Performance investigation of ANFIS and PSO DFFP based boost converter with NICI using solar panel

The modeling and development of the boost DC to DC converter with Partial Swarm Optimization with Distinctive Feed Forward Propagation (PSO-DFFP) controller for hybrid power systems including solar panels. The static and dynamic investigation of the developed PSO DEEP controller is presented. The PSO-DFFP controller has been designed to improve the operating efficiency and reduces the input converter current ripple. The PSO DFFP controller is developed and performance is compared with ANFIS and FLC. The developed system reduces the switching losses and voltage drops in switching modes. The designed system is demonstrated and developed with 200W, 100kHz model. The investigation results is exposed that the developed PSO DEEP system is an acceptable for SOLAR applications

A Mathematical Model for Micropolar Fluid Flow Through an Artery with the effect of Stenosis and Post Stenotic Dilatation

The effects of both stenosis and post stenotic dilatation have been studied on steady flow of micropolar fluid through an artery. Assuming the stenosis to be mild, the equations governing the flow of the proposed model are solved. Closed form expressions for the flow characteristics such as velocity, pressure drop, and volumetric flow rate, resistance to the flow and wall shear stress are derived. The effects of various parameters on resistance to the flow and wall shear stress have been analyzed through the graphs. It is found that the resistance to the flow increases with the height and length of the stenosis, but the resistance to the flow decreases with stenotic dilatation. With the increase of the coupling number the resistance to the flow increases. However, the effect of coupling number is not very significant. The resistance to the flow decreases with the micropolar fluid parameter. The wall shear stress increases with coupling number and stenosis height, but it decreases with micropolar fluid parameter and stenotic dilatation

Influence of LD slag on iron ore sinter properties and productivity

Large amounts of slags from steel plants are produced through basic oxygen furnace and LD furnace. The main purpose of LD process is to convert the molten pig iron and steel scraps into high quality steel. In India, the generation of steel melting slag is over 4 to 4.5 Mt per annum. The amount of steel slags from different steel industries are 150–200 kg/t of steel produced. Disposal of large quantities of slag becomes a big environmental concern. JSW Steel Limited is a 7.0 Mtpa integrated steel plant and produces 3200 tons of total steel making slag per day and in that LD slag is 2000 to 2500 t/day. This LD slag consists of 45.75% CaO, 22.0 % Fe and 8.22% MgO. Thus, recycling of LD slag through the sintering process recovers lime, iron and magnesia and thereby saving of flux material and iron ore. Due to high content of CaO one can replace LD slag by limestone in sintering process. Detail investigation was carried out through lab scale studies for estimating the maximum permissible limits of usage of LD slag in sinter making and to know the influence of LD slag addition on sinter productivity and properties. Experiments were conducted using the LD slag in sinter making from 0 to 60kg/t of sinter. FeO content of the sinter decreased, sinter productivity increased with increase in LD slag addition. Decrease in FeO content is due to decrease in sinter bed temperature and increase in productivity is due to decrease in LOI content of the sinter mix and absence of weight loss due to calcination process. The sinter strength and RDI of the sinter deteriorated due to non availability of free CaO in LD slag and this reduces the formation of calcium ferrites phase and more Fe2O3 remains as free phase due to less reaction with CaO. From the test results it was found that 30 to 35 kg LD slag can be used per ton of sinter to get desired properties of the sinter

Aspects of the Antiandrogenic/Antifertility Property of Azadirachtin-A from Azadirachta indica Leaves in Male Albino Rats: Effect on the Biochemical and Cauda EpididymalSperm Parameters

Technical azadirachtin, a major component of A. indica leaves, has low acute/subchronic toxicity and non-mutagenic/teratogenic in mammalian species along with minimal disruption to the ecosystem. The aim of the present study is to examine the dose dependent effect of azadirachtin-A on biochemical, sperm functional parameters and fertility performance in treated groups. Wistar strain male albino rats were administered subcutaneously with graded concentrations of azadirachtin-A (0.5, 1.0 and 1.5 mg in suspension of 50% DMSO, respectively / kg body weight) followed by maintaining suitable controls for 24 days. Five animals from each group were used for fertility test. 24 hrs after the last dose, the control and treated animals were sacrificed; reproductive organs were then used for biochemical analysis and cauda epididymal plasma for sperm analysis. No significant differences in their body weight were observed. However, at high dose level of 1.5 mg/kg body weight, there was a general decrease in reproductive organs weights, altering in biochemical parameters and reduction in the sperm functional parameters with increased abnormal sperms. Furthermore, fertility performance test showed 30% even at high dose of azadirachtin-A treated for 24 days. In this study such high dose effects may have resulted from the deficiency in the level of circulating androgen, probably due to androgen deficiency consequent to the anti-androgenic property of azadirachtin-A and using this compound, in effective dose manner, may be a potential candidate as a contraceptive agent for the induction of infertility in humans by means of phytochemical approach

H. influenzae potentiates airway epithelial cell responses to rhinovirus by increasing ICAM‐1 and TLR3 expression

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/154674/1/fsb2fj065806fje.pd

Study of Sterility Mosaic Disease Resistance on Immortal Population in Pigeonpea

The cultivated pigeon pea (Cajanus cajan) is one of the most important source of protein for worlds marginal and vegetarian population. Sterility mosaic disease (SMD) also known as “green plague of pigeonpea” is one of the severe threats in pigeon pea production causing severe yield loss. Keeping this in view, identification of SMD resistant cultivars with better understanding of inheritance of disease were key consideration for the present study. RILs were screened for SMD resistance with leaf stapling technique at Green house, IBT, PJTSAU during Kharif 2012 and 2013. RILs showed digenic ratio (9S:7R) for SMD resistance, indicating complementary gene action which showed dominance of susceptibility over resistant and based on the per cent disease incidence, the RILs could be broadly classified as resistant (PDI 20%).The SMD incidence among the 188 RILs ranged from 0 to 100% whereas, the susceptible parent (ICP 8863) showed mean value of 79.17% and resistant parent (ICPL 20097) showed it as 0%. Out of total 188 RILs screened, 90 RILs showed resistant reaction to SMD infection while 98 RILs were susceptible. 33 RILs were identified as resistant lines which consistently showed 0% PDI during screening for both the years

A Monoclonal Antibody Against V 3 Integrin Inhibits Development of Atherosclerotic Lesions in Diabetic Pigs

Atherosclerotic lesions develop and progress more rapidly in diabetic patients than in nondiabetic individuals. This may be caused by accelerated lesion formation in the high-glucose environment of diabetes. Smooth muscle cells (SMCs) cultured in high glucose are more responsive to growth factors such as insulin-like growth factor–1 (IGF-1). This enhanced response to IGF-1 is due in part to increased activation of the αVβ3 integrin. We tested whether αVβ3 integrin activation was increased in diabetic animals and whether an antibody to β3 would inhibit IGF-1 action and development of atherosclerosis. Eight male pigs were made diabetic with streptozotocin and fed a high-fat diet. A F(ab)2 antibody fragment directed at β3 was infused into one femoral artery, whereas the other artery received control F(ab)2 for 3.5 months. There was a 65 ± 8% reduction in atherosclerotic lesion area in the arteries treated with F(ab)2 antibody to β3. Phosphorylation of β3 was reduced by 75 ± 18% in vessels treated with the antibody. Shc and mitogen-activated protein kinase phosphorylation, which are required for IGF-1–stimulated SMC proliferation, were also significantly reduced. We conclude that activation of IGF-1 receptor and αVβ3-linked signaling pathways accelerates atherosclerosis in diabetes and that administration of an antibody to β3 to diabetic pigs inhibits αVβ3 activation, IGF-1–stimulated signaling, and atherosclerotic lesion development. This approach offers a potential therapeutic approach to the treatment of this disorder

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

Although theMYConcogene has been implicated incancer, a systematic assessment of alterations ofMYC, related transcription factors, and co-regulatoryproteins, forming the proximal MYC network (PMN),across human cancers is lacking. Using computa-tional approaches, we define genomic and proteo-mic features associated with MYC and the PMNacross the 33 cancers of The Cancer Genome Atlas.Pan-cancer, 28% of all samples had at least one ofthe MYC paralogs amplified. In contrast, the MYCantagonists MGA and MNT were the most frequentlymutated or deleted members, proposing a roleas tumor suppressors.MYCalterations were mutu-ally exclusive withPIK3CA,PTEN,APC,orBRAFalterations, suggesting that MYC is a distinct onco-genic driver. Expression analysis revealed MYC-associated pathways in tumor subtypes, such asimmune response and growth factor signaling; chro-matin, translation, and DNA replication/repair wereconserved pan-cancer. This analysis reveals insightsinto MYC biology and is a reference for biomarkersand therapeutics for cancers with alterations ofMYC or the PMN