39 research outputs found

    Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia

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    Dal tribale al globale. Introduzione all'antropologia

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    Presentazione critica dell'antropologia culturale e socialeCritical approaches in cultural anthropolog

    Dal Tribale al globale. Introduzione all'antropologia. Nuova Edizione

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    Negli ultimi decenni l'antropologia si è affermata come un sapere capace di leggere la realtà attraverso lo studio dei simboli e dei significati che gli esseri umani conferiscono tanto alla loro vita quotidiana quanto ai grandi fenomeni che si manifestano su scala globale. Analizzando i metodi di indagine, le teorie e gli oggetti attuali della riflessione antropologica, questa nuova edizione, completamente rivista dagli autori, ripercorre idealmente il cammino che ha portato l'antropologia dallo studio di umanità lontane e circoscritte (tribali) a quello di umanità sempre più articolate e vicine tra loro (globali), dove i particolarismi, tuttavia, riemergono con allarmante frequenza e problematicità. Tribale e globale, i due versanti dell'antropologia contemporanea, non vanno quindi intesi come realtà giustapposte, ma come aspetti di una complessità, dove in entrambe le dimensioni ritroviamo elementi dell'una e dell'altra

    EU-US open skies agreement: What is changed in the north transatlantic skies?

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    This article presents analysis of air service levels and competition dynamics in the transatlantic market before and after the EU-US Open Skies Agreement (OSA) signed in 2008. By comparing direct and connecting flights in a typical off-peak week, we investigate whether the EU-US OSA has led to more choices for transatlantic travelers. We examine the impact of the EU-US OSA on competition between carriers, alliances, and hub airports. The results show that the number of direct transatlantic connections and served airport pairsdecreased and only indirect competition increased

    Protective Efficacy in Sheep of Adenovirus-Vectored Vaccines against Bluetongue Virus Is Associated with Specific T Cell Responses.

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    Bluetongue virus (BTV) is an economically important Orbivirus of the Reoviridae family that causes a hemorrhagic disease in ruminants. Its control has been achieved by inactivated-vaccines that have proven to protect against homologous BTV challenge although unable to induce long-term immunity. Therefore, a more efficient control strategy needs to be developed. Recombinant adenovirus vectors are lead vaccine candidates for protection of several diseases, mainly because of their potency to induce potent T cell immunity. Here we report the induction of humoral and T-cell mediated responses able to protect animals against BTV challenge by recombinant replication-defective human adenovirus serotype 5 (Ad5) expressing either VP7, VP2 or NS3 BTV proteins. First we used the IFNAR(-/-) mouse model system to establish a proof of principle, and afterwards we assayed the protective efficacy in sheep, the natural host of BTV. Mice were completely protected against BTV challenge, developing humoral and BTV-specific CD8+- and CD4+-T cell responses by vaccination with the different rAd5. Sheep vaccinated with Ad5-BTV-VP2 and Ad5-BTV-VP7 or only with Ad5-BTV-VP7 and challenged with BTV showed mild disease symptoms and reduced viremia. This partial protection was achieved in the absence of neutralizing antibodies but strong BTV-specific CD8+ T cell responses in those sheep vaccinated with Ad5-BTV-VP7. These data indicate that rAd5 is a suitable vaccine vector to induce T cell immunity during BTV vaccination and provide new data regarding the relevance of T cell responses in protection during BTV infection
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