Measurements of Isospin Asymmetry and Difference of Direct CP Asymmetries in Inclusive B→Xsγ Decays

We report measurements of isospin asymmetry Delta(0-) and difference of direct CP asymmetries Delta A(CP) between charged and neutral B -> X-s gamma decays. This analysis is based on the data sample containing 772 x 10(6)B (B) over bar pairs that was collected with the Belle detector at the KEKB energy-asymmetric ethornecollider. Using a sum-of-exclusive technique with invariant X-s mass up to 2.8 GeV= c2, we obtain Delta(0-) = [0.48 +/- 1.49(stat) +/- 0.97(syst) +/- 1.15(f(+-)/f(00))]% and Delta A(CP) = [+3.69 +/- 2.65(stat) +/- 0.76(syst)]%, where the last uncertainty for.0-is due to the uncertainty on the production ratio of B+B- to B-0(B) over bar (0) in.o4Sthorn decays. The measured value of Delta(0-) is consistent with zero, allowing us to constrain the resolved photon contribution in the B -> X-s gamma, and improve the branching fraction prediction. The result for Delta A(CP) is consistent with the prediction of the SM. We also measure the direct CP asymmetries for charged and neutral B -> X-s gamma decays. All the measurements are the most precise to date.The authors would like to thank M. Misiak, G. Paz and M. Endo for fruitful discussions. A. I. is supported by the Japan Society for the Promotion of Science (JSPS) Grant No. 16H03968. We thank the KEKB group for the excellent operation of the accelerator; the KEK cryogenics group for the efficient operation of the solenoid; and the KEK computer group, the National Institute of Informatics, and the Pacific Northwest National Laboratory (PNNL) Environmental Molecular Sciences Laboratory (EMSL) computing group for valuable computing and Science Information NETwork 5 (SINET5) network support. We acknowledge support from the Ministry of Education, Culture, Sports, Science, and Technology (MEXT) of Japan, the Japan Society for the Promotion of Science (JSPS), and the Tau-Lepton Physics Research Center of Nagoya University; the Australian Research Council; Austrian Science Fund under Grant No. P 26794-N20; the National Natural Science Foundation of China under Contracts No. 11435013, No. 11475187, No. 11521505, No. 11575017, No. 11675166, No. 11705209; Key Research Programof Frontier Sciences, Chinese Academy of Sciences (CAS), Grant No. QYZDJ-SSW-SLH011; the CAS Center for Excellence in Particle Physics (CCEPP); Fudan University Grant No. JIH5913023, No. IDH5913011/003, No. JIH5913024, No. IDH5913011/002; the Ministry of Education, Youth and Sports of the Czech Republic under Contract No. LTT17020; the Carl Zeiss Foundation, the Deutsche Forschungsgemeinschaft, the Excellence Cluster Universe, and the VolkswagenStiftung; the Department of Science and Technology of India; the Istituto Nazionale di Fisica Nucleare of Italy; National Research Foundation (NRF) of Korea Grants No. 2014R1A2A2A01005286, No. 2015R1A2A2A01003280, No. 2015H1A2A1033649, No. 2016R1D1A1B01010135, No. 2016K1A3A7A09005 603, No. 2016R1D1A1B02012900; Radiation Science Research Institute, Foreign Large-size Research Facility Application Supporting project and the Global Science Experimental Data Hub Center of the Korea Institute of Science and Technology Information; the Polish Ministry of Science and Higher Education and the National Science Center; the Ministry of Education and Science of the Russian Federation and the Russian Foundation for Basic Research; the Slovenian Research Agency; Ikerbasque, Basque Foundation for Science, Basque Government (No. IT956-16) and Ministry of Economy and Competitiveness (MINECO) (Juan de la Cierva), Spain; the Swiss National Science Foundation; the Ministry of Education and the Ministry of Science and Technology of Taiwan; and the United States Department of Energy and the National Science Foundation

Observation of TransverseΛ= ̄ΛHyperon Polarization ine+e−Annihilation at Belle

We report the first observation of the spontaneous polarization of Lambda and (Lambda) over bar hyperons transverse to the production plane in e(+)e(-) annihilation, which is attributed to the effect arising from a polarizing fragmentation function. For inclusive Lambda/(Lambda) over bar production, we also report results with subtracted feed-down contributions from Sigma(0) and charm. This measurement uses a dataset of 800.4 fb(-1) collected by the Belle experiment at or near a center-of-mass energy of 10.58 GeV. We observe a significant polarization that rises with the fractional energy carried by the Lambda/(Lambda) over bar hyperon.We thank the KEKB group for the excellent operation of the accelerator; the KEK cryogenics group for the efficient operation of the solenoid; and the KEK computer group, and the Pacific Northwest National Laboratory (PNNL) Environmental Molecular Sciences Laboratory (EMSL) computing group for strong computing support; and the National Institute of Informatics, and Science Information NETwork 5 (SINET5) for valuable network support. We acknowledge support from the Ministry of Education, Culture, Sports, Science, and Technology (MEXT) of Japan, the Japan Society for the Promotion of Science (JSPS), and the Tau-Lepton Physics Research Center of Nagoya University; the Australian Research Council including Grants No. DP180102629, No. DP170102389, No. DP170102204, No. DP150103061, No. FT130100303; Austrian Science Fund under Grant No. P 26794-N20; the National Natural Science Foundation of China under Contracts No. 11435013, No. 11475187, No. 11521505, No. 11575017, No. 11675166, No. 11705209; Key Research Program of Frontier Sciences, Chinese Academy of Sciences (CAS), Grant No. QYZDJ-SSW-SLH011; the CAS Center for Excellence in Particle Physics (CCEPP); the Shanghai Pujiang Program under Grant No. 18PJ1401000; the Ministry of Education, Youth and Sports of the Czech Republic under Contract No. LTT17020; the Carl Zeiss Foundation, the Deutsche Forschungsgemeinschaft, the Excellence Cluster Universe, and the VolkswagenStiftung; the Department of Science and Technology of India; the Istituto Nazionale di Fisica Nucleare of Italy; National Research Foundation (NRF) of Korea Grants No. 2015H1A2A1033649, No. 2016R1D1A1B01010135, No. 2016K1A3A7A09005 603, No. 2016R1D1A1B02012900, No. 2018R1A2B3003 643, No. 2018R1A6A1A06024970, No. 2018R1D1 A1B07047294; Radiation Science Research Institute, Foreign Large-size Research Facility Application Supporting project, the Global Science Experimental Data Hub Center of the Korea Institute of Science and Technology Information and KREONET/GLORIAD; the Polish Ministry of Science and Higher Education and the National Science Center; the Grant of the Russian Federation Government, Agreement No. 14.W03.31.0026; the Slovenian Research Agency; Ikerbasque, Basque Foundation for Science, Spain; the Swiss National Science Foundation; the Ministry of Education and the Ministry of Science and Technology of Taiwan; and the United States Department of Energy and the National Science Foundation

Multidifferential study of identified charged hadron distributions in ZZ-tagged jets in proton-proton collisions at s=\sqrt{s}=13 TeV

Jet fragmentation functions are measured for the first time in proton-proton collisions for charged pions, kaons, and protons within jets recoiling against a $Z$ boson. The charged-hadron distributions are studied longitudinally and transversely to the jet direction for jets with transverse momentum 20 $< p_{\textrm{T}} < 100$ GeV and in the pseudorapidity range $2.5 < \eta < 4$. The data sample was collected with the LHCb experiment at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 1.64 fb$^{-1}$. Triple differential distributions as a function of the hadron longitudinal momentum fraction, hadron transverse momentum, and jet transverse momentum are also measured for the first time. This helps constrain transverse-momentum-dependent fragmentation functions. Differences in the shapes and magnitudes of the measured distributions for the different hadron species provide insights into the hadronization process for jets predominantly initiated by light quarks.Comment: All figures and tables, along with machine-readable versions and any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-013.html (LHCb public pages

Study of the B−→Λc+Λˉc−K−B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-} decay

The decay $B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-}$ is studied in proton-proton collisions at a center-of-mass energy of $\sqrt{s}=13$ TeV using data corresponding to an integrated luminosity of 5 $\mathrm{fb}^{-1}$ collected by the LHCb experiment. In the $\Lambda_{c}^+ K^{-}$ system, the $\Xi_{c}(2930)^{0}$ state observed at the BaBar and Belle experiments is resolved into two narrower states, $\Xi_{c}(2923)^{0}$ and $\Xi_{c}(2939)^{0}$, whose masses and widths are measured to be $$m(\Xi_{c}(2923)^{0}) = 2924.5 \pm 0.4 \pm 1.1 \,\mathrm{MeV}, \\ m(\Xi_{c}(2939)^{0}) = 2938.5 \pm 0.9 \pm 2.3 \,\mathrm{MeV}, \\ \Gamma(\Xi_{c}(2923)^{0}) = \phantom{000}4.8 \pm 0.9 \pm 1.5 \,\mathrm{MeV},\\ \Gamma(\Xi_{c}(2939)^{0}) = \phantom{00}11.0 \pm 1.9 \pm 7.5 \,\mathrm{MeV},$$ where the first uncertainties are statistical and the second systematic. The results are consistent with a previous LHCb measurement using a prompt $\Lambda_{c}^{+} K^{-}$ sample. Evidence of a new $\Xi_{c}(2880)^{0}$ state is found with a local significance of $3.8\,\sigma$, whose mass and width are measured to be $2881.8 \pm 3.1 \pm 8.5\,\mathrm{MeV}$ and $12.4 \pm 5.3 \pm 5.8 \,\mathrm{MeV}$, respectively. In addition, evidence of a new decay mode $\Xi_{c}(2790)^{0} \to \Lambda_{c}^{+} K^{-}$ is found with a significance of $3.7\,\sigma$. The relative branching fraction of $B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-}$ with respect to the $B^{-} \to D^{+} D^{-} K^{-}$ decay is measured to be $2.36 \pm 0.11 \pm 0.22 \pm 0.25$, where the first uncertainty is statistical, the second systematic and the third originates from the branching fractions of charm hadron decays.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-028.html (LHCb public pages

Measurement of the ratios of branching fractions R(D∗)\mathcal{R}(D^{*}) and R(D0)\mathcal{R}(D^{0})

The ratios of branching fractions $\mathcal{R}(D^{*})\equiv\mathcal{B}(\bar{B}\to D^{*}\tau^{-}\bar{\nu}_{\tau})/\mathcal{B}(\bar{B}\to D^{*}\mu^{-}\bar{\nu}_{\mu})$ and $\mathcal{R}(D^{0})\equiv\mathcal{B}(B^{-}\to D^{0}\tau^{-}\bar{\nu}_{\tau})/\mathcal{B}(B^{-}\to D^{0}\mu^{-}\bar{\nu}_{\mu})$ are measured, assuming isospin symmetry, using a sample of proton-proton collision data corresponding to 3.0 fb${ }^{-1}$ of integrated luminosity recorded by the LHCb experiment during 2011 and 2012. The tau lepton is identified in the decay mode $\tau^{-}\to\mu^{-}\nu_{\tau}\bar{\nu}_{\mu}$. The measured values are $\mathcal{R}(D^{*})=0.281\pm0.018\pm0.024$ and $\mathcal{R}(D^{0})=0.441\pm0.060\pm0.066$, where the first uncertainty is statistical and the second is systematic. The correlation between these measurements is $\rho=-0.43$. Results are consistent with the current average of these quantities and are at a combined 1.9 standard deviations from the predictions based on lepton flavor universality in the Standard Model.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-039.html (LHCb public pages

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

Recent HERMES results from inclusive and semi-inclusive hadron production

4th International Workshop on Transverse Polisarization Phenomena in Hard Processes (TRANSVERSITY 2014)HERMES collected a wealth of data using the 27.6 GeV polarized HERA lepton beam and various pure, polarized and unpolarized, gaseous targets. This unique data set opens the door to various measurements sensitive to the multi-dimensional structure of the nucleon. Among them are two-hadron production in semi-inclusive deep-inelastic scattering on a transversely polarized target, providing access to different transverse-momentum-dependent distribution and fragmentation functions in a way complementary to single-hadron production. Also transverse-target single-spin asymmetries in inclusive electroproduction of charged pions and kaons have been recently extracted, complementing data from proton-proton collisions, where large, so far unexplained, asymmetries have been observed. From inclusive measurements on various nuclear targets, the Lambda polarization is extracted, also here complementing measurements in proton-proton collisions

Observation of Xi(1620)(0) and Evidence for Xi(1690)(0) in Xi(+)(c) -> Xi(-) pi(+) pi(+) Decays

We report the first observation of the double strange baryon Xi(1620)(0) in its decay to Xi(-) pi(+) via Xi(+)(c) -> Xi(-)pi(+)pi(+) decays based on a 980 fb(-1) data sample collected with the Belle detector at the KEKB asymmetricenergy e(+)e(-) collider. The mass and width are measured to be 1610.4 +/- 6.0(stat)(-4.2)(+6.1) (syst) MeV/c(2) and 59.9 +/- 4.8(stat)(-7.1)(+2.8)(syst) MeV, respectively. We obtain 4.0 sigma evidence of the Xi(1690)(0) with the same data sample. These results shed light on the structure of hyperon resonances with strangeness S = -2.We thank the KEKB group for the excellent operation of the accelerator; the KEK cryogenics group for the efficient operation of the solenoid; and the KEK computer group, and the Pacific Northwest National Laboratory (PNNL) Environmental Molecular Sciences Laboratory (EMSL) computing group for strong computing support; and the National Institute of Informatics, and Science Information NETwork 5 (SINET5) for valuable network support. We acknowledge support from the Ministry of Education, Culture, Sports, Science, and Technology (MEXT) of Japan, the Japan Society for the Promotion of Science (JSPS), and the Tau-Lepton Physics Research Center of Nagoya University; the Australian Research Council including Grants No. DP180102629, No. DP170102389, No. DP170102204, No. DP1501 03061, and No. FT130100303; Austrian Science Fund under Grant No. P 26794-N20; the National Natural Science Foundation of China under Contracts No. 11435013, No. 11475187, No. 11521505, No. 11575017, No. 11675166, No. 11705209; Key Research Program of Frontier Sciences, Chinese Academy of Sciences (CAS), Grant No. QYZDJ-SSW-SLH011; the CAS Center for Excellence in Particle Physics (CCEPP); the Shanghai Pujiang Program under Grant No. 18PJ1401000; the Ministry of Education, Youth and Sports of the Czech Republic under Contract No. LTT17020; the Carl Zeiss Foundation, the Deutsche Forschungsgemeinschaft, the Excellence Cluster Universe, and the VolkswagenStiftung; the Department of Science and Technology of India; the Istituto Nazionale di Fisica Nucleare of Italy; National Research Foundation (NRF) of Korea Grants No. 2015H1A2A1033649, No. 2016R1D1A1B01010135, No. 2016K1A3A7 A09005 603, No. 2016R1D1A1B02012900, No. 2018R1A2B3003 643, No. 2018R1A6A1 A06024970, and No. 2018R1D1 A1B07047294; Radiation Science Research Institute, Foreign Large-size Research Facility Application Supporting project, the Global Science Experimental Data Hub Center of the Korea Institute of Science and Technology Information and KREONET/GLORIAD; the Polish Ministry of Science and Higher Education and the National Science Center; the Grant of the Russian Federation Government, Agreement No. 14.W03.31.0026; the Slovenian Research Agency; Ikerbasque, Basque Foundation for Science, Basque Government (No. IT956-16) and Ministry of Economy and Competitiveness (MINECO) (Juan de la Cierva), Spain; the Swiss National Science Foundation; the Ministry of Education and the Ministry of Science and Technology of Taiwan; and the United States Department of Energy and the National Science Foundation

Observation of Υ(2S)→γηb(1S) Decay

We report the observation of gamma(2S) -> gamma eta(b)(1S) based on an analysis of the inclusive photon spectrum of 24.7 fb(-1) of e(+)e(-) collisions at the gamma(2s) center-of-mass energy collected with the Belle detector at the KEKB asymmetric-energy e(+)e(-) collider. We measure a branching fraction of B [gamma(2S) -> gamma eta(b)(1S)] = (6.1(-0.7-0.6)(+0.6+0.9) x 10(-4) and derive an eta(b) (1S) mass of 9394.8(-3.1-2.7)(+2.7+4.5) MeV/c(2), where the uncertainties are statistical and systematic, respectively. The significance of our measurement is greater than 7 standard deviations, constituting the first observation of this decay mode.We thank the KEKB group for the excellent operation of the accelerator; the KEK cryogenics group for the efficient operation of the solenoid; and the KEK computer group, and the Pacific Northwest National Laboratory (PNNL) Environmental Molecular Sciences Laboratory (EMSL) computing group for strong computing support; and the National Institute of Informatics, and Science Information NETwork 5 (SINET5) for valuable network support. We acknowledge support from the Ministry of Education, Culture, Sports, Science, and Technology (MEXT) of Japan, the Japan Society for the Promotion of Science (JSPS), and the Tau-Lepton Physics Research Center of Nagoya University; the Australian Research Council including Grants No. DP180102629, DP170102389, DP170102204, DP150103061, FT130100303; Austrian Science Fund under Grant No. P 26794-N20; the National Natural Science Foundation of China under Contracts No. 11435013, No. 11475187, No. 11521505, No. 11575017, No. 11675166, No. 11705209; Key Research Program of Frontier Sciences, Chinese Academy of Sciences (CAS), Grant No. QYZDJ-SSW-SLH011; the CAS Center for Excellence in Particle Physics (CCEPP); the Shanghai Pujiang Program under Grant No. 18PJ1401000; the Ministry of Education, Youth and Sports of the Czech Republic under Contract No. LTT17020; the Carl Zeiss Foundation, the Deutsche Forschungsgemeinschaft, the Excellence Cluster Universe, and the VolkswagenStiftung; the Department of Science and Technology of India; the Istituto Nazionale di Fisica Nucleare of Italy; National Research Foundation (NRF) of Korea Grants No. 2015H1A2A1033649, No. 2016R1D1A1B01010135, No. 2016K1A3A7A09005 603, No. 2016R1D1A1B0201 2900, No. 2018R1A2B3003 643, No. 2018R1A6A1A0602 4970, No. 2018R1D1 A1B07047294; Radiation Science Research Institute, Foreign Large-size Research Facility Application Supporting project, the Global Science Experimental Data Hub Center of the Korea Institute of Science and Technology Information and KREONET/GLORIAD; the Polish Ministry of Science and Higher Education and the National Science Center; the Grant of the Russian Federation Government, Agreement No. 14.W03.31.0026; the Slovenian Research Agency; Ikerbasque, Basque Foundation for Science, Spain; the Swiss National Science Foundation; the Ministry of Education and the Ministry of Science and Technology of Taiwan; and the U.S. Department of Energy and the National Science Foundation

Observation of an Excited Omega(-) Baryon

Using data recorded with the Belle detector, we observe a new excited hyperon, an Omega*(-) candidate decaying into Xi K-0(-) and Xi K--(S)0 with a mass of 2012.4 +/- 0.7(stat) +/- 0.6(syst) McV/c(2) and a width of Gamma = 6.4(-2.0)(+2.5)(stat) +/- 1.6(syst) MeV. The Omega*(-) is seen primary in gamma(1S), gamma(2S), and gamma(3S) decays.We thank the KEKB group for the excellent operation of the accelerator; the KEK cryogenics group for the efficient operation of the solenoid; and the KEK computer group, the National Institute of Informatics, and the Pacific Northwest National Laboratory (PNNL) Environmental Molecular Sciences Laboratory (EMSL) computing group for valuable computing and Science Information NETwork 5 (SINET5) network support. We acknowledge support from the Ministry of Education, Culture, Sports, Science, and Technology (MEXT) of Japan, the Japan Society for the Promotion of Science (JSPS), and the Tau-Lepton Physics Research Center of Nagoya University; the Australian Research Council; Austrian Science Fund under Grant No. P 26794-N20; the National Natural Science Foundation of China under Contracts No. 11435013, No. 11475187, No. 11521505, No. 11575017, No. 11675166, and No. 11705209; Key Research Program of Frontier Sciences, Chinese Academy of Sciences (CAS), Grant No. QYZDJ-SSW-SLH011; the CAS Center for Excellence in Particle Physics (CCEPP); Fudan University Grants No. JIH5913023, No. IDH5913011/003, No. JIH5913024, and No. IDH5913011/002; the Ministry of Education, Youth and Sports of the Czech Republic under Contract No. LTT17020; the Carl Zeiss Foundation, the Deutsche Forschungsgemeinschaft, the Excellence Cluster Universe, and the VolkswagenStiftung; the Department of Science and Technology of India; the Instituto Nazionale di Fisica Nucleare of Italy; National Research Foundation (NRF) of Korea Grants No. 2014R1A2A2A01005286, No. 2015R1A2A2A01003280, No. 2015H1A2A1033649, No. 2016R1D1A1B01010135, No. 2016K1A3A7A09005 603, and No. 2016R1D1A1B02012900; Radiation Science Research Institute, Foreign Large-size Research Facility Application Supporting project and the Global Science Experimental Data Hub Center of the Korea Institute of Science and Technology Information; the Polish Ministry of Science and Higher Education and the National Science Center; the Grant of the Russian Federation Government, Agreement No. 14.W03.31.0026, the Slovenian Research Agency; Ikerbasque, Basque Foundation for Science, Basque Government (Grant No. IT956-16) and Ministry of Economy and Competitiveness (MINECO) (Juan de la Cierva), Spain; the Swiss National Science Foundation; the Ministry of Education and the Ministry of Science and Technology of Taiwan; and the U.S. Department of Energy and the National Science Foundation