POSICIONAMIENTO WEB EN ATRACTIVOS TURÍSTICOS DEL CANTÓN SUCRE, ECUADOR

La presente investigación realizó un análisis de posicionamiento web a partir del entorno de los canales publicitarios digitales, además la evaluación de la presencia online de los atractivos que posee el cantón Sucre, para determinar la calidad o grado de optimización de los medios publicitarios empleados para su promoción y la implementación de acciones que permitan la difusión de la oferta turística a través de motores de búsqueda mediante la utilización de estrategias Optimización para Motores de Búsqueda (SEO) y Marketing en Buscadores (SEM) que mejoren la visibilidad de sitios web orientados a la promoción turística; la mejora de visibilidad en medios sociales populares como Facebook, YouTube, Twitter e Instagram mediante la utilización de técnicas de Marketing en Medios Sociales (SMM) y Optimización en Medios Sociales (SMO). El uso de marketing móvil a través de aplicaciones destinadas a brindar información turística de los atractivos, la captación de emails para el desarrollo de marketing por correo electrónico y la ejecución de campañas de publicidad pagada en internet, destacando además las grandes ventajas competitivas y oportunidades de crecimiento sostenido que brinda la utilización de los medios digitales en relación con los medios publicitarios tradicionales en costos, alcance, usabilidad y medición de resultados.PALABRAS CLAVE: Posicionamiento web; atractivos; medios publicitarios; marketing digital; motores de búsquedas.WEB POSITIONING IN CANTON SUCRE TOURIST ATTRACTIONS, ECUADORABSTRACTThe present research carried out a web positioning analysis based on the environment of the digital advertising channels, besides the evaluation of the online presence of the attractions that has the canton Sucre, to determine the quality or degree of optimization of the publicity means employed for its Promotion and implementation of actions that allow the dissemination of tourism through search engines through the use of search engine optimization (SEO) and Search Engine Marketing (SEM) strategies that improve the visibility of web sites oriented to the Tourist promotion; Improving visibility on popular social media such as Facebook, YouTube, Twitter and Instagram through the use of Social Media Marketing (SMM) and Social Media Optimization (SMO) techniques. The use of mobile marketing through applications designed to provide tourist information about attractiveness, the capture of emails for the development of email marketing and the execution of paid advertising campaigns on the Internet, also highlighting the great competitive advantages and opportunities of Sustained growth in the use of digital media in relation to traditional advertising media in terms of costs, scope, usability and results measurement.KEYWORDS: Web positioning; Attractive; Advertising media; digital marketing; Search engines

Headache, Delirium or Encephalitis?:A Case of Residual Mutism Secondary to Anti-NMDA Receptor Encephalitis

Encephalitis is a heterogeneous syndrome that is diagnosed through clinical assessment and the assistance of laboratory, neuroimaging and electroencephalographic workup. Over the past 10 years, autoimmune encephalitis has been more frequently recognized; however, most reports come from highly specialized hospital settings. Anti-N-methyl-D-aspartate receptor (NDMAR) encephalitis has been associated with paraneoplastic encephalitis syndromes and was first recognized in 2005. We present the case of a 34-year-old male patient who debuted clinically with a headache associated with neuropsychiatric symptoms (i.e., visual and auditory hallucinations, anxiety, aggressiveness) and memory deficits, progressing to autonomic dysfunction (i.e., tachycardia and hypertension), seizures, and stupor with catatonic features. Initially, infectious, metabolic, and toxicological etiologies were excluded; followed by the assessment of immunological and paraneoplastic etiologies, yielding positive IgG levels for anti-NMDAR antibodies. The patient was treated successfully with systemic steroid therapy and therapeutic plasmapheresis, while mutism was the only sequela. Although large case series reporting on paraneoplastic and autoimmune anti-NMDAR encephalitis have been reported in the literature in recent years, this case is of particular importance due to the stepwise differential diagnosis and treatment management procedure that was used in a regional but not highly specialized hospital setting

Patterns of healthy lifestyle behaviours in older adults: findings from the Chilean National Health Survey 2009–2010

The purpose of this study was to investigate healthy lifestyle behaviours across age categories in the older population in Chile. Data from 1390 older adults (≥60 years), in the 2009–2010 Chilean National Health Survey were analyzed. We derived the following age categories: 60–65, 66–70, 71–75, 76–80 and >80 years. The association between age and compliance with healthy lifestyle behaviours (smoking, sitting time, physical activity, sleep duration and intake of salt, alcohol, fruit and vegetables) were investigated using logistic regression. The probability of meeting the guidelines for alcohol intake (OR trend: 1.35 [95% CI: 1.11; 1.64], p = 0.001) and smoking (OR trend: 1.23 [95% CI: 1.13; 1.33], p < 0.0001) increased with age, whereas spending <4 h per day sitting time or engaging in at least 150 min of physical activity per week or sleep on average between 7 and 9 h per day were less likely to be met with increasing age (OR trend: 0.77 [95% CI: 0.71; 0.83], p < 0.000; OR trend: 0.73 [95% CI: 0.67; 0.79], p < 0.0001, and OR trend: 0.89 [95% CI: 0.82; 0.96], p = 0.002, respectively). No significant trend across age categories was observed for fruit and vegetables, and salt intake. The probability of meeting at least 3 out of 7 healthy lifestyle behaviours across the age categories was also lower in older age categories compared to those aged 60 to 65 years. Overall, in older adults the probability of having the healthy lifestyle behaviours of physical activity, sitting time and sleeping behaviours was low but not for smoking or alcohol consumption. With an increasingly ageing population, these findings could inform stakeholders on which lifestyle behaviours could be targeted in the older adults and therefore which interventions should take place to promote healthy ageing

Association of leisure time and occupational physical activity with obesity and cardiovascular risk factors in Chile

The aim of this study was to investigate the association between physical activity (PA), both occupational (OPA) and during leisure time (LTPA), with obesity and cardiovascular risk factors in Chilean adults. 5,157 participants from the Chilean National Health Survey 2009–2010 were included in this study. OPA and LTPA levels were assessed using the Global Physical Activity Questionnaire. The association between both PA with obesity and cardiovascular risk factors was determined using logistic regression. Our findings showed a significant trend between higher LTPA and lower odds for obesity (OR 0.64 [95% CI: 0.53; 0.76], central obesity 0.52 [0.44; 0.61]) and other cardiovascular risk factors including diabetes (OR: 0.72 [0.55; 0.94]), hypertension (OR: 0.59 [0.50; 0.71]) and metabolic syndrome (OR: 0.62 [0.50; 0.78]). In contrast, OPA was only associated with lower odds of diabetes (OR: 0.79 [0.65; 0.98]) and hypertension (0.85 [0.74; 0.98]). In conclusion, LTPA was associated with a lower risk of all major cardiovascular risk factors, whereas OPA was only associated with a lower risk of diabetes and hypertension

Traqueomalacia en la unidad de cuidados críticos. Reporte de 2 casos

Introduction: Tracheomalacia in critical care is a rare entity in the adult population, so we present two relevant clinical cases, where a striking deformity of the trachea was evident. In the first case, concomitantly with other diseases such as thyroid pathologies (goiter) and in the second case as a result of severe burns, product of the explosion of a gas canister for domestic use. Objective: to describe two clinical cases of patients with tracheomalacia in critical care unit and to recognize the main diagnostic and therapeutic methods. Materials and methods: a retrospective descriptive study was performed, presentation of 2 clinical cases, with a diagnosis of tracheomalacia in the critical care unit; institutional informed consent was requested for review of clinical histories of the patients studied and publication of the respective images. Discussion: The main signs and symptoms in both clinical cases were dyspnea, hypoxemia and failure of extubation. In the first clinical case, the diagnosis of tracheomalacia, was found during surgery for exeresis of thyroid tumor, in the second case the diagnosis was made by fibrobronchoscopy and anatomical loss was observed in the normal way, cylindrical of the trachea. With regard to treatment, it should be emphasized that tracheal surgery and the development of endoluminal tracheal prostheses currently represent a great therapeutic alternative. Conclusions: tracheomalacia can cause serious changes in oxygenation so it is important to recognize, diagnose and treat this pathology in a timely manner, as it represents a high comorbidity in the critical patient, which increases the need for reintubation and increases failure in disconnecting mechanical ventilation.Introducción: Traqueomalacia en cuidados críticos, es una entidad poco frecuente en la población adulta, por lo que, presentamos dos casos clínicos relevantes, donde se evidenció una llamativa deformidad de la tráquea.  En el primer caso, concomitantemente con otras enfermedades tales como, patologías tiroideas (bocio) y en el segundo caso a consecuencia de quemaduras severas, producto de la explosión de una bombona de gas de uso doméstico. Objetivo: describir dos casos clínicos de pacientes con traqueomalacia en unidad de cuidados críticos y reconocer los principales métodos diagnósticos y terapéuticos. Materiales y métodos: se realizó un estudio descriptivo, retrospectivo, presentación de 2 casos clínicos, con diagnóstico de traqueomalacia en la unidad de cuidados críticos; se solicitó el consentimiento informado institucional para revisión de historias clínicas de los pacientes estudiados y publicación de las imágenes respectivas.  Discusión:  Los principales signos y síntomas en ambos casos clínicos fueron:  disnea, hipoxemia y fracaso de la extubación. En el primer caso clínico, el diagnóstico de traqueomalacia, resultó como hallazgo durante una intervención quirúrgica por exeresis de tumor de tiroides, en el segundo caso el diagnóstico se realizó mediante   fibrobroncoscopía y se observó una pérdida anatómica de la forma normal, cilíndrica de la tráquea. Respecto al tratamiento cabe recalcar que en la actualidad la cirugía de tráquea y el desarrollo de prótesis traqueales endoluminales representan una gran alternativa terapéutica. Conclusiones:  la traqueomalacia puede provocar cambios graves en la oxigenación por lo que es importante reconocer, diagnosticar y tratar oportunamente esta patología, por representar una gran comorbilidad en el paciente crítico, que incrementa la necesidad de reintubación y aumenta el fracaso en la desconexión de la ventilación mecánica

Five new species of Ectobiidae (Blattodea) collected in the Reserva Ducke, Amazonas, Brazil

Herein we describe five new species of the Ectobiidae subfamilies Pseudophyllodromiinae (Amazonina spiculata sp. nov., Amazonina spinostylata sp. nov., Cariblatta duckeniana sp. nov., Cariblatta manauensis sp. nov.) and Nyctiborinae (Nyctibora nigra sp. nov.), collected in the Reserva Ducke, Manaus, state of Amazonas. The specimens were collected from litter, fallen logs, branches, and foliage. We illustrate the male genitalia of the new species

CIBERER : Spanish national network for research on rare diseases: A highly productive collaborative initiative

Altres ajuts: Instituto de Salud Carlos III (ISCIII); Ministerio de Ciencia e Innovación.CIBER (Center for Biomedical Network Research; Centro de Investigación Biomédica En Red) is a public national consortium created in 2006 under the umbrella of the Spanish National Institute of Health Carlos III (ISCIII). This innovative research structure comprises 11 different specific areas dedicated to the main public health priorities in the National Health System. CIBERER, the thematic area of CIBER focused on rare diseases (RDs) currently consists of 75 research groups belonging to universities, research centers, and hospitals of the entire country. CIBERER's mission is to be a center prioritizing and favoring collaboration and cooperation between biomedical and clinical research groups, with special emphasis on the aspects of genetic, molecular, biochemical, and cellular research of RDs. This research is the basis for providing new tools for the diagnosis and therapy of low-prevalence diseases, in line with the International Rare Diseases Research Consortium (IRDiRC) objectives, thus favoring translational research between the scientific environment of the laboratory and the clinical setting of health centers. In this article, we intend to review CIBERER's 15-year journey and summarize the main results obtained in terms of internationalization, scientific production, contributions toward the discovery of new therapies and novel genes associated to diseases, cooperation with patients' associations and many other topics related to RD research

The IceCube Neutrino Observatory, the Pierre Auger Observatory and the Telescope Array: Joint Contribution to the 34th International Cosmic Ray Conference (ICRC 2015)

We have conducted three searches for correlations between ultra-high energy cosmic rays detected by the Telescope Array and the Pierre Auger Observatory, and high-energy neutrino candidate events from IceCube. Two cross-correlation analyses with UHECRs are done: one with 39 cascades from the IceCube `high-energy starting events' sample and the other with 16 high-energy `track events'. The angular separation between the arrival directions of neutrinos and UHECRs is scanned over. The same events are also used in a separate search using a maximum likelihood approach, after the neutrino arrival directions are stacked. To estimate the significance we assume UHECR magnetic deflections to be inversely proportional to their energy, with values $3^\circ$, $6^\circ$ and $9^\circ$ at 100 EeV to allow for the uncertainties on the magnetic field strength and UHECR charge. A similar analysis is performed on stacked UHECR arrival directions and the IceCube sample of through-going muon track events which were optimized for neutrino point-source searches.Comment: one proceeding, the 34th International Cosmic Ray Conference, 30 July - 6 August 2015, The Hague, The Netherlands; will appear in PoS(ICRC2015