A Perturbed Self-organizing Multiobjective Evolutionary Algorithm to solve Multiobjective TSP

Travelling Salesman Problem (TSP) is a very important NP-Hard problem getting focused more on these days. Having improvement on TSP, right now consider the multi-objective TSP (MOTSP), broadened occurrence of travelling salesman problem. Since TSP is NP-hard issue MOTSP is additionally a NP-hard issue. There are a lot of algorithms and methods to solve the MOTSP among which Multiobjective evolutionary algorithm based on decomposition is appropriate to solve it nowadays. This work presents a new algorithm which combines the Data Perturbation, Self-Organizing Map (SOM) and MOEA/D to solve the problem of MOTSP, named Perturbed Self-Organizing multiobjective Evolutionary Algorithm (P-SMEA). In P-SMEA Self-Organizing Map (SOM) is used extract neighborhood relationship information and with MOEA/D subproblems are generated and solved simultaneously to obtain the optimal solution. Data Perturbation is applied to avoid the local optima. So by using the P-SMEA, MOTSP can be handled efficiently. The experimental results show that P-SMEA outperforms MOEA/D and SMEA on a set of test instances

A serological study of leptospirosis in Chennai

Background: Leptospirosis is a zoonotic disease of mammals caused by serovars belonging to the spirocheate Leptospira interrogans. Commonly occurs in tropical and sub tropical regions.Methods: A total number of 2180 suspected cases were included in the study during the period April 2014 to June 2014. All the samples were subjected to macroscopic slide agglutination test (MSAT). Suspected leptospirosis cases (n=2180) in the Chennai city and its suburbs were clinically evaluated.Results: The most common presentation involved was specific signs and symptoms including fever, myalgia and headache (99%). Fever followed by jaundice and renal failure were observed in 3.74% cases. Fever followed by chills, skin rashes, cough, vomiting were observed in 2.43% cases. About 30% of the infected people were found in the age group of above 60 years. Female (57 %) were found predominantly infected when compared to male (43 %). Out of 2180 suspected cases 534 (32%) were found infected due to leptospirosis during the summer by MSAT method. (April ’14-June’14).Conclusions: This study shows leptospirosis found more common among female than male, probably due to occupational status of leptospirosis. Based on our study we suggest that senior age group people (age more than 60 years) are highly proven to this disease probably due to the less immunity factor

Hydrolysis of proteinaceous tannery solid waste for the production of extracellular acidic protease by Selenomonas ruminantium

The objective of this study was to produce protease from Selenomonas ruminantium using animal fleshing (ANFL), an untanned tannery solid waste as the sole protein source. Optimization of the minimal medium composition for the production of protease was carried out by a statistical approach using response surface methodology (RSM) which includes the variables such as NH4Cl, K2HPO4, KH2PO4 and NaCl. The isolate was found to produce maximum protease at pH 6 and at a temperature of about 40°C. Protease was purified 56 fold with a total yield of 28.14%. The enzyme was found to be monomeric having a molecular weight around 53 kDa. The purified enzyme was stable at a pH of about 4 revealing its acid protease nature and was also found to be stable up to 40°C. The enzyme was activated by divalent cations like Ca2+ and Mg2+ and inhibited by dithiothreitol (DTT), where the latter suggested its cysteine protease nature. The enzyme had good stability in the presence of non-ionic surfactants like tween 20, tween 40, tween 80 and triton X100 and also in the presence of solvents like methanol, ethanol and isopropanol. These characteristics reveal the potential of the enzyme for different industrial applications.Keywords: Acid protease, animal fleshing, optimization, response surface methodology (RSM), Selenomonas ruminantiu

Lymphocytic Mastitis with Fibroadenoma – A Case Report

Diabetic mastopathy is an uncommon fibrous tissue lesion of the breast which is usually seen in patients with longstanding type 1 diabetes mellitus. We report a case of diabetic mastopathy in an insulin dependent type 2 diabetes mellitus patient. 47-year-old postmenopausal woman, presented with two lumps, one firm mobile mass and another, a firm-hard mass in the upper inner quadrant of the left breast. Mammography and ultrasonography came out to be BIRADS III lesion. Fine-needle aspiration cytology [FNAC] was performed showing features of fibroadenoma with fibrocystic change. Histopathological examination and Immunohistochemistry studies revealed it to be fibroadenoma along with lymphocytic mastopathy. Keywords: Fibroadenoma, Lymphocytic mastitis, Mimicker, Diabete

Secure Biometric Authentication System Architecture Using Fingerprint Using FAR

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Anthropometric factors and breast cancer risk among urban and rural women in South India: a multicentric case–control study

Breast cancer (BC) incidence in India is approximately twice as high in urban women than in rural women, among whom we investigated the role of anthropometric factors and body size. The study was conducted at the Regional Cancer Centre, Trivandrum, and in three cancer hospitals in Chennai during 2002–2005. Histologically confirmed cases (n=1866) and age-matched controls (n=1873) were selected. Anthropometric factors were measured in standard ways. Information on body size at different periods of life was obtained using pictograms. Odds ratios (OR) of BC were estimated through logistic regression modelling. Proportion of women with body mass index (BMI)>25.0 kg/m2, waist size >85 cm and hip size >100 cm was significantly higher among urban than rural women. Risk was increased for waist size >85 cm (pre-menopausal: OR=1.24, 95% CI: 0.96–1.62; post-menopausal: 1.61, 95% CI: 1.22–2.12) and hip size >100 cm (pre-menopausal: OR=1.47, 95% CI: 1.05–2.06; post-menopausal 2.42, 95% CI: 1.72–3.41). Large body size at age 10 (OR=1.75, 95% CI: 1.01–3.03) and increased BMI (OR=1.33, 95% CI: 1.05–1.69 for 25.0–29.9 kg/m2 and OR=1.56, 95% CI: 1.03–2.35 for 30+ kg/m2) were associated with pre-menopausal BC risk. Our data support the hypotheses that increased anthropometric factors are risk factors of BC in India

Conceptual Framework on Workplace Deviance Behavior: A Review

This article aims to highlight the importance of organizational climate with both destructive and constructive deviance behaviour in different cultural setting with workplace as a common ground. First, we discuss the need for research in workplace deviance especially destructive and constructive deviance behaviour with the review of previous studies from deviance literature. Next, we present the importance of climate and culture with both destructive and constructive deviance by proposing relationship among them with the help of a framework. The presented theoretical framework can be useful for conducting future empirical research. Finally, we present the conclusion and future research in conducting cross-national research with respect to deviance

Approaches in biotechnological applications of natural polymers

Natural polymers, such as gums and mucilage, are biocompatible, cheap, easily available and non-toxic materials of native origin. These polymers are increasingly preferred over synthetic materials for industrial applications due to their intrinsic properties, as well as they are considered alternative sources of raw materials since they present characteristics of sustainability, biodegradability and biosafety. As definition, gums and mucilages are polysaccharides or complex carbohydrates consisting of one or more monosaccharides or their derivatives linked in bewildering variety of linkages and structures. Natural gums are considered polysaccharides naturally occurring in varieties of plant seeds and exudates, tree or shrub exudates, seaweed extracts, fungi, bacteria, and animal sources. Water-soluble gums, also known as hydrocolloids, are considered exudates and are pathological products; therefore, they do not form a part of cell wall. On the other hand, mucilages are part of cell and physiological products. It is important to highlight that gums represent the largest amounts of polymer materials derived from plants. Gums have enormously large and broad applications in both food and non-food industries, being commonly used as thickening, binding, emulsifying, suspending, stabilizing agents and matrices for drug release in pharmaceutical and cosmetic industries. In the food industry, their gelling properties and the ability to mold edible films and coatings are extensively studied. The use of gums depends on the intrinsic properties that they provide, often at costs below those of synthetic polymers. For upgrading the value of gums, they are being processed into various forms, including the most recent nanomaterials, for various biotechnological applications. Thus, the main natural polymers including galactomannans, cellulose, chitin, agar, carrageenan, alginate, cashew gum, pectin and starch, in addition to the current researches about them are reviewed in this article.. }To the Conselho Nacional de Desenvolvimento Cientfíico e Tecnológico (CNPq) for fellowships (LCBBC and MGCC) and the Coordenação de Aperfeiçoamento de Pessoal de Nvíel Superior (CAPES) (PBSA). This study was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit, the Project RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462) and COMPETE 2020 (POCI-01-0145-FEDER-006684) (JAT)