79 research outputs found

    Que faire des images soviétiques de la Shoah ?

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    La Shoah n’a jamais Ă©tĂ© aussi mĂ©diatique qu’en cette annĂ©e du 70e anniversaire de la « libĂ©ration » des camps aux deux extrĂ©mitĂ©s du IIIe Reich, mais un vĂ©ritable aggiornamento des processus de mĂ©diatisation du gĂ©nocide des Juifs pendant et juste aprĂšs la Seconde Guerre mondiale restait Ă  opĂ©rer. D’autant plus nĂ©cessaire que l’industrie du spectacle (fiction et documentaire, littĂ©rature et albums, tĂ©lĂ©vision et cinĂ©ma) fait fonds sur la fascination morbide du grand public et sur une forme stĂ©rile d’injonction mĂ©morielle le plus souvent sans rĂ©elle rĂ©flexion historienne. Elle persiste en outre Ă  ignorer les apports documentaires et historiographiques induits par l’ouverture des archives soviĂ©tiques. En se focalisant sur les sources filmiques, mais sans nĂ©gliger les autres supports d’information et de propagande du temps de guerre, c’est Ă  cette tĂąche que s’est attelĂ©e l’équipe de chercheurs qui a Ă©laborĂ© l’exposition « Filmer la guerre. Les SoviĂ©tiques face Ă  la Shoah, 1941-1946 », inaugurĂ©e le 8 janvier 2015 au MĂ©morial de la Shoah Ă  Paris. Dans cet article les trois commissaires de l’exposition proposent de revenir sur deux annĂ©es de recherches, en exposant les enjeux, les principes mĂ©thodologiques, et leurs principaux rĂ©sultats. Notamment montrer que les heures de films tournĂ©es par les SoviĂ©tiques sur les crimes de l’occupant en URSS, dans les pays baltes et en Pologne de 1941 Ă  1945 documentent le gĂ©nocide des Juifs en dĂ©tail.With the 70th anniversary of the « liberation » of the camps marked this year, the Holocaust has never been so present in the media. But a re-examination of this mediatisation of the Jewish genocide during and just after World War II is required, especially since the entertainment industry in all its forms merely feeds the morbid fascination of the public while satisfying itself with « commemorations » that lack any real historian reflection : for example, the documentary and historiographical materials revealed by the opening of Soviet archives remain largely ignored. The research team responsible for the exhibition « Filming the War. The Soviets and the Holocaust, 1941-1946 » (Memorial of the Shoah, Paris, 2015) set itself the task of focusing on films from this source, but without neglecting other forms of information and propaganda. In this article the three curators look back on two years of research, outlining their aims, their methodologies, and their main results. In particular they show that the hours of Soviet film document in detail the genocide of the Jews committed by the occupier in the USSR, the Baltic countries, and Poland from 1941 to 1945

    Three Decades of Research on Induced Hypocrisy: A Meta-Analysis

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    International audienceInduced hypocrisy is a sequential, two-step, cognitive dissonance procedure that prompts individuals to adopt a proattitudinal behavior. The present meta-analysis of 29 published and nine unpublished induced-hypocrisy studies enabled us to test three key dissonance-related issues. First, is hypocrisy effective in promoting change in behavioral intention and behavior? Our analyses supported the idea that hypocrisy (vs. control) increased both behavioral intention and behavior. Second, does hypocrisy generate psychological discomfort? Results pertaining to this issue were inconclusive due to the small number of studies measuring psychological discomfort. Third, are both steps necessary to generate change? Effect sizes conform to the idea that the transgressions-only condition can increase both behavior and intention. Our meta-analysis raises a number of theoretical issues concerning the psychological processes underlying induced hypocrisy and highlights implications for practitioners

    The Orexin receptors: Structural and anti-tumoral properties

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    At the end of the 20th century, two new neuropeptides (Orexin-A/hypocretin-1 and Orexin-B/hypocretins-2) expressed in hypothalamus as a prepro-orexins precursor, were discovered. These two neuropeptides interacted with two G protein-coupled receptor isoforms named OX1R and OX2R. The orexins/OX receptors system play an important role in the central and peripheral nervous system where it controls wakefulness, addiction, reward seeking, stress, motivation, memory, energy homeostasis, food intake, blood pressure, hormone secretions, reproduction, gut motility and lipolysis. Orexins and their receptors are involved in pathologies including narcolepsy type I, neuro- and chronic inflammation, neurodegenerative diseases, metabolic syndrome, and cancers. Associated with these physiopathological roles, the extensive development of pharmacological molecules including OXR antagonists, has emerged in association with the determination of the structural properties of orexins and their receptors. Moreover, the identification of OX1R expression in digestive cancers encompassing colon, pancreas and liver cancers and its ability to trigger mitochondrial apoptosis in tumoral cells, indicate a new putative therapeutical action of orexins and paradoxically OXR antagonists. The present review focuses on structural and anti-tumoral aspects of orexins and their receptors

    Near-infrared grating-assisted SPR optical fiber sensors : design rules for ultimate refractometric sensitivity

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    Plasmonic optical fiber sensors are continuously developed for (bio)chemical sensing purposes. Recently, surface plasmon resonance (SPR) generation was achieved in gold-coated tilted fiber Bragg gratings (TFBGs). These sensors probe the surrounding medium with near-infrared narrowband resonances, which enhances both the penetration depth of the evanescent field in the external medium and the wavelength resolution of the interrogation. They constitute a unique configuration to probe all the fiber cladding modes individually. We use them to analyze the modal distribution of gold-coated telecommunication-grade optical fibers immersed in aqueous solutions. Theoretical investigations with a finite-difference complex mode solver are confirmed by experimental data obtained on TFBGs. We show that the refractometric sensitivity varies with the mode order and that the global SPR envelope shift in response to surrounding refractive index (SRI) changes higher than 1e-2 RIU (refractive index unit) can be ~25% bigger than the local SPR mode shift arising from SRI changes limited to 1e-4 RIU. We bring clear evidence that the optimum gold thickness for SPR generation lies in the range between 50 and 70 nm while a cladding diameter decrease from 125 ”m to 80 ”m enhances the refractometric sensitivity by ~20%. Finally, we demonstrate that the ultimate refractometric sensitivity of cladding modes is ~550 nm/RIU when they are probed by gold-coated TFBGs

    Quantum efficiency of energy transfer in noncovalent carbon nanotube/porphyrin compounds

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    International audienceWe report on the quantum yield of excitation energy transfer in non-covalently bound nan- otube/porphyrin compounds. Evidence for energy transfer is gained from photoluminescence exci- tation experiments. We perform a quantitative evaluation of the transfer quantum yield in the case of (6,5) nanotubes through three independent methods : quantitative PLE measurements, evalu- ation of the luminescence quenching of the donor (porphyrin) and ultrafast transient absorption measurements. The latter shows a tremendous increase of the porphyrin recovery rate upon incor- poration in the compound. All these measurements consistently lead to an exceptional quantum yield efficiency

    Interrogation technique for TFBG-SPR refractometers based on differential orthogonal light states

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    The generation of near-IR surface plasmon resonance in gold-coated tilted fiber Bragg gratings is strongly dependent on both the polarization state of the transmission light and the property of confining materials (including the coating materials and surrounding media). These dependencies can be advantageously used to demodulate the amplitude spectrum and retrieve the surrounding refractive index. In this paper, we present an automated demodulation technique that measures the surrounding refractive index by comparing the differential amplitude of resonance peaks near the plasmon attenuation for two orthogonal amplitude spectra recorded in the same operating conditions. A mean sensitivity of more than 500 nm per refractive index unit is reported. This new refractive index measurement method is shown to be accurate to 5×10−5 over a full range of 0.01 in water solutions

    The Anti-tumoral Properties of Orexin/Hypocretin Hypothalamic Neuropeptides: An Unexpected Therapeutic Role

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    Orexins (OxA and OxB) also termed hypocretins are hypothalamic neuropeptides involved in central nervous system (CNS) to control the sleep/wake process which is mediated by two G protein-coupled receptor subtypes, OX1R, and OX2R. Beside these central effects, orexins also play a role in various peripheral organs such as the intestine, pancreas, adrenal glands, kidney, adipose tissue and reproductive tract.In the past few years, an unexpected anti-tumoral role of orexins mediated by a new signaling pathway involving the presence of two immunoreceptor tyrosine-based inhibitory motifs (ITIM) in both orexin receptors subtypes, the recruitment of the phosphotyrosine phosphatase SHP2 and the induction of mitochondrial apoptosis has been elucidated. In the present review, we will discuss the anti-tumoral effect of orexin/OXR system in colon, pancreas, prostate and other cancers, and its interest as a possible therapeutic target

    Rapid response to the M_w 4.9 earthquake of November 11, 2019 in Le Teil, Lower RhĂŽne Valley, France

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    On November 11, 2019, a Mw 4.9 earthquake hit the region close to Montelimar (lower RhĂŽne Valley, France), on the eastern margin of the Massif Central close to the external part of the Alps. Occuring in a moderate seismicity area, this earthquake is remarkable for its very shallow focal depth (between 1 and 3 km), its magnitude, and the moderate to large damages it produced in several villages. InSAR interferograms indicated a shallow rupture about 4 km long reaching the surface and the reactivation of the ancient NE-SW La Rouviere normal fault in reverse faulting in agreement with the present-day E-W compressional tectonics. The peculiarity of this earthquake together with a poor coverage of the epicentral region by permanent seismological and geodetic stations triggered the mobilisation of the French post-seismic unit and the broad French scientific community from various institutions, with the deployment of geophysical instruments (seismological and geodesic stations), geological field surveys, and field evaluation of the intensity of the earthquake. Within 7 days after the mainshock, 47 seismological stations were deployed in the epicentral area to improve the Le Teil aftershocks locations relative to the French permanent seismological network (RESIF), monitor the temporal and spatial evolution of microearthquakes close to the fault plane and temporal evolution of the seismic response of 3 damaged historical buildings, and to study suspected site effects and their influence in the distribution of seismic damage. This seismological dataset, completed by data owned by different institutions, was integrated in a homogeneous archive and distributed through FDSN web services by the RESIF data center. This dataset, together with observations of surface rupture evidences, geologic, geodetic and satellite data, will help to unravel the causes and rupture mechanism of this earthquake, and contribute to account in seismic hazard assessment for earthquakes along the major regional CĂ©venne fault system in a context of present-day compressional tectonics
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