Physical education as a means of biopower in inter-war Malta

This article investigates Michael Foucault’s concept of biopower and its prevalence with-in the Maltese education system during the inter-war period. The study of primary sources shows biopower to have increased in the inter-war years, most notably through the development of physical education. Physical Education or P.E., as it was called at the time, became a tool for the promotion of the colonial ideal of being British. As a result, biopower became a distinctive marker of gender identity, particularly for males. Imperialism was equated with the development of a muscular model for the Maltese boys. Overall, however, this model of masculinity remained relatively weak as Malta lacked the infrastructure and resources needed for a state’s use of biopower.peer-reviewe

A quality of life measure for limb lymphoedema (LYMQOL)

Background: This paper describes the validation of a 'condition-specific' quality of life (QoL) assessment tool for lymphoedema of the limbs (LYMQOL). Aims: To ascertain whether the tool could accurately assess QoL in this patient group. Methods: Face and content validity were assessed by patient questionnaires; criterion validity by comparison with European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire - Core 30 questions (EORTC QLQ-C30); internal validity by Cronbach's Alpha and split half-testing of each domain; reliability by the test-retest method; construct validity by comparing LYMQOL score with initial limb volume and responsiveness by measuring changes in score following treatment. Results: The tool was validated in a total of 209 patients. Face, content, criterion and interval validity were supported. However, there was no correlation between initial limb volume and LYMQOL score (construct validity), a finding which is similar to that from other studies. The validation of responsiveness was limited by the small numbers of responses at three and six months after the initial assessment. Conclusions: LYMQOL is a validated condition-specific QoL assessment tool which can be used for lymphoedema of the limbs both in clinical assessment and as an outcome measure

Extent of sleep problems and relationship with severity of chronic pain using three validated sleep assessment tools

Open access via Sage agreementPeer reviewedPostprin

Biomarkers of Lung Epithelial Damage After Inhalation Injury

Burn and inhalation injury affects almost half a million people in the United States each year and it is one of the most complicated forms of trauma to treat. Further research is needed in order to better understand the precise mechanisms behind both burn and inhalational injury, as well as means by which to more accurately stratify patients by injury severity in order to care for them more effectively. In this study, I examine two potential biomarkers in mice with possible translational relevance that could be of use in quantifying injury severity in hospitalized patients. IL-33 and 8-isoprostane may be indicators of acute and long-term damage, respectively. IL-33 is elevated at twenty-four hours post-injury in mice with inhalation injury, while 8-isoprostane is elevated in mice with combined burn + inhalation injury at two weeks post-injury. These data may begin to provide a method for better patient evaluation and improved outcome.Master of Scienc

The experience of non-epileptic attack disorder (NEAD) : a repertory grid study examining NEAD patients' construal of their disorder

Non-epileptic attack disorder (NEAD) is a disorder resembling epilepsy, but is caused by psychological processes rather than neurological disturbance. Approximately 15-30% of patients referred to specialist epilepsy centres have NEAD as opposed to epilepsy. Research into NEAD has largely focused on the differential diagnosis of NEAD and identifying risk factors, such as abuse and psychopathology. Whilst this is important, there remains a paucity of research exploring the processes involved in the development and maintenance of NEAD, which contributes to the lack of research investigating treatment effectiveness and prognosis. Furthermore, there remains a paucity of research investigating patient perceptions and experiences, despite such factors influencing prognosis. Subsequently, the current study used repertory grid methodology to explore the largely overlooked domain of how individuals with NEAD construe their world (i.e. how they perceive themselves, others and their disorder). Twelve individuals with a diagnosis of NEAD were recruited from a clinical neuropsychology department within North-West England. This study was an exploratory, cross-sectional study using the repertory grid technique to explore the participants' construals of themselves and others, including construals of their ideal self and self before NEAD. Based on personal construct theory, this method aimed to overcome some of the methodological limitations inherent within NEAD research, by minimising researcher bias, exploring implicit and explicit perceptions and exploring both individual and group perceptions.A case series of grids was presented. Individual and multiple analyses were used to explore participants' construct systems. A data driven approach enabled hypotheses to be developed from the individual grids, which were explored via a composite grid and SocioNet analysis. Despite some themes being identified, the findings revealed the uniqueness of the participants' ways of construing, including a lack of shared understanding amongst the participants. The participants were unhappy with their current self and no longer construed themselves to be the person they were before the onset of NEAD. They also construed themselves as being distinct and/or alienated from others, although some participants construed positive consequences as a result of their NEAD. Whilst most participants agreed with their NEAD diagnosis 'label', they were less accepting of the psychological factors that characterise the diagnosis. Finally, physical health difficulties were construed as being preferable to experiencing mental health difficulties. The findings were discussed in relation to previous research and theoretical implications were highlighted. Clinical implications were highlighted, particularly how the current diagnostic and treatment system for individuals with NEAD may threaten their self-identity. Methodological considerations and recommendations for future research were also suggested. The repertory grid technique was found to be a useful and effective method to investigate the subjective perceptions of individuals with NEAD.EThOS - Electronic Theses Online ServiceLisa MacRae, 3.53 Simon Building, The University of Manchester, Brunswick Street, Manchester, M13 9PLGBUnited Kingdo

The Possibilities and Limitations of Private Prediction Markets

We consider the design of private prediction markets, financial markets designed to elicit predictions about uncertain events without revealing too much information about market participants' actions or beliefs. Our goal is to design market mechanisms in which participants' trades or wagers influence the market's behavior in a way that leads to accurate predictions, yet no single participant has too much influence over what others are able to observe. We study the possibilities and limitations of such mechanisms using tools from differential privacy. We begin by designing a private one-shot wagering mechanism in which bettors specify a belief about the likelihood of a future event and a corresponding monetary wager. Wagers are redistributed among bettors in a way that more highly rewards those with accurate predictions. We provide a class of wagering mechanisms that are guaranteed to satisfy truthfulness, budget balance on expectation, and other desirable properties while additionally guaranteeing epsilon-joint differential privacy in the bettors' reported beliefs, and analyze the trade-off between the achievable level of privacy and the sensitivity of a bettor's payment to her own report. We then ask whether it is possible to obtain privacy in dynamic prediction markets, focusing our attention on the popular cost-function framework in which securities with payments linked to future events are bought and sold by an automated market maker. We show that under general conditions, it is impossible for such a market maker to simultaneously achieve bounded worst-case loss and epsilon-differential privacy without allowing the privacy guarantee to degrade extremely quickly as the number of trades grows, making such markets impractical in settings in which privacy is valued. We conclude by suggesting several avenues for potentially circumventing this lower bound

A Systematic Review of Studies Describing the Effectiveness, Acceptability, and Potential Harms of Place-Based Interventions to Address Loneliness and Mental Health Problems

Given the links between the built environment and loneliness, there is interest in using place-based approaches (addressing built environment characteristics and related socio-spatial factors) in local communities to tackle loneliness and mental health problems. However, few studies have described the effectiveness, acceptability, or potential harms of such interventions. This review aimed to synthesize the literature describing local community-based interventions that target place-based factors to address loneliness and mental health problems, informing the development of future public health approaches. We searched PsycINFO, Medline, and Embase using a structured search strategy to identify English-language studies evaluating the effectiveness, acceptability, and potential harms of place-based community interventions in addressing loneliness and mental health problems, both in general and clinical populations. Seven studies met the inclusion criteria, classified as evaluating provision of community facilities (such as clubhouses), active engagement in local green spaces, and housing regeneration. None were randomised trials. Quantitative and qualitative findings suggested promising effects and/or acceptability of six interventions, with minimal potential harms. There is a clear need for randomised trials or quasi-experimental studies of place-based interventions to describe their effectiveness in addressing loneliness and mental health problems, as well as complementary qualitative work investigating acceptability. This will inform future policy development

Development of the research lifecycle model for library services

Can the niche services of individual librarians across multiple libraries be developed into a suite of standard services available to all scientists that support the entire research lifecycle

Phenotypic plasticity in normal breast derived epithelial cells

Background Normal, healthy human breast tissue from a variety of volunteer donors has become available for research thanks to the establishment of the Susan G. Komen for the Cure® Tissue Bank at the IU Simon Cancer Center (KTB). Multiple epithelial (K-HME) and stromal cells (K-HMS) were established from the donated tissue. Explant culture was utilized to isolate the cells from pieces of breast tissue. Selective media and trypsinization were employed to select either epithelial cells or stromal cells. The primary, non-transformed epithelial cells, the focus of this study, were characterized by immunohistochemistry, flow cytometry, and in vitro cell culture. Results All of the primary, non-transformed epithelial cells tested have the ability to differentiate in vitro into a variety of cell types when plated in or on biologic matrices. Cells identified include stratified squamous epithelial, osteoclasts, chondrocytes, adipocytes, neural progenitors/neurons, immature muscle and melanocytes. The cells also express markers of embryonic stem cells. Conclusions The cell culture conditions employed select an epithelial cell that is pluri/multipotent. The plasticity of the epithelial cells developed mimics that seen in metaplastic carcinoma of the breast (MCB), a subtype of triple negative breast cancer; and may provide clues to the origin of this particularly aggressive type of breast cancer. The KTB is a unique biorepository, and the normal breast epithelial cells isolated from donated tissue have significant potential as new research tools