Electron-phonon interaction via Pekar mechanism in nanostructures

We consider an electron-acoustic phonon coupling mechanism associated with the dependence of crystal dielectric permittivity on the strain (the so-called Pekar mechanism) in nanostructures characterized by strong confining electric fields. The efficiency of Pekar coupling is a function of both the absolute value and the spatial distribution of the electric field. It is demonstrated that this mechanism exhibits a phonon wavevector dependence similar to that of piezoelectricity and must be taken into account for electron transport calculations in an extended field distribution. In particular, we analyze the role of Pekar coupling in energy relaxation in silicon inversion layers. Comparison with the recent experimental results is provided to illustrate its potential significance

Sodium-23 Magnetic Resonance Imaging

23Na MRI provides additional biochemical information to 1H MRI in terms of cell integrity and tissue viability. We aimed at determining the sensitivity of 23Na MRS, MRI and MR relaxometry methods available on 7T MR scanner Bruker Biospec 70/30 USR and developing of an optimal MRI protocol for small animal 23Na in vivo visualization. The outcomes include 23Na MR spectra, 23Na MR images with SNRs, and T1 and T2 values of 23Na. It is shown that single-pulse 23Na MR spectroscopy can discriminate different 23Na concentrations, and 3D FLASH pulse sequence adapted for 23Na data acquisition may provide the acceptable quality images. Keywords: Sodium MRI, Sodium MRS, 3D FLASH, MR relaxometr

Estimation of Innovative Activity of the University

On the basis of Belgorod region innovation activity analysis, positive relationship between shipped innovation items and domestic research and development costs was found. Semantic differential was used for multiple estimation of BelSU innovation activity and competiveness. BelSU integrated index showed high-enough innovation activity of this universityyesBelgorod State Universit

Organización en clúster de industrias extractivas en las regiones del norte: un método de evaluación integral

La organización espacial de las fuerzas productivas, el uso eficiente de las instalaciones disponibles y la evaluación del potencial productivo de los sectores económicos de una región determinada son temas de actualidad. La República de Sakha (Yakutia) es una gran región de Rusia dependiente de los recursos, notable por la dispersión geográfica de los depósitos en un vasto territorio y las complejas infraestructuras de transporte y suministro de energía. Este documento presenta una evaluación integral de la viabilidad de la organización de clusters en el sector de uso del subsuelo en la República de Sakha (Yakutia), Federación de Rusia, teniendo en cuenta la zonificación económica existente y prospectiva y el potencial existente. La república se dividió en zonas basadas en un marco de clúster de los usuarios del subsuelo. El estudio utilizó datos estadísticos de los distritos municipales e indicadores financieros de las empresas de la industria extractiva. En la evaluación se aplicó el método integrado y se calculó el índice de desempeño de los territorios del clúster identificados en una escala de diez puntos. Las zonas identificadas se clasificaron por recursos y potencial de producción. Se calculó el índice de rendimiento general de la zona de conglomerados. Pareció factible agrupar la industria extractiva en la región estudiada, ya que puede aumentar la competitividad de las empresas locales y contribuir al desarrollo socioeconómico de sus distritos municipales. El método propuesto se puede aplicar para una evaluación integral del sector de uso del subsuelo en los territorios del nort

Sistema renovador de reproducción de capacidad profesional como condición efectiva de gestión regional

The article studies the orientation of professional potential reproduction to ensure the effectiveness of regional management, discloses the mechanisms for management professional potential transformation into the indicators of its effectiveness and efficiency. They provided the data of the sociological study “Professional potential reproduction system development among regional management personnel”. The result of the study in this direction was the developed cumulative technology for computer assessment of the competence potential among regional management employees, which includes three blocks: assessment unit, planning unit, and control (correction) unit.El artículo estudia la orientación de la reproducción potencial profesional para garantizar la efectividad de la gestión regional, revela los mecanismos para la transformación del potencial profesional de gestión en los indicadores de su eficacia y eficiencia. Proporcionaron los datos del estudio sociológico “Desarrollo potencial profesional del sistema de reproducción entre el personal de gestión regional”. El resultado del estudio en esta dirección fue la tecnología acumulada desarrollada para la evaluación informática del potencial de competencia entre los empleados de gestión regional, que incluye tres bloques: unidad de evaluación, unidad de planificación y unidad de control (corrección)

STATE GOVERNANCE OF SOCIO-DEMOGRAPHIC PROCESSES IN AGING SOCIETY

Purpose of the study: The main approach of the research is a combination of methodological and applied aspects, including the development of public policy directions aimed at prolonging the active longevity of the Russian population. Methodology: The research used a statistical analysis of the processing of official statistics of Rosstat, data of international organizations - the United Nations (Population Division), the World Bank, the World Health Organization (WHO); analytical - analysis of regulatory legal acts of Russian and international law in the field of regulation. Results: The authors analyze global and Russian trends in an aging society. The influence of the demographic aging of the population on the socio-economic development of the state is revealed. The main directions of the state policy in relation to the aging problems of the population are determined, and the world experience of solving the indicated problems is studied. Applications of this study: This research can be used for the universities, teachers, and students. Novelty/Originality of this study: In this research, the model of state governance of socio-demographic processes in an aging society is presented in a comprehensive and complete manner

DIAGNOSTICS OF PROBLEMS OF REPRODUCTION OF PROFESSIONAL POTENTIAL OF THE STATE AND MUNICIPAL MANAGEMENT AS A PRECONDITION OF ITS SYSTEM RENOVATION

Purpose of the study: This article deals with the renovation system of reproduction of professional potential and provides a definition of this concept. Methodology: The study uses the methods of dialectical contradiction, the ascent from the abstract to the concrete, structural-functional and comparative analysis, theoretical modeling and generalization. Primary sociological information is collected through a questionnaire survey, document analysis, free interview, and observation. Methods of grouping and classification of empirical data, qualitative analysis of factors are also used. Results: the renovation system of reproduction of the professional potential of a state municipal government involves the diagnosis of its problems with the aim of determining the ways of their resolution. The conducted diagnostics identified six groups of actual problems, namely lack of professionalism, the disintegration of indicators of individual and institutional efficiency, the imperfect system of training and advanced training of managerial personnel, the weak motivation of their professional development, inefficient use of professional potential, and passive personnel policy Applications of this study: This research can be used for the universities, teachers, and students. Novelty/Originality of this study: In this research, the model of Diagnostics of Problems of Reproduction of Professional Potential of the State and Municipal Management as a Precondition of Its System Renovation is presented in a comprehensive and complete manner

Nonlinear acousto-electric transport in a two-dimensional electron system

We study both theoretically and experimentally the nonlinear interaction between an intense surface acoustic wave and a two-dimensional electron plasma in semiconductor-piezocrystal hybrid structures. The experiments on hybrid systems exhibit strongly nonlinear acousto-electric effects. The plasma turns into moving electron stripes, the acousto-electric current reaches its maximum, and the sound absorption strongly decreases. To describe the nonlinear phenomena, we develop a coupled-amplitude method for a two-dimensional system in the strongly nonlinear regime of interaction. At low electron densities the absorption coefficient decreases with increasing sound intensity, whereas at high electron density the absorption coefficient is not a monotonous function of the sound intensity. High-harmonic generation coefficients as a function of the sound intensity have a nontrivial behavior. Theory and experiment are found to be in a good agreement.Comment: 27 pages, 6 figure

Transformation approach to implementation of transparency of the Russian supreme audit institution activity

A financial system is generally considered a "circulatory system" of the state, which is essential for its existence. A key role in this system belongs to public funds. That is why issues of improving efficient state audit are becoming extremely important nowaday

Mechanisms of interacting <i>Helicobacter pylori</i> with gastric mucosal epithelium. II. A reaction of gastric epithelium on <i>Helicobacter pylori</i> colonization and persistence

Gastric and duodenal recurrent inflammatory diseases have a high prevalence, but the role played by microbes in its development remained unclear. However, the data published in 1983 by Marshall and Warren about isolating Helicobacter pylori from the stomach mucosa of the patient with gastritis and proposing relevant cultivation methods was the turning point in investigating etiology of the upper digestive tract inflammatory disorders. Moreover, it was shown that the majority of H. pylori spp. are found within the gastric lumen upon colonization, whereas around 20% of them are attached to the epithelial cells in the stomach. In addition, effects of interacting H. pylori with gastric epithelium and activation of some defense mechanisms due to bacterial colonization and spreading were analyzed. It was found that along with triggering pro-inflammatory response induced by proteins VacA as well as phosphorylated/unphosphorylated CagA, wherein the latter is able to induce a set of protective reactions H. pylori disrupts intercellular contacts, affects epithelial cell polarity and proliferation, and activates SHP-2 phosphatase resulting in emerging diverse types of cellular responses. The activation mechanisms for the mitogen-activated protein kinase (MAPK) pathway were discussed. The ability of H. pylori to regulate apoptosis, particularly via its suppression, by expressing ERK kinase and protein MCL1 facilitating bacterial survival in the gastric mucosa as well as beneficial effects related to bacterial circulation on gastric epithelial cell survival elicited by anti-apoptotic factors were also examined. Of note, persistence of H. pylori are mainly determined by activating transcriptional factors including NF-κB, NFAT, SRF, T-cell lymphoid enhancing factor (TCF/LEF), regulating activity of MCL1 protein, in turn, being one of the main anti-apoptotic factors, as well as induced production of the migration inhibitory factor (MIF). The role of VacA cytotoxin in triggering epithelial cell apoptosis via caspase-mediated pathways was also considered. Infection with H. pylori is accompanied by release of proinflammatory cytokine cocktail detected both in vitro and in vivo. In particular, bacterial urease activating transcriptional factor NF-κB was shown to play a crucial role in inducing cytokine production. Moreover, such signaling pathways may be activated after H. pylori is attached to the cognate receptor in the gastric epithelial surface by interacting with CD74 and MHC class II molecules. Finally, a role for various CD4+ T cell subsets, particularly type 17 T helper cells (Th17) in inducing immune response against H. pylori antigens in gastric mucosa was revealed were also discussed