1,047 research outputs found
Systematic trends in beta-delayed particle emitting nuclei: The case of beta-p-alpha emission from 21Mg
We have observed beta+-delayed alpha and p-alpha emission from the
proton-rich nucleus 21Mg produced at the ISOLDE facility at CERN. The
assignments were cross-checked with a time distribution analysis. This is the
third identified case of beta-p-alpha emission. We discuss the systematic of
beta-delayed particle emission decays, show that our observed decays fit
naturally into the existing pattern, and argue that the patterns are to a large
extent caused by odd-even effects.Comment: 6 pages, 5 figure
FORMULATION AND EVALUATION OF GLICLAZIDE NANOSPONGES
Objective: The objective of the present study was to develop and characterize an optimal stable nanosponges of Gliclazide (GLZ) by using the emulsion solvent diffusion method and aimed to increase its bioavailability and release the drug in sustained and controlled manner.
Methods: The GLZ nanosponge was prepared by emulsion solvent diffusion method using different drug-polymer ratios (1:1 to 1:5) Eudragit S100 is used as a polymer. Differential scanning calorimetry (DSC) and Fourier transform infrared spectroscopy (FTIR) estimated the compatibility of GLZ with polymer. All formulations evaluated for production yield, entrapment efficiency, in vitro drug release, scanning electron microscopy (SEM) and stability studies.
Results: The DSC and FTIR Studies revealed that no interaction between drug and polymer. The Production yield of all batches in the range of 73.8±0.30 to 85.6±0.32. Batch F3 showed the highest production yield, the entrapment efficiency of batch F3 70.6±0.77. The average particle size ranges from 303±2.36 to 680±2.50 nm. By the end of 10th hour F3 formulation shown highest drug release was found to be 94.40±1.12%. The release kinetics of the optimized formulation shows zero-order drug release. The stability study indicates no significant change in the in vitro dissolution profile of optimized formulation.
Conclusion: The results of various evaluation parameters, revealed that GLZ nanosponges would be possible alternative delivery systems to conventional formulation to improve its bioavailability, the emulsion solvent diffusion method is best method for preparation of nanosponges and release the drug in sustained and controlled manner
The topology of a discussion: the #occupy case
We analyse a large sample of the Twitter activity developed around the social
movement 'Occupy Wall Street' to study the complex interactions between the
human communication activity and the semantic content of a discussion. We use a
network approach based on the analysis of the bipartite graph @Users-#Hashtags
and of its projections: the 'semantic network', whose nodes are hashtags, and
the 'users interest network', whose nodes are users In the first instance, we
find out that discussion topics (#hashtags) present a high heterogeneity, with
the distinct role of the communication hubs where most the 'opinion traffic'
passes through. In the second case, the self-organization process of users
activity leads to the emergence of two classes of communicators: the
'professionals' and the 'amateurs'. Moreover the network presents a strong
community structure, based on the differentiation of the semantic topics, and a
high level of structural robustness when a certain set of topics are censored
and/or accounts are removed. Analysing the characteristics the @Users-#Hashtags
network we can distinguish three phases of the discussion about the movement.
Each phase corresponds to specific moment of the movement: from declaration of
intent, organisation and development and the final phase of political
reactions. Each phase is characterised by the presence of specific #hashtags in
the discussion. Keywords: Twitter, Network analysisComment: 13 pages, 9 figure
Microscopic description of the beta delayed deuteron emission from \bbox{^6}He
The beta delayed deuteron emission from He is studied in a dynamical
microscopic cluster model. This model gives a reasonably good description for
all the subsystems of He and Li in a coherent way, without any free
parameter. The beta decay transition probability to the Li ground state is
underestimated by a few percents. The theoretical beta delayed deuteron
spectrum is close to experiment but it is also underestimated by about a factor
1.7. We argue that, in spite of their different magnitudes, both
underestimations might have a common origin. The model confirms that the
neutron halo part of the He wave function plays a crucial role in quenching
the beta decay toward the + d channel.Comment: LATEX with REVTEX, Submitted to Phys. Rev. C, 11 pages, 3 figures
(not included) are available upon request. ATOMKI-93/
Experimental study of the collision 11Be + 64Zn around the Coulomb barrier
In this paper details of the experimental procedure and data analysis of the collision of 11Be +64Zn around the Coulomb barrier are described and discussed in the framework of different theoretical approaches. In a previous work, the elastic scattering angular distribution of the collisions 9 ,10Be +64Zn as well as the angular distribution for the quasielastic scattering and transfer/breakup cross sections for the 11Be +64Zn reaction were briefly reported. The suppression of the quasielastic angular distribution in the Coulomb-nuclear interference angular region observed in the collision of the 11Be halo nucleus with respect to the other two beryllium isotopes was interpreted as being caused by a long-range absorption owing to the long decay length of the 11Be wave function. In this paper, new continuum-discretized coupled-channel calculations of the 11Be +64Zn reaction are reported in the attempt to interpret the effect of coupling with the breakup channels on the measured cross sections. The calculations show that the observed suppression of the Coulomb-nuclear interference peak is caused by a combined effect of Coulomb and nuclear couplings to the breakup channels.INFN y Ministerio de Ciencia e Innovación (España) FPA2009-07653 FPA2009-07387 FPA2010-17142Comisión Europea 50606
Study of bound states in 12Be through low-energy 11Be(d,p)-transfer reactions
The bound states of 12Be have been studied through a 11Be(d,p)12Be transfer
reaction experiment in inverse kinematics. A 2.8 MeV/u beam of 11Be was
produced using the REX-ISOLDE facility at CERN. The outgoing protons were
detected with the T-REX silicon detector array. The MINIBALL germanium array
was used to detect gamma rays from the excited states in 12Be. The gamma-ray
detection enabled a clear identification of the four known bound states in
12Be, and each of the states has been studied individually. Differential cross
sections over a large angular range have been extracted. Spectroscopic factors
for each of the states have been determined from DWBA calculations and have
been compared to previous experimental and theoretical results
Indication of Anisotropy in Electromagnetic Propagation over Cosmological Distances
We report a systematic rotation of the plane of polarization of
electromagnetic radiation propagating over cosmological distances. The effect
is extracted independently from Faraday rotation, and found to be correlated
with the angular positions and distances to the sources. Monte Carlo analysis
yields probabilistic P-values of order 10^(-3) for this to occur as a
fluctuation. A fit yields a birefringence scale of order 10^(25) meters.
Dependence on redshift z rules out a local effect. Barring hidden systematic
bias in the data, the correlation indicates a new cosmological effect.Comment: 5 pages, 1 figure, ReVTeX. For more information, see
http://www.cc.rochester.edu/college/rtc/Borge/aniso.htm
Elastic Scattering for the 11Be+64Zn System Close to the Coulomb Barrier
The quasi-elastic scattering angular distribution of the collision 11Be + 64Zn was measured and compared with the elastic scattering angular distribution for its core, the 10Be nucleus on the same target. Optical model and continuum-discretized coupled-channel calculations of the 11Be+64Zn reaction were performed in order to interpret the effect of coupling with the break-up channels on the measured cross-sections
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