DISEÑO Y CONSTRUCCIÓN DE UN ROBOT BÍPEDO EXPERIMENTAL

En la actualidad nuevas tecnologías y ramas de la investigación hanvolcado su atención hacia la comunidad científica; entre ellas tenemos a la genética, la exploración del espacio, la robótica, etc., todas éstas con grandes e importantes aplicaciones, pero con una complejidad que requiere de la participación de una mayor cantidad y calidad de científicos en todo el mundo

Antibacterial and cytotoxic activities of naphthoquinone pigments from Onosma visianii Clem

In this study, the antibacterial and cytotoxic activities of isolated compounds from the roots of Onosma visianii were investigated. By using different chromatographic techniques and appropriate spectroscopic methods, the seven naphthoquinones were described: deoxyshikonin (1), isobutyrylshikonin (2), α-methylbutyrylshikonin (3), acetylshikonin (4), ß-hydroxyisovalerylshikonin (5), 5,8-O-dimethyl isobutyrylshikonin (6) and 5,8-O-dimethyl deoxyshikonin (7). Among the tested compounds, 3 and 4 exhibited the highest antibacterial activities toward all tested bacterial species (MIC50 and MIC90 for gram positive bacteria: 6.40 µg/mL-12.79 µg/mL and 6.82 µg/mL-13.60 µg/mL, respectively; for gram negative bacteria: 4.27 µg/mL-8.53 µg/mL and 4.77 µg/mL-9.54 µg/mL, respectively). Also, naphthoquinones 3 and 4 exhibited strong cytotoxic activity against MDA-MB-231 cells (IC50 values 86.0 µg/mL and 80.2 µg/mL, respectively), while compounds 1, 3, 4 and 5 significantly decreased viability of HCT116 cells (IC50 values of 97.8 µg/mL, 15.2 µg/mL, 24.6 µg/mL and 30.9 µg/mL, respectively). Our results indicated that all tested naphthoquinone pigments are potential candidates for clinical uses as antibacterial and cytotoxic agents

Review of dental workforce development and utilisation in Papua New Guinea

When Papua New Guinea gained political independence from Australia in September 1975 it developed its own internal political system. One of the major political developments that took place was the decentralisation of decision making powers from the Central Government to the provinces which led to the creation of a Provincial Government system. Thus the health functions, including dental, were transferred to the Provincial Governments except for some nationally important health functions which remained with the National Department of Health. The decentralisation of health functions affected the dental services in the provinces, in particular the school dental service

The Management and Stewardship of A Cetacean Collection

Cetacean, by definition, is a marine mammal of the order Cetacea; a whale, dolphin or porpoise. In light of their social intellect and friendly appearance, cetaceans are used in institutions such as zoos and aquariums as a source of education and entertainment for the public. Before the Marine Mammal Protection Act of 1972, cetaceans were captured worldwide including in U.S. waters. In the United States today, there are over 224 zoos and aquariums accredited by the Association of Zoos and Aquariums. Out of those 224, 34 of these institutions display cetaceans. Even though the Marine Mammal Protection Act “Prohibits, with certain exceptions, the “taking” of marine mammals in U. S waters and by U. S. citizens on the high seas, and the importation of marine mammals and marine mammal products. (NOAA Fisheries.), U.S. aquariums and institutions are able to apply for permits that allow the importation of marine mammals. Due to recent events and the documentary Blackfish, for-profit and nonprofit zoos and aquariums are being questioned on the care and display of these particular animals. With newly developed scientific evidence showing the psychological similarities between humans and cetaceans, activists and cetacean scientists believe that cetacean captivity might be drawing to an end. This thesis addresses the management and stewardship of maintaining cetaceans in captivity and the ethical and unethical practices that are found in zoos and aquariums. This thesis will also discuss the history of cetacean captivity and how throughout the years governmental laws and code of ethics have altered in order for institutions to maintain their collection. Through research, this thesis will allow its readers to decide whether the management of zoos and aquariums use their cetacean collections for the benefit of educating the public on the importance of conserving these animals and their wild populations, or for the benefit of the institutions themselves

The effects of the cherry variety on the chemical and sensorial characteristics of cherry brandy

The chemical and sensorial characteristics of cherry brandy produced from five cherry varieties (Oblacinska, Celery’s 16, Rexle, Heiman’s Ruby and Heiman’s Conserve) grown in Serbia were studied. Gas chromatography and gas chromatography–mass spectrometry analysis of these distillates led to the identification of 32 components, including 20 esters, benzaldehyde, 6 terpenes and 5 acids. The ethyl esters of C8–C18 acids were the most abundant in all samples. The benzaldehyde content was quantified by high performance liquid chromatography with UV detection. The average benzaldehyde concentration in the samples ranged between 2.1 and 24.1 mg L-1. The total sensory scores of the cherry brandies ranged between 17.30 to 18.05, with the cherry brandy produced from the Celery’s 16 variety receiving the highest score (18.05)

Mogućnosti smanjivanja sadržaja metanola u rakiji šljivovici

Several methods for reducing the methanol content of plum brandies were tried: possibilities for its reduced forming during fruit must alcohol fermentation, and employing effective and rational methods in order to decrease the already existing amount of methanol by applying demethanolization column. Apart from numerous valued components, plum brandy also contains some undesirable ingredients, among which methanol has a special place. It appears during hydrolysis of pectin substances under the influence of the specific pectolytic enzymes, pectyn-methyl-esterasis in particular. A certain amount still has to be present in natural brandies in order to maintain the authentic fruit origin. Reduction of the existing methanol amounts by applying demethanolization column was most effective and came to 43-77% in comparison to the starting amount.Predmet ovog istraživanja bio je pronalaženje različitih mogućnosti za smanjivanje količine metanola u rakiji šljivovici. Pored velikog broja drugih komponenti rakija šljivovica sadrži i neke neželjene sastojke, među kojima metanol zauzima specijalno mesto. Metanol nastaje tokom hidrolize jedinjenja pektinskog tipa, a pod uticajem pektolitičkog enzima pektin-metil-esteraze. Određeno prisustvo metanola predstavlja dokaz autentičnog voćnog porekla rakije. Istraživanja u ovom radu su se odnosila na mogućnosti snižavanja sadržaja metanola u rakijama šljivovicama od sorti požegače, stenli i džanarika a tekla su u dva pravca: 1. Na iznalaženju najpogodnijeg postupka za manje nastajanje metanola tokom alkoholne fermentacije kljuka šljive (uticaj pH kljuka, uticaj vremena čekanja pre destilacije i uticaj različitih izazivača vrenja). 2. Ispitivanje i pronalaženje najracionalnijeg načina za smanjivanje već postojećih količina metanola u šljivovici tokom izvođenja demetanolizacione rektifikacije. Eksperimenti vezani za smanjenje formiranja metanola tokom alkoholne fermentacije su rađeni sa tri sorte šljiva: požegača, stenli i džanarika dobijenih od preduzeća "Srbijanka" Co.-Valjevo i "Podgorka" Co.-Osečina, dok su eksperimenti redukcije metanola pomoću demetanolizacione kolone izvođeni sa rakijom šljivovicom iz "Podgorka" Co.-Osečina, region Ostružanj-Podgorina. Količina metanola je određivana metodom gasne hromatografije uz primenu kapilarne kolone. Dobijeni rezultati pokazuju da je najveće smanjenje u formiranju metanola tokom fermentacije kljuka pri pH 2,5. Povećanje sadržaja metanola u sve tri sorte i svim varijantama je u direktnoj korelaciji sa vremenom koje protekne pre destilacije kljuka. Ovo je dokaz više da se hidroliza pektinskih supstanci nastavlja sa smanjenim intenzitetom tokom vremena čekanja pre destilacije. Odabrani tipovi kvasaca koji ne proizvode pektinesterze mogu biti odabrani za smanjenje količine metanola. Eksperimentalni rezultati sa kolonom za demetanolizaciju pokazuju da je smanjenje zavisno od eksperimentalne varijante moguće od 45%-75% u odnosu na količinu u kontrolnom uzorku

Pyrrolizidine alkaloids from seven wild-growing Senecio species in Serbia and Montenegro

The genus Senecio (family Asteraceae) is one of the largest in the world. It comprises about 1100 species which are the rich source of pyrrolizidine alkaloids. Plants containing pyrrolizidine alkaloids are among the most important sources of human and animal exposure to plant toxins and carcinogens. The pyrrolizidine alkaloids of seven Senecio species (S. erucifolius, S. othonnae, S. wagneri, S. subalpinus, S. carpathicus, S. paludosus and S. rupestris) were studied. Fourteen alkaloids were isolated and their structures determined from spectroscopic data (1H- and 13C-NMR, IR and MS). Five of them were identified in S. erucifolius, four in S. othonnae, two in S. wagneri, four in S. subalpinus, two in S. carpathicus, three in S. paludosus and three in S. rupestris. Seven pyrrolizidine alkaloids were found for the first time in particular species. The results have chemotaxonomic importance. The cytotoxic activity and antimicrobial activity of some alkaloids were also studied

Decentralised additive manufacturing for architecture: exploring the integration of distributed ledger technologies with 3D printing.

This paper investigates the potential integration of blockchain and distributed ledger technologies with Additive Manufacturing in the context of architectural design and fabrication. The study aims to identify knowledge gaps, explore the affinity between these technologies, and challenge the current architecture production paradigm. Through a comprehensive state-of-the-art review and analysis of academic papers and industrial case studies, we identified emerging themes and gaps in the literature. We also examined the misalignment of incentives among key participants of the proposed systems. Our findings highlighted the relevance of blockchain technology in additive manufacturing, but also revealed significant challenges and misalignments in incentives among stakeholders. We argue that further research and experimentation are necessary to fully understand the technical feasibility and impact of integrating these technologies in architectural design and fabrication

Decentralised Additive Manufacturing for Architecture:Exploring the integration of distributed ledger technologies with 3D printing

This paper investigates the potential integration of blockchain and distributed ledger technologies with Additive Manufacturing in the context of architectural design and fabrication. The study aims to identify knowledge gaps, explore the affinity between these technologies, and challenge the current architecture production paradigm. Through a comprehensive state-of-the-art review and analysis of academic papers and industrial case studies, we identified emerging themes and gaps in the literature. We also examined the misalignment of incentives among key participants of the proposed systems. Our findings highlighted the relevance of blockchain technology in additive manufacturing, but also revealed significant challenges and misalignments in incentives among stakeholders. We argue that further research and experimentation are necessary to fully understand the technical feasibility and impact of integrating these technologies in architectural design and fabrication

Decentralised Additive Manufacturing for Architecture:Exploring the integration of distributed ledger technologies with 3D printing

This paper investigates the potential integration of blockchain and distributed ledger technologies with Additive Manufacturing in the context of architectural design and fabrication. The study aims to identify knowledge gaps, explore the affinity between these technologies, and challenge the current architecture production paradigm. Through a comprehensive state-of-the-art review and analysis of academic papers and industrial case studies, we identified emerging themes and gaps in the literature. We also examined the misalignment of incentives among key participants of the proposed systems. Our findings highlighted the relevance of blockchain technology in additive manufacturing, but also revealed significant challenges and misalignments in incentives among stakeholders. We argue that further research and experimentation are necessary to fully understand the technical feasibility and impact of integrating these technologies in architectural design and fabrication