Petrogenesis of the early Cretaceous intra-plate basalts from the western North China Craton: Implications for the origin of the metasomatized cratonic lithospheric mantle

We present new bulk-rock 40Ar/39Ar age, major and trace elements and Sr-Nd-Hf isotopic data on the early Cretaceous intra-plate alkali basalts from the Western North China Craton (WNCC) to study the origin of the metasomatized cratonic lithosphere mantle. The age of these basalts is ~116 Ma. These basalts have elevated incompatible element abundance with high [La/Sm]N (2.80–4.56) and enriched Sr-Nd-Hf isotopic compositions (87Sr/86Sri = 0.7062–0.7075, εNd(t) = −6.0 to −13.0 and εHf(t) = −8.3 to −17.4), being similar to the contemporary analogues from the Western North China Craton and Paleozoic kimberlites and mantle xenoliths. The WNCC basalts also show good correlations between ɛNd(t) and ɛHf(t), and high [La/Sm]N. All these geochemical observations are consistent with the interpretation that these basalts originated from partial melting of the lithospheric mantle that experienced melt metasomatism. Two types metasomatism melts are required to explain the geochemical characteristics of these rocks. The obvious negative Nbsingle bondTa (compared with K)-Ti and positive Basingle bondPb anomalies observed in these basalts further constrain that one of the metasomatic melts was derived from the subducted terrigenous sediment. Furthermore, the overall higher P/Nd, Nb/La and Nb/Th and lower Lu/Hf of basalts in the WNCC suggest that there is also contribution of low-F melts from asthenosphere mantle. Collectively, we suggest that the formation of the metasomatized lithosphere mantle beneath the WNCC is the process of metasomatic reaction between mantle peridotite and the melts of different origin to generate metasomatic veins containing amphibole/phlogopite. Partial melting of the metasomatic lithospheric mantle at 106–120 Ma in the WNCC was considered to be induced by thermal perturbation that was ultimately related to the breakoff of the subducted oceanic slab following the closure of the Mongolia-Okhotsk ocean

VIM-1, VIM-34, and IMP-8 Carbapenemase-Producing Escherichia coli strains recovered from a Portuguese river

[No abstract available]This work was supported by the University of Fribourg

Detecting conflicts in legal systems

Abstract. When acting in different jurisdictions (e.g. under the laws of different countries) at the same time, it can be of great value for individuals to be able to determine whether disparities among the laws of these different systems exist and allowing them to identify the consequences that may follow from these dispari-ties. For individuals, it is typically not of interest to find all the ways in which these legal systems differ, but rather to establish whether a particular course of action may have different legal interpretations, depending on the jurisdiction. In this paper we present a formal and computational framework that, given specific scenarios (descriptions of courses of action), can automatically detect whether these scenarios could lead to different outcomes. We demonstrate our approach by means of a private international law case-study where a company drafts a con-tract clause after examining the consequences in the available jurisdictions.

A model for preservation of thymocyte-depleted thymus

DiGeorge syndrome is a disorder caused by a microdeletion on the long arm of chromosome 22. Approximately 1% of patients diagnosed with DiGeorge syndrome may have an absence of a functional thymus, which characterizes the complete form of the syndrome. These patients require urgent treatment to reconstitute T cell immunity. Thymus transplantation is a promising investigational procedure for reconstitution of thymic function in infants with congenital athymia. Here, we demonstrate a possible optimization of the preparation of thymus slices for transplantation through prior depletion of thymocytes and leukocyte cell lineages followed by cryopreservation with cryoprotective media (5% dextran FP 40, 5% Me2SO, and 5% FBS) while preserving tissue architecture. Thymus fragments were stored in liquid nitrogen at -196°C for 30 days or one year. The tissue architecture of the fragments was preserved, including the distinction between medullary thymic epithelial cells (TECs), cortical TECs, and Hassall bodies. Moreover, depleted thymus fragments cryopreserved for one year were recolonized by intrathymic injections of 3×106 thymocytes per mL, demonstrating the capability of these fragments to support T cell development. Thus, this technique opens up the possibility of freezing and storing large volumes of thymus tissue for immediate transplantation into patients with DiGeorge syndrome or atypical (Omenn-like) phenotype

Solid air hydrogen liquefaction, the missing link of the hydrogen economy

The most challenging aspect of developing a green hydrogen economy is long-distance oceanic transportation. Hydrogen liquefaction is a transportation alternative. However, the cost and energy consumption for liquefaction is currently prohibitively high, creating a major barrier to hydrogen supply chains. This paper proposes using solid nitrogen or oxygen as a medium for recycling cold energy across the hydrogen liquefaction supply chain. When a liquid hydrogen (LH2) carrier reaches its destination, the regasification process of the hydrogen produces solid nitrogen or oxygen. The solid nitrogen or oxygen is then transported in the LH2 carrier back to the hydrogen liquefaction facility and used to reduce the energy consumption cooling gaseous hydrogen. As a result, the energy required to liquefy hydrogen can be reduced by 25.4% using N2 and 27.3% using O2. Solid air hydrogen liquefaction (SAHL) can be the missing link for implementing a global hydrogen economy