BUS LOCATION AND ROUTE SYSTEM USING INTERNET OF THINGS

The fundamental point of undertaking is to plan a remote correspondence based transport position checking framework which is much helpful in operation. It is imperative to diminish traveler holding up time at transport stop, when clean time dining areas are obscure to traveler or traveler new in the city. To conquer the issue of travelers, the transport area and course route framework have the capacity effortlessly recover data about transport. Global positioning system, additionally furnishing clients with the most limited strolling course to closest bus stop.Â

Trastuzumab induced radiation recall dermatitis: an interesting case

Radiation recall dermatitis (RRD) is the appearance of skin reactions in previously irradiated skin which is triggered by the administration of certain drugs. Surgery, chemotherapy, and radiotherapy are the mainstay of treatment in breast cancer. RRD induced by trastuzumab has been rarely reported in India. This is a case report of a 56-year-old woman presented to the medical oncology outpatient department of our hospital with breast lump, and she was diagnosed to have human epidermal growth factor receptor 2 (HER-2/neu) positive invasive ductal carcinoma of left breast of stage T2N3cM0. She was treated with neoadjuvant chemotherapy, and she underwent modified radical mastectomy with axillary lymph node dissection. The treating oncologist was planned to start on adjuvant chemotherapy with injection trastuzumab for every four weeks, for 15 cycles. Patient received first dose of injection trastuzumab (450 mg) intravenously in the right (contralateral) arm and developed painful, swollen, erythematous blisters, and maculopapular rashes following the sharp linear borders of her previous radiation fields. She was reviewed by the medical oncologist and diagnosed as a rare case of RRD and treated with topical betamethasone cream. Causality assessment for RRD to trastuzumab was done using Naranjo and WHO-UMC scale and found to be in the category of probable and probable/ likely respectively

Dynamic Resource Allocation for Parallel Data Processing in Cloud Computing Environment

Dynamic resource allocation problem is one of the most challenging problems in the resource management problems. The dynamic resource allocation in cloud computing has attracted attention of the research community in the last few years. Many researchers around the world have come up with new ways of facing this challenge. Ad-hoc parallel data processing has emerged to be one of the killer applications for Infrastructure-as-a-Service (IaaS) cloud. Number of Cloud provider companies has started to include frameworks for parallel data processing in their product which making it easy for customers to access these services and to deploy their programs. The processing frameworks which are currently used have been designed for static and homogeneous cluster setups. So the allocated resources may be inadequate for large parts of the submitted tasks and unnecessarily increase processing cost and time. Again due to opaque nature of cloud, static allocation of resources is possible, but vice-versa in dynamic situations. The proposed new Generic data processing framework is intended to explicitly exploit the dynamic resource allocation in cloud for task scheduling and execution

Nivolumab-induced immune mediated eczematous dermatitis in patient with carcinoma of buccal mucosa

An elderly man undergoing treatment for carcinoma of left buccal mucosa experienced the appearance of skin lesions on his chest, both upper limbs, and both lower limbs after receiving the first cycle of nivolumab therapy. A biopsy report confirmed that the patient had eczematous dermatitis, which was believed to be induced by nivolumab. Patient received symptomatic treatment with Prednisolone, Clobetasol propionate and Fusidic acid. The Skin lesions improved, and subsequently Framycetin cream was recommended, resulting in no further recurrence of lesion. Clinicians should remain vigilant about development of T-cell activation-related skin disorders when administrating immune checkpoint inhibitors, such as nivolumab

Model and control for cooperative energy management

Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2010.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from student-submitted PDF version of thesis.Includes bibliographical references (p. 79-80).Proto/Amorphous Cooperative Energy Management (PACEM) aims to build and deploy a highly scalable system for smart power grids that will enable efficient demand shaping for small-user networks. Two key problems are to provide distributed control algorithm for efficient demand shaping and to provide an incentive structure to encourage both users and the electric power sector to opt-in to PACEM. In this thesis, I address the first problem by designing ColoredPower, a probabilistic control algorithm. I implemented and tested ColoredPower in MIT Proto, building on previous work in spatial computing. Simulations in Proto show that ColoredPower operates within 3% error and provides a stable dynamic response time on the order of minutes. To address the second problem, I provide a model for user and power company incentives in PACEM, in the form of the Colored Procurement Mechanism, which enables further work in optimal algorithmic mechanism design.by Vinayak V. Ranade.M.Eng

A single compartment simulation model of pharmacokinetics

For better understanding about derivation of various parameters related to pharmacokinetics, this model is developed. Animals or human volunteers are not used in this model but the principles used in pharmacokinetic studies in volunteers are incorporated. There is detailed description about setting of the model and derivation of various parameters step by step. An example is followed to illustrate the calculations involved. Possibilities of further extension of model to derive additional parameters and variations are discussed. The experience indicates that the model serves as a good demonstration to undergraduate students and a meaningful experiment for PG-students for learning and as a practical-examination exercise. The purpose of the article is to widen the use of this simple teaching tool at various centers

Critical illness‑related corticosteroid insufficiency in children: A single center, prospective, cohort study

Background: Although guidelines for diagnosis and management of critical illness‑related corticosteroid insufficiency (CIRCI) in adults are developed, there is a paucity of data on CIRCI in children. Objective: To study the incidence, risk factors, mechanism, and associations of CIRCI in children using adrenocorticotropic hormone (ACTH) stimulation test. Materials and Methods: Single‑center prospective cohort study was conducted in eight bedded pediatric intensive care unit of teaching hospital over a period of 1 year. Serum total cortisol concentration was measured in 110 critically ill children before and after stimulation with 250 μg ACTH. CIRCI was defined by post‑ACTH increment in serum cortisol ≤9 μg/dl. Children with and without CIRCI were compared. Results: Incidence of CIRCI was 38.2%. Children with CIRCI had higher median age (34 vs. 18 months), higher pediatric risk of mortality score (17.79±2.60 vs. 16.37±3.68), and significantly higher basal cortisol levels (27.37±11.64 vs. 22.02±7.26) (p=0.004) than those without CIRCI. There was a significantly higher (p=0.000) requirement of catecholamines (2.71±0.457 vs. 2.00±0.792) and higher additional fluid boluses (15.79±4.7 vs. 10.65±4.60) in children with CIRCI. However, duration of catecholamine use was not significantly different between two groups. The presence of CIRCI was not found to be an independent risk factor for mortality. For each additional use of catecholamine, the risk of CIRCI increased to 5.6 times; and for each extra fluid bolus, the risk increased to 1.2 times. Conclusion: CIRCI occurs in a wide spectrum of diseases in critically ill children associated with increased need for catecholamine and fluids. CIRCI is likely to be multifactorial in etiology and associated with high basal cortisol levels

HOW TO CONTAIN ETHICAL MISDEEDS AND CORRUPTION

ABSTRACT In this fast changing world, people are becoming power-centric. Their insatiable lust for power of all sorts and unending desires make them focus on short-run to acquire power by whatever means. Such people with limited rationality often forget to do what would be best for them and for others in the long-run. This article elaborates on factors, such as individual, organizational and environmental factors collectively responsible for the growing phenomenon of ethical misdeeds and corruption which is detrimental to peace equity, freedom and justice. It is firmly believed that there is need to launch frontal attack on corruption by initiating measures as suggested in this article to contain corruption thus enabling formation of an ethical society which is necessary for sustainability