The experiment was conducted in pots (columns) of 0.2 m diameter PVC tubes, composed of two rings: the lower ring, 0.4 m in height, received the soil (dystrophic Red Latosol, clayey texture) without corrective and a density of 1.0 Mg m-3; and the upper ring, 0,2 m in height, received the treatments of soil correctives and density. The experimental design was fully randomized in a 4 x 6 x 2 factorial outline, being four soil density levels (1.0; 1.20; 1.40 and 1.60 Mg m-3), six soil correctives (without corrective, lime, calcium silicate, gypsum, lime + gypsum and calcium silicate + gypsum) and two cultivation systems of the soybean (with and without previous cultivation of palisade grass). Starting from 1.2 Mg m-3 of soil density the soybean growth and yield were decreased. The use of soil correctives and previous soil cultivation with palisade grass decreased the harmful effects of the soil compaction on the soybean growth and yield. For the treatments that received previous cultivation with palisade grass, the soybean growth and yield were higher with application of lime + gypsum and calcium silicate + gypsum.<br>A compactação do solo interfere diretamente sobre a produção das culturas. Neste trabalho, objetivou-se avaliar o efeito do cultivo prévio do braquiarão e o uso de corretivos do solo sobre o crescimento e produção da soja cultivada sob solo com vários níveis de compactação, em condições de casa de vegetação. O experimento foi conduzido em vasos (colunas) de tubos de PVC de 0,2 m de diâmetro, compostos por dois anéis: o anel inferior, de 0,4 m de altura, recebeu o solo (Latossolo Vermelho distrófico de textura argilosa) sem corretivo e densidade de 1,0 Mg m-3; e o anel superior, com 0,2 m de altura, recebeu os tratamentos de corretivos do solo (sem correção, calcário, silicato de cálcio, gesso, calcário + gesso e silicato de cálcio + gesso) e de compactação (1,0; 1,20; 1,40 e 1,60 Mg m-3 de densidade) do solo. O delineamento experimental foi inteiramente casualizado em esquema fatorial 4 x 6 x 2, sendo quatro densidades de solo, seis corretivos de solo e dois sistemas de cultivo da soja, com e sem cultivo prévio do braquiarão. A partir de 1,2 Mg m-3 de densidade de solo, foi observada redução no crescimento e produção de grãos da soja. O uso de corretivos e o cultivo prévio do solo com braquiarão amenizam os efeitos deletérios da compactação do solo sobre o crescimento e produção da soja. Para os tratamentos que receberam cultivo prévio de braquiarão, a mistura de calcário + gesso e silicato de cálcio + gesso foram os corretivos que proporcionaram maior crescimento e produção da soja