69 research outputs found
Застосування звільнення від кримінальної відповідальності у зв’язку з примиренням винного з потерпілим
Алексенко, М. В. Застосування звільнення від кримінальної відповідальності у зв’язку з примиренням винного з потерпілим / Марина Володимирівна Алексенко // Шляхи удосконалення досудового розслідування: організаційно-правові аспекти : матеріали наук.-практ. круглого столу (м. Харків, 24 жовт. 2019 р.) / МВС України ; Харків. нац. ун-т внутр. справ, Фак. № 1 (з підготовки слідчих), Каф. кримінал. процесу та організації досуд. слідства. - Харків, 2019. - С. 42-45.Метою даної роботи є дослідження поняття (ознак), передумов, підстав, особливостей застосування та значення звільнення від кримінальної відповідальності у зв’язку з примиренням винного з потерпілим.The purpose of this work is to study the concept (signs), preconditions, grounds, peculiarities of application and significance of release from criminal liability in connection with the reconciliation of the perpetrator with the victim.Целью данной работы является исследование понятия (признаков), предпосылок, оснований, особенностей применения и значение освобождения от уголовной ответственности в связи с примирением виновного с потерпевшим
Invisibility in billiards
The question of invisibility for bodies with mirror surface is studied in the
framework of geometrical optics. We construct bodies that are invisible/have
zero resistance in two mutually orthogonal directions, and prove that there do
not exist bodies which are invisible/have zero resistance in all possible
directions of incidence
Resonance regimes of scattering by small bodies with impedance boundary conditions
The paper concerns scattering of plane waves by a bounded obstacle with
complex valued impedance boundary conditions. We study the spectrum of the
Neumann-to-Dirichlet operator for small wave numbers and long wave asymptotic
behavior of the solutions of the scattering problem. The study includes the
case when is an eigenvalue or a resonance. The transformation from the
impedance to the Dirichlet boundary condition as impedance grows is described.
A relation between poles and zeroes of the scattering matrix in the non-self
adjoint case is established. The results are applied to a problem of scattering
by an obstacle with a springy coating. The paper describes the dependence of
the impedance on the properties of the material, that is on forces due to the
deviation of the boundary of the obstacle from the equilibrium position
Application of Elements of Ergotherapy in Refusal Work with Persons who Have Been Suspected
Дослідження спрямоване на виявлення ступеню відновлення втрачених функцій та навиків самообслуговування у хворих з гострим порушенням мозкового кровообігу під впливом занять з ерготерапії.The research is directed to detect a degree recovery of lost functions and self-care skills in patients with acute violation of cerebral circulation under the influence of occupations on ergotherapy
Model of business process of management engineering company "Automation Group"
The aim of this study is to examine the problems of improving information security management organization, modeling business processes, detailed analysis and create a model of information technology management
Model of business process of management engineering company "Automation Group"
The aim of this study is to examine the problems of improving information security management organization, modeling business processes, detailed analysis and create a model of information technology management
Experimental research of the influence of static loads on the strength of polymercomposite materials
Structural insights into thrombolytic activity of destabilase from medicinal leech
Destabilase from the medical leech Hirudo medicinalis belongs to the family of i-type lysozymes. It has two different enzymatic activities: microbial cell walls destruction (muramidase activity), and dissolution of the stabilized fibrin (isopeptidase activity). Both activities are known to be inhibited by sodium chloride at near physiological concentrations, but the structural basis remains unknown. Here we present two crystal structures of destabilase, including a 1.1 Å-resolution structure in complex with sodium ion. Our structures reveal the location of sodium ion between Glu34/Asp46 residues, which were previously recognized as a glycosidase active site. While sodium coordination with these amino acids may explain inhibition of the muramidase activity, its influence on previously suggested Ser49/Lys58 isopeptidase activity dyad is unclear. We revise the Ser49/Lys58 hypothesis and compare sequences of i-type lysozymes with confirmed destabilase activity. We suggest that the general base for the isopeptidase activity is His112 rather than Lys58. pKa calculations of these amino acids, assessed through the 1 μs molecular dynamics simulation, confirm the hypothesis. Our findings highlight the ambiguity of destabilase catalytic residues identification and build foundations for further research of structure–activity relationship of isopeptidase activity as well as structure-based protein design for potential anticoagulant drug development.</p
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