O mobiliário civil setecentista da “Cela de Santo Ambrósio” do Museu de Arouca

The so-called “St. Ambrose Cell”, in the Museum of Arouca (Portugal), is a show-case revealing the interaction of religious apparatus and vernacular domestic furniture. Many stylistic references crossed Portuguese late eighteenth-century Decorative Arts. This miniature reveals a semi-private space of a religious scholar, where he could pray, write and socialize. It’s studded with a multitude of pieces representative of the Portuguese civil fashion of the eighteenth century. Several chairs, a settee, a table, a cabinet as well books in two shelves of English influence are decorated with crimson silk fabric. Two cages hang from the ceiling. A monkey and a parrot on their perches are signs of colonial exoticism of the time.La representación, en miniatura, de la “ célula de San Ambrosio “, en el Museo de Arouca (Portugal), revela la interacción de mobiliario religioso con piezas domesticas en un ambiente privado de finales del siglo XVIII, una época en que muchas referencias estilísticas a cruzaron. Elementos arquitectónicos barrocos son el escenario en el que bustos, platos, espejos y accesorios de plata se muestran en una profusión que revela el cosmopolitismo de entornos portugueses coetáneos. Este artefacto fue diseñado y ejecutado para marcar el espacio de un monje erudito, y está salpicada con una multitud de piezas representativas de la moda civil portuguesa del siglo XVIII. Varias sillas y un canapé, una mesa, un buró, así como dos estantes con influencia inglesa se disponen en un entorno marcado por la tela de seda carmesí. Dos jaulas cuelgan del techo. Un mono y un loro en sus perchas son signos del exotismo colonial de la época.A representação, em miniatura, da chamada “Cela de Santo Ambrósio”, do Museu de Arouca (Portugal), revela-nos a interacção do mobiliário religioso com peças do quotidiano doméstico num ambiente privado de finais do século XVIII, uma época em que múltiplas referências estilísticas se cruzaram. Os elementos arquitectónicos barrocos que envolvem o ambiente constituem o cenário em que bustos, louça, espelhos e luminárias de prata são apresentados, numa profusão que revela o cosmopolitismo dos ambientes portugueses coevos. Esta maquineta foi concebida, e executada, para assinalar o espaço de um monge letrado, e está guarnecida com uma multiplicidade de peças representativas da moda civil portuguesa do século XVIII. Diversas cadeiras e um canapé, uma mesa, uma cómoda-papeleira bem como duas estantes de influência inglesa estão dispostos em ambiente marcado por tecido carmesim de seda. Duas gaiolas pendem do tecto. Um macaco e um papagaio em seus poleiros constituem sinais do exotismo colonial da época

Os testamentos dos contratadores do pau-brasil David Purry, Joseph Mellish e Gerard De Visme e algumas notas sobre a influência do mobiliário setecentista inglês em Portugal. O caso dos “leitos imperiais”

The close links of the 18th century foreign community and the Portuguese elite are revealed in the three British merchants wills, now transcribed. Their important Lisbon palaces and gardens were a show-case of the British fashion abroad. The “state beds”, eventually more than one in each residence, were one of the prestigious and essential typology to display its owner status. Valuable and bright silk and even golden and silver embroideries completely covered the wooden structure of this kind of bed. From the middle of the eighteenth century on the neoclassical fashion gave place to a compromise between upholsterers and a more visible cabinet-makers’ work.Os testamentos transcritos revelam ligações estreitas entre mercadores estrangeiros e suas famílias com a comunidade portuguesa setecentista. O estabelecimento de residências próprias dos ingleses em Lisboa deu lugar a réplicas locais da moda da corte britânica. Uma das tipologias de prestígio de Seiscentos e Setecentos, o “leito imperial”, foi reproduzido nas casas nobres das elites portuguesas. A construção destes leitos, que inicialmente valorizou somente os tecidos ricos importados e aplicações de ouro e prata , deu lugar ao longo do século XVIII a uma maior visibilidade da madeira, proporcionando trabalhos de marcenaria e entalhamento de carácter marcadamente nacional

Eighteenth century technological efficiency: the reuse of Brazilian sugar chest wood in Portuguese cabinet manufacture

We studied decorative Portuguese furniture from the 18th century Clérigos Church in Porto, to identify the woods used, to analyze their possible origin and understand the criteria for wood choice, according to sample location. We identified wood from Acacia sp., Castanea sativa, Couratari sp. and Dalbergia nigra. D. nigra, Acacia sp. and Couratari sp. may have arrived from Brazil, according to their natural distribution and the Portuguese colonial routes; C. sativa was abundant in the North Region of Portugal. In the 18th century, golden metal brass over black furniture was in fashion in Portuguese ecclesiastical cabinet making. Due to its dark colour, Dalbergia nigra was a desirable wood for the exposed structures of ecclesiastical furniture, such as top drawers and top tables. Couratari is a pale wood. Therefore, it was used in the inner structure of the drawers and legs. Acacia wood was also used in internal parts due to its durability. C. sativa was local and extensive; its wood was used in the inner structures, where it could not be seen. Marks were found in the Couratari wood, which indicated that the timber from chest boards employed to carry sugar from Brazil to Portugal was reused. The high silica content of Couratari wood makes it ideal for building “sugar chests”.POCI 2010 (Programa Operacional Ciência e Inovação 2010). Government and the European Union by the FEDER (Fundo Europeu para o Desenvolvimento Regional). Portuguese Foundation for Science and Technology (FCT)info:eu-repo/semantics/publishedVersio

Wood identification of 18th century furniture. Interpreting wood naming inventories

The 18th century Portuguese church furniture represents an extraordinary richness recognised worldwide, which demands safeguarding and valorisation. The identification of the wood of furniture artworks is the most important component for its comprehension and preservation. In this work wood anatomical characters of an 18th century Portuguese decorative furniture set from the Colegiada de São Martinho de Cedofeita, in Porto, were analysed to identify the woods used for manufacturing and to clarify their common names. Furthermore, the objectives were to recognise some of the criteria for choice of wood as well as the source of each wood. The woods identified from 16 fragments belong to Apuleia sp., Acacia sp., Neolamarckia sp. and Castanea sativa. Apuleia sp. and Acacia sp. woods most likely arrived from Brazil, while the Neolamarckia sp. woods likely arrived from India and the C. sativa woods from Portugal. The results are in accordance with the known Portuguese colonial sea routes of the 15th -18th centuries. Interestingly the terms found in the inventories can refer to finishing methods instead to the name of the woods, as for instance “oil wood” can refer to “oiled wood” or “linseed oiled wood”. The species choice may be related to the mechanical properties of the wood as well as the original tree size. Two large planks of Acacia sp. were used for the top of the “Portuguese arcaz”, and Apuleia sp. was found on main structural elements of this set of furniture, suggesting that wood colour was also important. Woods from Neolamarckia sp. and C. sativa, were also identified, being Castanea wood present only in the most recent pieces of the furniture set

Matrizes inglesas no mobiliário português da segunda metade do século XVIII

A marcenaria portuguesa da segunda metade de Setecentos foi influenciada pela chegada da exportação inglesa de mobiliário, que decorreu ao longo de todo o século XVIII. As tipologias inglesas, desenhadas por riscadores com novas ideias, foram executadas numa escala menos ostentatória que as de utilização na corte e nas residências da nobreza, destinando-se a um novo modo de vida em que a sociabilidade era protagonista. O grande comércio dos negócios intercontinentais gerava movimento relevante de pessoas e de circulação de capitais, e os comerciantes ingleses e portugueses – nomeadamente na cidade do Porto –, perfilharam novas modas decorativas. A nova sensibilidade requeria peças para mobilar as residências destas classes emergentes e dos grupos intermédios que viviam, em maioria, nas cidades portuárias. As oficinas de marcenaria foram contagiadas, por outro lado, por ideias gravadas – ou mesmo desenhos –, que chegavam de múltiplas latitudes europeias que tiveram de adaptar à abundância das madeiras indígenas e às que chegavam das colónias, entre elas o Brasil. Traduziram, então, as múltiplas ideias recebidas com uma técnica desenvolta que o passado de ensamblamento concedia aos oficiais, o que originou uma produção idiossincrática com madeira maciça, promovendo o entalhamento e os embutidos. As peças do Rococó e o do Neoclassicismo portuguesas foram, assim, concebidas não só pela integração de elementos estilísticos reconhecíveis na produção internacional – dando origem a peças de mobiliário identificadas com essas correntes estéticas –, mas também pela inclusão de factores regionais, de tradição vivencial local, o que permitiu que brotasse uma outra via da produção de mobiliário – a que adaptou, de modo próprio, elementos estéticos forasteiros ao modo trabalhar local.Portuguese cabinet-making was influenced by the eighteenth-century English furniture export, as Portugal was one of the destinations of the so called “South Mediterranean Trade”. The English typologies were conceived by newly born designers in a less ostentatious manner than those of the residences of the nobility, and were meant to provide a new way of life in which sociability had a leading role. That production supposed to furnish the homes of the emerging classes living mostly in the port cities. The intercontinental business generated significant movement of people and of money, and the British and Portuguese traders - especially in Porto – asked for those new decorative fashions. The joiner’s workshops were contaminated, on the other hand, by other dynamic features – for instance, the foreign drawings that were carried by tradesmen from multiple European latitudes. Locally, there was abundance of woods, some indigenous and others arriving from the colonies, namely Brasil. Portuguese cabinet-makers translated, in an agile way, those numerous ideas, which led to an idiosyncratic production with carving or inlaid wood. Portuguese Rococo and Neoclassicism incorporated, in consequence, the recognizable stylistic elements of the international production, but also included regional factors, which enabled the sprout of idiosyncratic furniture production that adapted, in a regional feeling, foreign aesthetic elements

Guia para a construção de espaços culturais inclusivos

A criação de espaços culturais e artísticos inclusivos requer uma revisão da forma como estes são concebidos, desenhados e organizados com o objetivo de dar as boasvindas a toda a gente e garantir o acesso e participação igualitários aos serviços, atividades e conteúdos que oferecem. Desta maneira, museus, centros culturais e artísticos ou espaços de exposições contribuem para a promoção do direito a aceder e participar na vida cultural e artística, tal como expresso em várias convenções internacionais, incluindo a Declaração Universal dos Direitos Humanos.info:eu-repo/semantics/publishedVersio

Wood Identification of 18th Century Furniture. Interpreting Wood Naming Inventoires

The 18th century Portuguese church furniture represents an extraordinary richness recognised worldwide, which demands safeguarding and valorisation. The identification of the wood of furniture artworks is the most important component for its comprehension and preservation. In this work wood anatomical characters of an 18th century Portuguese decorative furniture set from the Colegiada de São Martinho de Cedofeita, in Porto, were analysed to identify the woods used for manufacturing and to clarify their common names. Furthermore, the objectives were to recognise some of the criteria for choice of wood as well as the source of each wood. The woods identified from 16 fragments belong to Apuleia sp., Acacia sp., Neolamarckia sp. and Castanea sativa. Apuleia sp. and Acacia sp. woods most likely arrived from Brazil, while the Neolamarckia sp. woods likely arrived from India and the C. sativa woods from Portugal. The results are in accordance with the known Portuguese colonial sea routes of the 15th -18th centuries. Interestingly the terms found in the inventories can refer to finishing methods instead to the name of the woods, as for instance “oil wood” can refer to “oiled wood” or “linseed oiled wood”. The species choice may be related to the mechanical properties of the wood as well as the original tree size. Two large planks of Acacia sp. were used for the top of the “Portuguese arcaz”, and Apuleia sp. was found on main structural elements of this set of furniture, suggesting that wood colour was also important. Woods from Neolamarckia sp. and C. sativa, were also identified, being Castanea wood present only in the most recent pieces of the furniture set

Lung Auscultation Using the Smartphone—Feasibility Study in Real-World Clinical Practice

Conventional lung auscultation is essential in the management of respiratory diseases. However, detecting adventitious sounds outside medical facilities remains challenging. We assessed the feasibility of lung auscultation using the smartphone built-in microphone in real-world clinical practice. We recruited 134 patients (median[interquartile range] 16[11–22.25]y; 54% male; 31% cystic fibrosis, 29% other respiratory diseases, 28% asthma; 12% no respiratory diseases) at the Pediatrics and Pulmonology departments of a tertiary hospital. First, clinicians performed conventional auscultation with analog stethoscopes at 4 locations (trachea, right anterior chest, right and left lung bases), and documented any adventitious sounds. Then, smartphone auscultation was recorded twice in the same four locations. The recordings (n = 1060) were classified by two annotators. Seventy-three percent of recordings had quality (obtained in 92% of the participants), with the quality proportion being higher at the trachea (82%) and in the children’s group (75%). Adventitious sounds were present in only 35% of the participants and 14% of the recordings, which may have contributed to the fair agreement between conventional and smartphone auscultation (85%; k = 0.35(95% CI 0.26–0.44)). Our results show that smartphone auscultation was feasible, but further investigation is required to improve its agreement with conventional auscultation

Relationship between low Ankle-Brachial Index and rapid renal function decline in patients with atrial fibrillation: a prospective multicentre cohort study

OBJECTIVE: To investigate the relationship between Ankle-Brachial Index (ABI) and renal function progression in patients with atrial fibrillation (AF). DESIGN: Observational prospective multicentre cohort study. SETTING: Atherothrombosis Center of I Clinica Medica of 'Sapienza' University of Rome; Department of Medical and Surgical Sciences of University Magna Græcia of Catanzaro; Atrial Fibrillation Registry for Ankle-Brachial Index Prevalence Assessment-Collaborative Italian Study. PARTICIPANTS: 897 AF patients on treatment with vitamin K antagonists. MAIN OUTCOME MEASURES: The relationship between basal ABI and renal function progression, assessed by the estimated Glomerular Filtration Rate (eGFR) calculated with the CKD-EPI formula at baseline and after 2 years of follow-up. The rapid decline in eGFR, defined as a decline in eGFR >5 mL/min/1.73 m(2)/year, and incident eGFR<60 mL/min/1.73 m(2) were primary and secondary end points, respectively. RESULTS: Mean age was 71.8±9.0 years and 41.8% were women. Low ABI (ie, ≤0.90) was present in 194 (21.6%) patients. Baseline median eGFR was 72.7 mL/min/1.73 m(2), and 28.7% patients had an eGFR<60 mL/min/1.73 m(2). Annual decline of eGFR was -2.0 (IQR -7.4/-0.4) mL/min/1.73 m(2)/year, and 32.4% patients had a rapid decline in eGFR. Multivariable logistic regression analysis showed that ABI ≤0.90 (OR 1.516 (95% CI 1.075 to 2.139), p=0.018) and arterial hypertension (OR 1.830 95% CI 1.113 to 3.009, p=0.017) predicted a rapid eGFR decline, with an inverse association for angiotensin converting enzyme (ACE) inhibitors/angiotensin receptor blockers (OR 0.662 95% CI 0.464 to 0.944, p=0.023). Among the 639 patients with AF with eGFR >60 mL/min/1.73 m(2), 153 (23.9%) had a reduction of the eGFR <60 mL/min/1.73 m(2). ABI ≤0.90 was also an independent predictor for incident eGFR<60 mL/min/1.73 m(2) (HR 1.851, 95% CI 1.205 to 2.845, p=0.005). CONCLUSIONS: In patients with AF, an ABI ≤0.90 is independently associated with a rapid decline in renal function and incident eGFR<60 mL/min/1.73 m(2). ABI measurement may help identify patients with AF at risk of renal function deterioration

Risdiplam in Patients Previously Treated with Other Therapies for Spinal Muscular Atrophy: An Interim Analysis from the JEWELFISH Study

Introduction: Risdiplam is a survival of motor neuron 2 (SMN2) splicing modifier for the treatment of patients with spinal muscular atrophy (SMA). The JEWELFISH study (NCT03032172) was designed to assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of risdiplam in previously treated pediatric and adult patients with types 1–3 SMA. Here, an analysis was performed after all patients had received at least 1 year of treatment with risdiplam. Methods: Patients with a confirmed diagnosis of 5q-autosomal recessive SMA between the ages of 6 months and 60 years were eligible for enrollment. Patients were previously enrolled in the MOONFISH study (NCT02240355) with splicing modifier RG7800 or treated with olesoxime, nusinersen, or onasemnogene abeparvovec. The primary objectives of the JEWELFISH study were to evaluate the safety and tolerability of risdiplam and investigate the PK after 2 years of treatment. Results: A total of 174 patients enrolled: MOONFISH study (n = 13), olesoxime (n = 71 patients), nusinersen (n = 76), onasemnogene abeparvovec (n = 14). Most patients (78%) had three SMN2 copies. The median age and weight of patients at enrollment was 14.0 years (1–60 years) and 39.1 kg (9.2–108.9 kg), respectively. About 63% of patients aged 2–60 years had a baseline total score of less than 10 on the Hammersmith Functional Motor Scale–Expanded and 83% had scoliosis. The most common adverse event (AE) was upper respiratory tract infection and pyrexia (30 patients each; 17%). Pneumonia (four patients; 2%) was the most frequently reported serious AE (SAE). The rates of AEs and SAEs per 100 patient-years were lower in the second 6-month period compared with the first. An increase in SMN protein was observed in blood after risdiplam treatment and was comparable across all ages and body weight quartiles. Conclusions: The safety and PD of risdiplam in patients who were previously treated were consistent with those of treatment-naïve patients