941 research outputs found
Impacts of studying in a regional medical campus on practice location
Background: New Brunswick, a bilingual Canadian province without a medical school, negotiated an agreement in 1967 in which places were reserved for francophone medical students in the province of Quebec. In 2006, the Centre de Formation MĂ©dicale du Nouveau-Brunswick (CFMNB), a regional medical campus (RMC) of UniversitĂ© de Sherbrooke for its provincial francophone medical students, was established to increase the likelihood of graduates setting up practice in the region. Practice locations of the initial 5 cohorts of CFMNB were analysed to compare data with francophone students trained in Quebec.Methods: Practice locations were determined through Scottâs Medical Database and provincial public registries. Chi-square and relative risk probability were used to examine the relationship between training location and practice location.Results: Doctors trained at CFMNB were 1.4 times more likely to be practicing in Atlantic Canada compared to those trained at UniversitĂ© de Sherbrooke (main campus) before 2006. Those trained at CFMNB were 1.3 times more likely to go on to practice in the region compared to those trained at UniversitĂ© Laval or UniversitĂ© de MontrĂ©al. Conclusion: This study supports the hypothesis that individuals completing a medical program in a Francophone RMC in New Brunswick increases the likelihood of them later practicing in the province or in the wider Atlantic Canada region._______Contexte: Le Nouveau-Brunswick, une province canadienne bilingue ne possĂ©dant pas de FacultĂ© de mĂ©decine, a nĂ©gociĂ© en 1967 une entente avec le QuĂ©bec afin de rĂ©server des places pour ses Ă©tudiants francophones souhaitant Ă©tudier la mĂ©decine. En 2006, le Centre de formation mĂ©dicale du Nouveau-Brunswick (CFMNB), un campus mĂ©dical rĂ©gional (CMR) de lâUniversitĂ© de Sherbrooke, a Ă©tĂ© crĂ©Ă© afin de permettre aux NĂ©o-Brunswickois dâĂ©tudier la mĂ©decine en français dans leur province. Lâun des objectifs principaux du CFMNB Ă©tait dâaugmenter les probabilitĂ©s que les diplĂŽmĂ©s en mĂ©decine sâĂ©tablissent dans la rĂ©gion. Les lieux de pratique des mĂ©decins issus des 5 premiĂšres cohortes du CFMNB ont Ă©tĂ© analysĂ©s afin de les comparer avec ceux des mĂ©decins francophones dâorigine nĂ©o-brunswickoise formĂ©s au QuĂ©bec.MĂ©thodes: Les lieux de pratique ont Ă©tĂ© dĂ©terminĂ©s via le rĂ©pertoire des mĂ©decins Scottâs et les registres publics provinciaux. Des tests de Chi carrĂ© et des analyses de risque ont Ă©tĂ© conduits afin dâĂ©tudier la relation entre le lieu de formation et le lieu de pratique.RĂ©sultats: Les mĂ©decins formĂ©s au CFMNB Ă©taient 1.4 fois plus enclins Ă travailler au Canada atlantique comparativement Ă ceux formĂ©s au campus principal de lâUniversitĂ© de Sherbrooke avant 2006. Les mĂ©decins formĂ©s au CFMNB Ă©taient Ă©galement 1.3 fois plus enclins Ă travailler dans la rĂ©gion que ceux formĂ©s Ă lâUniversitĂ© Laval ou Ă lâUniversitĂ© de MontrĂ©al.Conclusion: Cette Ă©tude supporte lâhypothĂšse selon laquelle le fait de complĂ©ter un programme de mĂ©decine francophone dans un CMR francophone au Nouveau-Brunswick augmente les chances de pratiquer au Nouveau-Brunswick ou dans la grande rĂ©gion du Canada atlantique.
Les dĂ©cisions spontanĂ©es dâĂ©lĂšves de sixiĂšme annĂ©e dans le contexte dâun projet de dĂ©veloppement durable
Les individus influencent la qualitĂ© de lâenvironnement dans leurs rĂŽles de citoyens,
dâinvestisseurs et de membres dâorganisations effectuant des choix environnementaux. Or, la
prise de décision, en environnement et particuliÚrement chez les jeunes, est encore peu
comprise. La recherche présentée avait pour objectif de décrire le processus décisionnel
spontanĂ© dâĂ©lĂšves de 10-11 ans, dans le contexte dâun dĂ©veloppement rĂ©sidentiel viable. Les
chercheuses voulaient comprendre de quelle façon les élÚves représentaient spontanément leur
processus dĂ©cisionnel et les raisons qui motivaient leurs choix. Lâapproche pĂ©dagogique
choisie pour le projet en classe a été celle de la simulation globale. Les élÚves ont été
invités à jouer les rÎles des futurs citoyens du développement résidentiel et à prendre des
décisions concernant les aménagements à prévoir sur leur propriété. Les outils de collecte
de données ont été le journal réflexif des élÚves et le journal de la chercheuse. Dans les
résultats, on observe que les élÚves représentent leur processus décisionnel de façon variée
(textes, schĂ©mas, listes, tableaux, dessins et plans) et quâils ont recours Ă divers modes
décisionnels : la compilation des avantages semblables, le choix par élimination, la liste
de comparaison des avantages et inconvénients, le choix par compatibilité des options, le
choix basĂ© sur lâargumentation, celui basĂ© sur la description et le choix par visualisation
du rĂ©sultat anticipĂ©. La volontĂ© dâĂȘtre entourĂ© dâun environnement esthĂ©tiquement agrĂ©able
et aménagé selon ses préférences personnelles sont les principales sources de motivation des
Ă©lĂšves dans leurs choix dâamĂ©nagement.Individuals influence the quality of the environment through their roles as citizens,
investors, and members of organizations making choices that impact the environment. Yet,
decision making regarding the environment, especially among young people, is not well
understood. This study sought to describe the spontaneous decision-making process of 10-11
years old students, in the context of a sustainable residential neighborhood. The
researchers aimed to understand how the students would spontaneously represent their
decision-making process and the reasons that motivated their choices. Through their
participation in a global simulation, the students were given fictitious identity,
representing the future citizens of the residential neighborhood, and had to make decisions
concerning the landscaping of their properties. The studentsâ reflexive journals and the
researcherâs journal were the tools used to collect the data. In our results, we observed
that the students used a variety of representations of their decision process (texts,
schemata, lists, tables, drawings and plans) and a variety of decision modes : the
compilation of similar advantages, the choice by elimination, the list of comparison of
advantages and disadvantages, the choice based on compatibility of the options, the choice
based on argumentation, the choice base on description, and the choice by visualization of
the anticipated result. The studentsâ will of being surrounded by an environment that is
visually pleasant and corresponds to their personal preferences are the main motivations
behind their choices
Cocaine Intoxication and Thyroid Storm: Similarity in Presentation and Implications for Treatment
Introduction: Cocaine, a widely used sympathomimetic drug, causes thermoregulatory and cardiac manifestations that can mimic a life-threatening thyroid storm. Case: A man presented to the emergency department requesting only cocaine detoxification. He reported symptoms over the last few years including weight loss and diarrhea, which he attributed to ongoing cocaine use. On presentation he had an elevated temperature of 39.4°C and a HR up to 130 beats per minute. Examination revealed the presence of an enlarged, non-tender goiter with bilateral continuous bruits. He was found to have thyrotoxicosis by labs and was treated for a thyroid storm and cocaine intoxication concurrently. The patient was ultimately diagnosed with Graves disease and treated with Iodine-131 therapy. Conclusion: Cocaine use should be considered a possible trigger for thyroid storm. Recognition of thyroid storm is critical because of the necessity for targeted therapy and the significant mortality associated with the condition when untreated.\u2
Irdisches Himmelreich. Die 'StitshĂŒtte' (Ex 25â40*)als theologische Metapher
Die biblische ErzĂ€hlung von der Errichtung des Sinaiheiligtums, der sogenannten StitshĂŒtte, im Buch Exodus Kap 25â40 wird als âausgefĂŒhrte Metapherâ im Sinne Paul Ricoeurs sowie als âabsolute Metapherâ im Sinne Hans Blumenbergs gedeutet. Das heilige Zelt und seine sakrale Ausstattung, das die Israeliten auf Anweisung Gottes an Mose herzustellen haben, soll Gott als âWohnungâ bei den Israeliten dienen. Der Raum und die RĂ€ume des Heiligtums werden aus unterschiedlichen Perspektiven entwickelt. Der metaphorische Charakter der ErzĂ€hlung erweist sich dadurch, dass das âWohnen Gottesâ nur in Spannung zwischen göttlichem und menschlichem Bereich dargestellt werden kann. Der Raum des Heiligtums vereinigt gegensĂ€tzliche und zugleich komplementĂ€re Weisen der PrĂ€senz Gottes unter den Menschen.The biblical narrative of the creation of the Sinai sanctuary, called the tabernacle, in the book of Exodus chapters 25-40 is interpreted as âliving metaphorâ in the sense of Paul Ricoeur as well as âabsolute metaphorâ in the sense of Hans Blumenberg. The tabernacle and its sacred furniture have to be built by the Israelites on Godâs instruction. It serves God as âdwellingâ among the Israelites. The space and the rooms of the sanctuary are developed from different perspectives. The metaphorical character of the narrative is proved by the fact that the âdwelling of Godâ can only be represented in the tension between divine and human realms. The space of the sanctuary unites opposing yet complementary ways of Godâs presence among mankind
PMMA Third-Body Wear after Unicondylar Knee Arthroplasty Decuples the UHMWPE Wear Particle Generation In Vitro
Introduction. Overlooked polymethylmethacrylate after unicondylar knee arthroplasty can be a potential problem, since this might influence the generated wear particle size and morphology. The aim of this study was the analysis of polyethylene wear in a knee wear simulator for changes in size, morphology, and particle number after the addition of third-bodies. Material and Methods. Fixed bearing unicondylar knee prostheses (UKA) were tested in a knee simulator for 5.0 million cycles. Following bone particles were added for 1.5million cycles, followed by 1.5million cycles with PMMA particles. A particle analysis by scanning electron microscopy of the lubricant after the cycles was performed. Size and morphology of the generated wear were characterized. Further, the number of particles per 1 million cycles was calculated for each group. Results. The particles of all groups were similar in size and shape. The number of particles in the PMMA group showed 10-fold higher values than in the bone and control group (PMMA: 10.251 x 10(12); bone: 1.145x10(12); control: 1.804x10(12)). Conclusion. The addition of bone or PMMA particles in terms of a third-body wear results in no change of particle size and morphology. PMMA third-bodies generated tenfold elevated particle numbers. This could favor an early aseptic loosening
Histopathological Analysis of PEEK Wear Particle Effects on the Synovial Tissue of Patients
Introduction. Increasing interest developed in the use of carbon-fiber-reinforced-poly-ether-ether-ketones (CFR-PEEK) as an alternative bearing material in knee arthroplasty. The effects of CFR-PEEK wear in in vitro and animal studies are controversially discussed, as there are no data available concerning human tissue. The aim of this study was to analyze human tissue containing CFR-PEEK as well as UHMWPE wear debris. The authors hypothesized no difference between the used biomaterials. Methods and Materials. In 10 patients during knee revision surgery of a rotating-hinge-knee-implant-design, synovial tissue samples were achieved (tibial inserts: UHMWPE;bushings and flanges: CFR-PEEK). One additional patient received revision surgery without any PEEK components as a control. The tissue was paraffin-embedded, sliced into 2 mu m thick sections, and stained with hematoxylin and eosin in a standard process. A modified panoptical staining was also done. Results. A "wear-type" reaction was seen in the testing and the control group. In all samples, the UHMWPE particles were scattered in the tissue or incorporated in giant cells. CFR-PEEK particles were seen as conglomerates and only could be found next to vessels. CFR-PEEK particles showed no giant-cell reactions. In conclusion, the hypothesis has to be rejected. UHMWPE and PEEK showed a different scatter-behavior in human synovial tissue
Increase in the Tibial Slope Reduces Wear after Medial Unicompartmental Fixed-Bearing Arthroplasty of the Knee
Introduction. Unicompartmental arthroplasty of the knee in patients with isolated medial osteoarthritis gives good results, but survival is inferior to that of total knee prosthesis. Knees may fail because positioning of the prosthesis has been suboptimal. The aim of this study was to investigate the influence of the tibial slope on the rate of wear of amedial fixed-bearing unicompartmental knee arthroplasty. Materials and Methods. We simulated wear on a medial fixed-bearing unicompartmental knee prosthesis (Univation) in vitro with a customised, four-station, and servohydraulic knee wear simulator, which exactly reproduced the walking cycle (International Organisation for Standardisation (ISO) 14243-1: 2002(E)). The medial prostheses were inserted with 3 different posterior tibial slopes: 0 degrees, 4 degrees, and 8 degrees (n = 3 in each group). Results. The wear rate decreased significantly between 0 degrees and 4 degrees slope from 10.4 (SD 0.62) mg/million cycles to 3.22 (SD 1.71) mg/million cycles. Increasing the tibial slope to 8 degrees did not significantly change the wear rate. Discussion. As an increase in the tibial slope reduced the wear rate in a fixed-bearing prosthesis, a higher tibial slope should be recommended. However, other factors that are influenced by the tibial slope (e.g.,the tension of the ligament) must also be considered
Increase in the Tibial Slope Reduces Wear after Medial Unicompartmental Fixed-Bearing Arthroplasty of the Knee
Introduction. Unicompartmental arthroplasty of the knee in patients with isolated medial osteoarthritis gives good results, but survival is inferior to that of total knee prosthesis. Knees may fail because positioning of the prosthesis has been suboptimal. The aim of this study was to investigate the influence of the tibial slope on the rate of wear of amedial fixed-bearing unicompartmental knee arthroplasty. Materials and Methods. We simulated wear on a medial fixed-bearing unicompartmental knee prosthesis (Univation) in vitro with a customised, four-station, and servohydraulic knee wear simulator, which exactly reproduced the walking cycle (International Organisation for Standardisation (ISO) 14243-1: 2002(E)). The medial prostheses were inserted with 3 different posterior tibial slopes: 0 degrees, 4 degrees, and 8 degrees (n = 3 in each group). Results. The wear rate decreased significantly between 0 degrees and 4 degrees slope from 10.4 (SD 0.62) mg/million cycles to 3.22 (SD 1.71) mg/million cycles. Increasing the tibial slope to 8 degrees did not significantly change the wear rate. Discussion. As an increase in the tibial slope reduced the wear rate in a fixed-bearing prosthesis, a higher tibial slope should be recommended. However, other factors that are influenced by the tibial slope (e.g.,the tension of the ligament) must also be considered
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