María Cristina Salatino. M. T. Cicerón. El orador (a M. Bruto). Introd., anotación y revisión general de traducciones M. C. Salatino. Primera traducción: G. Alonso, G. Franino, S. Fazio, L. Ivars y A. Sbordelati. Mendoza, Jagüel Editores, 2013, 281 pp.

Fil: Aguilera, Valeria. Universidad Nacional de Cuy

The Relationship Between Masculinity & Friendships: A Thematic Analysis On The Qualities of Male Friendships

Certain masculinity norms such as toughness, emotional stoicism, and homophobia appear to be barriers to forming intimate friendships between boys and men. Boys and men who do not successfully build close connections may experience low self-esteem and impaired psychological health. Boys and men who effectively build intimate relationships benefit from peer support and companionship as well as a decrease in anxiety and depression levels. Scholars have yet to conduct a meta-synthesis exploring the relation between masculinity and friendship.https://digitalscholarship.unlv.edu/durep_posters/1093/thumbnail.jp

Hox Genes in Adult Tissues and Their Role in Endothelial Cell Differentiation and Angiogenesis

HOX genes belong to a family of transcription factors characterized by a 183 bp DNA sequence called homeobox, which code for a 61-amino-acid domain defined as the homeodomain. These genes play a central role during embryonic development by controlling body organization, organogenesis, and stem cell differentiation. They can also play a role in adult processes such as embryo implantation, hematopoiesis, and endothelial differentiation. Since endothelial cell differentiation is one of the main steps to initiate vasculogenesis and angiogenesis, we analyzed the role of several Hox genes in the regulation of these two processes. In this chapter, we summarized the evidence to support the function of Hox genes in adult tissues, specifically in endothelial cell differentiation, by studying their mechanism of action and how their target genes regulate vasculogenesis and angiogenesis. Understanding the cellular and molecular mechanisms triggered by Hox biological effects is pivotal for designing new drugs or therapies for high prevalent pathologies, such as cardiovascular diseases

Uncovering Themes of Masculinity Within Male Friendships and Synthesizing Future Interventions

Masculinity norms such as toughness, emotional stoicism, and homophobia are suggested to impede the formation of close male friendships. A lack of close friendships can lead to poor self-esteem and impaired psychological health. Boys and men who effectively build intimate relationships gain from peer support and companionship as well as a decrease in anxiety and depression levels. Scholars have yet to develop a data-driven intervention to assist boys and men in critically analyzing masculinity, thus the current study\u27s findings will contribute to the development of these interventions that could encourage boys and men to properly assess harmful elements of masculinity and establish closer friendships.https://digitalscholarship.unlv.edu/durep_posters/1096/thumbnail.jp

La importancia de la terapia ocupacional en la intervención con familias de niños, niñas y adolescentes pertenecientes a residencias de protección, desde el análisis de discurso de terapeutas ocupacionales que se desempeñan en el área de protección dentro de la quinta región

Tesis (Terapia Ocupacional)El presente estudio es de tipo cualitativo y recalca la importancia del trabajo y rol que cumple el Terapeuta Ocupacional dentro del área de protección de infancia en Chile. UNICEF refiere la protección de la infancia como distintas labores de prevención al maltrato, violencia, explotación y abuso contra niños, niñas y adolescentes (NNA). Es por esta razón que surge el interés de investigar los actos de prevención que realiza el estado por combatir y disminuir las vulneraciones de derechos humanos hacia los NNA que se encuentran en residencias de protección y los aportes que puede proporcionar la Terapia Ocupacional en esta disciplina, principalmente con las familias de los NNA. El último apartado será examinado desde el discurso de tres Terapeutas Ocupacionales que se desempeñan en el área de protección de infancia y posteriormente se realiza un análisis de tipo categorial, el cual nos arrojó como resultados cinco categorías, familia, trabajo familiar desde la disciplina de Terapia Ocupacional, Terapia ocupacional en residencias familiares/protección, trabajo interdisciplinario con familias en residencias y perfil de los NNA.The present study is qualitative and emphasizes the importance of the work and role of the Ocupational Therapist in the área of childhood protection in Chile. UNICEF refers as childhood protection as differen task of prevention of abuse, violence, exploitation and abuse against children and adolescent (boys, girls and teenager, NNA in spanish). It is for that reason that the investigation is carried out, having as focus the acts that the state develope to combat and reduce human right violation fowards children who are in protective residences, as well as the contributions that Occupational Therapy can provide in this discipline, specially with the families of the children. The last section examine from the speech of three Occupational Therapists who work chil pretenccion area and subsequently, a categorical análisis who contains five categories: Family, Family work from the Ocupational Therapy área, Ocupational Therapy in familiary recidence, interdiciplinary family work in recidence and NNA profile

Determinación de control microbiológico de pseudomona en máscaras de pestañas en la ciudad de Cuenca

Introduction: Cosmetic microbiology oversees guaranteeing the safety of cosmetic products; the presence of nosocomial pathogens such as Pseudomonas should be null; however, poor control of Good Manufacturing Practices (GMP) during the manufacture of makeup can generate contamination by this microorganism and put the consumer's health at risk. Therefore, the FDA emphasizes the importance of performing microbiological tests on all products intended for human use. Objective: To determine the microbiological quality of mascaras sold in Cuenca, observing if they comply with the maximum limits allowed according to the Colombian Mandatory Health Notification (NSO, by its Spanish acronym) for Pseudomonas. Methodology: A pure experimental study was conducted on five different mascara brands, applying the guidelines given by the FDA for a microbiological analysis. The identification of Pseudomonas sp was based on identification tests performed in the laboratory. Results: Five mascara brands were analyzed, including two Ecuadorian and three imported brands. Considering that only one of the imported brands showed growth for Pseudomonas sp, this was confirmed through microbiological analysis, using culture media, specific tests, and statistical analysis of variables using IBM SPSS 26. Conclusion: Identifying Pseudomonas in the mascara brand indicates non-compliance with the NSO, indicating the application’s lack of quality and safety.Introducción: La microbiología cosmética es aquella que garantiza la inocuidad de los productos cosméticos, la presencia de patógenos nosocomiales como Pseudomona debería ser nulo sin embargo, el mal control de las Buenas Prácticas de Manufactura (BPM) durante la manufactura del maquillaje puede generar contaminación por este microorganismo y poner en riesgo la salud del consumidor.  Por lo tanto la FDA resalta la importancia de realizar pruebas microbiológicas a todo producto destinado para el uso humano. Objetivo: Determinar la calidad microbiológica de máscaras de pestañas que se expenden en Cuenca, para observar si cumple con los límites máximos permitidos según la Notificación Sanitaria Obligatoria (NSO) colombiana para Pseudomona. Metodología: Se realizó un estudio experimental puro, en 5 marcas de máscaras de pestañas diferentes aplicando las pautas dadas por la FDA para un análisis microbiológico. La identificación de Pseudomona sp se dio con base en las pruebas de identificación realizadas en el laboratorio. Resultados: Se analizó un total de 5 marcas de máscaras de pestañas de las cuales, 2 son marcas ecuatorianas y 3 marcas importadas. Teniendo en cuenta que solo una de las marcas importadas presentó crecimiento positivo para Pseudomona sp esto se confirmó mediante el análisis microbiológico, con la aplicación de medios de cultivo y pruebas específicas, además de un análisis estadístico de las variables mediante la aplicación IBM SPSS 26. Conclusión: La identificación de Pseudomona en la marca de máscaras de pestañas señala un incumplimiento en la NSO, indicando la falta de calidad y seguridad en su aplicación. Tipo de articulo: Original. Área de estudio o rama de la ciencia: Bioquímica y Farmaci

Consultas odontológicas de mujeres consumidoras de cannabis y/o cocaína versus no consumidoras. Estudio de cohorte retrospectivo durante 4 años en Argentina

Introducción: El consumo de cannabis y de cocaína constituye un problema global que afecta la salud bucal. La mayoría de las investigaciones se han realizado en hombres, en programas de rehabilitación. Objetivo: describir y comparar consultas y diagnósticos odontológicos de mujeres consumidoras y no consumidoras de cocaína y/o cannabis, por un período de 4 años. Métodos: estudio de cohorte retrospectivo. Grupos comparados de mujeres consumidoras y no consumidoras de cannabis y/o cocaína, seleccionadas en el posparto en un hospital público. Resultados: la edad promedio en ambos grupos fue de 22 años, sin diferencias en nivel educativo. Las mujeres del grupo de consumidoras (n=29) fueron mayormente policonsumidoras, realizaron más consultas odontológicas de emergencias (p=0,0002), y presentaron más gingivitis y periodontitis (p=0,0001) que las no consumidoras (n=58). Conclusiones: las mujeres consumidoras de cannabis y/o cocaína realizaron más consultas por emergencias, y presentaron con mayor frecuencia diagnóstico de gingivitis y periodontitis que las no consumidoras

Transformações de práticas avaliativas na escola a partir de uma perspectiva da liderança dos professores

This article has the goal of highlighting the need to perform an impactful change in education. For this purpose, we reflect on the assessment practices and teacher leadership forms needed to transform the educational core by focusing on the concept of assessment as learning. We researched and categorized different assessment types associated with teaching at schools in order to explain how each one of them understands and guides learning according to a specific vision of the relationship between the teacher, the student, and the curricular contents. To further discuss this need for change, we analyzed several Latin-American approaches that do not align with conventional schooling. We highlight the experiences of Colombia, Uruguay and Mexico.Este artículo tiene como finalidad destacar la necesidad de realizar un cambio significativo en la educación. Para ello, se reflexiona sobre las prácticas evaluativas y las formas de liderazgo docente necesarias para transformar el núcleo pedagógico centrándonos en el enfoque de evaluación como aprendizaje. Se requirió investigar y sistematizar los distintos tipos de evaluación vinculados al aprendizaje escolar para explicitar cómo cada uno concibe y orienta el aprendizaje según una visión particular de la relación entre docente, estudiante y contenidos curriculares. Además, a fin de profundizar en el desafío de la transformación, se revisaron iniciativas latinoamericanas con enfoques que se desligan de la escolarización convencional, entre las que se destacan las experiencias de Colombia, Uruguay y México.Este artigo tem como objetivo destacar a necessidade de mudanças significativas na educação. Para isso, nós refletimos sobre as práticas avaliativas e as formas da liderança dos professores necessárias para transformar o núcleo pedagógico, com o foco na avaliação como aprendizagem. Foi necessário investigar e sistematizar os diferentes tipos de avaliação relacionados com a aprendizagem escolar para explicitar como cada um concebe e orienta a aprendizagem de acordo com uma visão particular da relação entre professor, aluno e conteúdos curriculares. Além disso, para aprofundar na necessidade de transformação, foram revisadas iniciativas latino-americanas com abordagens que se afastam da escolaridade convencional, entre as quais se destacam as experiências da Colômbia, Uruguai e México

Ceramide chain length–dependent protein sorting into selective endoplasmic reticulum exit sites

Protein sorting in the secretory pathway is crucial to maintain cellular compartmentalization and homeostasis. In addition to coat-mediated sorting, the role of lipids in driving protein sorting during secretory transport is a longstanding fundamental question that still remains unanswered. Here, we conduct 3D simultaneous multicolor high-resolution live imaging to demonstrate in vivo that newly synthesized glycosylphosphatidylinositol-anchored proteins having a very long chain ceramide lipid moiety are clustered and sorted into specialized endoplasmic reticulum exit sites that are distinct from those used by transmembrane proteins. Furthermore, we show that the chain length of ceramide in the endoplasmic reticulum membrane is critical for this sorting selectivity. Our study provides the first direct in vivo evidence for lipid chain length–based protein cargo sorting into selective export sites of the secretory pathway.Spanish Ministry of Economy and Competitiveness (MINECO; grant number BFU2017-89700-P)University of Seville (VIPPIT-2020-I.5)Japan Society for the Promotion of Science (JP25221103, JP17H06420, and JP18H05275)Swiss National Science Foundation (grant no. 163966)Swiss National Supercomputing Centre (CSCS) under project IDs s726 and s84

PREDIRCAM eHealth platform for individualized telemedical assistance for lifestyle modification in the treatment of obesity, diabetes, and cardiometabolic risk prevention: a pilot study (PREDIRCAM 1)

Background: Healthy diet and regular physical activity are powerful tools in reducing diabetes and cardiometabolic risk. Various international scientific and health organizations have advocated the use of new technologies to solve these problems. The PREDIRCAM project explores the contribution that a technological system could offer for the continuous monitoring of lifestyle habits and individualized treatment of obesity as well as cardiometabolic risk prevention. Methods: PREDIRCAM is a technological platform for patients and professionals designed to improve the effectiveness of lifestyle behavior modifications through the intensive use of the latest information and communication technologies. The platform consists of a web-based application providing communication interface with monitoring devices of physiological variables, application for monitoring dietary intake, ad hoc electronic medical records, different communication channels, and an intelligent notification system. A 2-week feasibility study was conducted in 15 volunteers to assess the viability of the platform. Results: The website received 244 visits (average time/session: 17 min 45 s). A total of 435 dietary intakes were recorded (average time for each intake registration, 4 min 42 s ± 2 min 30 s), 59 exercises were recorded in 20 heart rate monitor downloads, 43 topics were discussed through a forum, and 11 of the 15 volunteers expressed a favorable opinion toward the platform. Food intake recording was reported as the most laborious task. Ten of the volunteers considered long-term use of the platform to be feasible. Conclusions: The PREDIRCAM platform is technically ready for clinical evaluation. Training is required to use the platform and, in particular, for registration of dietary food intake