JME 4110: Plant Tissue Sampler

This document contains the design for a device to take plant tissue samples from a plants leaves. Within the report are design ideas, final design, rationale behind design choices based off of customer interviews, relevant codes and standards, bill of materials, and part drawings. The final drawings of the device and its parts are included along with pictures with descriptions of the parts and video links of a demonstration and presentation

Prospectus, April 10, 1996

https://spark.parkland.edu/prospectus_1996/1011/thumbnail.jp

Whiteboard Drawing Device

Whiteboards have become a staple in many classrooms, especially in the context of STEM courses. However, when it comes to teaching complex topics, it can be difficult or impractical to provide accurate drawings and visualizations by hand, and in extreme cases may lead to misinterpretation of a particular topic. To fix this issue, the Whiteboard Drawing Device allows users to draw preset shapes to a whiteboard automatically, both quickly and accurately. Using either a smartphone application or a set of onboard controls, the device allows users to automatically draw straight lines, rectangles, triangles, sinusoidal waves, and circles on the whiteboard. The shape, size, and position of each of these shapes on the board are defined by the user, and the device can be retrofitted to a whiteboard of max size 4’ × 4’. With this, the Whiteboard Drawing Device offers a user-friendly, low-cost, and fun alternative to other more expensive products with similar functionality

Molecular Dynamics Simulations Reveal the Protective Role of Cholesterol in β-Amyloid Protein-Induced Membrane Disruptions in Neuronal Membrane Mimics

Interactions of β-amyloid (Aβ) peptides with neuronal membranes have been associated with the pathogenesis of Alzheimer\u27s disease (AD); however, the molecular details remain unclear. We used atomistic molecular dynamics (MD) simulations to study the interactions of Aβ40 and Aβ42 with model neuronal membranes. The differences between cholesterol-enriched and depleted lipid domains were investigated by the use of model phosphatidylcholine (PC) lipid bilayers with and without 40 mol % cholesterol. A total of 16 independent 200 ns simulation replicates were investigated. The surface area per lipid, bilayer thickness, water permeability barrier, and lipid order parameter, which are sensitive indicators of membrane disruption, were significantly altered by the inserted state of the protein. We conclude that cholesterol protects Aβ-induced membrane disruption and inhibits β-sheet formation of Aβ on the lipid bilayer. The latter could represent a two-dimensional (2D) seeding template for the formation of toxic oligomeric Aβ in the pathogenesis of AD

Prospectus, October 4, 1995

https://spark.parkland.edu/prospectus_1995/1023/thumbnail.jp

Prospectus, August 30, 1995

https://spark.parkland.edu/prospectus_1995/1018/thumbnail.jp

F17RS SGR No. 3 (Charlottesville)

A RESOLUTION Standing in Solidarity with Charlottesville, Virginia, and the University of Virginia following the Events of August 11-12, 201

The Heliopause Electrostatic Rapid Transit System (HERTS) - Design, Trades, and Analyses Performed in a Two Year NASA Investigation of Electric Sail Propulsion Systems

Personnel from NASA's MSFC have been investigating the feasibility of an advanced propulsion system known as the Electric Sail (E-Sail) for future scientific exploration missions. This team initially won a NASA Space Technology Mission Directorate (STMD) Phase I NASA Innovative Advanced Concept (NIAC) award and then a two-year follow-on Phase II NIAC award in October 2015. This paper documents the findings from this three-year investigation. An Electric sail, a propellant-less propulsion system, uses solar wind ions to rapidly travel either to deep space or the inner solar system. Scientific spacecraft could reach Pluto in ~5 years, or the boundary of the solar system in ten to twelve years compared to the thirty-five plus years the Voyager spacecraft took. The team's recent focuses have been: 1) Developing a Particle in Cell (PIC) numeric engineering model from MSFC's experimental data on the interaction between simulated solar wind and a charged bare wire that can be applied to a variety of missions, 2) Determining what missions could benefit from this revolutionary propulsion system, 3) Conceptualizing spacecraft designs for various tasks: to reach the solar system's edge, to orbit the sun as Heliophysics sentinels, or to examine a multitude of asteroids

Measuring Pain in Sickle Cell Disease using Clinical Text

Sickle Cell Disease (SCD) is a hereditary disorder of red blood cells in humans. Complications such as pain, stroke, and organ failure occur in SCD as malformed, sickled red blood cells passing through small blood vessels get trapped. Particularly, acute pain is known to be the primary symptom of SCD. The insidious and subjective nature of SCD pain leads to challenges in pain assessment among Medical Practitioners (MPs). Thus, accurate identification of markers of pain in patients with SCD is crucial for pain management. Classifying clinical notes of patients with SCD based on their pain level enables MPs to give appropriate treatment. We propose a binary classification model to predict pain relevance of clinical notes and a multiclass classification model to predict pain level. While our four binary machine learning (ML) classifiers are comparable in their performance, Decision Trees had the best performance for the multiclass classification task achieving 0.70 in F-measure. Our results show the potential clinical text analysis and machine learning offer to pain management in sickle cell patients.Comment: The 42nd Annual International Conference of the IEEE Engineering in Medicine and Biology Societ

Prospectus, December 13, 1995

https://spark.parkland.edu/prospectus_1995/1033/thumbnail.jp