68 research outputs found
Connection between completion of weight loss program and self efficacy in obese people
Diplomová práce se zabývá souvislostí mezi absolvováním redukčního kurzu a vnímanou osobní účinností u osob s obezitou. Teoretická část práce zabývá tématem obezity, jejího výskytu a oblastí spojených s její léčbou. Dále je popsán koncept vnímané osobní účinnosti, jeho kontexty s obezitou a pohybovou aktivností a koncept obecné vnímané účinnosti. Empirická část práce se zabývá popsáním pohybové aktivnosti u respondentů s obezitou a změnami vnímané osobní účinnosti v oblasti pohybu a obecné vnímané účinnosti v kontextu absolvování redukčního kurzu u respondentů s obezitou. Pro zmapování pohybové aktivnosti a ověření souvislosti mezi vnímanou osobní účinností v oblasti pohybových aktivit a absolvování redukčního kurzu byly vytvořeny vlastní dotazníky. Pro zkoumání souvislosti mezi obecnou vnímanou účinností a absolvováním redukčního kurzu byl použit inventář Obecné vlastní efektivity. Data byla sbírána v redukčních kurzech pořádaných organizací STOB. Sběr dat proběhl vždy na začátku a na konci jednotlivých kurzů. K ověření hypotéz byl použit párový t- test. U respondentů byla zjištěna nedostatečná frekvence pohybových aktivit. Mezi obecnou vnímanou účinností a absolvováním redukčního kurzu byl signifikantně významný rozdíl. Naopak nebyl nalezen signifikantně významný rozdíl mezi absolvováním kurzu a...The thesis deals with connections between completion of reduced course and self-efficacy of obese people. The theoretical part deals with definition of obesity, its prevalence and aspects of its treatment. A chapter of the theoretical part focuses on self-efficacy and its connections to obesity and physical activity. The last part is about general self-efficacy. The empirical part describes physical activity of obese respondents, changes in their physical activity self-efficacy and their general self-efficacy after completion of reduced course. The questionnaires about the level of physical activity and physical activity self-efficacy were created by author of the thesis. General self-efficacy was measured by General self-efficacy scale. Data were obtained in the first and last lesson of reduced courses. A paired-samples t-test was conducted to compare changes in both areas of self-efficacy. It has been found that frequency of respondents physical activity was insufficient. The results suggest that connection between completion of reduced course and general self-efficacy exist. On the other hand there was not significant difference between individual's physical self-efficacy before reduced course and after its completion. Keywords: obesity, self-efficacy, physical activity self-efficacy, general...Katedra psychologieDepartment of PsychologyFaculty of ArtsFilozofická fakult
Dissolution testing of tablets containing theophylline and mixtures of two types of calcium hydrogen phosphates and microcrystalline cellulose
Univerzita Karlova v Praze, Farmaceutická fakulta v Hradci Králové Katedra farmaceutické technologie Školitel: PharmDr. Pavel Ondrejček, Ph.D. Posluchač: Kateřina Vávrová Název diplomové práce: Hodnocení disoluce tablet obsahujících theofylin a směsi dvou typů hydrogenfosforečnanu vápenatého a mikrokrystalické celulosy Cílem této práce bylo zhodnocení disoluce tablet obsahujících theofylin, mikrokrystalickou celulosu a jednoho ze dvou typů hydrogenfosforečnanu vápenatého. Byl sledován vliv složení tabletoviny na disoluci tablet. Tablety byly slisovány ze směsí, které obsahovaly mikrokrystalickou celulosu, hydrogenfosforečnan vápenatý anhydrát a dihydrát. Tyto látky byly použity jako plniva. Připravené směsi obsahovaly theofylin jako modelovou účinnou látku a jako kluznou látku stearan hořečnatý. Následně byly provedeny disoluční testy. Při testech byla využita košíčková metoda. Jako disoluční médium byla použita 0,1M kyselina chlorovodíková. Z výsledků této práce jsme došli k závěrům, že jsme schopni ovlivňovat celkové množství uvolňovaného theofylinu a jeho rychlost uvolňování různým poměrem mikrokrystalické celulosy a jednoho ze dvou typů hydrogenfosforečnanu vápenatého. Nejrychleji se theofylin uvolňoval z tablet, které obsahovaly vysoký podíl mikrokrystalické celulosy. S klesající koncentrací...Charles University in Prague, Faculty of Pharmacy in Hradci Králové Department of Pharmaceutical technology Consultant: PharmDr. Pavel Ondrejček, Ph.D. Student: Kateřina Vávrová Title of Thesis: Dissolution testing of tablets containing theophylline and mixtures of two types of calcium hydrogen phosphates and microcrystalline cellulose The aim of this thesis was the dissolution testing of tablets containing theophylline, the mixture of two dicalcium phosphate types and microcrystalline cellulose. The influence of tablet composition on the dissolution profiles was evaluated. The tablets were prepared from the mixtures containing microcrystalline cellulose, dicalcium phosphate anhydrous and dihydrate. These substances were used as fillers. Prepared mixtures contained theophylline as a model active ingredient and magnesium stearate as lubricant. Afterwards, the dissolution tests were done. For these tests, the basket method was utilized. As a dissolution medium the 0,1M hydrochloric acid solution was used. From the results of this experiment we concluded that we can influence the total amount of released theophylline and the speed of its release by the different ratio of microcrystalline cellulose and one of dicalcium phosphate types. The fastest theophylline dissolution was in tablets with high...Katedra farmaceutické technologieDepartment of Pharmaceutical TechnologyFaculty of Pharmacy in Hradec KrálovéFarmaceutická fakulta v Hradci Králov
TSLP is a direct trigger for T cell migration in filaggrin-deficient skin equivalents
Mutations in the gene encoding for filaggrin (FLG) are major predisposing
factors for atopic dermatitis (AD). Besides genetic predisposition,
immunological dysregulations considerably contribute to its pathophysiology.
For example, thymic stromal lymphopoietin (TSLP) is highly expressed in
lesional atopic skin and significantly contributes to the pathogenesis of AD
by activating dendritic cells that then initiate downstream effects on, for
example, T cells. However, little is known about the direct interplay between
TSLP, filaggrin-deficient skin and other immune cells such as T lymphocytes.
In the present study, FLG knockdown skin equivalents, characterised by
intrinsically high TSLP levels, were exposed to activated CD4+ T cells. T cell
exposure resulted in an inflammatory phenotype of the skin equivalents.
Furthermore, a distinct shift from a Th1/Th17 to a Th2/Th22 profile was
observed following exposure of T cells to filaggrin-deficient skin
equivalents. Interestingly, TSLP directly stimulated T cell migration
exclusively in filaggrin-deficient skin equivalents even in the absence of
dendritic cells, indicating a hitherto unknown role of TSLP in the
pathogenesis of AD
Problematika veřejné správy v oblasti živnostenského podnikání (se zaměřením na město a okres Karviná)
Import 20/04/2006Prezenční výpůjčkaVŠB - Technická univerzita Ostrava. Ekonomická fakulta. Katedra (153) veřejné ekonomik
Dangerous substances in electrical apparatus
The diploma thesis deals with the influence of dangerous substances in electric aparatus on environment and also on human. The aim of this diploma thesis is to describe toxicological characteristics of dangerous substances in electric apparaus and to find out people´s awareness about electro apparatus hazardousness and electric waste by mean of questionnaires. The thesis first descibe the laws concerning this problem either from the view of dangerous substances or from the view of dangerous waste. Furthermore in the thesis the data taken out of two age groups by questionnaires were elaborated. The questionnaires were focused on the knowledge of dangerous substances and dangerous waste. Toxicological characteristics of dangrous metals are also descbibed in this part
Connection between completion of weight loss program and self efficacy in obese people
The thesis deals with connections between completion of reduced course and self-efficacy of obese people. The theoretical part deals with definition of obesity, its prevalence and aspects of its treatment. A chapter of the theoretical part focuses on self-efficacy and its connections to obesity and physical activity. The last part is about general self-efficacy. The empirical part describes physical activity of obese respondents, changes in their physical activity self-efficacy and their general self-efficacy after completion of reduced course. The questionnaires about the level of physical activity and physical activity self-efficacy were created by author of the thesis. General self-efficacy was measured by General self-efficacy scale. Data were obtained in the first and last lesson of reduced courses. A paired-samples t-test was conducted to compare changes in both areas of self-efficacy. It has been found that frequency of respondents physical activity was insufficient. The results suggest that connection between completion of reduced course and general self-efficacy exist. On the other hand there was not significant difference between individual's physical self-efficacy before reduced course and after its completion. Keywords: obesity, self-efficacy, physical activity self-efficacy, general..
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