Zamke za nositelje naboja u stupnjevanim InGaAS fotodiodama s velikim sadržajem indija

Carrier traps in In0.82Ga0.18As, introduced during manufacturing of photodiodes by vapour phase epitaxy (VPE), have been studied by electrical measurements. Two groups of localized energy levels associated with traps were found in photodiodes annealed at higher temperature after fabrication: the first, at Ec- 0.14 eV, and the second located deeper, close to the middle of the energy gap. Electrically activated dislocations by association with some impurities are responsible for the occurrence of the deeper levels.Električnim mjerenjima istražena su svojstva zamki za nositelje naboja koje nastaju pri izradi fotodioda iz In0.82Ga0.18As metodom epitaksijalnog rasta iz parne faze (VPE). U fotodiodama, koje su naknadno napuštane nakon izrade na povišenoj temperaturi, zapažene su dvije skupine lokaliziranih nivoa zamki: jedan plići na Ec − 0, 14 eV i druge dublje nešto ispod sredine zabranjenog energijskog pojasa. Ustanovljeno je da su električki aktivirane dislokacije primjesama odgovorne za pojavu dubljih nivoa

Association of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes

Background: Albuminuria has been classically considered a marker of kidney damage progression in diabetic patients and it is routinely assessed to monitor kidney function. However, the role of a mild GFR reduction on the development of stage 653 CKD has been less explored in type 1 diabetes mellitus (T1DM) patients. Aim of the present study was to evaluate the prognostic role of kidney disease measures, namely albuminuria and reduced GFR, on the development of stage 653 CKD in a large cohort of patients affected by T1DM. Methods: A total of 4284 patients affected by T1DM followed-up at 76 diabetes centers participating to the Italian Association of Clinical Diabetologists (Associazione Medici Diabetologi, AMD) initiative constitutes the study population. Urinary albumin excretion (ACR) and estimated GFR (eGFR) were retrieved and analyzed. The incidence of stage 653 CKD (eGFR < 60 mL/min/1.73 m2) or eGFR reduction > 30% from baseline was evaluated. Results: The mean estimated GFR was 98 \ub1 17 mL/min/1.73m2 and the proportion of patients with albuminuria was 15.3% (n = 654) at baseline. About 8% (n = 337) of patients developed one of the two renal endpoints during the 4-year follow-up period. Age, albuminuria (micro or macro) and baseline eGFR < 90 ml/min/m2 were independent risk factors for stage 653 CKD and renal function worsening. When compared to patients with eGFR > 90 ml/min/1.73m2 and normoalbuminuria, those with albuminuria at baseline had a 1.69 greater risk of reaching stage 3 CKD, while patients with mild eGFR reduction (i.e. eGFR between 90 and 60 mL/min/1.73 m2) show a 3.81 greater risk that rose to 8.24 for those patients with albuminuria and mild eGFR reduction at baseline. Conclusions: Albuminuria and eGFR reduction represent independent risk factors for incident stage 653 CKD in T1DM patients. The simultaneous occurrence of reduced eGFR and albuminuria have a synergistic effect on renal function worsening

A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

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