605 research outputs found

    Efficient Fair Queueing using Deficit Round Robin

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    Fair queuing is a technique that allows each flow passing through a network device to have fair share of network resources. previous schemes for fair queuing that achieved nearly perfect fairness were expensive to implement: specifically, the work required to process a packet in these schemes was O(log(n)), where n is the number of active flows. This is expensive at high speeds. On the other hand, cheaper approximations of fair queuing that have been reported in the literature exhibit unfair behavior. In this paper, we describe a new approximation of fair queuing, that we call Deficit Round Robin. Our scheme achieves nearly perfect fairness in terms of throughput, requires only O(1) work to process a packet, and is simple enough to implement in hardware. Deficit Round Robin is also applicable to other scheduling problems where servicing cannot be broken up into smaller units

    Redesigning the BSD Callout and Timer Facilities

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    We describe a new implementation of the BSD callout and timer facilities. Current BSD kernels take time proportional to the number of outstanding timers to set or cancel timers. Our implementation takes constant time to start, stop, and maintain timers; this leads to a highly scalable design that can support thousands of outstanding timers without much overhead. Unlike the existing implementation, our routines are guaranteed to lock out interrupts only for a small, bounded amount of time. We also extend the setitimer() interface to allow a process to have multiple outstanding timers, thereby reducing the need for users to maintain their own timer packages. The changes to the BSD kernel are small (548 lines of code added, 80 removed) and are available on the World Wide Web

    Melioidosis in South Asia (India, Nepal, Pakistan, Bhutan and Afghanistan).

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    Despite the fact that South Asia is predicted to have the highest number of cases worldwide, melioidosis is a little-known entity in South Asian countries. It has never been heard of by the majority of doctors and has as yet failed to gain the attention of national Ministries of Health and country offices of the World Health Organization (WHO). Although a few centers are diagnosing increasing numbers of cases, and the mortality documented from these institutions is relatively high (nearly 20%), the true burden of the disease remains unknown. In India, most cases have been reported from southwestern coastal Karnataka and northeastern Tamil Nadu, although this probably simply reflects the presence of centers of excellence and researchers with an interest in the disease. As elsewhere, the majority of cases have type 2 diabetes mellitus and occupational exposure to the environment. Most present with community-acquired pneumonia and/or bacteremia, especially during heavy rainfall. The high seropositivity rate (29%) in Karnataka and isolation of B. pseudomallei from the environment in Tamil Nadu and Kerala confirm India as melioidosis-endemic, although the full extent of the distribution of the organism across the country is unknown. There are limited molecular epidemiological data, but, thus far, the majority of Indian isolates have appeared distinct from those from South East Asia and Australia. Among other South Asian countries, Sri Lanka and Bangladesh are known to be melioidosis-endemic, but there are no cases that have conclusively proved to have been acquired in Nepal, Bhutan, Afghanistan or Pakistan. There are no surveillance systems in place for melioidosis in South Asian countries. However, over the past two years, researchers at the Center for Emerging and Tropical Diseases of Kasturba Medical College, University of Manipal, have established the Indian Melioidosis Research Forum (IMRF), held the first South Asian Melioidosis Congress, and have been working to connect researchers, microbiologists and physicians in India and elsewhere in South Asia to raise awareness through training initiatives, the media, workshops, and conferences, with the hope that more patients with melioidosis will be diagnosed and treated appropriately. However, much more work needs to be done before we will know the true burden and distribution of melioidosis across South Asia

    Kondisi Sanitasi Terminal Mabu’un Kabupaten Tabalong

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    Abstract: Sanitary Conditions Terminal Mabu'un Tabalong. One impact of the terminal is the possibility of disease transfer and transmission of vector -borne diseases through the means of conveyance . This study aims to determine the sanitary conditions in the Terminal Mabu'un Tabalong . Data were collected in the form of frequency tabulation then analyzed descriptively and compared with the requirements according to DEPKES DITJEN . PPM and PLP 1999. The result show that the sanitation in Terminal Mabu'un Tabalong including healthy feasible for terminal infrastructure with a yield of 86.0 percent of ≤ 75 percent of the specified conditions. However there are several aspects that need attention sanitation ie from outside environmental health aspects, sanitation space and buildings , sanitary facilities and food sanitation . Efforts are being made to improve sanitation in Terminal Mabu'un Tabalong like doing cleaning around the terminal, power supply cleaning service for the reception area , increasing the number of bins, sanitary inspection terminals and provide counseling . Keywords : Health environment, sanitation value , sanitation termina

    Check list of fishes of the Gulf of Mannar ecosystem, Tamil Nadu, India

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    Gulf of Mannar Ecosystem (GOME) covers an area spread over Rameswaram and Kanyakumari for about 19000 km2 and lies between 78°11’E and 79°15’ E longitude and 8°49’N and 9°15’N latitude. The 21 coral islands form a network of habitats for different kinds of fishes and marine organisms. Fish samples were collected during April 2005 to March 2010 from different centers viz., Vembar, Tharuvaikulam, Vellapatti, Therespuram, Tuticorin, Alangarathattu, Pazhaykayal, Punnakayal, Kayalpattinam, Veerapandiapattinam, Thiruchendur and Manappad of Gulf of Mannar ecosystem. The present check list was the first attempt to produce a systematic list of fishes found in the Gulf of Mannar ecosystem. It includes 476 genera and 1182 species in 144 families and 39 orders, of which 628 species have been recorded in the present study

    Scrub typhus in South India: clinical and laboratory manifestations, genetic variability, and outcome

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    SummaryObjectivesThis study sought to document the clinical and laboratory manifestations, genetic variability, and outcomes of scrub typhus, an often severe infection caused by Orientia tsutsugamushi, in South India.MethodsPatients admitted to a large teaching hospital with IgM ELISA-confirmed scrub typhus were evaluated. Clinical examination with a thorough search for an eschar, laboratory testing, chest X-ray, and outcome were documented and analyzed. Additionally, a 410-bp region of the 56-kDa type-specific antigen gene of O. tsutsugamushi was sequenced and compared with isolates from other regions of Asia.ResultsMost of the 154 patients evaluated presented with fever and non-specific symptoms. An eschar was found in 86 (55%) patients. Mild hepatic involvement was seen in most, with other organ involvement including respiratory, cardiovascular, and renal. Multi-organ dysfunction was noted in 59 (38.3%), and the fatality rate was 7.8%. Hypotension requiring vasoactive agents was found to be an independent predictor of mortality (p<0.001). The phylogeny of 26 samples showed 17 (65%) clustering with the Kato-like group and eight (31%) with the Karp-like group.ConclusionsThe presentation of scrub typhus can be variable, often non-specific, but with potentially severe multi-organ dysfunction. Prompt recognition is key to specific treatment and good outcomes. Further study of the circulating strains is essential for the development of a successful vaccine and sensitive point-of-care testing

    Simultaneous solution of Kompaneets equation and Radiative Transfer equation in the photon energy range 1 - 125 KeV

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    Radiative transfer equation in plane parallel geometry and Kompaneets equation is solved simultaneously to obtain theoretical spectrum of 1-125 KeV photon energy range. Diffuse radiation field is calculated using time-independent radiative transfer equation in plane parallel geometry, which is developed using discrete space theory (DST) of radiative transfer in a homogeneous medium for different optical depths. We assumed free-free emission and absorption and emission due to electron gas to be operating in the medium. The three terms n,n2n, n^2 and (nxk)\displaystyle \bigg({\frac {\partial n}{\partial x_k}}\bigg) where nn is photon phase density and xk=(hνkTe)\displaystyle x_k= \bigg({\frac {h \nu} {k T_e}} \bigg) , in Kompaneets equation and those due to free-free emission are utilized to calculate the change in the photon phase density in a hot electron gas. Two types of incident radiation are considered: (1) isotropic radiation with the modified black body radiation IMBI^{MB} [1] and (2) anisotropic radiation which is angle dependent. The emergent radiation at τ=0\tau=0 and reflected radiation τ=τmax\tau=\tau_{max} are calculated by using the diffuse radiation from the medium. The emergent and reflected radiation contain the free-free emission and emission from the hot electron gas. Kompaneets equation gives the changes in photon phase densities in different types of media. Although the initial spectrum is angle dependent, the Kompaneets equation gives a spectrum which is angle independent after several Compton scattering times.Comment: 31 pages, 8 figures, Accepte

    Cervical Cancer Risk Factors among Female High School Students in Baguio city

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    Objective: To determine and correlate the prevalence of cervical cancer risk factor exposures such as smoking, sexual activity, use of condoms, contraceptives pills, and history of STIs according to age and high school year level in Baguio city high-school students, Philippines. Background: Cervical cancer is the second cause of cancer deaths among women in the Philippines and the second most frequent cancer in women ages 15-44 [1]. Methods: The risk stratification level of cervical cancer development was determined using a questionnaire adapted from Siteman Cancer Center and Barnes- Jewish Hospital and Washington University School of Medicine. A coding manual was created for each of the risk factors and the level stratification of the risk factors. The study size was computed with the use of Open Epi, Version 2, open source calculator—SSPropo, an internet based epidemiologic calculator. Results: 98.3% of the study group was classified to have much below average risk of developing cervical cancer. 1.2% of the study group was of below average risk and 0.5% of the study group was with above average risk of cervical cancer with significant relationship to age of first sexual contact and number of sexual partners. Conclusion: An increased risk of cervical cancer among these students were associated with early onset of sexual activity, increasing number of sexual partners and early parity

    Airway and Oral microbiome profiling of SARS-CoV-2 infected asthma and non-asthma cases revealing alterations-A pulmonary microbial investigation

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    New evidence strongly discloses the pathogenesis of host-associated microbiomes in respiratory diseases. The microbiome dysbiosis modulates the lung's behavior and deteriorates the respiratory system's effective functioning. Several exogenous and environmental factors influence the development of asthma and chronic lung disease. The relationship between asthma and microbes is reasonably understood and yet to be investigated for more substantiation. The comorbidities such as SARS-CoV-2 further exacerbate the health condition of the asthma-affected individuals. This study examines the raw 16S rRNA sequencing data collected from the saliva and nasopharyngeal regions of pre-existing asthma (23) and non-asthma patients (82) infected by SARS-CoV-2 acquired from the public database. The experiment is designed in a two-fold pattern, analyzing the associativity between the samples collected from the saliva and nasopharyngeal regions. Later, investigates the microbial pathogenesis, its role in exacerbations of respiratory disease, and deciphering the diagnostic biomarkers of the target condition. LEfSE analysis identified that Actinobacteriota and Pseudomonadota are enriched in the SARS-CoV-2-non-asthma group and SARS-CoV-2 asthma group of the salivary microbiome, respectively. Random forest algorithm is trained with amplicon sequence variants (ASVs) attained better classification accuracy, ROC scores on nasal (84% and 87%) and saliva datasets (93% and 97.5%). Rothia mucilaginosa is less abundant, and Corynebacterium tuberculostearicum showed higher abundance in the SARS-CoV-2 asthma group. The increase in Streptococcus at the genus level in the SARS-CoV-2-asthma group is evidence of discriminating the subgroups.Scopu
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