Effectiveness of Structured Teaching Programme to have Knowledge of Home Management in Bronchial Asthma among selected population at Keezh Seezamangalam Village, Kancheepuram District

Effectiveness of structured teaching programme to have knowledge of home management in bronchial asthma among selected population at Keezh Seezamangalam village, Kancheepuram District. OBJECTIVES : To assess the knowledge of the selected population at Keezh seesamangalam about home management of bronchial asthma. To evaluate effectiveness of structured teaching programme to home management of bronchial asthma among selected population at Keezh seesamangalam. To explore the association between selected demographic variables with the knowledge score among the people residisng at keezh seesamangalam. OPERATIONAL DEFINITION: EFFECTIVENESS :- It refers to a significance increase in the level of knowledge of the population after teaching programme regarding home management of bronchial asthma. KNOWLEDGE: It means the fact, skills and understanding that have gained through learning and experience. STRUCTURED TEACHING PROGRAMME: It refers to system of planned instruction designed to instruct and illustrate to acquire knowledge about home management of bronchial asthma. HOME MANAGEMENT: It refers to adopt providing honey, garlic cloves, figs, fenugreek seeds, ginger and turmeric.etc. This is available at home to prevent complications and severity of bronchial asthma. BRONCHIAL ASTHMA: It refers to recurrent attacks of paroxysmal dyspnea with wheezing due to spasmodic contraction of the bronchi. It is usually either an allergic manifestation. SUMMARY: The present study was conducted to assess effectiveness of structured teaching programme to have knowledge of home management in bronchial asthma among selected population at Keezhu Seezamangalam Village, Kancheepuram District. Quasi experimental research design was used for this study .100 people who met inclusion criteria had been selected from keezhu seesamagalam village by using simple random sampling technique. The investigator first introduced himself to the people and developed a rapport with them. The pre test was conducted with the questionnaire given to the people regarding knowledge of home management in bronchial asthma after Seven days the post test was conducted by using same evaluation tool. The data collected was grouped and analyzed by using descriptive statistics and inferential statistics. CONCLUSION: In pretest out of 100 people, 76(76%) people had inadequate knowledge and 24(24%) had moderately adequate knowledge. In posttest 31 (31%) had moderately adequate knowledge and 69(69%) had adequate knowledge. The „t‟ value 31.721 was compared with tabulated table value at the level of P< 0.05 was significant .So if has been concluded that the structured teaching programme on knowledge of home management of bronchial asthma was effective

Production of cellulase and laccase enzymes by Oudemansiella radicata using agro wastes under solid-state and submerged conditions

Oudemansiella radicata (Relhan ex Fr.) is one of the medicinally important edible mushrooms belonging to Tricholomataceae. In the present study we reported the efficient production of cellulase and laccase enzymes by O. radicata under submerged (SMF) and solid-state (SSF) fermentations. O. radicata had grown well both in submerged and solid-state conditions. Under submerged condition the maximum cellulase activity (490 units / ml / min) was observed. In the case of SSF the maximum cellulase activity was observed as 400 units / ml / min in wheat bran, followed by rice bran (367 units / ml / min). In the case of laccase production, the maximum activity was observed as 1.476 units / ml / min on 14th day at pH 7 under SMF. In solid substrate fermentation the maximum activity was noticed as 25.784 units / ml / min in rice bran. The next higher activity was 11.473 units / ml / min in wheat bran, and the least activity was recorded with saw dust. Higher levels of laccase and cellulase activity were seen in solid-state fermentation than in submerged fermentation. Hence the present results clearly explain that O. radicata is a potential candidate for the production of industrially important enzymes using agro-wastes

ANTIPROLIFERATIVE ACTIVITY OF BIOACTIVE COMPOUNDS FROM MUSHROOMS OF INDIAN ISOLATES

ABSTRACT Biodiversity study on mushrooms of basidiomycetes was initiated and more than seven hundred species were described by Natarajan and associates during 1975-2008 from South India. But the bio-documentation of many medicinal mushrooms were initiated a decade ago by Vaidya and associates from Western India, Janardhanan and associates from Kerala and Kaviyarasan and associates from South India. Lentinus tuberregium, Neolentinus kauffmanii and Agaricus heterocystis, were studied for their medicinal properties such as antitumor, antiviral, antimicrobial and antioxidant activities. These indigenous mushrooms are effective against many cancer lines and induce apoptosis and results in tumor cell death. Antiangiogenesis effect of Trametes hirsuta extract was well established with fertilized hen eggs. These results, clearly established their candidature for drug formulations. Two novel anticancer compounds extracted from Lentinus tuberregium were filed for patent for their anticancer properties. Polysaccharides from Tramates hirusuta, an indigenous isolate was also very effective against many cancer lines. Currently few more edible mushrooms are being studied for their medicinal properties

A rare agaric (Agaricomycetes: Agaricaceae) from a sacred grove of Eastern Ghats, India

Clarkeinda trachodes, a rare tropical Asian agaric was recorded for the first time in the Eastern Ghats, India, from a sacred grove in the Kolli Hills. It is a large lepiotoid fungi characterized by the presence of volva and annulus, with olive brown spore print and small spores with truncated germ pore

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Biosurfactant are surface-active substances synthesized by living cells-in the majority of cases by microorganisms. Metallic contaminants in the soil are poisonous and their accumulation in plants and water may be dangerous. Microorganisms are known to absorb; adsorb and accumulate heavy metals and they can be made use of in solving major problems associated with metals. The extensive use of chromium in different industries such as leather, textile, metal electro plating etc has resulted in the discharge of chromium compounds into aquatic system. Among the fungal isolates, Mucor sp. ATS 5 was predominant using inactive cells about 84 % chromium was removed, whereas in resting cells it was found to be 79%. In the case of bacterial population, Pseudomonas sp. ATS-08 was predominant about 86 % chromium was removed using inactive cells followed by resting cells (75%). Among the actinomycetes isolates, Nocardia sp. ATS-2 was predominant. 90 % chromium was removed using inactive cells of Nocardia sp. followed by resting cells (84%). From the above study, it is concluded that the actinomycetes was the best effective followed by bacteria and fungi and could be used for treating industrial effluents having high amount of chromium. This article can be downloaded from www.ijpbs.ne

EVALUATION OF ANTIMICROBIAL ACTIVITY OF PITHECELLOBIUM DULCE POD PULP EXTRACT

ABSTRACT Objective: Diseases due to pathogenic bacteria and fungi represent a critical problem to human health and they are the major cause of morbidity and mortality worldwide. Plants based antimicrobials are effective in the treatment of infectious diseases while simultaneously mitigating many of the side effects that are often associated with synthetic antimicrobials. In the series of medicinal plants, one such medicinal plant which has been widely used in traditional medicine but lacks scientific scrutiny is Pithecellobium dulce. The present study was aimed to investigate the antimicrobial properties of P.dulce pod pulp extract against common pathogenic gram positive, gram negative bacteria and fungi.Methods: Ethanolic extract was used for the study. Phytochemical screening, total phenolic and flavonoid content were determined. The antibacterial and antifungal activity of ethanolic extract of pod pulp was tested against clinically important Gram positive, Gram negative bacteria and pathogenic fungal strains. The inhibitory effect was assessed by well diffusion method. The Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Minimum Fungicidal Concentration (MFC) were also determined by serial dilution method.Results:  Phytochemical analysis of the pulp extract revealed the presence of alkaloids, flavonoids, glycosides, saponins, phytosterols, and triterpenoids. The pulp extract was found to contain significant amounts of total phenols and flavonoids. The pulp extract showed significant zone of inhibition in a dose dependent manner. The MIC and MBC values of the pulp extract against both Gram positive and Gram negative bacterial strains varies from 1mg to 5mg and the results are comparable with chloramphenicol. The MIC and MFC values of pod pulp extract against fungal strains varies from 1 mg to 7 mg and the results are comparable with Amphotericin B.Conclusion: It can be concluded that the pulp extract possesses potent bactericidal and fungicidal activity which in turn may be due to the presence of biologically active ingredients with antimicrobial activity in the pod pulp.Keywords: Pithecellobium dulce; Antibacterial; Antifungal; Minimum Inhibitory concentratio

Comparitive study on the antioxidant, anticancer and antimicrobial property of Agaricus bisporus (J. E. Lange) Imbach before and after boiling

In this study, ethanol extracts of an edible mushroom Agaricus bisporus, before and after boiling were investigated for antioxidant, anticancer and antimicrobial activities. To confirm the total antioxidantactivity, ABTS, DPPH free radical-scavenging assay was carried, along with total phenolic and flavonoid concentration. In measuring ABTS and DPPH free radical scavenging activities, scavenging activity wasfound to be similar in both the extracts. Total flavonoids were 16.4±0.5 and 15.2±0.2 mg/g (Quercetin equivalent), the phenolics were 90.2±0.6 and 70.6±0.1 mg/g (Catechin equivalent) in raw and boiled extract, respectively. A. bisporus extracts inhibited cell proliferation of HL-60 leukemia by the induction of apoptosis. In addition, A. bisporus extracts exhibited antibacterial activity against both gram positiveand gram negative bacteria, as well as anticandidal activity against Candida albicans. Therefore, A. bisporus could be considered as a functional food with antimicrobial, anti-oxidative and antiproliferative activity

Mushrooms in the food culture of the <i style="mso-bidi-font-style:normal">Kaani</i> tribe of Kanyakumari district

150-153India is inhabited by over 50 million tribals belonging to 550 communities and in Tamil Nadu 36 tribal communities live, while six tribal communities are found in the Southernmost Kanyakumari district. Of the six tribes, <i style="mso-bidi-font-style: normal">Kaani tribe lives in the forests and hills of the Western Ghats. The Kaani tribe lives in consonance with Nature and their life is linked to the forest ecosystem. Though they live in settled areas, they still retain the traditional hunter-gatherer instinct, and collect their food from the forests that include mushrooms. Mushrooms contain a host of defense potentiators, which stimulate the immune system of humans. These mushrooms provide rich resources for the gene banks