Compton scattering sequence reconstruction algorithm for the liquid xenon gamma-ray imaging telescope (LXeGRIT)

The Liquid Xenon Gamma-Ray Imaging Telescope (LXeGRIT) is a balloon born experiment sensitive to \g -rays in the energy band of 0.2-20 MeV. The main detector is a time projection chamber filled with high purity liquid xenon (LXeTPC), in which the three-dimensional location and energy deposit of individual \g -ray interactions are accurately measured in one homogeneous volume. To determine the \g -ray initial direction (Compton imaging), as well as to reject background, the correct sequence of interactions has to be determined. Here we report the development and optimization of an algorithm to reconstruct the Compton scattering sequence and show its performance on Monte Carlo events and LXeGRIT data.Comment: To appear in: Hard X-Ray, Gamma-Ray, and Neutron Detector Physics II, 2000; Proc. SPIE, vol. 4141; R.B. James & R.C. Schirato, ed

Spectroscopy and Imaging Performance of the Liquid Xenon Gamma-Ray Imaging Telescope (LXeGRIT)

LXeGRIT is a balloon-borne Compton telescope based on a liquid xenon time projection chamber (LXeTPC) for imaging cosmic \g-rays in the energy band of 0.2-20 MeV. The detector, with 400 cm$^2$ area and 7 cm drift gap, is filled with high purity LXe. Both ionization and scintillation light signals are detected to measure the energy deposits and the three spatial coordinates of individual \g -ray interactions within the sensitive volume. The TPC has been characterized with repeated measurements of its spectral and Compton imaging response to \g -rays from radioactive sources such as \na, \cs, \yt and Am-Be. The detector shows a linear response to \g -rays in the energy range 511 keV -4.4 MeV, with an energy resolution (FWHM) of \Delta E/E=8.8% \: \sqrt{1\MeV /E}. Compton imaging of \yt \g -ray events with two detected interactions is consistent with an angular resolution of $\sim$ 3 degrees (RMS) at 1.8 MeV.Comment: To appear in: Hard X-Ray, Gamma-Ray and Neutron Detector Physics XI, 2000; Proc. SPIE, vol. 4140; K.A. Flanagan & O.H. Siegmund, ed

An Ontology of Soil Properties and Processes

Assessing the Underworld (ATU) is a large interdisciplinary UK research project, which addresses challenges in integrated inter-asset maintenance. As assets on the surface of the ground (e.g. roads or pave- ments) and those buried under it (e.g. pipes and cables) are supported by the ground, the properties and processes of soil a ect the performance of these assets to a signi cant degree. In order to make integrated deci- sions, it is necessary to combine the knowledge and expertise in multiple areas, such as roads, soil, buried assets, sensing, etc. This requires an underpinning knowledge model, in the form of an ontology. Within this context, we present a new ontology for describing soil properties (e.g. soil strength) and processes (e.g. soil compaction), as well as how they a ect each other. This ontology can be used to express how the ground a ects and is a ected by assets buried under the ground or on the ground surface. The ontology is written in OWL 2 and openly available from the University of Leeds data repository: http://doi.org/10.5518/54

A new diagnostic algorithm for Burkitt and diffuse large B-cell lymphomas based on the expression of CSE1L and STAT3 and on MYC rearrangement predicts outcome

Background Aggressive mature B-cell non-Hodgkin's lymphomas (BCL) sharing features of Burkitt's lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL) (intermediate BL/DLBCL) but deviating with respect to one or more characteristics are increasingly recognized. The limited knowledge about these biologically heterogeneous lymphomas hampers their assignment to a known entity, raising incertitude about optimal treatment approaches. We therefore searched for discriminative, prognostic, and predictive factors for their better characterization. Patients and methods We analyzed 242 cytogenetically defined aggressive mature BCL for differential protein expression. Marker selection was based on recent gene-expression profile studies. Predictive models for diagnosis were established and validated by a different set of lymphomas. Results CSE1L- and inhibitor of DNA binding-3 (ID3)-overexpression was associated with the diagnosis of BL and signal transduction and transcription-3 (STAT3) with DLBCL (P<0.001 for all markers). All three markers were associated with patient outcome in DLBCL. A new algorithm discriminating BL from DLBCL emerged, including the expression of CSE1L, STAT3, and MYC translocation. This ‘new classifier' enabled the identification of patients with intermediate BL/DLBCL who benefited from intensive chemotherapy regimens. Conclusion The proposed algorithm, which is based on markers with reliable staining properties for routine diagnostics, represents a novel valid tool in separating BL from DLBCL. Most interestingly, it allows segregating intermediate BL/DLBCL into groups with different treatment requirement

Towards a liquid Argon TPC without evacuation: filling of a 6 m^3 vessel with argon gas from air to ppm impurities concentration through flushing

In this paper we present a successful experimental test of filling a volume of 6 m$^3$ with argon gas, starting from normal ambient air and reducing the impurities content down to few parts per million (ppm) oxygen equivalent. This level of contamination was directly monitored measuring the slow component of the scintillation light of the Ar gas, which is sensitive to {\it all} sources of impurities affecting directly the argon scintillation.Comment: 9 pages, 6 figures, to appear in Proc. 1st International Workshop towards the Giant Liquid Argon Charge Imaging Experiment (GLA2010), Tsukuba, March 201

Inter-cluster reactivity of Metallo-aromatic and anti-aromatic Compounds and Their Applications in Molecular Electronics: A Theoretical Investigation

Local reactivity descriptors such as the condensed local softness and Fukui function have been employed to investigate the inter-cluster reactivity of the metallo-aromatic (Al4Li- and Al4Na-) and anti-aromatic (Al4Li4 and Al4Na4) compounds. We use the concept of group softness and group Fukui function to study the strength of the nucleophilicity of the Al4 unit in these compounds. Our analysis shows that the trend of nucleophilicity of the Al4 unit in the above clusters is as follows; Al4Li- > Al4Na- > Al4Li4 > Al4Na 4 For the first time we have used the reactivity descriptors to show that these clusters can act as electron donating systems and thus can be used as a molecular cathode.Comment: 23 pages, 1 figure and 1 table of conten

Steps towards the hyperfine splitting measurement of the muonic hydrogen ground state: pulsed muon beam and detection system characterization

The high precision measurement of the hyperfine splitting of the muonic-hydrogen atom ground state with pulsed and intense muon beam requires careful technological choices both in the construction of a gas target and of the detectors. In June 2014, the pressurized gas target of the FAMU experiment was exposed to the low energy pulsed muon beam at the RIKEN RAL muon facility. The objectives of the test were the characterization of the target, the hodoscope and the X-ray detectors. The apparatus consisted of a beam hodoscope and X-rays detectors made with high purity Germanium and Lanthanum Bromide crystals. In this paper the experimental setup is described and the results of the detector characterization are presented.Comment: 22 pages, 14 figures, published and open access on JINS