Використання поліфенолкарбонового комплексу з антарктичних чорних дріжджів Nadsoniella nigra в раціон птиці та їх вплив на інкубаційні якос-ті яєць перепілок несучок

The results of research on the influence of the polyphenol carbon complex from the Antarctic black yeast Nadsoniella nigra, which is additionally introduced into compound feed, are presented on the hatching qualities of quail eggs. Experimental studies were conducted in the conditions of the problematic research laboratory of feed additives of the National University of Bioresources and Nature Management of Ukraine. The material for the scientific and economic experiment was adult quail of the Pharaoh breed. Experiments were conducted using the group method. Accordingly, 192 heads of quails were selected for the experiment at 42 days, from which four groups were formed according to the principle of analogs - a control group and three experimental ones, 48 heads in each with four replications). When selecting analogs, the sex, age, and body weight of the bird were taken into account. The main period lasting 210 days, was divided into seven sub-periods, each of which lasted 30 days. The composition of the compound feed for the quails of the control and experimental groups and the set and number of ingredients in it were identical. The chemical composition of the combined feed used for feeding quails was the same and differed only in the content of PFC. During the experiment, the preservation of livestock and productivity were recorded, and feed conversion was also calculated. It was experimentally established that adding 0.1, 0.5, and 1.0 mg/kg polyphenol-carbon complex from the Antarctic black yeast Nadsoniella nigra to compound feed positively affects the hatching properties of eggs and, at the same time, reduces the percentage of hatching waste. At the same time, in the birds of the 3rd experimental group, which were fed 0.5 mg/kg of PFC as part of the compound feed, respectively, the percentage of fertilization was 2.2%; hatchability of eggs by 3.8%; and the yield of young by 5%, compared to birds that were not given PFC compound feed.Наведено результати досліджень з установлення впливу поліфенолкарбонового комплексу з антарктичних чорних дріжджів Nadsoniella nigra, який додатково вводять у комбікорми, на інкубаційні якості яєць перепелів. Експериментальні дослідження проводилися в умовах проблемної науково-дослідної лабораторії кормових добавок Національного університету біоресурсів і природокористування України. Матеріалом для науково-господарського досліду були дорослі перепели породи фараон. Досліди проводили за методом груп. Відповідно до цього для досліду у 42-добовому віці було відібрано 192 голови перепелів, з яких за принципом аналогів сформовано 4 групи – контрольну і три дослідні, по 48 голів у кожній з чотирма реплікаціями). При підборі аналогів враховували стать, вік і масу тіла птиці. Основний період тривалістю 210 діб було поділено на 7 підперіодів, кожен із яких тривав 30 діб. Склад комбікорму для перепелів контрольної та дослідних груп, набір і кількість інгредієнтів у ньому були ідентичними. Хімічний склад комбікорму, який використовували для годівлі перепелів, був однаковим і різнився лише за вмістом ПФК. Упродовж досліду проводився облік збереженості поголів’я, продуктивності, а також розраховували конверсію корму. Експериментально встановлено, що додавання до комбікорму 0,1, 0,5 та 1,0 мг/кг поліфенолкарбонового комплексу з антарктичних чорних дріжджів Nadsoniella nigra позитивно впливає на інкубаційні властивості яєць і при цьому знижує відсоток відходів інкубації. Водночас у птиці 3-ї дослідної групи, якій у складі комбікорму згодовували 0,5 мг/кг ПФК, відповідно за відсотком запліднення на 2,2 %; виводимістю яєць на 3,8 %; та виходом молодняку на 5 %, порівняно з птицею, якій не вводили до складу комбікорму ПФК

Biodiversity surveys of grassland and coastal habitats in 2021 as a documentation of pre-war status in southern Ukraine

Background This paper presents two sampling-event datasets with occurrences of vascular plants, bryophytes and lichens collected in May-June 2021 in southern Ukraine. We aimed to collect high-quality biodiversity data in an understudied region and contribute it to international databases and networks. The study was carried out during the 15th Eurasian Dry Grassland Group (EDGG) Field Workshop in southern Ukraine and the Dark Diversity Network (DarkDivNet) sampling in the Kamianska Sich National Nature Park. By chance, these datasets were collected shortly before the major escalation of the Russian invasion in Ukraine. Surveyed areas in Kherson and Mykolaiv Regions, including established monitoring plots, were severely affected by military actions in 2022. Therefore, collected data are of significant value in the context of biodiversity documentation. The knowledge about the biodiversity of this area will help to assess the environmental impact of the war and plan restoration of the damaged or destroyed habitats. The first preliminary analysis of collected data demonstrates the biodiversity richness and conservation value of studied grassland habitats. New information We provide sampling-event datasets with 7467 occurrences, which represent 708 taxa (vascular plants, bryophytes and lichens) collected in 275 vegetation relevés. Amongst them, vascular plants are represented by 6665 occurrences (610 taxa), lichens - 420 (46) and bryophytes - 381 (51). Several new species were reported for the first time at the national or regional level. In particular, one vascular plant species (Torilis pseudonodosa) and two lichen species (Cladonia conista, Endocarpon loscosii) were new to Ukraine. One vascular plant (Stipa tirsa), two species of bryophytes (Rhynchostegium megapolitanum, Ptychostomum torquescens) and three species of lichens (Cladonia cervicornis, C. symphycarpa, Involucropyrenium breussi) were recorded for the first time for the Kherson Region. Additionally, these datasets contain occurrences of taxa with narrow distribution, specialists of rare habitat types and, therefore, represented by a low number of occurrences in relevant biodiversity databases and particularly in GBIF. This publication highlights the diversity of natural vegetation and its flora in southern Ukraine and raises conservation concerns

Making tourist guidance systems more intelligent, adaptive and personalised using crowd sourced movement data

Ambient intelligence (AmI) provides adaptive, personalized, intelligent, ubiquitous and interactive services to wide range of users. AmI can have a variety of applications, including smart shops, health care, smart home, assisted living, and location-based services. Tourist guidance is one of the applications where AmI can have a great contribution to the quality of the service, as the tourists, who may not be very familiar with the visiting site, need a location-aware, ubiquitous, personalised and informative service. Such services should be able to understand the preferences of the users without requiring the users to specify them, predict their interests, and provide relevant and tailored services in the most appropriate way, including audio, visual, and haptic. This paper shows the use of crowd sourced trajectory data in the detection of points of interests and providing ambient tourist guidance based on the patterns recognised over such data

Beliefs and preferences regarding biological treatments for severe asthma

Background: Severe asthma is a serious condition with a significant burden on patients' morbidity, mortality, and quality of life. Some biological therapies targeting the IgE and interleukin-5 (IL5) mediated pathways are now available. Due to the lack of direct comparison studies, the choice of which medication to use varies. We aimed to explore the beliefs and practices in the use of biological therapies in severe asthma, hypothesizing that differences will occur depending on the prescribers’ specialty and experience. Methods: We conducted an online survey composed of 35 questions in English. The survey was circulated via the INterasma Scientific Network (INESNET) platform as well as through social media. Responses from allergists and pulmonologists, both those with experience of prescribing omalizumab with (OMA/IL5) and without (OMA) experience with anti-IL5 drugs, were compared. Results: Two hundred eighty-five (285) valid questionnaires from 37 countries were analyzed. Seventy-on percent (71%) of respondents prescribed biologics instead of oral glucocorticoids and believed that their side effects are inferior to those of Prednisone 5 mg daily. Agreement with ATS/ERS guidelines for identifying severe asthma patients was less than 50%. Specifically, significant differences were found comparing responses between allergists and pulmonologists (Chi-square test, p < 0.05) and between OMA/IL5 and OMA groups (p < 0.05). Conclusions: Uncertainties and inconsistencies regarding the use of biological medications have been shown. The accuracy of prescribers to correctly identify asthma severity, according to guidelines criteria, is quite poor. Although a substantial majority of prescribers believe that biological drugs are safer than low dose long-term treatment with oral steroids, and that they must be used instead of oral steroids, every effort should be made to further increase awareness. Efficacy as disease modifiers, biomarkers for selecting responsive patients, timing for outcomes evaluation, and checks need to be addressed by further research. Practices and beliefs regarding the use of asthma biologics differ between the prescriber's specialty and experience; however, the latter seems more significant in determining beliefs and behavior. Tailored educational measures are needed to ensure research results are better integrated in daily practice

7th Drug hypersensitivity meeting: part two

No abstract availabl

Toward personalization of asthma treatment according to trigger factors

© 2020 The Authors Asthma is a severe and chronic disabling disease affecting more than 300 million people worldwide. Although in the past few drugs for the treatment of asthma were available, new treatment options are currently emerging, which appear to be highly effective in certain subgroups of patients. Accordingly, there is a need for biomarkers that allow selection of patients for refined and personalized treatment strategies. Recently, serological chip tests based on microarrayed allergen molecules and peptides derived from the most common rhinovirus strains have been developed, which may discriminate 2 of the most common forms of asthma, that is, allergen- and virus-triggered asthma. In this perspective, we argue that classification of patients with asthma according to these common trigger factors may open new possibilities for personalized management of asthma