1,090 research outputs found

    Vacuum Modified Gravity as an explanation for flat galaxy rotation curves

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    A theory is proposed which allows explaining the observed flat galaxy rotation curves, without needing to invoke dark matter. Whereas other theories have been proposed in the past which realize the same, the present theory rests on basic physical principles, in contrast to for instance the MOND theory. The key to arrive at this new theory is to consider from the start the energy density of the vacuum. The way to calculate the effect of the corresponding vacuum pressure on a mass has previously been laid down by Van Nieuwenhove (1992). We obtain a modification of Newton's law of gravitation with some peculiar properties such as the occurrence of regions of repulsive gravity. Based on a newly derived equation of state of the vacuum, the Tully-Fisher relation is derived. The theory can make detailed predictions about galaxy rotation curves and is also able to explain to the Pioneer anomaly, the foamy distribution of galaxies and the observed accelerated expansion of the universe. A relativistic extension of the theory is included as well.Comment: aacelerated expansion of the universe explained by vacuum modified gravit

    Economic importance of the Belgian ports: Flemish maritime ports, Liège port complex and the port of Brussels – Report 2013. National Bank of Belgium Working Paper No. 283

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    This paper is an annual publication issued by the Microeconomic Analysis service of the National Bank of Belgium. The Flemish maritime ports (Antwerp, Ghent, Ostend, Zeebrugge), the Autonomous Port of Liège and the port of Brussels play a major role in their respective regional economies and in the Belgian economy, not only in terms of industrial activity but also as intermodal centres facilitating the commodity flow. This update paper1 provides an extensive overview of the economic importance and development of the Flemish maritime ports, the Liège port complex and the port of Brussels for the period 2008 - 2013, with an emphasis on 2013. Focusing on the three major variables of value added, employment and investment, the report also provides some information based on the social balance sheet and an overview of the financial situation in these ports as a whole. These observations are linked to a more general context, along with a few cargo statistics. Annual accounts data from the Central Balance Sheet Office were used for the calculation of direct effects, the study of financial ratios and the analysis of the social balance sheet. The indirect effects of the activities concerned were estimated in terms of value added and employment, on the basis of data from the National Accounts Institute. As a result of the underlying calculation method the changes of indirect employment and indirect value added can differ from one another. The developments concerning economic activity in the six ports in 2012 - 2013 are summarised in the table on the next page. The overall decline in maritime traffic seen in the Flemish maritime ports in general in 2012, and in each individual port, was reversed in 2013, but only thanks to growth in Antwerp; the other three ports (Ghent, Ostend and Zeebrugge) experienced a further decrease. In terms of value added, the opposite occurred: a general increase, except in Antwerp, resulting in a slight rise for these ports as a whole. The employment picture was variable, but there was expansion overall, matching the growth of value added, namely 0.3 %. Finally, investment in the Flemish ports declined overall, totalling 3.2 % less in 2013 than in the previous year. In the ports of Liège and Brussels, cargo traffic and employment both declined in 2013. After the sharp fall in 2012, value added at the port of Liège edged upwards again, but in Brussels it recorded a significant decline2. Conversely, investment in Liège was down again, following the surge in 2012, whereas the port of Brussels saw a substantial increase. This report provides a comprehensive account of these issues, giving details for each economic sector, although the comments are confined to the main changes that occurred in 2013

    Preoperative chemoradiation versus radiation alone for stage II and III resectable rectal cancer

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    Background : Preoperative radiotherapy (RT) decreases local recurrence rate and improves survival in stage II and III rectal cancer patients. The combination of chemotherapy with RT has a sound radiobiological rationale, and phase II trials of combined chemoradiation (CRT) have shown promising activity in rectal cancer. Objectives : To compare preoperative RT with preoperative CRT in patients with resectable stage II and III rectal cancer. Search methods : We searched the Cochrane Register of Controlled Trials, Web of Science, Embase.com, and Pubmed from 1975 until June 2012. A manual search was performed of Ann Surg, Arch Surg, Cancer, J Clin Oncol, Int J Radiat Oncol Biol Phys and the proceedings of ASTRO, ECCO and ASCO from 1990 until June 2012. Selection criteria : Relevant studies randomized resectable stage II or III rectal cancer patients to at least one arm of preoperative RT alone or at least one arm of preoperative CRT. Data collection and analysis : Primary outcome parameters included overall survival (OS) at 5 years and local recurrence (LR) rate at 5 years. Secondary outcome parameters included disease free survival (DFS) at 5 years, metastasis rate, pathological complete response rate, clinical response rate, sphincter preservation rate, acute toxicity, postoperative mortality and morbidity, and anastomotic leak rate. Outcome parameters were summarized using the Odds Ratio (OR) and associated 95% confidence interval (CI) using the fixed effects model. Main results : Five trials were identified and included in the meta-analysis. From one of the included trials only preliminary data are reported. The addition of chemotherapy to preoperative RT significantly increased grade III and IV acute toxicity (OR 1.68-10, P = 0.002) and marginally affected postoperative overall morbidity (OR 0.67-1.00, P = 0.05) while no differences were observed in postoperative mortality or anastomotic leak rate. Compared to preoperative RT alone, preoperative CRT significantly increased the rate of complete pathological response (OR 2.12-5.84, P < 0.00001) although this did not translate into a higher sphincter preservation rate (OR 0.92-1.30, P = 0.32). The incidence of local recurrence at five years was significantly lower in the CRT group compared to RT alone (OR 0.39-0.72, P < 0.001). No statistically significant differences were observed in DFS (OR 0.92-1.34, P = 0.27) or OS (OR 0.79-1.14, P = 0.58) at five years. Authors' conclusions : Compared to preoperative RT alone, preoperative CRT enhances pathological response and improves local control in resectable stage II and III rectal cancer, but does not benefit disease free or overall survival. The effects of preoperative CRT on functional outcome and quality of life are incompletely understood and should be addressed in future trials

    Thomas Aquinas on the Sacrifice of Christ and the Eucharist: A Defence

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    In this paper I will discuss one of the soteriological models Thomas Aquinas outlines in his Summa Theologiae, namely ‘sacrifice’. This is only one of several, but not mutually exclusive, ways in which Thomas interprets our salvation in Christ. I will briefly list the other models before focussing in more depth on sacrifice by considering some objections against it. I will continue by outlining Thomas's theology of sacrifice in its own right and explain its connections with the Eucharist. By way of conclusion I will return to the modern criticism raised

    Contemplation, Intellectus, and Simplex Intuitus in Aquinas: Recovering a Neoplatonic Theme

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    This contribution examines two related points in relation to Aquinas’s understanding of contemplation, which is a sorely neglected topic in scholarship. First, after having outlined that the final act of contemplation culminates in an intellective, simple apprehension of the truth, I will examine how this act relates to the three operations of the intellect (grasping of quiddity, judgement, and reasoning) Aquinas identifies in a number of places. Second, I argue that his view of contemplation as simple insight is significantly indebted to Neoplatonic sources; therefore, we must pay attention to the way he introduces Neoplatonic elements into his Aristotelian framework. I conclude this contribution by suggesting some reasons—of a theological nature—why Aquinas would have been drawn towards a non-discursive or “intuitive” notion of contemplation

    Characterization of Trypanosoma brucei gambiense variant surface glycoprotein LiTat 1.5

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    At present, all available diagnostic antibody detection tests for Trypanosoma brucei gambiense human African trypanosomiasis are based on predominant variant surface glycoproteins (VSGs), such as VSG LiTat 1.5. During investigations aiming at replacement of the native VSGs by recombinant proteins or synthetic peptides, the sequence of VSG LiTat 1.5 was derived from cDNA and direct N-terminal amino acid sequencing. Characterization of the VSG based on cysteine distribution in the amino acid sequence revealed an unusual cysteine pattern identical to that of VSG Kinu 1 of T. b. brucei. Even though both VSGs lack the third of four conserved cysteines typical for type A N-terminal domains, they can be classified as type A

    Innovative offshore mussel farming in the Belgian North Sea

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    Problems in the Belgian fisheries sector due to low fish prices, limitations in landings and high fuel costs, are putting pressure on the fishermen to look for other and more sustainable production methods, with the emphasis on diversification. Aquaculture might be a solution for at least a part of the problems. However, the short Belgian coastline is already used intensively for recreation, nature conservation and harbour activities, making coastal aquaculture almost impossible. Recent developments in offshore or open-ocean shellfish culture were a challenge to start aquaculture in the rough North Sea. Culture experiments with blue mussel (Mytilus edulis) started in 1998 at the ropes and grown over a period of 14 months to marketable size mussels. Preliminary experiments show that mussels metal, and parasite (Buck et al., 2005) loads than their inshore relatives, which leads to a fast growth and a healthy product. The different shellfish production areas show differences in spat fall and growth, which indicates that a feasibility study is needed to determine the productivity and specific use of the different areas. The rough North Sea with its erratic waves and strong winds makes it hard to harvest these off-shore mussel cultures. Future research will focus on improvement of the harvesting techniques, mussel area site selection (e.g. windmill farms) and diversification towards other shellfish species such as flat oyster (Ostrea edulis) and scallop (Pecten sp.)
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