Sahel decadal rainfall variability and the role of model horizontal resolution

Substantial low-frequency rainfall fluctuations occurred in the Sahel throughout the twentieth century, causing devastating drought. Modeling these low-frequency rainfall fluctuations has remained problematic for climate models for many years. Here we show using a combination of state-of-the-art rainfall observations and high-resolution global climate models that changes in organized heavy rainfall events carry most of the rainfall variability in the Sahel at multiannual to decadal time scales. Ability to produce intense, organized convection allows climate models to correctly simulate the magnitude of late-twentieth century rainfall change, underlining the importance of model resolution. Increasing model resolution allows a better coupling between large-scale circulation changes and regional rainfall processes over the Sahel. These results provide a strong basis for developing more reliable and skilful long-term predictions of rainfall (seasons to years) which could benefit many sectors in the region by allowing early adaptation to impending extremes

The impact of equilibrating hemispheric albedos on tropical performance in the HadGEM2-ES coupled climate model

AcceptedArticle in Press©2015. The Authors. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.©2015. The Authors. The Earth's hemispheric reflectances are equivalent to within±0.2Wm-2, even though the Northern Hemisphere contains a greater proportion of higher reflectance land areas, because of greater cloud cover in the Southern Hemisphere. This equivalence is unlikely to be by chance, but the reasons are open to debate. Here we show that equilibrating hemispheric albedos in the Hadley Centre Global Environment Model version 2-Earth System coupled climate model significantly improves what have been considered longstanding and apparently intractable model biases. Monsoon precipitation biases over all continental land areas, the penetration of monsoon rainfall across the Sahel, the West African monsoon "jump", and indicators of hurricane frequency are all significantly improved. Mechanistically, equilibrating hemispheric albedos improves the atmospheric cross-equatorial energy transport and increases the supply of tropical atmospheric moisture to the Hadley cell. We conclude that an accurate representation of the cross-equatorial energy transport appears to be critical if tropical performance is to be improved

The impact of equilibrating hemispheric albedos on tropical performance in the HadGEM2-ES coupled climate model

The Earth's hemispheric reflectances are equivalent to within ± 0.2 Wm-2, even though the Northern Hemisphere contains a greater proportion of higher reflectance land areas, because of greater cloud cover in the Southern Hemisphere. This equivalence is unlikely to be by chance, but the reasons are open to debate. Here we show that equilibrating hemispheric albedos in the Hadley Centre Global Environment Model version 2-Earth System coupled climate model significantly improves what have been considered longstanding and apparently intractable model biases. Monsoon precipitation biases over all continental land areas, the penetration of monsoon rainfall across the Sahel, the West African monsoon 'jump', and indicators of hurricane frequency are all significantly improved. Mechanistically, equilibrating hemispheric albedos improves the atmospheric cross-equatorial energy transport and increases the supply of tropical atmospheric moisture to the Hadley cell. We conclude that an accurate representation of the cross-equatorial energy transport appears to be critical if tropical performance is to be improved

Controls on upstream-migrating bed forms in sandy submarine channels

Submarine channels parallel river channels in their ability to transport sediment. However, in contrast to rivers, sediment transport and bed-form development in submarine channels are less well understood. Many steep (>1°), sandy submarine channels are dominated by upstream-migrating bed forms. The flow conditions required to form these upstream-migrating bed forms remain debated because the interactions between turbidity currents and active bed forms are difficult to measure directly. Consequently, we used a depth-resolved numerical model to test the role of flow parameters that are hypothesized to control the formation of upstream-migrating bed forms in submarine channels. While our modeling results confirmed the importance of previously identified flow parameters (e.g., densiometric Froude number), we found that basal sediment concentration in turbidity currents is the strongest predictor of upstream-migrating bed-form formation. Our model shows how locally steep gradients enable high sediment concentrations (average >5 vol%) in the basal parts of flows, which allow the development of cyclic step instabilities and their associated bed forms. This new insight explains the previously puzzling observation that upstream-migrating bed forms are abundant in proximal, steep, sandy reaches of submarine channels, while their occurrence becomes more intermittent downslope

Is a shutdown of the thermohaline circulation irreversible?

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/94891/1/jgrd12573.pd

Genetic Incorporation of Human Metallothionein into the Adenovirus Protein IX for Non-Invasive SPECT Imaging

As the limits of existing treatments for cancer are recognized, clearly novel therapies must be considered for successful treatment; cancer therapy using adenovirus vectors is a promising strategy. However tracking the biodistribution of adenovirus vectors in vivo is limited to invasive procedures such as biopsies, which are error prone, non-quantitative, and do not give a full representation of the pharmacokinetics involved. Current non-invasive imaging strategies using reporter gene expression have been applied to analyze adenoviral vectors. The major drawback to approaches that tag viruses with reporter genes is that these systems require initial viral infection and subsequent cellular expression of a reporter gene to allow non-invasive imaging. As an alternative to conventional vector detection techniques, we developed a specific genetic labeling system whereby an adenoviral vector incorporates a fusion between capsid protein IX and human metallothionein. Our study herein clearly demonstrates our ability to rescue viable adenoviral particles that display functional metallothionein (MT) as a component of their capsid surface. We demonstrate the feasibility of 99mTc binding in vitro to the pIX-MT fusion on the capsid of adenovirus virions using a simple transchelation reaction. SPECT imaging of a mouse after administration of a 99mTc-radiolabeled virus showed clear localization of radioactivity to the liver. This result strongly supports imaging using pIX-MT, visualizing the normal biodistribution of Ad primarily to the liver upon injection into mice. The ability we have developed to view real-time biodistribution in their physiological milieu represents a significant tool to study adenovirus biology in vivo

Monoculture of Leafcutter Ant Gardens

Background -- Leafcutter ants depend on the cultivation of symbiotic Attamyces fungi for food, which are thought to be grown by the ants in single-strain, clonal monoculture throughout the hundreds to thousands of gardens within a leafcutter nest. Monoculture eliminates cultivar-cultivar competition that would select for competitive fungal traits that are detrimental to the ants, whereas polyculture of several fungi could increase nutritional diversity and disease resistance of genetically variable gardens. Methodology/Principal Findings -- Using three experimental approaches, we assessed cultivar diversity within nests of Atta leafcutter ants, which are most likely among all fungus-growing ants to cultivate distinct cultivar genotypes per nest because of the nests' enormous sizes (up to 5000 gardens) and extended lifespans (10–20 years). In Atta texana and in A. cephalotes, we resampled nests over a 5-year period to test for persistence of resident cultivar genotypes within each nest, and we tested for genetic differences between fungi from different nest sectors accessed through excavation. In A. texana, we also determined the number of Attamyces cells carried as a starter inoculum by a dispersing queens (minimally several thousand Attamyces cells), and we tested for genetic differences between Attamyces carried by sister queens dispersing from the same nest. Except for mutational variation arising during clonal Attamyces propagation, DNA fingerprinting revealed no evidence for fungal polyculture and no genotype turnover during the 5-year surveys. Conclusions/Significance -- Atta leafcutter ants can achieve stable, fungal monoculture over many years. Mutational variation emerging within an Attamyces monoculture could provide genetic diversity for symbiont choice (gardening biases of the ants favoring specific mutational variants), an analog of artificial selection.The research was supported by National Science Foundation awards DEB-0920138, DEB-0639879, and DEB-0110073 to UGM; DEB-0949689 to T.R. Schultz, N. Mehdiabadi, and UGM; and a Fellowship (02/05) from the Conselho Nacional de Desenvolvimento Científico e Tecnológico to AR. The funding agencies had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Biological Sciences, School o