4,970 research outputs found
Bystander B cells rapidly acquire antigen receptors from activated B cells by membrane transfer: a novel mechanism for enhancing specific antigen presentation
The B cell antigen receptor (BCR) efficiently facilitates the capture and processing of a specific antigen for presentation on MHC class II molecules to antigen specific CD4+ T cells (1). Despite this, the majority of B cells are only thought to play a limited role in CD4+ T cell activation since BCRs are clonotypically expressed. Here we show, however, that activated B cells can, both in vitro and in vivo, rapidly donate their BCR to bystander B cells, a process that is mediated by direct membrane transfer between adjacent B cells and is amplified by the interaction of the BCR with specific antigen. This results in a dramatic expansion in the number of antigen-binding B cells in vivo, with the transferred BCR endowing recipient B cells with the ability to present specific antigen to antigen-specific CD4+ T cells
THE PSOCOPTERA OF THE KRAKATAU ISLANDS, INDONESIA
At least 80 species of Psocoptera are represented in recent collections from the Krakatau Islands, Sunda Strait. They represent 15 families, and 29 species are described tu new. Twenty four species are known only from the Krahataus but. others are widespread in nearby regions of Sumatra and Java and a few are known to be more broadly distributed. Numbers of species recorded from each of the Krahatau Islands are : Rakata 58, Panjang 48, Sertung 27, Anak Krakatau 27
Variable iron-line emission near the black hole of Markarian 766
We investigate the link between ionised Fe X-ray line emission and continuum
emission in the bright nearby AGN, Mrk 766. A new long (433 ks) XMM-Newton
observation is analysed, together with archival data from 2000 and 2001. The
contribution from ionised line emission is measured and its time variations on
short (5-20 ks) timescales are correlated with the continuum emission. The
ionised line flux is found to be highly variable and to be strongly correlated
with the continuum flux, demonstrating an origin for the ionised line emission
that is co-located with the continuum emission. Most likely the emission is
ionised reflection from the accretion disc within a few A.U. of the central
black hole, and its detection marks the first time that such an origin has been
identified other than by fitting to spectral line profiles. Future observations
may be able to measure a time lag and hence achieve reverberation mapping of
AGN at X-ray energies.Comment: Accepted for publication, Astronomy and Astrophysics letter
Long-Term X-ray Spectral Variability in Seyfert 1 Galaxies
Direct time-resolved spectral fitting has been performed on continuous RXTE
monitoring of seven Seyfert 1 galaxies in order to study their broadband
spectral variability and Fe K alpha variability characteristics on time scales
of days to years. Variability in the Fe K alpha line is not detected in some
objects but is present in others, e.g., in NGC 3516, NGC 4151 and NGC 5548
there are systematic decreases in line flux by factors of ~2-5 over 3-4 years.
The Fe K alpha line varies less strongly than the broadband continuum, but,
like the continuum, exhibits stronger variability towards longer time scales.
Relatively less model-dependent broadband fractional variability amplitude
(Fvar) spectra also show weaker line variability compared to the continuum
variability. Comparable systematic long-term decreases in the line and
continuum are present in NGC 5548. Overall, however, there is no evidence for
correlated variability between the line and continuum, severely challenging
models in which the line tracks continuum variations modified only by a
light-travel time delay. Local effects such as the formation of an ionized skin
at the site of line emission may be relevant. The spectral fitting and Fvar
spectra both support spectral softening as continuum flux increases.Comment: Accepted for publication in ApJ. 29 page
A 100ks XMM-Newton view of the Seyfert 1.8 ESO113-G010. I. Discovery of large X-ray variability and study of the FeKalpha line complex
(Abridged) We present here a long (100ks) XMM-Newton follow-up of the Seyfert
1.8 galaxy ESO113-G010 performed in November 2005, in order to study over a
longer time-scale its main X-ray properties. The source was found in a
higher/softer time-averaged flux state, and timing analysis of this source
reveals strong, rapid variability. The Power Spectral Density (PSD) analysis
indicates (at 95% c.l.) a break at 3.7 x 10^-4 Hz. This cut-off frequency is
comparable to those measured in some other rapidly-variable Seyferts, such as
MCG-6-30-15 and NGC4051. From the mass-luminosity-time-scale, we infer that
M_BH ranges from 4 x 10^6 - 10^7 M_odot and the source is accreting at or close
to the Eddington rate (or even higher). The existing data cannot distinguish
between spectral pivoting of the continuum and a two-component origin for the
spectral softening, primarily because the data do not span a broad enough flux
range. In the case of the two-component model, the fractional offsets measured
in the flux-flux plots increase significantly toward higher energies (similar
to what is observed in MCG-6-30-15) as expected if there exists a constant
reflection component. Contrary to May 2001, no significant highly redshifted
emission line is observed (which might be related to the source flux level),
while two narrow emission lines at about 6.5keV and 7keV are observed. The S/N
is not high enough to establish if the lines are variable or constant. As
already suggested by the 2001 observation, no significant constant narrow
6.4keV FeK line (EW~32eV) is observed, hence excluding any dominant emission
from distant cold matter such as a torus in this Seyfert type 1.8 galaxy.Comment: Accepted for publication in A&A, 10 pages, 11 figures, 2 table
X-ray Fluctuation Power Spectral Densities of Seyfert 1 Galaxies
By combining complementary monitoring observations spanning long, medium and
short time scales, we have constructed power spectral densities (PSDs) of six
Seyfert~1 galaxies. These PSDs span 4 orders of magnitude in temporal
frequency, sampling variations on time scales ranging from tens of minutes to
over a year. In at least four cases, the PSD shows a "break," a significant
departure from a power law, typically on time scales of order a few days. This
is similar to the behavior of Galactic X-ray binaries (XRBs), lower mass
compact systems with breaks on time scales of seconds. NGC 3783 shows tentative
evidence for a doubly-broken power law, a feature that until now has only been
seen in the (much better-defined) PSDs of low-state XRBs. It is also
interesting that (when one previously-observed object is added to make a small
sample of seven), an apparently significant correlation is seen between the
break time scale and the putative black hole mass , while none
is seen between break time scale and luminosity. The data are consistent with
the linear relation T = M_{\rm BH}/10^{6.5} \Msun; extrapolation over 6--7
orders of magnitude is in reasonable agreement with XRBs. All of this
strengthens the case for a physical similarity between Seyfert~1s and XRBs.Comment: 27 pages, 13 figures. Accepted for publication in ApJ. Typo correcte
Evidence for Rapid Iron K_alpha Line Flux Variability in MCG--6-30-15
This paper employs direct spectral fitting of individual orbital data in
order to measure rapid X-ray iron K_alpha line and continuum spectral slope
variations in Seyfert 1 galaxies with unprecedented temporal resolution.
Application of this technique to a long RXTE observation of MCG--6-30-15
indicates that the line flux does vary on short (~1d) timescales, but that
these variations are not correlated with changes in the continuum flux or
slope. These rapid variations indicate that the line does indeed originate
close to the black hole, confirming predictions based on its very broad
profile. However, the lack of a correlation with the continuum presents
problems for models in which the line variations are driven by those in the
continuum, modified only by light-travel time effects. Instead, it may be that
the line responds according to a physical process with a different time scale,
such as ionization instabilities in the disk, or perhaps that the geometry and
physical picture is more complex than implied by the simplest disk-corona
models.
These data also indicate that the slope of the underlying power-law continuum
(Gamma) shows strong variability and is tightly correlated with the continuum
flux in the sense that the spectrum steepens as the source brightens. All of
these results have been checked with extensive simulations, which also
indicated that a spurious correlation between Gamma and Compton reflection
fraction (R) will result if these quantities are measured from the same
spectra. This casts serious doubts on previous claims of such a Gamma-R
correlation.Comment: Accepted for publication in Ap
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