266 research outputs found
Building sustainable communities
Local Initiatives Support Corporation and two nonprofits are launching a new concept in Rhode Island. Through its Sustainable Communities program, LISC will assist the organizations in conducting resident-led planning to ensure buy-in for improvements in targeted neighborhoods.Community development - Rhode Island
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An ES Cell System for Rapid, Spatial and Temporal Analysis of Gene Function in vitro and in vivo
We describe a versatile genetic system for rapid analysis of mammalian gene function. In this, loss of reporter activity in a novel embryonic stem (ES) cell line enables rapid identification of targeting to the ubiquitously expressed Rosa26 locus. Subsequent regulation of gene activity is governed by a dual regulatory strategy utilizing two drugs, Tamoxifen and Doxycycline. To illustrate this approach, a dominant allele of Smoothened was introduced into this cell line, enabling regulated activation of Hedgehog signaling. By coupling Cre-loxP dependent activation with tetracycline dependent transcription in a single allele, we established a conditional method to control Smoothened activity and neural progenitor specification in differentiating ES cells in vitro and in chimeric embryos in vivo When crossed to an appropriate Cre driver strain, gene activity can also be temporally regulated within a specific cell lineage. This platform will facilitate rapid analysis of gene function in the mouse.Molecular and Cellular BiologyStem Cell and Regenerative Biolog
Prospectus, September 24, 1980
RODNEY DANGERFIELD GETS SOME RESPECT FROM PC; PCF group greets newcomers; Parkland offers COSMOS telecourse; Clerks to be on campus to register voters; Women\u27s Program discusses importance of adequate diet; Breakdown of budget: Where does all your money go?; Women\u27s Program presents last of self-care series; Parkland College Board of Trustees meets; Members needed; A friend is someone who...; Family Life Program offers Living in Step ; Chimera Inc. offers workshop; PACT presents seminar for expectant parents; Steve Goodman: A talented performer; The Ducks have a good time; Rodney Dangerfield: I don\u27t get no respect; He will always get respect in Champaign-Urbana ; Francis named Outstanding Young Men of America ; Eisner to hold celebration; Classifieds; Showcase and workshop Oct. 8; PACT presents program: Early childhood; Volleyballers win two; Upsets spoil Fast Freddy; All you lost freshman-- pay attention to this story; Fast Freddy Contesthttps://spark.parkland.edu/prospectus_1980/1020/thumbnail.jp
Human imprinted chromosomal regions are historical hot-spots of recombination.
Human recombination rates vary along the chromosomes as well as between the two sexes. There is growing evidence that epigenetic factors may have an important influence on recombination rates, as well as on crossover position. Using both public database analysis and wet-bench approaches, we revisited the relationship between increased rates of meiotic recombination and genome imprinting. We constructed metric linkage disequilibrium (LD) maps for all human chromosomal regions known to contain one or more imprinted genes. We show that imprinted regions contain significantly more LD units (LDU) and have significantly more haplotype blocks of smaller sizes than flanking nonimprinted regions. There is also an excess of hot-spots of recombination at imprinted regions, and this is likely to do with the presence of imprinted genes, per se. These findings indicate that imprinted chromosomal regions are historical "hot-spots" of recombination. We also demonstrate, by direct segregation analysis at the 11p15.5 imprinted region, that there is remarkable agreement between sites of meiotic recombination and steps in LD maps. Although the increase in LDU/Megabase at imprinted regions is not associated with any significant enrichment for any particular sequence class, major sequence determinants of recombination rates seem to differ between imprinted and control regions. Interestingly, fine-mapping of recombination events within the most male meiosis-specific recombination hot-spot of Chromosome 11p15.5 indicates that many events may occur within or directly adjacent to regions that are differentially methylated in somatic cells. Taken together, these findings support the involvement of a combination of specific DNA sequences and epigenetic factors as major determinants of hot-spots of recombination at imprinted chromosomal regions
Prospectus, April 30, 1980
STUDENT GOV\u27T ELECTIONS TODAY, TOMORROW; Week in Review: World, Nation; Skyrocket interest rates force insurance borrowing; PC student heads to DC; Parkland Teacher Aide Program hosts Recognition Banquet Wed.; Illinois future can be as bright as ever; Arbor Day celebrated last Friday; Dental students to be capped; Males can survive; Women\u27s Program offers workshops; Community colleges can contribute; Open house of woods; Westerners celebrate different May Day; StuGo sponsors spring activities featuring balloons, kites, jazz; Letters to the Editor: Philemon lauded, Faculty thieves; One parent families are discussed; Cheap trick...; and Ted Nugent rock Assembly Hall; Classifieds; Dates to live by; Sports in Review: Baseball, Basketball, Hockey; Garden workshop concludes; Journ instructor gets textbook published; Forum presented Wed.; Track ready for state; Umpires clinic scheduled; Lucy coin sends Cobras to state; Cobras rounding out for sectional; New track gets workout; Parkland Baseball Statisticshttps://spark.parkland.edu/prospectus_1980/1028/thumbnail.jp
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1954 Turf Conference
Attendance (I - XV) Grass Leaves at Work - S.N. Postlethwait (5) Seed Supply and Prices - Gager T. Vaughn (8) Hocus-Pocus in Grass Breeding - Glen W. Burton (11) Techniques and Turf Quality - Fred V. Grau Case Histories of Turf Improvement Programs - O.J. Noer (20) Fertilizer Facts and Fancies - A.J. Ohlrogge (38) Crabgrass Control in Turf - Ralph E. Engel (43) Athletic Field Reseeding - Fred V. Grau (44) Vegetative Grass Potential - W.H. Daniel (48) Who Plays Golf Today? - Herb Graffis (50) Poa Annua & Arsenic Toxicity - W.H. Daniel (53) Replanting Golf Greens - (58) Planting Stolons on Large Areas - A. Linkogel (59) Management, Weather & Disease - Ralph Engel (62) Practical Microscopic Disease Observations - Robert Williams (64
野生ダイズ, 栽培ダイズおよび両種の自然交雑集団の探索, 収集とモニタリング : 秋田県, 茨城県, 高知県, 佐賀県における現地調査から
During 2003 and 2004, a total of 11 individuals of hybrid derivatives between wild and cultivated soybean were found at Akita (1 individual from one site) and Saga (8, 1 and 1 individuals from three sites). The aim of the present survey was to monitor and explore for hybrid derivatives at prefectures of Akita, Ibaraki, Kochi and Saga. In 2005, only one hybrid individual was found in a site at Saga, and no hybrid derivatives were newly found among 39 sites of wild soybean populations, including 14 sites, which were adjacent to soybean field the previous year. These results suggest that 1) pollen flow from soybean to wild soybean is a rare event, and 2) hybrid derivatives are subject to natural selection and obvious hybrid plants are transient in natural habitats
CALIOP Version 3 Data Products: A Comparison to Version 2
After launch we discovered that the CALIOP daytime measurements were subject to thermally induced beamdrift,and this caused the calibration to vary by as much as 30% during the course of a single daytime orbit segment. Using an algorithm developed by Powell et al.(2010), empirically derived correction factors are now computed in near realtime as a function of orbit elapsed time, and these are used to compensate for the beam wandering effects
Sources of non-methane hydrocarbons in surface air in Delhi, India
Rapid economic growth and development have exacerbated air quality problems across India, driven by many poorly understood pollution sources and understanding their relative importance remains critical to characterising the key drivers of air pollution. A comprehensive suite of measurements of 90 non-methane hydrocarbons (NMHCs) (C2–C14), including 12 speciated monoterpenes and higher molecular weight monoaromatics, were made at an urban site in Old Delhi during the pre-monsoon (28-May to 05-Jun 2018) and post-monsoon (11 to 27-Oct 2018) seasons using dual-channel gas chromatography (DC-GC-FID) and two-dimensional gas chromatography (GC×GC-FID). Significantly higher mixing ratios of NMHCs were measured during the post-monsoon campaign, with a mean night-time enhancement of around 6. Like with NOx and CO, strong diurnal profiles were observed for all NMHCs, except isoprene, with very high NMHC mixing ratios between 35–1485 ppbv. The sum of mixing ratios of benzene, toluene, ethylbenzene and xylenes (BTEX) routinely exceeded 100 ppbv at night during the post-monsoon period, with a maximum measured mixing ratio of monoaromatic species of 370 ppbv. The mixing ratio of highly reactive monoterpenes peaked at around 6 ppbv in the post-monsoon campaign and correlated strongly with anthropogenic NMHCs, suggesting a strong non-biogenic source in Delhi. A detailed source apportionment study was conducted which included regression analysis to CO, acetylene and other NMHCs, hierarchical cluster analysis, EPA UNMIX 6.0, principal component analysis/absolute principal component scores (PCA/APCS) and comparison with NMHC ratios (benzene/toluene and i-/n-pentane) in ambient samples to liquid and solid fuels. These analyses suggested the primary source of anthropogenic NMHCs in Delhi was from traffic emissions (petrol and diesel), with average mixing ratio contributions from Unmix and PCA/APCS models of 38% from petrol, 14% from diesel and 32% from liquified petroleum gas (LPG) with a smaller contribution (16%) from solid fuel combustion. Detailed consideration of the underlying meteorology during the campaigns showed that the extreme night-time mixing ratios of NMHCs during the post-monsoon campaign were the result of emissions into a very shallow and stagnant boundary layer. The results of this study suggest that despite widespread open burning in India, traffic-related petrol and diesel emissions remain the key drivers of gas-phase urban air pollution in Delhi
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Measurements of traffic-dominated pollutant emissions in a Chinese megacity
Direct measurements of NOx, CO and aromatic volatile organic compound (VOC) (benzene, toluene, C2-benzenes and C3-benzenes) flux were made for a central area of Beijing using the eddy-covariance technique. Measurements were made during two intensive field campaigns in central Beijing as part of the Air Pollution and Human Health (APHH) project, the first in November–December 2016 and the second during May–June 2017, to contrast wintertime and summertime emission rates. There was little difference in the magnitude of NOx flux between the two seasons (mean NOx flux was 4.41 mg m−2 h−1 in the winter compared to 3.55 mg m−2 h−1in the summer). CO showed greater seasonal variation, with mean CO flux in the winter campaign (34.7 mg m−2 h−1) being over twice that of the summer campaign (15.2 mg m−2 h−1). Larger emissions of aromatic VOCs in summer were attributed to increased evaporation due to higher temperatures. The largest fluxes in NOx and CO generally occurred during the morning and evening rush hour periods, indicating a major traffic source with high midday emissions of CO, indicating an additional influence from cooking fuel. Measured NOx and CO fluxes were then compared to the MEIC 2013 emissions inventory, which was found to significantly overestimate emissions for this region,providing evidence that proxy-based emissions inventories have positive biases in urban centres. This first set of pollutant fluxes measured in Beijing provides an important benchmark of emissions from the city which can help to inform and evaluate current emissions inventories
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