The mandibular condyle as uncommon metastatic site of neuroendocrine carcinoma: Case report and review of literature

Temporo-mandibular joint (TMJ) metastases are a very rare event and only 73 cases are reported in literature. In about 40% of cases condylar metastases represent the first clinical manifestation of a tumor of elsewhere and may then allow an early diagnosis. However, the identification of this tumoral process can be difficult as in over 50% of the cases it has a nuanced clinical presentation that is very similar to temporo-mandibular disorders. The first case of metastatic neuroendocrine carcinoma (NEC) of the temporo-mandibular joint (TMJ) mimicking a temporo-mandibular joint disorder is presented in this report. Furthermore, an extensive review of the literature has been performed in order to establish a correct diagnosticâ\u80\u93therapeutic protocol for these oncologic patients

Newer agents for Helicobacter pylori eradication

Helicobacter pylori infection remains widespread internationally, with a definite morbidity and mortality. The efficacy of standard 7–14 day triple therapies is decreasing, mainly due to increasing primary bacterial resistance to antibiotics. Currently, the most effective treatments are either the sequential regimen or the concomitant therapy. Different patents have been registered showing high bactericidal effects in vitro, some of which are active against clarithromycin- and metronidazole-resistant strains, even at low pH values. Among these novel molecules, benzimidazole-derivatives, polycyclic compounds, pyloricidin, and arylthiazole analogues seem to be the more promising. The identification of essential genes for either bacterial colonization or growth represents a route for potential target therapies in the near future

Vertiginous crisis following temporomandibular joint athrocentesis: a case report

Temporomandibular joint arthrocentesis and arthroscopy have recently exceeded open surgeries for disorders that failed to respond to conservative treatment. The efficacy of arthrocentesis in reestablishing normal mouth opening and reducing pain and dysfunctions is now commonly accepted, but in contrast to arthroscopy, there are no large series studies on arthrocentesis complications. We report the major complication occurred in our experience: a case of a patient that complained of a violent vertigo, without hearing disorders, following the procedure

Facing COVID-19 pandemic: development of custom-made face mask with rapid prototyping system

COVID-19 is a global pandemic. The virus spreads through respiratory droplets and close contact. Therefore, the availability of personal protective equipment (PPE) for healthcare professionals is essential. 3D printing technology could represent a valid option to ameliorate PPE shortages