23 research outputs found

    Speeding-up Scientific Knowledge Transfer and Improvement of Capabilities of emerging European National Metrology Institutes and Designated Institutes in the field of thermal measurements: Benefits and Impacts

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    Within the frame of a European project called Eura-Thermal, the general objective was to upgrade the regional metrological infrastructure (Bosnia & Herzegovina, Croatia, Ireland, Serbia...) with new capabilities, especially in the field of thermal measurements. This paper highlights the strategy used for improving in the short term, scientific knowledge transfer and the capabilities of different emerging institutes. Furthermore, as a main output, the impacts and benefit for Industry and for the end-users are also presented as examples. © 2018 Institute of Physics Publishing. All rights reserved.XXII World Congress of the International Measurement Confederation (IMEKO 2018

    Corrigendum to "European contribution to the study of ROS:A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162]

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    The European Cooperation in Science and Technology (COST) provides an ideal framework to establish multi-disciplinary research networks. COST Action BM1203 (EU-ROS) represents a consortium of researchers from different disciplines who are dedicated to providing new insights and tools for better understanding redox biology and medicine and, in the long run, to finding new therapeutic strategies to target dysregulated redox processes in various diseases. This report highlights the major achievements of EU-ROS as well as research updates and new perspectives arising from its members. The EU-ROS consortium comprised more than 140 active members who worked together for four years on the topics briefly described below. The formation of reactive oxygen and nitrogen species (RONS) is an established hallmark of our aerobic environment and metabolism but RONS also act as messengers via redox regulation of essential cellular processes. The fact that many diseases have been found to be associated with oxidative stress established the theory of oxidative stress as a trigger of diseases that can be corrected by antioxidant therapy. However, while experimental studies support this thesis, clinical studies still generate controversial results, due to complex pathophysiology of oxidative stress in humans. For future improvement of antioxidant therapy and better understanding of redox-associated disease progression detailed knowledge on the sources and targets of RONS formation and discrimination of their detrimental or beneficial roles is required. In order to advance this important area of biology and medicine, highly synergistic approaches combining a variety of diverse and contrasting disciplines are needed

    Significance of buried object orientation variation in their detection using thermography

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    Abstract Landmines are part of a complex system with variable characteristics that may change with time. If thermography is applied on such a system, the most significant characteristics of resulting thermograms is overcritical noise which has severely suppressed the application of thermography for landmine detection for humanitarian demining. The attempts to realise as much as possible of the thermography potential motivated concentrating onto sources of noise in buried objects thermograms, in particular onto variations in mine orientation relative to the soil normal. The experiments reported in this paper were performed in order to investigate the influence of angle between the local vertical axis and mine symmetry axis, the angle between the local vertical axis and soil surface normal, and the object depth. The influences are quantified and ranked through the statistically planned experiment. The strongest influence is the statistical interaction of depth and angles. According to the statistical test these two combinations are significant influences. The results indicate that the application of modern thermography in humanitarian demining is to be broadened by including the variations in mine orientation

    Methods of Fault Detection in Rolling Element Bearings

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    Proceedings of 7th BalkanTrib International Conference on Tribology BALKANTRIB 201

    Synthesis and evaluation of antibacterial and antioxidant activity of novel 2-phenyl-quinoline analogs derivatized at position 4 with aromatically substituted 4H-1,2,4-triazoles

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    A set of novel quinolone-triazole conjugates (12-31) were synthesized in three steps in good yields starting from 2-phenylquinoline-4-carboxylic acid. All the intermediates, as well as the final 1,2,4-triazolyl quinolines were fully characterized by their detailed spectral analysis utilizing different techniques such as IR, 1H NMR, 13C NMR, and finally mass spectrometry. All the synthesized compounds were evaluated in vitro for their potential antibacterial activity and their preliminary safety profile was assessed through cytotoxicity assay. Additionally, six selected conjugates were evaluated for their antioxidative properties on the basis of density functional theory calculations, using radical scavenging assay (DPPH) and cellular antioxidant assay. The reported results encourage further investigation of selected compounds and are shading light on their potential pharmacological use
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