The role of upper tropospheric jet streaks and lee-side cyclogenesis in the development of low level jets in the great plains

A review of 15 cases of low level jets (LLJ) which developed in the Great Plains is presented. For 12 out of the 15 cases, a systematic upper level flow pattern was isolated which includes the existence of a trough over the southwest United States and the propagation of upper level jet streaks from the Rocky Mountains toward the Great Plains. This flow pattern is responsible for lee side cyclogenesis or lee side troughing that produces the pressure gradients needed for the development of the LLJ. For the other three cases, a blocking ridge existed over the Great Plains and the upper level flow is relatively weak. It is during these situations that the classic, diurnal oscillating LLJ was observed. A more detailed review of four cases indicates that the subsynoptic scale adjustments associated with the upper level jet streak's forcing of lee side cyclogenesis could be an important factor in the development of LLJ's in the Great Plains

VAS Demonstration Sounding Workshop: The Proceedings of a satellite sounding workshop

Retrieval techniques that yield satellite derived temperature and moisture profiles are considered, with emphasis on TIROS-N and VISSR atmospheric sounder measurements. Topics covered include operational sounding, colocation concepts, correcting cloud errors, and the First GARP Global Experiment

A survey of major east coast snowstorms, 1960-1983. Part 2: Case studies of eighteen storms

Snowfall, surface and upper air charts, and available satellite images are presented for eighteen major East Coast snowstorms that occurred between 1960 and 1983. The charts and descriptions of key fields are provided so that students, weather forecasters, and researchers alike can visualize how a large sample of major winter cyclones form and intensify. Although there are noted similarities in certain aspects of the surface and upper tropospheric development of the storms, significant case-to-case variability precludes the ability to effectively composite these weather systems

Low-level water vapor fields from the VISSR atmospheric sounder (VAS) split window channels at 11 and 12 microns

A series of high-resolution water vapor fields were derived from the 11 and 12 micron channels of the VISSR Atmospheric Sounder (VAS) on GOES-5. The low-level tropospheric moisture content was separated from the surface and atmospheric radiances by using the differential adsorption across the 'split window' along with the average air temperature from imbedded radiosondes. Fields of precipitable water are presented in a time sequence of five false color images taken over the United States at 3-hour intervals. Vivid subsynoptic and mesoscale patterns evolve at 15 km horizontal resolution over the 12-hour observing period. Convective cloud formations develop from several areas of enhanced low-level water vapor, especially where the vertical water vapor gradient relatively strong. Independent verification at radiosonde sites indicates fairly good absolute accuracy, and the spatial and temporal continuity of the water vapor features indicates very good relative accuracy. Residual errors are dominated by radiometer noise and unresolved clouds

VAS demonstration: (VISSR Atmospheric Sounder) description

The VAS Demonstration (VISSR Atmospheric Sounder) is a project designed to evaluate the VAS instrument as a remote sensor of the Earth's atmosphere and surface. This report describes the instrument and ground processing system, the instrument performance, the valiation as a temperature and moisture profiler compared with ground truth and other satellites, and assesses its performance as a valuable meteorological tool. The report also addresses the availability of data for scientific research

A description of the NSSL cases used for a simulated VAS retrieval study

A documentation of eight National Severe Storm Laboratory severe storm cases, which serve as a basis for a simulated VISSR Atmospheric Sounder retrieval study, is presented in this paper. Six of the selected cases provide a control data set to complete the statistical information needed for retrieval techniques based upon the use of regression matrices. The other two cases are to be used in the actual retrieval experiments. The selection was based upon the presence of moisture gradients in the analysis region, the availability of satellite images at the selected time periods, and the extent of cloud cover within the observing network

The President's Day cyclone 17-19 February 1979: An analysis of jet streak interactions prior to cyclogenesis

The President's Day cyclone, produced record breaking snowfall along the East Coast of the United States in February 1979. Conventional radiosonde data, SMS GOES infrared imagery and LFM 2 model diagnostics were used to analyze the interaction of upper and lower tropospheric jet streaks prior to cyclogenesis. The analysis reveals that a series of complex scale interactive processes is responsible for the development of the intense cyclone. The evolution of the subsynoptic scale mass and momentum fields prior to and during the period of rapid development of the President's Day cyclone utilizing conventional data and SMS GOES imagery is documented. The interaction between upper and lower tropospheric jet streaks which occurred prior to the onset of cyclogenesis is discussed as well as the possible effects of terrain modified airflow within the precyclogenesis environment. Possible deficiencies in the LFM-2 initial wind fields that could have been responsible, in part, for the poor numerical forecast are examined

Assessment of VAS soundings in the analysis of a preconvective environment

Retrievals from the VISSR Atmospheric Sounder (VAS) are combined with conventional data to assess the impact of geosynchronous satellite soundings upon the analysis of a preconvective environment. VAS retrievals of temperature, dewpoint, equivalent potential temperature, precipitable water, and lifted index are derived with 60 km resolution at 3 hour intervals. When VAS fields are combined with analyses from conventional data sources, mesoscale regions with convective instability are more clearly delineated prior to the rapid development of the thunderstorms. The retrievals differentiate isolated areas in which air extends throughout the lower troposphere from those regions where moisture is confined to a thin layer near the Earth's surface. The analyses of the VAS retrievals identify significant spatial gradients and temporal changes in the thermal and moisture fields, especially in the regions between radiosonde observations

Recent examples of mesoscale numerical forecasts of severe weather events along the east coast

Mesoscale numerical forecasts utilizing the Mesoscale Atmospheric Simulation System (MASS) are documented for two East Coast severe weather events. The two events are the thunderstorm and heavy snow bursts in the Washington, D.C. - Baltimore, MD region on 8 March 1984 and the devastating tornado outbreak across North and South Carolina on 28 March 1984. The forecasts are presented to demonstrate the ability of the model to simulate dynamical interactions and diabatic processes and to note some of the problems encountered when using mesoscale models for day-to-day forecasting

HOST GENETIC INFLUENCE ON HIV AND HCV INFECTIONS

In patients with chronic hepatitis C, the hepatitis C virus (HCV) RNA level is an important predictor of treatment response. To explore the relationship of HCV RNA with viral and demographic factors, as well as IL28B genotype, we examined viral levels in an ethnically diverse group of injection drug users (IDUs). Between 1998 and 2000, the Urban Health Study (UHS) recruited IDUs from street settings in San Francisco Bay area neighborhoods. Participants who were positive by HCV EIA were tested for HCV viremia by a bDNA assay. HCV genotype was determined by sequencing the HCV NS5B region. For a subset of participants, IL28B rs12979860 genotype was determined by Taqman. Among 1701 participants with HCV viremia, median age was 46 years and median duration of injection drug use was 26 years; 56.0% were African American and 34.0% were of European ancestry (non-Hispanic). HIV-1 prevalence was 13.9%. The overall median HCV RNA level was 6.45 log10 copies/ml. In unadjusted analyses, higher levels were found with older age, male gender, African American ancestry, HBV infection, HIV-1 infection and IL28B rs12979860-CC genotype; compared to participants infected with HCV genotype 1, HCV RNA was lower in participants with genotype 3 or genotype 4. In an adjusted analysis, age, gender, racial ancestry, HIV-1 infection, HCV genotype and IL28B rs12979860 genotype were all independently associated with HCV RNA. The level of HCV viremia is influenced by a large number of demographic, viral and human genetic factors. HIV The clinical course of HIV-1 infection is highly variable among individuals, at least in part as a result of genetic polymorphisms in the host. Toll-like receptors (TLR) play a crucial role in the host\u2019s innate immunity and may influence HIV-1 disease progression. The transcription factor IRF-5 is an important player in the TLR-MyD88 signaling cascade. We investigated the impact of two SNPs in TLR9 gene, rs352139 and rs352140, and two SNPs in IRF5 gene, rs10954213 and rs11770589, on CD4 count, HIV viral load, and clinical progression in a cohort of HIV-infected patients. Two SNPs in TLR9 and IRF5 are in linkage disequilibrium and rs352140GA TLR9 was associated with the rapid progressors phenotype: for rs352140 GG+GA versus AA, P = 0.025, OR= 0.5479, confidence interval (CI) 0.31-0.97. No other association was found between TLR9 and IRF5 SNPs and viral load, CD4 count or other clinical data. Rapid progression of HIV-1 infection was associated with TLR9 polymorphisms. Because of its potential implications for intervention strategies and vaccine developments, additional epidemiological and experimental studies are needed to confirm this association