Analysis of Game Actions and Performance in Young Soccer Players: A Study Using Sequential Analysis

The objective of this research is to analyze the performance of actions in a reduced game situation in a sample of young soccer players. This is a game format in which possession of the ball has to be maintained. The sample consisted of 85 young players aged between 12 and 16 years, observing a total of 58 reduced games and using an analysis instrument called the Game Performance Assessment Instrument (GPAI). The essential data quality analyses are carried out, including the use of correlation indexes, Cohen’s Kappa and the Phi index for intra- and inter-observer reliability. Generalizability and invariance analyses are also performed to estimate the reliability, validity and precision of the numerical structure and its generalizability to other samples or populations with similar distributions. An observational design of nomothetic, punctual and multidimensional types is used, and subsequently, a sequential analysis of the game actions is carried out from the observations. The results show significant relationships between decision-making behaviors (adequate and inadequate) and technical execution behaviors (adequate and inadequate). The findings have highlighted a clear relationship of interdependence between technical execution and decision making. This information is very useful for the design and planning of training oriented to the optimization of sport performance in soccer.Partial funding for open access charge: Universidad de Málag

Diseño y validación de una herramienta de observación para porteros en balonmano playa

El objetivo de esta investigación fue crear un instrumento de observación en el contexto del balonmano playa para analizar las acciones del portero ante los lanzamientos de los atacantes. La herramienta ha sido diseñada ad hocmediante un sistema mixto de formatos de campo y sistema de categorías exhaustivas y mutuamente excluyentes (E/ME). Está constituida por 11 criterios y 85 categorías, destacando entre ellas el jugador que lanza, el tipo de lanzamiento, la acción defensiva realizada para dificultar ese lanzamiento y la acción del portero para intentar repelerlo. Se ha realizado un análisis de Calidad del Dato y un análisis de Generalizabilidad, se ha realizado un procedimiento de concordancia consensuada. Además, se han estimado los coeficientes de correlación Pearson, Spearman, Tau b de Kendall y el índice Kappa de Cohen. Los resultados han mostrado índices adecuados de correlación (≤ 0,936) y Kappa de Cohen (≤ 0,906). Los resultados obtenidos en el análisis de Generalizabilidad son también excelentes, resultando unos coeficientes G relativo y G absoluto de 0,985, en la concordancia interobservador, y de 0.998, en la concordancia intraobserbador. En conjunto, los datos presentados en este trabajo ponen de relieve una elevada validez, precisión y fiabilidad de las observaciones efectuadas con la herramienta analizada

re-habitar El Carmen : Un proyecto sobre patrimonio contemporáneo

El proyecto _re-HABITAR suponía para el propio proceder de la institución un avance más allá del reconocimiento, registro, inventario o protección patrimonial de la arquitectura del siglo XX y del Movimiento Moderno para posicionarse en la acción preventiva y conservativa de ese legado contemporáneo. Para ello, la praxis patrimonial se aferraba a un modelo: el de la vivienda social en España en la segunda mitad del siglo XX; a un caso concreto: el de la barriada de Nuestra Señora del Carmen (Recasens Méndez-Queipo de Llano, 1958); y a un requisito fundamental: analizar un objeto vivo y en uso, aún con la presencia de quienes lo vivieron y usaron desde su origen

Long-Term Real-World Effectiveness and Safety of Ustekinumab in Crohn’s Disease Patients: The SUSTAIN Study

Background Large real-world-evidence studies are required to confirm the durability of response, effectiveness, and safety of ustekinumab in Crohn’s disease (CD) patients in real-world clinical practice. Methods A retrospective, multicentre study was conducted in Spain in patients with active CD who had received ≥1 intravenous dose of ustekinumab for ≥6 months. Primary outcome was ustekinumab retention rate; secondary outcomes were to identify predictive factors for drug retention, short-term remission (week 16), loss of response and predictive factors for short-term efficacy and loss of response, and ustekinumab safety. Results A total of 463 patients were included. Mean baseline Harvey-Bradshaw Index was 8.4. A total of 447 (96.5%) patients had received prior biologic therapy, 141 (30.5%) of whom had received ≥3 agents. In addition, 35.2% received concomitant immunosuppressants, and 47.1% had ≥1 abdominal surgery. At week 16, 56% had remission, 70% had response, and 26.1% required dose escalation or intensification; of these, 24.8% did not subsequently reduce dose. After a median follow-up of 15 months, 356 (77%) patients continued treatment. The incidence rate of ustekinumab discontinuation was 18% per patient-year of follow-up. Previous intestinal surgery and concomitant steroid treatment were associated with higher risk of ustekinumab discontinuation, while a maintenance schedule every 12 weeks had a lower risk; neither concomitant immunosuppressants nor the number of previous biologics were associated with ustekinumab discontinuation risk. Fifty adverse events were reported in 39 (8.4%) patients; 4 of them were severe (2 infections, 1 malignancy, and 1 fever). Conclusions Ustekinumab is effective and safe as short- and long-term treatment in a refractory cohort of CD patients in real-world clinical practice

Using Interpretable Machine Learning to Identify Baseline Predictive Factors of Remission and Drug Durability in Crohn’s Disease Patients on Ustekinumab

Ustekinumab has shown efficacy in Crohn's Disease (CD) patients. To identify patient profiles of those who benefit the most from this treatment would help to position this drug in the therapeutic paradigm of CD and generate hypotheses for future trials. The objective of this analysis was to determine whether baseline patient characteristics are predictive of remission and the drug durability of ustekinumab, and whether its positioning with respect to prior use of biologics has a significant effect after correcting for disease severity and phenotype at baseline using interpretable machine learning. Patients' data from SUSTAIN, a retrospective multicenter single-arm cohort study, were used. Disease phenotype, baseline laboratory data, and prior treatment characteristics were documented. Clinical remission was defined as the Harvey Bradshaw Index <= 4 and was tracked longitudinally. Drug durability was defined as the time until a patient discontinued treatment. A total of 439 participants from 60 centers were included and a total of 20 baseline covariates considered. Less exposure to previous biologics had a positive effect on remission, even after controlling for baseline disease severity using a non-linear, additive, multivariable model. Additionally, age, body mass index, and fecal calprotectin at baseline were found to be statistically significant as independent negative risk factors for both remission and drug survival, with further risk factors identified for remission

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

PhDAY 2020 -FOO (Facultad de Óptica y Optometría)

Por cuarto año consecutivo los doctorandos de la Facultad de Óptica y Optometría de la Universidad Complutense de Madrid cuentan con un congreso propio organizado por y para ellos, el 4º PhDAY- FOO. Se trata de un congreso gratuito abierto en la que estos jóvenes científicos podrán presentar sus investigaciones al resto de sus compañeros predoctorales y a toda la comunidad universitaria que quiera disfrutar de este evento. Apunta en tu agenda: el 15 de octubre de 2020. En esta ocasión será un Congreso On-line para evitar que la incertidumbre asociada a la pandemia Covid-19 pudiera condicionar su celebración

Estudo das acções do porteiro no andebol de praia através da análise das coordenadas polares: diferenças por género

The objective of this research was to analyze the behaviors of the goalkeeper in beach handball. To do this, and discriminating by gender, on the one hand, an analysis of polar coordinates was made using as focal behaviors those related to the end of the attack, the two-points goal and the save of the goalkeeper; and on the other, which related to the finalization of the two specific players more relevant in the positional attack, the specialist and the pivot. A total of 12 sessions were observed with the HOISAN computer software, using an ad hoc designed tool with 11 criteria and 85 categories. The model of observation used was punctual, multidimensional and nomothetic. The results obtained showed differences between the flow of behaviours that are significantly linked in the male category compared to the female category. In both categories has coincided that the performance of the goalkeeper is decisive to finish winning the match. However, in male category, a greater participation of the goalkeepers has been observed in the construction of the fastbreak, as well as a linkage between the defense and the effectiveness of their actions. In addition, there are different ways of acting in both categories face the different shots of the opposing teamEl objetivo de esta investigación fue analizar las conductas del portero en balonmano playa. Para ello, y diferenciando por género, por un lado, se realizó un análisis de coordenadas polares utilizando como conductas focales las relacionadas con la finalización del ataque, el gol de valor doble y la parada del portero; y por otro las que se refieren a la finalización de los dos puestos específicos más relevantes en el ataque posicional, el especialista y el pivote. Se realizaron un total de 12 sesiones de observación con el software informático HOISAN, utilizándose una herramienta diseñada ad hocde 11 criterios y 85 categorías. El diseño observacional utilizado fue puntual, multidimensional y nomotético. Los resultados obtenidos mostraron relaciones significativas y diferenciadas para las categorías masculina y femenina. En ambos casos ha coincidido que la actuación del portero es determinante para acabar ganando un partido. Sin embargo, en categoría masculina se ha observado una mayor participación en la construcción del contraataque posterior, así como una vinculación entre la ayuda de los defensas y la eficacia de sus acciones. Además, se han evidenciado formas diferentes de actuar en ambas categorías ante los distintos lanzadores del equipo contrario.O objetivo deste trabalho foi analisar os comportamentos do goleiro em andebol praia. Para fazer isso, e discriminar por sexo, por um lado, realizou-se uma análise de coordenadas polares usando como ponto focal os comportamentos relacionados ao final do ataque, a meta de dois pontos e a paragem do goleiro; e por outro lado, as relativas à conclusão dos dois lugares específicos mais relevantes no ataque posicional, o especialista e o pivô. Um total de 12 sessões de observação com o software HOISAN, usando uma ferramenta numa base ad hoc de 11 critérios e 85 categorias. O modelo observacional usado foi pontual, multidimensional y nomotetico. Os resultados mostram relações significativas e diferenciadas para as categorias masculino e feminino. Em ambos os casos, coincidiu que o desempenho do goleiro é decisiva para terminar o jogo ganhando. No entanto, na categoria masculino, tem havido uma maior participação na construção da contra-ataque posterior, bem como uma articulação entre os defesas e a eficácia de suas ações. Além disso, há diferentes maneiras de atuar em ambas as categorias para os diferentes lançadores da equipa adversária

Estudo das ações do guarda redes de andebol de praia através da análise de coordenadas polares: diferenças por sexo

El objetivo de esta investigación fue analizar las acciones del portero en balonmano playa. Se realizó un análisis de coordenadas polares utilizando como conductas focales las que se refieren ala finalización del ataque y a la finalización de los dos puestos específicos más relevantes en el ataque posicional, diferenciando por categorías. Se realizaron un total de 12 sesiones de observación con el software informático HOISAN, utilizándose una herramienta diseñada ad hocde 11 criterios y 85 categorías. El diseño observacional utilizado fue puntual, multidimensional y nomotético. Los resultados obtenidos mostraron relaciones significativas y diferenciadas para las categorías masculina y femenina. En ambos casos ha coincidido que la actuación del portero es determinante para acabar ganando un partido. Sin embargo, en categoría masculina se ha observado una mayor participación en la construcción del contraataque posterior. Además, se han evidenciado formas diferentes de actuar en ambas categorías.ABSTRACT: The objective of this research was to analyze the performance of the goalkeeper in beach handball. An analysis of polar coordinates was made using asfocal behaviors those related to the end of the attack and to the finalization of the two specific players more relevant in the positional attack, discriminating by gender. A total of 12 sessions were observed with the HOISAN computer software, using an ad hoc designed tool with 11 criteria and 85 categories. The model of observation used was punctual, multidimensional and nomothetic. The results obtained showed differences between the flow of behaviours that are significantly linked in the male category compared to the female category. In both categories has coincided that the performance of the goalkeeper is decisive to finish winning the match. However, in male category, a greater participation of the goalkeepers hasbeen observed in the construction of the fastbreak. In addition, there are different ways of acting in both categories.RESUMO: O objectivo desta investigação foi analisar as açõesdo guarda redes de andebol de praia. Para ele, e diferenciando por género, por um lado, realizou-se uma análise de coordenadas polares utilizando como condutas focais as relacionadas com a finalização do ataque e as que se referem à finalização dos postos específicos mais relevantes no ataque posicional. Realizaram-se um total de 12 sessões de obvervação com o software informático HOISAN, utilizando uma ferramenta desenhada ad hoc de 11 critérios e 85 categorias. O desenho observacional utilizado foi pontual, multidimensionale nomotético. Os resultados obtidos mostraram uma relação significativa e diferenciada para as categorias masculina e feminina. Em ambos os casos coincidiu que a actuação do guarda redes é determinante para ganhar o jogo. Porém, na categoria masculina observou-se uma maior participação na construção do contra-ataque posterior. Também se evidenciou formas diferentes de actuar em ambas as categorías

Elaboração e validação de um instrumento de observação para guarda redes de andebol de praia

Los objetivos de esta investigación fueron crear un instrumento de observación para analizar las acciones del portero en balonmano playa y determinar la fiabilidad de los observadores, valorando la bondad de las categorías y estimando el número mínimo de sesiones necesarias para generalizar con precisión. La herramienta ha sido diseñada ad hocmediante un sistema mixto de formato de campo y sistema de categorías, exhaustivas y mutuamente excluyentes (E/ME). Está constituida por 11 criterios y 85 categorías. Los resultados han mostrado índices adecuados de correlación (≤ 0,936) y Kappa de Cohen (≤ 0,906). Los resultados obtenidos en el análisis de Generalizabilidad son también excelentes, resultando unos coeficientes G relativo y G absoluto de 0,985, en el acuerdo interobservador, y de 0,998, para el acuerdo intraobservador. En conjunto, los resultados presentados en este trabajo ponen de relieve una elevada validez, precisión y fiabilidad de las observaciones efectuadas con la herramienta analizada.ABSTRACT: The objectives of this research were to create an instrument of observation to analyze the actions of the goalkeeper in handball beach and determine the reliability of the observers, assessing the goodness of the categories and estimating the minimum number of sessions necessary to generalize with precision. The tool ad hoc has been designed using a mixed system of field format and a system of categories, exhaustive and mutually exclusive (E / ME). It is made up of 11 criteria and 85 categories. The results have shown adequate correlation rates (≤ 0,936) and Cohen's Kappa (≤ 0,906). The results obtained in the Generalizability analysis are also excellent, resulting in relative G coefficients and absolute G of 0,985, in the interobserver agreement, and 0.998, for the intraobserver agreement. Overall, the results presented in this work highlight the high validity, accuracy and reliability of the observations made with the tool analyzed.RESUMO: Os objectivos deste trabalho foram a criação de um instrumento de observação para analisar as acções do guarda redes de andebol de praia e determinar a fiabilidade dos observadores, valorizando a bondade das categorias e estimar o número mínimo de sessões necessárias para generalizar com precisão. A ferramenta foi desenhada com base ad hocmediante um sistema misto de formato de campo e sistema de categorias,exaustivas e mutuamente exclusivas (E/ME). Ela é composta por 11 critérios e 85 categorias.Os resultados obtidos demonstram índices adequados de relação (≤0,936) e Kappa de Cohen(≤0,906). Os resultados obtidos na análise da generalização são excelentes também, resultando coeficientes G relativo e G absoluto de 0,985, no acordo interobservador, e de 0,998 para o acordo inter-observador. De maneira geral, os resultados apresentados neste trabalho revelam uma alta validade, precisão e fiabilidade das observações efectuadas com esta ferramente analizad