2,655 research outputs found

    Computerized structural mechanics for 1990's: Advanced aircraft needs

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    The needs for computerized structural mechanics (CSM) as seen from the standpoint of the aircraft industry are discussed. These needs are projected into the 1990's with special focus on the new advanced materials. Preliminary design/analysis, research, and detail design/analysis are identified as major areas. The role of local/global analyses in these different areas is discussed. The lessons learned in the past are used as a basis for the design of a CSM framework that could modify and consolidate existing technology and include future developments in a rational and useful way. A philosophy is stated, and a set of analyses needs driven by the emerging advanced composites is enumerated. The roles of NASA, the universities, and the industry are identified. Finally, a set of rational research targets is recommended based on both the new types of computers and the increased complexity the industry faces. Computerized structural mechanics should be more than new methods in structural mechanics and numerical analyses. It should be a set of engineering applications software products that combines innovations in structural mechanics, numerical analysis, data processing, search and display features, and recent hardware advances and is organized in a framework that directly supports the design process

    Solutions of the dispersion equation in the region of overlapping of zero-sound and particle-hole modes

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    In this paper the solutions of the zero-sound dispersion equation in the random phase approximation (RPA) are considered. The calculation of the damped zero-sound modes \omega_s(k) (complex frequency of excitation) in the nuclear matter is presented. The method is based on the analytical structure of the polarization operators \Pi(\omega,k). The solutions of two dispersion equations with \Pi(\omega,k) and with Re(\Pi(\omega,k)) are compared. It is shown that in the first case we obtain one-valued smooth solutions without "thumb-like" forms. Considering the giant resonances in the nuclei as zero-sound excitations we compare the experimental energy and escape width of the giant dipole resonance (GDR) in the nucleus A with \omega_s(k) taken at a definite wave vector k=k_A.Comment: 14 pages, 5 figures; revised versio

    Force balance and membrane shedding at the Red Blood Cell surface

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    During the aging of the red-blood cell, or under conditions of extreme echinocytosis, membrane is shed from the cell plasma membrane in the form of nano-vesicles. We propose that this process is the result of the self-adaptation of the membrane surface area to the elastic stress imposed by the spectrin cytoskeleton, via the local buckling of membrane under increasing cytoskeleton stiffness. This model introduces the concept of force balance as a regulatory process at the cell membrane, and quantitatively reproduces the rate of area loss in aging red-blood cells.Comment: 4 pages, 3 figure

    History of Plio-Pleistocene Climate in the Northeastern Atlantic, Deep Sea Drilling Project Hole 552A

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    DSDP Hole 552A, cored with the HPC on Hatton Drift, represents an almost complete and undisturbed sediment section spanning the late Neogene and Quaternary. Lithologic, faunal, isotopic, and paleomagnetic analyses indicate that the section represents the most complete deep sea record of climatic evolution hitherto recovered at high latitudes in the northern hemisphere. A glacial record of remarkable resolution for the late Pliocene and Pleistocene is provided by oxygen and carbon isotope ratios in benthic foraminifers. In the upper part of the section, the whole of the standard oxygen isotope record of the past million years is well preserved. The onset of ice-rafting and glacial-interglacial alternations occurs at about 2.4 m.y. ago

    Simvastatin pre-treatment improves survival and mitochondrial function in a 3-day fluid-resuscitated rat model of sepsis

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    Statins may offer protective effects in sepsis through anti-inflammatory, mitochondrial protection and other actions. We thus evaluated the effects of simvastatin on survival, organ and mitochondrial function, tissue and plasma ubiquinone levels and liver transcriptomics in a 3-day rat model of sepsis. Comparisons of rat plasma simvastatin and ubiquinone levels were made against levels sampled in blood from patients with acute lung injury (ALI) enrolled into a trial of statin therapy. Animals received simvastatin by gavage either pre- or post-induction of faecal peritonitis. Control septic animals received vehicle alone. Seventy-two-hour survival was significantly greater in statin pre-treated animals (43.7%) compared with their statin post-treated (12.5%) and control septic (25%) counterparts (P<0.05). Sepsis-induced biochemical derangements in liver and kidney improved with statin therapy, particularly when given pre-insult. Both simvastatin pre- and post-treatment prevented the fall in mitochondrial oxygen consumption in muscle fibres taken from septic animals at 24 h. This beneficial effect was paralleled by recovery of genes related to fatty acid metabolism. Simvastatin pre-treatment resulted in a significant decrease in myocardial ubiquinone. Patients with ALI had a marked variation in plasma simvastatin acid levels; however, their ubiquinone/low-density lipoprotein (LDL) cholesterol ratio did not differ regardless of whether they were receiving statin or placebo. In summary, despite protective effects seen with statin treatment given both pre- and post-insult, survival benefit was only seen with pre-treatment, reflecting experiences in patient studies

    Measuring light scattering and absorption in corals with Inverse Spectroscopic Optical Coherence Tomography (ISOCT): a new tool for non-invasive monitoring

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    Abstract: The success of reef-building corals for >200 million years has been dependent on the mutualistic interaction between the coral host and its photosynthetic endosymbiont dinoflagellates (family Symbiodiniaceae) that supply the coral host with nutrients and energy for growth and calcification. While multiple light scattering in coral tissue and skeleton significantly enhance the light microenvironment for Symbiodiniaceae, the mechanisms of light propagation in tissue and skeleton remain largely unknown due to a lack of technologies to measure the intrinsic optical properties of both compartments in live corals. Here we introduce ISOCT (inverse spectroscopic optical coherence tomography), a non-invasive approach to measure optical properties and three-dimensional morphology of living corals at micron- and nano-length scales, respectively, which are involved in the control of light propagation. ISOCT enables measurements of optical properties in the visible range and thus allows for characterization of the density of light harvesting pigments in coral. We used ISOCT to characterize the optical scattering coefficient (μs) of the coral skeleton and chlorophyll a concentration of live coral tissue. ISOCT further characterized the overall micro- and nano-morphology of live tissue by measuring differences in the sub-micron spatial mass density distribution (D) that vary throughout the tissue and skeleton and give rise to light scattering, and this enabled estimates of the spatial directionality of light scattering, i.e., the anisotropy coefficient, g. Thus, ISOCT enables imaging of coral nanoscale structures and allows for quantifying light scattering and pigment absorption in live corals. ISOCT could thus be developed into an important tool for rapid, non-invasive monitoring of coral health, growth and photophysiology with unprecedented spatial resolution

    The cold origin of the warm dust around epsilon Eridani

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    Context: The K2V star eps Eri hosts one known inner planet, an outer Kuiper belt analog, and an inner disk of warm dust. Spitzer/IRS measurements indicate that the warm dust is present at distances as close as a few AU from the star. Its origin is puzzling, since an "asteroid belt" that could produce this dust would be unstable because of the known inner planet. Aims: Here we test the hypothesis that the observed warm dust is generated by collisions in the outer belt and is transported inward by Poynting-Robertson (P-R) drag and strong stellar winds. Methods: We simulated a steady-state distribution of dust particles outside 10AU with a collisional code and in the inner region (r<10AU) with single-particle numerical integrations. By assuming homogeneous spherical dust grains composed of water ice and silicate, we calculated the thermal emission of the dust and compared it with observations. We investigated two different orbital configurations for the inner planet inferred from RV measurements, one with a highly eccentric orbit of e=0.7 and another one with a moderate one of e=0.25. We also produced a simulation without a planet. Results: Our models can reproduce the shape and magnitude of the observed SED from mid-IR to sub-mm wavelengths, as well as the Spitzer/MIPS radial brightness profiles. The best-fit dust composition includes both ice and silicates. The results are similar for the two possible planetary orbits and without a planet. Conclusions: The observed warm dust in the system can indeed stem from the outer belt and be transported inward by P-R and stellar wind drag. The inner planet has little effect on the distribution of dust, so that the planetary orbit could not be constrained. Reasonable agreement between the model and observations can only be achieved by relaxing the assumption of purely silicate dust and assuming a mixture of silicate and ice in comparable amounts.Comment: 9 pages, 9 figures, abstract abridge
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