986 research outputs found
The Removal of Artificially Generated Polarization in SHARP Maps
We characterize the problem of artificial polarization for the Submillimeter
High Angular Resolution Polarimeter (SHARP) through the use of simulated data
and observations made at the Caltech Submillimeter Observatory (CSO). These
erroneous, artificial polarization signals are introduced into the data through
misalignments in the bolometer sub-arrays plus pointing drifts present during
the data-taking procedure. An algorithm is outlined here to address this
problem and correct for it, provided that one can measure the degree of the
sub-array misalignments and telescope pointing drifts. Tests involving
simulated sources of Gaussian intensity profile indicate that the level of
introduced artificial polarization is highly dependent upon the angular size of
the source. Despite this, the correction algorithm is effective at removing up
to 60% of the artificial polarization during these tests. The analysis of
Jupiter data taken in January 2006 and February 2007 indicates a mean
polarization of 1.44%+/-0.04% and 0.95%+/-0.09%, respectively. The application
of the correction algorithm yields mean reductions in the polarization of
approximately 0.15% and 0.03% for the 2006 and 2007 data sets, respectively.Comment: 19 pages, 7 figure
From expression pattern to genetic association in asthma and asthma-related phenotypes
Background :
Asthma is a complex disease characterized by hyperresponsiveness, obstruction and inflammation of the airways. To date, several studies using different approaches as candidate genes approach, genome wide association studies, linkage analysis and genomic expression leaded to the identification of over 300 genes involved in asthma pathophysiology. Combining results from two studies of genomic expression, this study aims to perform an association analysis between genes differently expressed in bronchial biopsies of asthmatics compared to controls and asthma-related phenotypes using the same French-Canadian Caucasian population.
Results :
Before correction, 31 of the 85 genes selected were associated with at least one asthma-related phenotype. We found four genes that survived the correction for multiple testing. The rs11630178 in aggrecan gene (AGC1) is associated with atopy (p=0.0003) and atopic asthma (p=0.0001), the rs1247653 in the interferon alpha-inducible protein 6 (IFI6), the rs1119529 in adrenergic, alpha-2A-, receptor (ADRA2A) and the rs13103321 in the alcohol dehydrogenase 1B (class I), beta polypeptide (ADH1B), are associated with asthma (p=0.019; 0.01 and 0.002 respectively).
Conclusion :
To our knowledge, this is the first time those genes are associated with asthma and related traits. Consequently, our study confirms that genetic and expression studies are complementary to identify new candidate genes and to investigate their role to improve the comprehension of the complexity of asthma pathophysiology
The Submillimeter Polarization Spectrum of M17
We present 450 {\mu}m polarimetric observations of the M17 molecular cloud
obtained with the SHARP polarimeter at the Caltech Submillimeter Observatory.
Across the observed region, the magnetic field orientation is consistent with
previous submillimeter and far-infrared polarization measurements. Our
observations are centered on a region of the molecular cloud that has been
compressed by stellar winds from a cluster of OB stars. We have compared these
new data with previous 350 {\mu}m polarimetry and find an anti-correlation
between the 450 to 350 {\mu}m polarization magnitude ratio and the ratio of 21
cm to 450 {\mu}m intensity. The polarization ratio is lower near the east end
of the studied region where the cloud is exposed to stellar winds and
radiation. At the west end of the region, the polarization ratio is higher. We
interpret the varying polarization spectrum as evidence supporting the
radiative alignment torque (RAT) model for grain alignment, implying higher
alignment efficiency in the region that is exposed to a higher anisotropic
radiation field.Comment: 24 pages, 10 figure
Magnetic Field Structure around Low-Mass Class 0 Protostars: B335, L1527 and IC348-SMM2
We report new 350 micron polarization observations of the thermal dust
emission from the cores surrounding the low-mass, Class 0 YSOs L1527,
IC348-SMM2 and B335. We have inferred magnetic field directions from these
observations, and have used them together with results in the literature to
determine whether magnetically regulated core-collapse and star-formation
models are consistent with the observations. These models predict a pseudo-disk
with its symmetry axis aligned with the core magnetic field. The models also
predict a magnetic field pinch structure on a scale less than or comparable to
the infall radii for these sources. In addition, if the core magnetic field
aligns (or nearly aligns) the core rotation axis with the magnetic field before
core collapse, then the models predict the alignment (or near alignment) of the
overall pinch field structure with the bipolar outflows in these sources. We
show that if one includes the distorting effects of bipolar outflows on
magnetic fields, then in general the observational results for L1527 and
IC348-SMM2 are consistent with these magnetically regulated models. We can say
the same for B335 only if we assume the distorting effects of the bipolar
outflow on the magnetic fields within the B335 core are much greater than for
L1527 and IC348-SMM2. We show that the energy densities of the outflows in all
three sources are large enough to distort the magnetic fields predicted by
magnetically regulated models.Comment: Accepted for publication in The Astrophysical Journa
Far-infrared polarimetry from the Stratospheric Observatory for Infrared Astronomy
Multi-wavelength imaging polarimetry at far-infrared wavelengths has proven
to be an excellent tool for studying the physical properties of dust, molecular
clouds, and magnetic fields in the interstellar medium. Although these
wavelengths are only observable from airborne or space-based platforms, no
first-generation instrument for the Stratospheric Observatory for Infrared
Astronomy (SOFIA) is presently designed with polarimetric capabilities. We
study several options for upgrading the High-resolution Airborne Wideband
Camera (HAWC) to a sensitive FIR polarimeter. HAWC is a 12 x 32 pixel bolometer
camera designed to cover the 53 - 215 micron spectral range in 4 colors, all at
diffraction-limited resolution (5 - 21 arcsec). Upgrade options include: (1) an
external set of optics which modulates the polarization state of the incoming
radiation before entering the cryostat window; (2) internal polarizing optics;
and (3) a replacement of the current detector array with two state-of-the-art
superconducting bolometer arrays, an upgrade of the HAWC camera as well as
polarimeter. We discuss a range of science studies which will be possible with
these upgrades including magnetic fields in star-forming regions and galaxies
and the wavelength-dependence of polarization.Comment: 12 pages, 5 figure
Bullying Victimization and Trauma
Bullying victimization and trauma research traditions operate quite separately. Hence, it is unclear from the literature whether bullying victimization should be considered as a form of interpersonal trauma. We review studies that connect bullying victimization with symptoms of PTSD, and in doing so, demonstrate that a conceptual understanding of the consequences of childhood bullying needs to be framed within a developmental perspective. We discuss two potential diagnoses that ought to be considered in the context of bullying victimization: (1) developmental trauma disorder, which was suggested but not accepted as a new diagnosis in the DSM-5 and (2) complex post-traumatic stress disorder, which has been included in the ICD-11. Our conclusion is that these frameworks capture the complexity of the symptoms associated with bullying victimization better than PTSD. We encourage practitioners to understand how exposure to bullying interacts with development at different ages when addressing the consequences for targets and when designing interventions that account for the duration, intensity, and sequelae of this type of interpersonal trauma
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