Implementation of Beam Matching Concept for the New Installed Elekta Precise Treatment System Medical LINACs in Indonesia

A concept of radiation beam matching of some medical linear accelerators (LINACs) that have identical characteristics of the models, radiation quality, and multileaf collimator features may be implemented as long as the manufacturer provides complete specifications so that a Treatment Planning System (TPS) can be used for many beam-matched LINACs. This paper describes a preliminary study on the implementation of the beam matching concept for five units Elekta Precise Treatment System LINACs that have recently been installed in Indonesia. The beam matching criteria were based on the percentage depth dose (PDD) and beam profile for photon and electron beams. Dosimetry measurements were carried out by using an SNC 125 ionization chamber of 0.125 cm3 in volume, PTW Pinpoint 3D of  0.016 cm3 in volume, and PTW Farmer Chamber of 0.6 cm3 in volume. The results indicated that the PDD10 of 6 and 10 MV photon beams among installed five units LINACs have excellent compatibility each others with a maximum deviation of less than 0.4 %, while the maximum deviation for dose depth of 80 % (R80) for the electron beams with nominal energies of 4, 6, 8, 10, 15 and 18 MeV is 1 mm. The measurement results for the flatness profile were less than 6 %, and symmetry profiles were less than 3 %. It also outlines the determination of the absorbed dose to water under reference conditions. The results of the calibration of output doses show that the absorbed dose in the water was 1 cGy ≈ 1 MU. The data obtained from measurements for each LINAC conform with the requirements of the beam matching process set by the manufacturer

Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

In December 2016, a panel of experts in microbiology, nutrition and clinical research was convened by the International Scientific Association for Probiotics and Prebiotics to review the definition and scope of prebiotics. Consistent with the original embodiment of prebiotics, but aware of the latest scientific and clinical developments, the panel updated the definition of a prebiotic: a substrate that is selectively utilized by host microorganisms conferring a health benefit. This definition expands the concept of prebiotics to possibly include non-carbohydrate substances, applications to body sites other than the gastrointestinal tract, and diverse categories other than food. The requirement for selective microbiota-mediated mechanisms was retained. Beneficial health effects must be documented for a substance to be considered a prebiotic. The consensus definition applies also to prebiotics for use by animals, in which microbiota-focused strategies to maintain health and prevent disease is as relevant as for humans. Ultimately, the goal of this Consensus Statement is to engender appropriate use of the term ‘prebiotic’ by relevant stakeholders so that consistency and clarity can be achieved in research reports, product marketing and regulatory oversight of the category. To this end, we have reviewed several aspects of prebiotic science including its development, health benefits and legislation

Trials

BACKGROUND: The aim of this open-label, randomized controlled trial conducted in four African countries (Madagascar, Niger, Central African Republic, and Senegal) is to compare three strategies of renutrition for moderate acute malnutrition (MAM) in children based on modulation of the gut microbiota with enriched flours alone, enriched flours with prebiotics or enriched flours coupled with antibiotic treatment. METHODS: To be included, children aged between 6 months and 2 years are preselected based on mid-upper-arm circumference (MUAC) and are included based on a weight-for-height Z-score (WHZ) between - 3 and - 2 standard deviations (SD). As per current protocols, children receive renutrition treatment for 12 weeks and are assessed weekly to determine improvement. The primary endpoint is recovery, defined by a WHZ >/= - 1.5 SD after 12 weeks of treatment. Data collected include clinical and socioeconomic characteristics, side effects, compliance and tolerance to interventions. Metagenomic analysis of gut microbiota is conducted at inclusion, 3 months, and 6 months. The cognitive development of children is evaluated in Senegal using only the Developmental Milestones Checklist II (DMC II) questionnaire at inclusion and at 3, 6, and 9 months. The data will be correlated with renutrition efficacy and metagenomic data. DISCUSSION: This study will provide new insights for the treatment of MAM, as well as original data on the modulation of gut microbiota during the renutrition process to support (or not) the microbiota hypothesis of malnutrition. TRIAL REGISTRATION: ClinicalTrials.gov, ID: NCT03474276 Last update 28 May 2018

Oxygen Vacancy-rich Mesoporous Silica KCC-1 for CO2 Methanation

Mesoporous silica KCC-1 was successfully synthesized by microemulsion system coupled with microwave-assisted hydrothermal method. Mesoporous silica KCC-1 exhibited spherical morphology surrounded with dendritic fiber with the particle size of 200–400 nm and BET surface area of 773 m2/g. Mesoporous silica KCC-1 has significantly higher number of basicity and oxygen vacancy than those of MCM-41 and SiO2 which directly correlated with the catalytic performance of the catalyst. The activity of mesoporous silica KCC-1 in CO2 methanation is five-fold higher than MCM-41 with the yield of CH4 reached 38.9% at 723 K

Pengembangan Sistem Informasi Berbasis Android untuk Meningkatkan Pelayanan di Dinas Kependudukan dan Catatan Sipil

The Department of Population and Civil Registration is one of the public service institutions that includes recording and publishing services that aim to record data from each resident as completely as possible and therefore provide true certainty about events or events that have been experienced by residents. Meanwhile, the services provided by the Department of Population and Civil Registration are birth certificates for babies aged 0-60 days, making Family Cards (KK) and printing e-KTPs which are currently busy in Indonesia

Enhanced hydrogen-assisted cracking of 1,3,5-triisopropylbenzene over fibrous silica ZSM-5: Influence of co-surfactant during synthesis

In this study, unique fibrous silica ZSM-5 was successfully synthesized by using three type of alcohol possessing different alkyl-chain length as the co-surfactant. The effect of diverse co-surfactant was observed in the changes of physical properties, such as crystallinity, inter-dendrimer distances and pore properties. According to the IR and temperature programmed desorption of ammonia (NH3-TPD) analyses, all catalysts exhibited different acid strengths which could be triggered by the different amount of additional silica species. All catalysts exhibited high catalytic performance in the hydrocracking of 1,3,5-triisopropylbenzene due to the absence of diffusion limitation. However, FZSM5C3 exhibited the highest catalytic activity which corresponded to its high number of Brønsted acid sites. It was observed that different length of co-surfactant alkyl-chain has resulted in different degree of oil penetration into the microemulsion system which subsequently triggered in various inter-dendrimer distances and amount of incorporated silica species. Hence, the altered physicochemical properties led to the difference in catalytic performance due to the presence of different number of Brønsted acid sites

Development of Play Model: Efforts to Improve Basic Movement Skills for Elementary School Students

Basic movement skill is important in performing movements in any sport activities. Having good essential movement skills will make it easy for someone to do sports. One effort that should be possible is through the development of a play model. The purpose of this study was to develop a play model and the the effectiveness of a play model on basic movement skills. Research and development with Analyze Design Develop Implementation and Evaluation (ADDIE) was employed to develop play models. The play model was designed in such a way through the stages of identification, game user targets, learning outcome, game time, overall goals, game variations and the final part of the game. This study was participated by third grade elementary students with 84 students in total with an average age of boys (± 9.5 years), and girls (± 9.7 years). The treatment was carried out 16 times for twice a week during class break. This study used three instruments, namely student perception questionnaire, knowledge test and the Test of Gross Motor Development (TGMD-2), with locomotor test items and object skills. This study had produced a play model product and shown a significant effect of developing a playing model on improving students' basic movement skill