506 research outputs found
Inflations of Geometric Grid Classes: Three Case Studies
We enumerate three specific permutation classes defined by two forbidden
patterns of length four. The techniques involve inflations of geometric grid
classes
Subclasses of the separable permutations
We prove that all subclasses of the separable permutations not containing
Av(231) or a symmetry of this class have rational generating functions. Our
principal tools are partial well-order, atomicity, and the theory of strongly
rational permutation classes introduced here for the first time
Generating Permutations with Restricted Containers
We investigate a generalization of stacks that we call
-machines. We show how this viewpoint rapidly leads to functional
equations for the classes of permutations that -machines generate,
and how these systems of functional equations can frequently be solved by
either the kernel method or, much more easily, by guessing and checking.
General results about the rationality, algebraicity, and the existence of
Wilfian formulas for some classes generated by -machines are
given. We also draw attention to some relatively small permutation classes
which, although we can generate thousands of terms of their enumerations, seem
to not have D-finite generating functions
A three dimensional model of the photosynthetic membranes of Ectothiorhodospira halochloris
The three dimensional organization of the complete photosynthetic apparatus of the extremely halophilic, bacteriochlorophyll b containing Ectothiorhodospira halochloris has been elaborated by several techniques of electron microscopy. Essentially all thylakoidal sacs are disc shaped and connected to the cytoplasmic membrane by small membraneous ldquobridgesrdquo. In sum, the lumina of all thylakoids (intrathylakoidal space) form one common periplasmic space. Thin sections confirm a paracrystalline arrangement of the photosynthetic complexes in situ. The ontogenic development of the photosynthetic apparatus is discussed based on a structural model derived from serial thin sections
Functional Analyses of the Three Simian Hemorrhagic Fever Virus Nonstructural Protein 1 Papain-Like Proteases
The N-terminal region of simian hemorrhagic fever virus (SHFV) nonstructural polyprotein 1a is predicted to encode three papain-like proteases (PLP1α, PLP1β, and PLP1γ). Catalytic residues and cleavage sites for each of the SHFV PLP1s were predicted by alignment of the SHFV PLP1 region sequences with each other as well as with those of other arteriviruses, and the predicted catalytic residues were shown to be proximal by homology modeling of the SHFV nsp1s on porcine respiratory and reproductive syndrome virus (PRRSV) nsp1 crystal structures. The functionality of the predicted catalytic Cys residues and cleavage sites was tested by analysis of the autoproteolytic products generated in in vitro transcription/translation reactions done with wild-type or mutant SHFV nsp1 constructs. Cleavage sites were also analyzed by mass spectroscopy analysis of selected immunoprecipitated cleavage products. The data showed that each of the three SHFV PLP1s is an active protease. Cys63 was identified as the catalytic Cys of SHFV PLP1α and is adjacent to an Ala instead of the canonical Tyr observed in other arterivirus PLP1s. SHFV PLP1γ is able to cleave at both downstream and upstream nsp1 junction sites. Although intermediate precursor polyproteins as well as alternative products generated by each of the SHFV PLP1s cleaving at sites within the N-terminal region of nsp1β were produced in the in vitro reactions, Western blotting of SHFV-infected, MA104 cell lysates with SHFV nsp1 protein-specific antibodies detected only the three mature nsp1 proteins
Eating disorder outcomes : findings from a rapid review of over a decade of research
Background Eating disorders (ED), especially Anorexia Nervosa (AN), are internationally reported to have amongst the highest mortality and suicide rates in mental health. With limited evidence for current pharmacological and/or
psychological treatments, there is a grave responsibility within health research to better understand outcomes for people with a lived experience of ED, factors and interventions that may reduce the detrimental impact of illness and
to optimise recovery. This paper aims to synthesise the literature on outcomes for people with ED, including rates of remission, recovery and relapse, diagnostic crossover, and mortality. Methods This paper forms part of a Rapid Review series scoping the evidence for the field of ED, conducted to inform the Australian National Eating Disorders Research and Translation Strategy 2021–2031, funded and released by the Australian Government. ScienceDirect, PubMed and Ovid/MEDLINE were searched for studies published between 2009 and 2022 in English. High-level evidence such as meta-analyses, large population studies and Randomised Controlled Trials were prioritised through purposive sampling. Data from selected studies relating to outcomes for people with ED were synthesised and are disseminated in the current review. Results Of the over 1320 studies included in the Rapid Review, the proportion of articles focused on outcomes in ED was relatively small, under 9%. Most evidence was focused on the diagnostic categories of AN, Bulimia Nervosa and Binge Eating Disorder, with limited outcome studies in other ED diagnostic groups. Factors such as age at presentation, gender, quality of life, the presence of co-occurring psychiatric and/or medical conditions, engagement in treatment and access to relapse prevention programs were associated with outcomes across diagnoses, including
mortality rates. Conclusion Results are difficult to interpret due to inconsistent study definitions of remission, recovery and relapse, lack of longer-term follow-up and the potential for diagnostic crossover. Overall, there is evidence of low rates of remission and high risk of mortality, despite evidence-based treatments, especially for AN. It is strongly recommended
that research in long-term outcomes, and the factors that influence better outcomes, using more consistent variables and methodologies, is prioritised for people with ED
Forces Sauces and Eggs for Soldiers: food, nostalgia, and the rehabilitation of the British military
This article identifies, and considers the political implications of, the association of the contemporary British military and British soldiers with nostalgia. This aspect of the discursive project of rehabilitating the British military post-Iraq has not hitherto been theorized. The article analyses a set of exemplifying texts, four military charity food brands (Eggs for Soldiers, Forces Sauces, Red Lion Foods, and Rare Tea Company Battle of Britain Tea) to ask how nostalgic rehabilitation of the British military unfolds at the intersections of militarization, commemoration, and post-2008 “conscience capitalism”. I outline how military charity food brands are a form of “conscience capitalism” through which the perpetuation of militarized logics are produced as a notionally apolitical social “cause”, rendered intelligible within the terms of existing commoditized discourses of post-2008 vintage nostalgia. I then ask what understandings of British soldiers and the British military are constituted within the discourse of nostalgic rehabilitation, and secondly what forms of commemoration are entailed. I argue that a nostalgic generalization of soldiers and the military nullifies the potential unruliness of individual soldiers and obscures the specifics of recent, controversial, wars. Secondly nostalgic civil–military engagement entails a commemorative logic in which forms of quasi-military service are brought into the most banal spaces of everyday civilian life
Patterns of democracy: Coalition governance and majoritarian modification in the United Kingdom, 2010–2015
The UK is often regarded as the archetype of Westminster democracy and as the empirical
antithesis of the power-sharing coalitions of Western Europe. Yet, in recent years a different
account has emerged that focuses on the subtler institutional dynamics which limit the
executive. It is to this body of scholarship that this article responds, locating the recent
chapter of coalition government within the wider context of the UK’s democratic evolution.
To do so, the article draws Lijphart’s two-dimensional typology of democracies, developing a
refined framework that enables systematic comparison over time. The article demonstrates
that between over the course of the 2010-15 Parliament, the UK underwent another period of
majoritarian modification, driven by factors including the long-term influence of the
constitutional forces unleashed under Labour and the short-term impact of coalition
management. The article makes several important contributions, salient in the UK and
beyond. Theoretically, it offers a critical rejoinder to debates regarding the relationship
between institutional design and democratic performance. Methodologically, it demonstrates
that the tools of large-scale comparison can be effectively scaled-down to facilitate withincase
analysis. Empirically, it provides a series of conclusions regarding the tenability of the
UK’s extant democratic architecture under the weight of pressures to which it continues to be
subject
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