Su dağıtım şebekelerinin karışık-tamsayılı lineer programlama kullanılarak optimizasyonu.

The present study aims to discuss the advantages and disadvantages of the design of water distribution networks by making use of mixed integer linear programming. The developed optimization algorithm considers the minimization of the total cost as the objective function. The total cost of water distribution network is defined as cost of pipes, reservoirs and pumps. Nodal demands, nodal pressure limits and pipe velocity limits are satisfied while optimizing the network. Energy equation is the equality constraint that is satisfied for all the links of the network. In this study, the method proposed by Samani and Zanganeh (2010) is coded as Java based computer program. The consistency of the proposed method is tested on three networks and further improvement is achieved by making changes on proposed method. The developed computer program finds the optimal values of the decision variables which are the pipe diameters, reservoir heights and pump characteristics. The solution of the optimization problem is iteratively obtained by running both hydraulic solver (EPANET) and linear programming solver (lp_solve) in succession. Results are compared with previous studies.M.S. - Master of Scienc

A Neural Network Based Decision Support System for Real-Time Scheduling of Flexible Manufacturing Systems

The objective of this study is to develop a neural network based decision support system for selection of appropriate dispatching rules for a real-time manufacturing system, in order to obtain the desired performance measures given by a user, at different scheduling periods. A simulation experiment is integrated with a neural network to obtain the multi-objective scheduler, where simulation is used to provide the training data. The proposed methodology is illustrated on a flexible manufacturing system (FMS) which consists of several number of machines and jobs, loading/unloading stations and automated guided vehicles (AGVs) to transport jobs from one location to another

Potentiometric monitoring of cobalt in beer sample by solid contact ion selective electrode

A new solid contact cobalt selective electrode was constructed with 4-tert-butylthiacalix[4]arene as ionophore. The best performance was observed with the membrane having an ionophore/polyvinyl chloride/sodium tetraphenylborate/nitrophenyl octyl ether ratio of 3.5:33:1.5:62 (w/w; mg). The electrode, under steady-state conditions, exhibited a working concentration range of 1 × 10−1 – 1 × 10−6 mol/L with a near-Nernstian slope of 25.3 mV/decade and a detection limit of 3.5 × 10−7 mol/L. The electrode had a very short response time (<10 seconds) and good reproducibility at a working pH range of 4.0–6.5. The electrode was used for 4 months without any significant change in its sensitivity. The potentiometric performance of the electrode in partially nonaqueous medium [up to 20 % (v/v) alcohol] was found satisfactory. The performance of the prepared electrode for the analysis of beer samples using direct potentiometric method is very encouraging

Farklı lokalizasyonlarda marjinal zon lenfoma

[EP067][Baş ve Boyun Cerrahisi]FARKLI LOKALİZASYONLARDA MARJİNAL ZON LENFOMASedat Aydın1, Mehmet Gökhan Demir2, Ayşegül Uzun1, Eren Boldaz1, Abdussamet Faraşoğlu11Sağlık Bilimleri Üniversitesi Kartal Dr Lütfi Kırdar EAH KBB Kliniği İstanbul2Etimesgut Devlet Hastanesi KBB kliniği AnkaraAmaç: Non Hodgkin lenfoma (NHL) baş boyun bölgesi malinitelerinin % 25’ini oluşturmaktadır. Bu tümörlerin çoğu farenks, paranazal sinüs, nazal kavite, oral kavitede vs. yer almaktadır. Bu lokalizasyonlar arasında parotis bezi nadir bir lokalizasyondur. Parotis bezi malinitelerinin sadece %1.7-3.1’ini lenfomalar oluşturmaktadır. Tonsil marjinal zon lenfomasıda nadir bir lenfoma türüdür. bu çalışmadaki amacımız farklı lokalizasyonlarda karşılaşabileceğimiz MALTOMA olgularına dikkat çekmektir. Olgunun özellikleri: Olgu 1: Yutmada güçlük ve yutma esnasında takılma hissi olan hastada tonsilde kitle tespit edilmiş olup yapılan tonsillektomi sonrasında tonisilde MALTOMA tanısı kondu. Olgu 2: Parotis lokalizasyonunda kitle nedeni ile kliniğe başvuran tekrarlanan İİAB’ye rağmen tanı konulamayan ve bu güçlük sonrasında tanı amacı ile parotidektomi yapılan hastada MALTOMA tanısı kondu.TedaviHer ikikemoterapiher hangiYorum: İki farklı lokalizasyonda yer alan MALTOMA tanısı konmuş vakaları sunduk. Bir olguda tanıca güçlük yaşamamıza rağmen diğer vakada kolaylıkla tanı koyabildik. Kulak burun boğaz pratiğinde kitlesel lezyon ile karşılaştığımızda MALTOMA tanısı aklımızda bulundurmamız da fayda vardır.Anahtar Kelimeler:Marjinal zon lenfoma, Non hodgkin lenfoma, Parotis, Tonsi

A novel prognostic risk factor for patients undergoing radical prostatectomy: Triglyseride-glucose index

Background: Obesity and metabolic syndrome are growing health problems in western countries. Recently reported triglyseride-glucose (TyG) index is a reliable and accessible indicator of metabolic syndrome. TyG index could be used as a indicator of a prognostic risk factor for metabolic syndrome-related cancers. Objectives: To investigate the prognostic role of TyG index on oncological outcomes in patients undergoing radical prostatectomy. Design, Setting and Participants: Data from 200 men who underwent radical prostatectomy were used. Outcome Measurements and Statsitical Analyse: TyG was calculated based on TyG index = Ln [TG (mg/dL) FPG (mg/dL)/2] formula. Patients were divided into two groups according to the 8.55 level as cut-off value for TyG index. Laboratory results, oncological outcomes and survivals were comparised statistically between groups. Results: Mean ages of patients were 64.32 +/- 6.1 years and median follow-up time was 61.6 +/- 35 (range 4-140) month. Biochemical recurrens was observed in 42 (21%) patients. Positive correlation between TyG index, body mass index, waist circumference, prostate biopsy gleason score, clinical T stage, positive surgical margin, pathological T stage and biochemical recurrence were observed. There was no statistical significance in terms of survival between groups. Conclusion: Association between TyG index and prostate cancer may facilitate to predict unfavorable prognostic factors of radical prostatectomy. Increased TyG index may use as a predictive marker of positive surgical margin status before radical prostatectomy, BCR, advanced cT and pT stages after radical prostatectomy or worse biopsy gleason score in clinical practice