Letter, 1946 October 14, from Esther Van Sciver to Carson Robison

1 page, Bob Miller Inc. is a publishing company that Robison uses often. Esther is apparently a friend of Robison and his family

Experiment for transient effects of sudden catastrophic loss of vacuum on a scaled superconducting radio frequency cryomodule

Safe operation of superconducting radio frequency (SRF) cavities require design consideration of a sudden catastrophic loss of vacuum (SCLV) adjacent with liquid helium (LHe) vessels and subsequent dangers. An experiment is discussed to test the longitudinal effects of SCLV along the beam line of a string of scaled SRF cavities. Each scaled cavity includes one segment of beam tube within a LHe vessel containing 2 K saturated LHe, and a riser pipe connecting the LHe vessel to a common gas header. At the beam tube inlet is a fast acting solenoid valve to simulate SCLV and a high/low range orifice plate flow-meter to measure air influx to the cavity. The gas header exit also has an orifice plate flow-meter to measure helium venting the system at the relief pressure of 0.4 MPa. Each cavity is instrumented with Validyne pressure transducers and Cernox thermometers. The purpose of this experiment is to quantify the time required to spoil the beam vacuum and the effects of transient heat and mass transfer on the helium system. Heat transfer data is expected to reveal a longitudinal effect due to the geometry of the experiment. Details of the experimental design criteria and objectives are presented.Comment: 8 pp. Cryogenic Engineering Conference and International Cryogenic Materials Conference CEC-ICMC. 13-17 June 2011. Spokane, Washingto

MAARSS: Magnet Architectures and Active Radiation Shielding Study

Protecting humans from space radiation is a major hurdle for human exploration of the solar system and beyond. Like on Earth, large magnetic fields surrounding a spaceship would deflect charged particles away from the habitat region and reduce the radiation dose to acceptable limits. The objective of this study is to determine the feasibility of current state of the art (SOA) high temperature superconducting (HTS) magnets as a means to protect crew from space radiation exposure on long duration missions beyond Low Earth Orbit (LEO). The study will look at architecture concepts to deflect high energy Galactic Cosmic Radiation (GCR) and Solar Proton Events (SPEs). Mass, power, and shielding efficiency will be considered and compared with current passive shielding capabilities. This report will walk the reader through several designs considered over the one year study and discuss the multiple parameters that should be evaluated for magnetic shielding. The study team eventually down-selects to a scalable light weight solenoid architecture that is launchable and then deployable using magnetic pressure to expand large diameter coils. Benefitting from the low temperature and high vacuum environment of deep space, existing high-temperature superconductors make such radiation shields realistic, near-term technical developments

Development of an Equitable, Interprofessional Medical Cannabis Education, Certification and Research Program in an NCI-Designated Cancer Center

Background: Medical cannabis (MC), state-regulated cannabis programs accessible with a physician certification for a qualifying diagnosis, now exist in 47 states. Little attention has been paid to ensuring equitable access to such programs for the most vulnerable cancer patients.1 Estimates of cannabis use in cancer patients range from 30-40%2 yet access to MC is highly dependent on a number of variables including: geography, cost, availability of certifying providers, lack of provider education and a confusing array of state programs coupled with ongoing federal illegality. The historic criminalization of cannabis and the disproportionate impact on People of Color creates another significant barrier. Most state MC programs require patients to have a variety of skills and resources to participate. These may include internet access, email addresses, a credit or debit card, funds to pay for the certifying visit and product and the ability to access a proximal dispensary.https://jdc.jefferson.edu/medoncposters/1014/thumbnail.jp

Dose-Response of Aerobic Exercise on Cognition: A Community-Based, Pilot Randomized Controlled Trial

Epidemiological studies suggest a dose-response relationship exists between physical activity and cognitive outcomes. However, no direct data from randomized trials exists to support these indirect observations. The purpose of this study was to explore the possible relationship of aerobic exercise dose on cognition. Underactive or sedentary participants without cognitive impairment were randomized to one of four groups: no-change control, 75, 150, and 225 minutes per week of moderate-intensity semi-supervised aerobic exercise for 26-weeks in a community setting. Cognitive outcomes were latent residual scores derived from a battery of 16 cognitive tests: Verbal Memory, Visuospatial Processing, Simple Attention, Set Maintenance and Shifting, and Reasoning. Other outcome measures were cardiorespiratory fitness (peak oxygen consumption) and measures of function functional health. In intent-to-treat (ITT) analyses (n = 101), cardiorespiratory fitness increased and perceived disability decreased in a dose-dependent manner across the 4 groups. No other exercise-related effects were observed in ITT analyses. Analyses restricted to individuals who exercised per-protocol (n = 77) demonstrated that Simple Attention improved equivalently across all exercise groups compared to controls and a dose-response relationship was present for Visuospatial Processing. A clear dose-response relationship exists between exercise and cardiorespiratory fitness. Cognitive benefits were apparent at low doses with possible increased benefits in visuospatial function at higher doses but only in those who adhered to the exercise protocol. An individual’s cardiorespiratory fitness response was a better predictor of cognitive gains than exercise dose (i.e., duration) and thus maximizing an individual’s cardiorespiratory fitness may be an important therapeutic target for achieving cognitive benefits

Superconducting magnets in high-radiation environment at super colliders

The principal challenges arising from beam-induced energy deposition in superconducting (SC) magnets at high-energy high-luminosity hadron and lepton colliders are described. Radiation constraints are analyzed that include quench stability, dynamic heat loads on the cryogenic system, radiation damage limiting the component lifetime, and residual dose rates related to hands-on maintenance. These issues are especially challenging for the interaction regions (IR), particularly for the considered upgrade layouts of the Large Hadron Collider. Up to a few kW of beam power can dissipate in a single SC magnet, and a local peak power density can substantially exceed the quench levels. Just formally, the magnet lifetime is limited to a few months under these conditions. Possible solutions and the ways to mitigate these problems are described in this paper along with R&D needed