Die Bundesverkehrswegeplanung schleunigst modernisieren

DIE BUNDESVERKEHRSWEGEPLANUNG SCHLEUNIGST MODERNISIEREN Die Bundesverkehrswegeplanung schleunigst modernisieren / Maier, Urs (Rights reserved) ( -

Subsea Compression Applications ,

TutorialTutorial 22: The use of Subsea gas compression technology for subsea re-injection and/or gas transport boosting represents a new and exciting application for rotating equipment, which will allow new gas/condensate field production opportunities, enhanced recovery of existing gas/condensate fields and cost effective production from marginal gas fields. This panel session includes short presentations on the benefits of subsea compression, an overview of currently ongoing projects, and recent advances and technologies that are available and/or under development for subsea gas compression. The panel session includes presentations from SIEMENS ENERGY, MAN DIESEL & TURBO, GE OIL & GAS, and DRESSER-RAND and. The respective presentation titles are: 1. Subsea Electrical Distribution – Siemens Energy, 2. HOFIMTM Type Compressors for Subsea Applications – MAN Diesel & Turbo, 3. GE Oil & Gas Experience in Subsea Gas Compression– GE Oil & Gas, and 4. DATUM I Compressor for Subsea Applications: Update on Qualification Efforts- Dresser-Ran

Subsea Compression Applications - Panel Session

TutorialThe use of Subsea gas compression technology for subsea re-injection and/or gas transport boosting represents a new and exciting application for rotating equipment, which will allow new gas/condensate field production opportunities, enhanced recovery of existing gas/condensate fields and cost effective production from marginal gas fields. This panel session includes short presentations on the benefits of subsea compression, an overview of currently ongoing projects, and recent advances and technologies that are available and/or under development for subsea gas compression. The panel session includes presentations from STATOIL, INTECSEA, MAN DIESEL & TURBO, GE OIL & GAS and DRESSER-RAND. The respective presentation titles are: DATUM I Compressor for Subsea Applications: Update on Qualification Efforts- Dresser-Rand; HOFIMTM Type Compressors for Subsea Applications – MAN Diesel & Turbo; Improving Recovery with Subsea Compression – INTECSEA; GE Oil & Gas Experience in Subsea Gas Compression technology Development – GE Oil & Gas; Realization of Subsea Gas Compression – Statoil

Subsea Compression Applications - Panel Session

TutorialThe use of Subsea gas compression technology for subsea re-injection and/or gas transport boosting represents a new and exciting application for rotating equipment, which will allow new gas/condensate field production opportunities, enhanced recovery of existing gas/condensate fields and cost effective production from marginal gas fields. This panel session includes short presentations on the benefits of subsea compression, an overview of currently ongoing projects, and recent advances and technologies that are available and/or under development for subsea gas compression. The panel session includes presentations from Shell Global Solutions, Aker Solutions, MAN DIESEL & TURBO, GE OIL & GAS and DRESSER-RAND. The respective presentation titles are: Subsea Processing - Multiphase Boosting and Compression – Shell Global Solutions; Subsea Compression; Present Status and Experience – Aker Solutions; HOFIMTM Type Compressors for Subsea Applications; MAN Diesel & Turbo; GE Oil & Gas Experience in Subsea Gas Compression Technology Development – GE Oil & Gas; DATUM I Compressor for Subsea Applications: Update on Qualification Efforts- Dresser-Rand

Trace analysis of environmental matrices by large-volume injection and liquid chromatography-mass spectrometry

The time-honored convention of concentrating aqueous samples by solid-phase extraction (SPE) is being challenged by the increasingly wide spread use of large-volume injection (LVI) liquid chromatography-mass spectrometry (LC-MS) for the determination of traces of polar organic contaminants in environmental samples. Although different LVI approaches have been proposed over the last 40 years, the simplest and most popular way of performing LVI is known as single column LVI (SC-LVI), in which a large-volume of an aqueous sample is directly injected into an analytical column. For the purposes of this critical review, LVI is defined as an injected sample volume that is ≥ 10% of the void volume of the analytical column. Compared to other techniques, SC-LVI is easier to set up, as it only requires small hardware modifications to existing autosamplers and, thus, will represent the main focus of the current review. Although not new, SC-LVI is gaining acceptance and the approach is emerging as a technology that will render SPE nearly obsolete for many environmental applications. In this review, we discuss 1) the history and development of various forms of LVI, 2) the critical factors that one needs to consider when creating and optimizing SC-LVI methods and 3) example applications that demonstrate the range of environmental matrices, to which LVI is applicable such as drinking water, groundwater and surface water including seawater as well as wastewater. Furthermore, we give responses to answer a set of ‘frequently asked questions’ typically encountered from audiences and we indicate future directions and areas that need to be addressed to fully delineate the limits of SC-LVI.Keywords: Direct injection, Soil, Water, LC-MS/MS, Sample preparation, Large-volume injection, Wastewater, Solid-phase extraction, Liquid chromatograph

Agenten organisieren ein Intranet: Ein agentenbasierter Ansatz der Implementierung von Organisation auf Intranets

Zusammenfassung: 'Das Papier präsentiert ein Konzept für die Modellierung von Organisationen als System von kommunizierenden Agenten, eine Referenzarchitektur für agentenbasierte Modellierung von betrieblichen Anwendungen und ein ganzheitliches Konzept für die gemeinsame Entwicklung von Organisationen und Kommunikationskanälen

PTEN controls glandular morphogenesis through a juxtamembrane β-Arrestin1/ARHGAP21 scaffolding complex

PTEN controls three-dimensional (3D) glandular morphogenesis by coupling juxtamembrane signalling to mitotic spindle machinery. While molecular mechanisms remain unclear, PTEN interacts through its C2 membrane-binding domain with the scaffold protein β-Arrestin1. Because β-Arrestin1 binds and suppresses the Cdc42 GTPase-activating protein ARHGAP21, we hypothesize that PTEN controls Cdc42-dependent morphogenic processes through a β-Arrestin1-ARHGAP21 complex. Here we show that PTEN knockdown (KD) impairs β-Arrestin1 membrane localization, β-Arrestin1-ARHGAP21 interactions, Cdc42 activation, mitotic spindle orientation and 3D glandular morphogenesis. Effects of PTEN-deficiency were phenocopied by β-Arrestin1 KD or inhibition of β-Arrestin1-ARHGAP21 interactions. Conversely, silencing of ARHGAP21 enhanced Cdc42 activation and rescued aberrant morphogenic processes of PTEN-deficient cultures. Expression of the PTEN C2 domain mimicked effects of full-length PTEN but a membrane-binding defective mutant of the C2 domain abrogated these properties. Our results show that PTEN controls multicellular assembly through a membrane-associated regulatory protein complex composed of β-Arrestin1, ARHGAP21 and Cdc42