The convenient ambiguity of 'tone': Style and the politics of witnessing in Kate Adie's reporting of the Dunblane tragedy

Kate Adie’s coverage of the 1996 murder of 16 schoolchildren and their teacher in the Scottish town of Dunblane occasioned much critical discussion. Using material from the newly constituted Kate Adie Collection at the University of Sunderland Library, this article looks at aspects of the ‘tone’ and content in Adie’s reports, and reflects upon the ways in which style and practice can position the reporter relative to the affected community. The article highlights the importance of Adie’s established practices and public renown as a high-profile war reporter for the BBC, as well as the socio-political environment of the reports which includes a political resurgence of Scottish nationalism with an associated identity politics. Through critical analysis, the article sets Adie’s reports within a tradition of media ‘bearing witness’ to tragedy, while suggesting that they offer an insight into potential breaches in the assessment of the emotional performativity of witnessing

Recognising Lung Cancer in Primary Care

<p>Full copyright for enhanced digital features is owned by the authors.</p><p><br></p> <p> </p> <p><strong>Article full text</strong></p> <p><br> The full text of this article can be found <a href="https://link.springer.com/article/10.1007/s12325-018-0843-5"><b>here</b>.</a> <br> <br> <strong>Provide enhanced digital features for this article</strong><br> If you are an author of this publication and would like to provide additional enhanced digital features for your article then please contact <u>[email protected]</u>.<br> <br> The journal offers a range of additional features designed to increase visibility and readership. All features will be thoroughly peer reviewed to ensure the content is of the highest scientific standard and all features are marked as ‘peer reviewed’ to ensure readers are aware that the content has been reviewed to the same level as the articles they are being presented alongside. Moreover, all sponsorship and disclosure information is included to provide complete transparency and adherence to good publication practices. This ensures that however the content is reached the reader has a full understanding of its origin. No fees are charged for hosting additional open access content.<br> <br> Other enhanced features include, but are not limited to:<br> • Slide decks<br> • Videos and animations<br> • Audio abstracts<br> • Audio slides</p

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges

Alternative splicing (AS) enables programmed diversity of gene expression across tissues and development. We show here that binding in distal intronic regions (>500 nucleotides (nt) from any exon) by Rbfox splicing factors important in development is extensive and is an active mode of splicing regulation. Similarly to exon-proximal sites, distal sites contain evolutionarily conserved GCATG sequences and are associated with AS activation and repression upon modulation of Rbfox abundance in human and mouse experimental systems. As a proof of principle, we validated the activity of two specific Rbfox enhancers in KIF21A and ENAH distal introns and showed that a conserved long-range RNA-RNA base-pairing interaction (an RNA bridge) is necessary for Rbfox-mediated exon inclusion in the ENAH gene. Thus we demonstrate a previously unknown RNA-mediated mechanism for AS control by distally bound RNA-binding proteins