18 research outputs found
Detections of [C II] 158 m and [O III] 88 m in a Local Lyman Continuum Emitter, Mrk 54, and its Implications to High-redshift ALMA Studies
We present integral field, far-infrared (FIR) spectroscopy of Mrk 54, a local
Lyman Continuum Emitter (LCE), obtained with FIFI-LS on the Stratospheric
Observatory for Infrared Astronomy. This is only the second time, after Haro
11, that [C II] 158 m and [O III] 88 m spectroscopy of the known LCEs
have been obtained. We find that Mrk 54 has a strong [C II] emission that
accounts for % of the total FIR luminosity, whereas it has only moderate
[O III] emission, resulting in the low [O III]/[C II] luminosity ratio of
. In order to investigate whether [O III]/[C II] is a useful
tracer of (LyC escape fraction), we examine the correlations of
[O III]/[C II] and (i) the optical line ratio of [O III]
5007 \AA/[O II] 3727 \AA, (ii) specific star formation rate, (iii) [O III] 88
m/[O I] 63 m ratio, (iv) gas phase metallicity, and (v) dust
temperature based on a combined sample of Mrk 54 and the literature data from
the Herschel Dwarf Galaxy Survey and the LITTLE THINGS Survey. We find that
galaxies with high [O III]/[C II] luminosity ratios could be the result of high
ionization (traced by ), bursty star formation, high
ionized-to-neutral gas volume filling factors (traced by [O III] 88 m/[O
I] 63 m), and low gas-phase metallicities, which is in agreement with
theoretical predictions. We present an empirical relation between the [O
III]/[C II] ratio and based on the combination of the [O III]/[C
II] and correlation, and the known relation between
and . The relation implies that high-redshift galaxies with high
[O III]/[C II] ratios revealed by ALMA may have ,
significantly contributing to the cosmic reionization.Comment: 14 pages, 5 figures, Accepted for publication in Ap
Influx of nitrogen-rich material from the outer Solar System indicated by iron nitride in Ryugu samples
Large amounts of nitrogen compounds, such as ammonium salts, may be stored in icy bodies and comets, but the transport of these nitrogen-bearing solids into the near-Earth region is not well understood. Here, we report the discovery of iron nitride on magnetite grains from the surface of the near-Earth C-type carbonaceous asteroid Ryugu, suggesting inorganic nitrogen fixation. Micrometeoroid impacts and solar wind irradiation may have caused the selective loss of volatile species from major iron-bearing minerals to form the metallic iron. Iron nitride is a product of nitridation of the iron metal by impacts of micrometeoroids that have higher nitrogen contents than the CI chondrites. The impactors are probably primitive materials with origins in the nitrogen-rich reservoirs in the outer Solar System. Our observation implies that the amount of nitrogen available for planetary formation and prebiotic reactions in the inner Solar System is greater than previously recognized
Four‐dimensional‐STEM analysis of the phyllosilicate‐rich matrix of Ryugu samples
Ryugu asteroid grains brought back to the Earth by the Hayabusa2 space mission are pristine samples containing hydrated minerals and organic compounds. Here, we investigate the mineralogy of their phyllosilicate-rich matrix with four-dimensional scanning transmission electron microscopy (4D-STEM). We have identified and mapped the mineral phases at the nanometer scale (serpentine, smectite, pyrrhotite), observed the presence of Ni-bearing pyrrhotite, and identified the serpentine polymorph as lizardite, in agreement with the reported aqueous alteration history of Ryugu. Furthermore, we have mapped the d-spacings of smectite and observed a broad distribution of values, ranging from 1 to 2 nm, with an average d-spacing of 1.24 nm, indicating significant heterogeneity within the sample. Such d-spacing variability could be the result of either the presence of organic matter trapped in the interlayers or the influence of various geochemical conditions at the submicrometer scale, suggestive of a range of organic compounds and/or changes in smectite crystal chemistry
A dehydrated space-weathered skin cloaking the hydrated interior of Ryugu
Without a protective atmosphere, space-exposed surfaces of airless Solar System bodies gradually experience an alteration in composition, structure and optical properties through a collective process called space weathering. The return of samples from near-Earth asteroid (162173) Ryugu by Hayabusa2 provides the first opportunity for laboratory study of space-weathering signatures on the most abundant type of inner solar system body: a C-type asteroid, composed of materials largely unchanged since the formation of the Solar System. Weathered Ryugu grains show areas of surface amorphization and partial melting of phyllosilicates, in which reduction from Fe3+ to Fe2+ and dehydration developed. Space weathering probably contributed to dehydration by dehydroxylation of Ryugu surface phyllosilicates that had already lost interlayer water molecules and to weakening of the 2.7 µm hydroxyl (–OH) band in reflectance spectra. For C-type asteroids in general, this indicates that a weak 2.7 µm band can signify space-weathering-induced surface dehydration, rather than bulk volatile loss
Omecamtiv mecarbil in chronic heart failure with reduced ejection fraction, GALACTIC‐HF: baseline characteristics and comparison with contemporary clinical trials
Aims:
The safety and efficacy of the novel selective cardiac myosin activator, omecamtiv mecarbil, in patients with heart failure with reduced ejection fraction (HFrEF) is tested in the Global Approach to Lowering Adverse Cardiac outcomes Through Improving Contractility in Heart Failure (GALACTIC‐HF) trial. Here we describe the baseline characteristics of participants in GALACTIC‐HF and how these compare with other contemporary trials.
Methods and Results:
Adults with established HFrEF, New York Heart Association functional class (NYHA) ≥ II, EF ≤35%, elevated natriuretic peptides and either current hospitalization for HF or history of hospitalization/ emergency department visit for HF within a year were randomized to either placebo or omecamtiv mecarbil (pharmacokinetic‐guided dosing: 25, 37.5 or 50 mg bid). 8256 patients [male (79%), non‐white (22%), mean age 65 years] were enrolled with a mean EF 27%, ischemic etiology in 54%, NYHA II 53% and III/IV 47%, and median NT‐proBNP 1971 pg/mL. HF therapies at baseline were among the most effectively employed in contemporary HF trials. GALACTIC‐HF randomized patients representative of recent HF registries and trials with substantial numbers of patients also having characteristics understudied in previous trials including more from North America (n = 1386), enrolled as inpatients (n = 2084), systolic blood pressure < 100 mmHg (n = 1127), estimated glomerular filtration rate < 30 mL/min/1.73 m2 (n = 528), and treated with sacubitril‐valsartan at baseline (n = 1594).
Conclusions:
GALACTIC‐HF enrolled a well‐treated, high‐risk population from both inpatient and outpatient settings, which will provide a definitive evaluation of the efficacy and safety of this novel therapy, as well as informing its potential future implementation
Extracellular Vesicle-Mediated Secretion of Protochlorophyllide in the Cyanobacterium <i>Leptolyngbya boryana</i>
Protochlorophyllide (Pchlide) reduction in the late stage of chlorophyll a (Chl) biosynthesis is catalyzed by two enzymes: light-dependent Pchlide oxidoreductase (LPOR) and dark-operative Pchlide oxidoreductase (DPOR). The differential operation of LPOR and DPOR enables a stable supply of Chl in response to changes in light conditions and environmental oxygen levels. When a DPOR-deficient mutant (YFC2) of the cyanobacterium Leptolyngbya boryana is grown heterotrophically in the dark, Pchlide accumulates in the cells and is secreted into the culture medium. In this study, we demonstrated the extracellular vesicle-mediated secretion of Pchlide. Pchlide fractions were isolated from the culture medium using sucrose density gradient centrifugation. Mass spectrometry analysis revealed that the Pchlide fractions contained porin isoforms, TolC, and FG-GAP repeat-containing protein, which are localized in the outer membrane. Transmission electron microscopy revealed extracellular vesicle-like structures in the vicinity of YFC2 cells and the Pchlide fractions. These findings suggested that the Pchlide secretion is mediated by extracellular vesicles in dark-grown YFC2 cells
RIOJA I. The core of the highest redshift galaxy overdensity at confirmed by NIRSpec/JWST
The proto-clusters in the epoch of reionization, traced by galaxies
overdensity regions, are ideal laboratories to study the process of stellar
assembly and cosmic reionization. We present the spectroscopic confirmation of
the core of the most distant proto-cluster at , A2744-z7p9OD, with
the James Webb Space Telescope NIRSpec integral field unit spectroscopy. The
core region includes as many as 4 galaxies detected in [O III] 4960 A and 5008
A in a small area of , corresponding to 11 kpc
11 kpc. Three member galaxies are also tentatively detected in dust
continuum in ALMA Band 6, which is consistent with their red ultraviolet
continuum slopes, . The member galaxies have stellar masses in
the range of log() and star formation rates
of yr, showing a diversity in their
properties. FirstLight cosmological simulations reproduce the physical
properties of the member galaxies including the stellar mass, [OIII]
luminosity, and dust-to-stellar mass ratio, and predict that the member
galaxies are on the verge of merging in a few to several tens Myr to become a
large galaxy with . The presence of
a multiple merger and evolved galaxies in the core region of A2744-z7p9OD
indicates that environmental effects are already at work 650 Myr after the Big
Bang.Comment: 10 pages, 4 figures, 1 table, submitted to ApJ