242 research outputs found

    Calculation of Oil-saturated Sand Soils’ Heat Conductivity

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    Nowadays, there are significant heavy high-viscosity oil reserves in the Russian Federation with oil recovery coefficient not higher than 0.25-0.29 even with applying modern and efficient methods of oil fields development. Thermal methods are the most promising out of the existing ways of development, main disadvantage of which is large material costs, leading to the significant rise in the cost of extracted oil. Thus, creating more efficient thermal methods and improving the existing ones, is the task of great importance in oil production. One of the promising trends in enhancing thermal methods of oil recovery is the development of bottomhole electric steam generators. Compared to the traditional methods of thermal-steam formation treatment, which involve steam injection from surface, well electrothermal devices can reduce energy losses and improve the quality of steam injected into the formation. For successful and efficient organization of oil production and rational development of high-viscosity oil fields using well electrothermal equipment, it is necessary to take into account the pattern of heat propagation, both in the reservoir and in the surrounding space, including the top and bottom. One of the main values characterizing this process is the heat conductivity λ of oil-bearing rocks.  The article describes composition of typical oil-saturated sand soils, presents studies of heat and mass transfer in oil-saturated soils, reveals the effect of various parameters on the heat conductivity of a heterogeneous system, proposes a method for calculating the heat conductivity of oil-bearing soils by sequential reduction of a multicomponent system to a two-component system and proves the validity of the proposed approach by comparing acquired calculated dependencies and experimental data

    RKKY interactions in the regime of strong localization

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    We study the influence of strong nonmagnetic disorder on the Ruderman-Kittel-Kasuya-Yosida (RKKY) interactions between diluted magnetic moments in metals. We find that the probability distribution for the RKKY interactions assumes strongly non-Gaussian form featuring long tails. Since such distributions cannot be characterized by its moments, we define a \textit{typical} value of the interaction amplitude, which we find to be exponentially suppressed in presence of Anderson localization. Our results present a plausible and physically transparent picture describing how Anderson localization effectively eliminates the long range nature of the RKKY interactions.Comment: 6 pages, published versio

    Concepts and characteristics of the 'COST Reference Microplasma Jet'

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    Biomedical applications of non-equilibrium atmospheric pressure plasmas have attracted intense interest in the past few years. Many plasma sources of diverse design have been proposed for these applications, but the relationship between source characteristics and application performance is not well-understood, and indeed many sources are poorly characterized. This circumstance is an impediment to progress in application development. A reference source with well-understood and highly reproducible characteristics may be an important tool in this context. Researchers around the world should be able to compare the characteristics of their own sources and also their results with this device. In this paper, we describe such a reference source, developed from the simple and robust micro-scaled atmospheric pressure plasma jet (μ-APPJ) concept. This development occurred under the auspices of COST Action MP1101 'Biomedical Applications of Atmospheric Pressure Plasmas'. Gas contamination and power measurement are shown to be major causes of irreproducible results in earlier source designs. These problems are resolved in the reference source by refinement of the mechanical and electrical design and by specifying an operating protocol. These measures are shown to be absolutely necessary for reproducible operation. They include the integration of current and voltage probes into the jet. The usual combination of matching unit and power supply is replaced by an integrated LC power coupling circuit and a 5 W single frequency generator. The design specification and operating protocol for the reference source are being made freely available

    Identifying Neighborhoods of Coordinated Gene Expression and Metabolite Profiles

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    In this paper we investigate how metabolic network structure affects any coordination between transcript and metabolite profiles. To achieve this goal we conduct two complementary analyses focused on the metabolic response to stress. First, we investigate the general size of any relationship between metabolic network gene expression and metabolite profiles. We find that strongly correlated transcript-metabolite profiles are sustained over surprisingly long network distances away from any target metabolite. Secondly, we employ a novel pathway mining method to investigate the structure of this transcript-metabolite relationship. The objective of this method is to identify a minimum set of metabolites which are the target of significantly correlated gene expression pathways. The results reveal that in general, a global regulation signature targeting a small number of metabolites is responsible for a large scale metabolic response. However, our method also reveals pathway specific effects that can degrade this global regulation signature and complicates the observed coordination between transcript-metabolite profiles

    Corrigendum : Concepts and characteristics of the 'COST Reference Microplasma Jet'

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    ABSTRACT: Biomedical applications of non-equilibrium atmospheric pressure plasmas have attracted intense interest in the past few years. Many plasma sources of diverse design have been proposed for these applications, but the relationship between source characteristics and application performance is not well-understood, and indeed many sources are poorly characterized. This circumstance is an impediment to progress in application development. A reference source with well-understood and highly reproducible characteristics may be an important tool in this context. Researchers around the world should be able to compare the characteristics of their own sources and also their results with this device. In this paper, we describe such a reference source, developed from the simple and robust micro-scaled atmospheric pressure plasma jet (μ-APPJ) concept. This development occurred under the auspices of COST Action MP1101 'Biomedical Applications of Atmospheric Pressure Plasmas'. Gas contamination and power measurement are shown to be major causes of irreproducible results in earlier source designs. These problems are resolved in the reference source by refinement of the mechanical and electrical design and by specifying an operating protocol. These measures are shown to be absolutely necessary for reproducible operation. They include the integration of current and voltage probes into the jet. The usual combination of matching unit and power supply is replaced by an integrated LC power coupling circuit and a 5 W single frequency generator. The design specification and operating protocol for the reference source are being made freely available

    Propolis can potentialise the anti-adhesion activity of proanthocyanidins on uropathogenic Escherichia coli in the prevention of recurrent urinary tract infections

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    <p>Abstract</p> <p>Background</p> <p><it>Escherichia coli</it>, the main bacteria found in recurrent urinary tract infections (UTI), is now frequently resistant to several currently used antibiotic treatments making new solutions essential. In this study, we evaluated the association propolis and proanthocyanidins type A to reduce bacterial anti-adhesion activity of <it>E. coli </it>on urothelial cells.</p> <p>Results</p> <p>This first double-blind, randomized, cross-over human trial included 5 volunteers that followed 6 different regimens with or without variable doses of cranberry and propolis with a washout period of at least 1 week between each regimen. Urine samples were collected at 0 h, 4-6 h, 12 h and 24 h after cranberry plus propolis or placebo capsule consumption. In vivo urinary bacterial anti-adhesion activity was assessed with a bioassay (a human T24 epithelial cell-line assay) and an in vivo <it>Caenorhabditis elegans </it>model. HPLC-PDA-MS was used to detect propolis and cranberry compounds in urine. Bioassays indicated significant bacterial anti-adhesion activity in urine collected from volunteers who had consumed cranberry plus propolis powder compared to placebo (<it>p </it>< 0.001). This inhibition was clearly dose-dependent, increasing with the amount of PACs and propolis equivalents consumed in each regimen. Results suggested that propolis had an additional effect with PACs and prevent a bacterial anti-adhesion effect over 1 day. An in vivo model showed that the <it>E. coli </it>strain presented a reduced ability to kill <it>C. elegans </it>after their growth in urine samples of patients who took cranberry plus propolis capsules. HPLC confirmed that propolis is excreted in urine.</p> <p>Conclusions</p> <p>This study presents an alternative to prevent recurrent UTI. Administration of PACs plus propolis once daily offers some protection against bacterial adhesion, bacterial multiplication and virulence in the urinary tract, representing an interesting new strategy to prevent recurrent UTI.</p
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