Intra-osseous synovial sarcoma.

Intra-osseous synovial sarcoma is very rare and its mode of origin is conjectural. Our patient's tumour was situated within the lower femur. The sited of origin of the few intra-osseous synovial sarcomas so far documented may support the concept of intra-osseous synovial rests

Academic staffing patterns in nursing colleges in Natal and Transvaal

The purpose of this study was to determine post structure in Natal and Transvaal nursing colleges, the extent to which these posts are filled by suitably qualified tutors and the workload of the academic staff in relation to post level and qualifications. Two hundred and thirty-three nurse tutors participated in the study. Data were collected by a questionnaire developed by the researcher. Findings revealed that the post structure was similar in Natal and Transvaal nursing colleges and the workload of nurse tutors was recorded

Results from South Africa's 2016 report card on physical activity for children and youth

Background: We present results of the 2016 Healthy Active Kids South Africa (HAKSA) Report Card on the current status of physical activity (PA) and nutrition in South African youth. The context in which we interpret the findings is that participation in PA is a fundamental human right, along with the right to "attainment of the highest standard of health." Methods: The HAKSA 2016 Writing Group was comprised of 33 authorities in physical education, exercise science, nutrition, public health, and journalism. The search strategy was based on peer-reviewed manuscripts, dissertations, and 'gray' literature. The core PA indicators are Overall Physical Activity Level; Organized Sport Participation; Active and Outdoor Play; Active Transportation; Sedentary Behaviors; Family and Peer Influences; School; Community and the Built Environment; and National Government Policy, Strategies, and Investment. In addition, we reported on Physical Fitness and Motor Proficiency separately. We also reported on nutrition indicators including Overweight and Under-nutrition along with certain key behaviors such as Fruit and Vegetable Intake, and policies and programs including School Nutrition Programs and Tuck Shops. Data were extracted and grades assigned after consensus was reached. Grades were assigned to each indicator ranging from an A, succeeding with a large majority of children and youth (81% to 100%); B, succeeding with well over half of children and youth (61% to 80%); C, succeeding with about half of children and youth (41% to 60%); D, succeeding with less than half but some children and youth (21% to 40%); and F, succeeding with very few children and youth (0% to 20%); INC is inconclusive. Results: Overall PA levels received a C grade, as we are succeeding with more than 50% of children meeting recommendations. Organized Sports Participation also received a C, and Government Policies remain promising, receiving a B. Screen time and sedentary behavior were a major concern. Under-and over-weight were highlighted and, as overweight is on the rise, received a D grade. Conclusion: In particular, issues of food security, obesogenic environments, and access to activity-supportive environments should guide social mobilization downstream and policy upstream. There is an urgent need for practice-based evidence based on evaluation of existing, scaled up interventions.Scopu

Trapped-ion probing of light-induced charging effects on dielectrics

We use a string of confined $^{40}$Ca$^+$ ions to measure perturbations to a trapping potential which are caused by light-induced charging of an anti-reflection coated window and of insulating patches on the ion-trap electrodes. The electric fields induced at the ions' position are characterised as a function of distance to the dielectric, and as a function of the incident optical power and wavelength. The measurement of the ion-string position is sensitive to as few as $40$ elementary charges per $\sqrt{\mathrm{Hz}}$ on the dielectric at distances of order millimetres, and perturbations are observed for illumination with light of wavelengths as long as 729\,nm. This has important implications for the future of miniaturised ion-trap experiments, notably with regards to the choice of electrode material, and the optics that must be integrated in the vicinity of the ion. The method presented can be readily applied to the investigation of charging effects beyond the context of ion trap experiments.Comment: 11 pages, 5 figure

Cavity cooling of a nanomechanical resonator by light scattering

We present a novel method for opto-mechanical cooling of sub-wavelength sized nanomechanical resonators. Our scheme uses a high finesse Fabry-Perot cavity of small mode volume, within which the nanoresonator is acting as a position-dependant perturbation by scattering. In return, the back-action induced by the cavity affects the nanoresonator dynamics and can cool its fluctuations. We investigate such cavity cooling by scattering for a nanorod structure and predict that ground-state cooling is within reach.Comment: 4 pages, 3 figure

The ride comfort vs. handling compromise for off-road vehicles

When designing vehicle suspension systems, it is well-known that spring and damper characteristics required for good handling on a vehicle are not the same as those required for good ride comfort. Any choice of spring and damper characteristic is therefore necessarily a compromise between ride comfort and handling. The compromise is more pronounced on off-road vehicles, as they require good ride comfort over rough off-road terrain, as well as acceptable on-road handling. In this paper, the ride comfort vs. handling compromise for off-road vehicles is investigated by means of three case studies. All three case studies indicate that the spring and damper charcteristics required for ride comfort and handling lie on opposite extremes of the design space. Design criteria for a semi-active suspension system, that could significantly reduce, or even eliminate the ride comfort vs. handling compromise, are proposed. The system should be capable of switching safely and predictably between a stiff spring and high damping mode (for handling) as well as a soft spring and low damping mode (for ride comfort). A possible solution to the compromise, in the form of a four state, semi-active hydropneumatic spring-damper system, is proposed.US Government through its European Research Office of the US Army under Contracts N68171-01-M-5852, N62558-02-M-6372 and N62558-04-P-6004.http://www.elsevier.com/locate/jterrahb201

Dynamics of quantum quenching for BCS-BEC systems in the shallow BEC regime

The problem of coupled Fermi-Bose mixtures of an ultracold gas near a narrow Feshbach resonance is approached through the time-dependent and complex Ginzburg-Landau (TDGL) theory. The dynamical system is constructed using Ginzburg-Landau-Abrikosov-Gor'kov (GLAG) path integral methods with the single mode approximation for the composite Bosons, and the equilibrium states are obtained in the BEC regime for adiabatic variations of the Feshbach detuning along the stationary solutions of the dynamical system. Investigations into the rich superfluid dynamics of this system in the shallow BEC regime yields the onset of multiple interference patterns in the dynamics as the system is quenched from the deep-BEC regime. This results in a partial collapse and revival of the coherent matter wave field of the BEC, whose temporal profile is reported.Comment: 24 pages, 7 figures. Submitted to European Journal of Physics Plu

The Effects of Cocaine on Different Redox Forms of Cysteine and Homocysteine, and on Labile, Reduced Sulfur in the Rat Plasma Following Active versus Passive Drug Injections

Received: 28 November 2012 / Revised: 19 April 2013 / Accepted: 6 May 2013 / Published online: 16 May 2013 The Author(s) 2013. This article is published with open access at Springerlink.comThe aim of the present studies was to evaluate cocaine-induced changes in the concentrations of different redox forms of cysteine (Cys) and homocysteine (Hcy), and products of anaerobic Cys metabolism, i.e., labile, reduced sulfur (LS) in the rat plasma. The above-mentioned parameters were determined after i.p. acute and subchronic cocaine treatment as well as following i.v. cocaine self-administration using the yoked procedure. Additionally, Cys, Hcy, and LS levels were measured during the 10-day extinction training in rats that underwent i.v. cocaine administration. Acute i.p. cocaine treatment increased the total and protein-bound Hcy contents, decreased LS, and did not change the concentrations of Cys fractions in the rat plasma. In turn, subchronic i.p. cocaine administration significantly increased free Hcy and lowered the total and protein-bound Cys concentrations while LS level was unchanged. Cocaine self-administration enhanced the total and protein-bound Hcy levels, decreased LS content, and did not affect the Cys fractions. On the other hand, yoked cocaine infusions did not alter the concentration of Hcy fractions while decreased the total and protein-bound Cys and LS content. This extinction training resulted in the lack of changes in the examined parameters in rats with a history of cocaine self-administration while in the yoked cocaine group an increase in the plasma free Cys fraction and LS was seen. Our results demonstrate for the first time that cocaine does evoke significant changes in homeostasis of thiol amino acids Cys and Hcy, and in some products of anaerobic Cys metabolism, which are dependent on the way of cocaine administration

Management of febrile neutropenia in the United Kingdom: time for a national trial?

Recent advances in febrile neutropenia (FN) have highlighted the value of risk stratification and the evolving role of oral antibiotics with early hospital discharge in low-risk patients. The aim of this study was to survey whether these advances have been translated into routine clinical practice in the UK. Questionnaires were sent to cancer clinicians across the UK to determine clinicians' routine management of FN, including use of risk stratification, antibiotic regimen and criteria for hospital discharge. In all, 128 clinicians responded, representing 50 cancer departments (83%). Only 38% of respondents stratify patients according to risk and with substantial variation in the criteria defining ‘low-risk'. Furthermore, only 22% of clinicians use oral antibiotics as first-line treatment in any patients with FN, but this was significantly greater among clinicians who do compared to those who do not stratify patients by risk, 51 vs 4% (P<0.0001). These findings suggest a slow and/or cautious introduction of newer strategies for the management of low-risk FN in the UK. However, 84% of respondents confirmed their willingness to participate in a trial of oral antibiotics combined with early discharge in low-risk FN