A laser gyroscope system to detect the Gravito-Magnetic effect on Earth

Large scale square ring laser gyros with a length of four meters on each side are approaching a sensitivity of 1x10^-11 rad/s/sqrt(Hz). This is about the regime required to measure the gravitomagnetic effect (Lense Thirring) of the Earth. For an ensemble of linearly independent gyros each measurement signal depends upon the orientation of each single axis gyro with respect to the rotational axis of the Earth. Therefore at least 3 gyros are necessary to reconstruct the complete angular orientation of the apparatus. In general, the setup consists of several laser gyroscopes (we would prefer more than 3 for sufficient redundancy), rigidly referenced to each other. Adding more gyros for one plane of observation provides a cross-check against intra-system biases and furthermore has the advantage of improving the signal to noise ratio by the square root of the number of gyros. In this paper we analyze a system of two pairs of identical gyros (twins) with a slightly different orientation with respect to the Earth axis. The twin gyro configuration has several interesting properties. The relative angle can be controlled and provides a useful null measurement. A quadruple twin system could reach a 1% sensitivity after 3:2 years of data, provided each square ring has 6 m length on a side, the system is shot noise limited and there is no source for 1/f- noise.Comment: 9 pages, 6 figures. 2010 Honourable mention of the Gravity Research Foundation; to be published on J. Mod. Phys.

Magnons in real materials from density-functional theory

We present an implementation of the adiabatic spin-wave dynamics of Niu and Kleinman. This technique allows to decouple the spin and charge excitations of a many-electron system using a generalization of the adiabatic approximation. The only input for the spin-wave equations of motion are the energies and Berry curvatures of many-electron states describing frozen spin spirals. The latter are computed using a newly developed technique based on constrained density-functional theory, within the local spin density approximation and the pseudo-potential plane-wave method. Calculations for iron show an excellent agreement with experiments.Comment: 1 LaTeX file and 1 postscript figur

High-Accuracy Ring Laser Gyroscopes: Earth Rotation Rate and Relativistic Effects

The Gross Ring G is a square ring laser gyroscope, built as a monolithic Zerodur structure with 4 m length on all sides. It has demonstrated that a large ring laser provides a sensitivity high enough to measure the rotational rate of the Earth with a high precision of ∆ΩE < 10-8. It is possible to show that further improvement in accuracy could allow the observation of the metric frame dragging, produced by the Earth rotating mass (Lense-Thirring effect), as predicted by General Relativity. Furthermore, it can provide a local measurement of the Earth rotational rate with a sensitivity near to that provided by the international system IERS. The GINGER project is intending to take this level of sensitivity further and to improve the accuracy and the long-term stability. A monolithic structure similar to the G ring laser is not available for GINGER. Therefore the preliminary goal is the demonstration of the feasibility of a larger gyroscope structure, where the mechanical stability is obtained through an active control of the geometry. A prototype moderate size gyroscope (GP-2) has been set up in Pisa in order to test this active control of the ring geometry, while a second structure (GINGERino) has been installed inside the Gran Sasso underground laboratory in order to investigate the properties of a deep underground laboratory in view of an installation of a future GINGER apparatus. The preliminary data on these two latter instruments are presented

Intensified chemotherapy and simultaneous treatment with heparin in outpatients with pancreatic cancer - the CONKO 004 pilot trial

BACKGROUND: Advanced pancreatic cancer (APC), beside its high mortality, causes the highest rates of venous thromboembolic events (VTE). Enoxaparin, a low molecular weight heparin (LMWH), is effective in prevention and treatment of VTE. Some small studies indicated that this benefit might extend to patients with cancer and probably prolong survival due to independent mechanisms. We initiated this safety investigation to get feasibility information on intensified chemotherapy combined with LMWH in outpatients with APC treated in 1st line. METHODS: The trial was a prospective, open-label, single center investigation in outpatients with inoperable pancreatic cancer who were treated with intensified first-line chemotherapy along with concomitant application of subcutaneous LMWH. The combined chemotherapy consisted of gemcitabine 1 g/m2 (30 min), 5-FU 750 mg/m2 (24 h), folinic acid 200 mg/m2 (30 min), and Cisplatin 30 mg/m2 (90 min) on day 1 and 8; q3w for the first 12 weeks (GFFC) followed by gemcitabine alone in patients without cancer progression. The simultaneous application of prophylactic enoxaparin started on day 1 of chemotherapy with a fixed dose of 40 mg daily. Statistical analyses were performed using R 3.01 with software package CMPRSK and SPSS software v19.0. RESULTS: The investigation was stopped after recruitment of 19 patients. At this time 15 patients had completed the required 12 weeks of treatment. Based on 71 cycles of GFFC + enoxaparin (median 4/pt [range: 2-4]) and 108 cycles of single-agent gemcitabine + enoxaparin (median 4/pt [range: 0-18]) the cumulative frequency of NCI-CTC toxicities grade 3/4 was below 10%. One case (5%) of a symptomatic non-lethal thromboembolic event was observed while receiving LMWH treatment. No severe bleeding event as defined in the protocol has been observed. The median overall survival was 10.05 [95%CI: 8.67-18.14] months. CONCLUSIONS: The addition of enoxaparin to GFFC chemotherapy is feasible, safe and does not appear to affect the efficacy or the toxicity profile of the chemotherapy regimen in patients with advanced pancreatic adenocarcinoma. Based on these findings we have initiated the randomized CONKO-004 trial to examine whether enoxaparin reduces the incidence of thromboembolic events or increases overall outcome. Trial registration: Clinical Trials NCT01945879

Measuring Gravito-magnetic Effects by Multi Ring-Laser Gyroscope

We propose an under-ground experiment to detect the general relativistic effects due to the curvature of space-time around the Earth (de Sitter effect) and to rotation of the planet (dragging of the inertial frames or Lense-Thirring effect). It is based on the comparison between the IERS value of the Earth rotation vector and corresponding measurements obtained by a tri-axial laser detector of rotation. The proposed detector consists of six large ring-lasers arranged along three orthogonal axes. In about two years of data taking, the 1% sensitivity required for the measurement of the Lense-Thirring drag can be reached with square rings of 6 $m$ side, assuming a shot noise limited sensitivity ($20 prad/s/\sqrt{Hz}$). The multi-gyros system, composed of rings whose planes are perpendicular to one or the other of three orthogonal axes, can be built in several ways. Here, we consider cubic and octahedron structures. The symmetries of the proposed configurations provide mathematical relations that can be used to study the stability of the scale factors, the relative orientations or the ring-laser planes, very important to get rid of systematics in long-term measurements, which are required in order to determine the relativistic effects.Comment: 24 pages, 26 Postscript figure

Development of a selftriggered high counting rate ASIC for readout of 2D gas microstrip neutron detectors

In the frame of the DETNI project a 32-channel ASIC suitable for readout of a novel 2D thermal neutron detector based on a hybrid low-pressure Micro-Strip Gas Chamber with solid 157Gd converter has been developed. Each channel delivers position information, a fast time stamp of 2 ns resolution and the signal amplitude (called energy below). The time stamp is used for correlating the signals from X and Y strips while the amplitude is used for finding the center of gravity of a cluster of strips. The timing and energy information are stored in derandomizing buffers and read out via token ring architecture

Unsplittable coverings in the plane

A system of sets forms an {\em $m$-fold covering} of a set $X$ if every point of $X$ belongs to at least $m$ of its members. A $1$-fold covering is called a {\em covering}. The problem of splitting multiple coverings into several coverings was motivated by classical density estimates for {\em sphere packings} as well as by the {\em planar sensor cover problem}. It has been the prevailing conjecture for 35 years (settled in many special cases) that for every plane convex body $C$, there exists a constant $m=m(C)$ such that every $m$-fold covering of the plane with translates of $C$ splits into $2$ coverings. In the present paper, it is proved that this conjecture is false for the unit disk. The proof can be generalized to construct, for every $m$, an unsplittable $m$-fold covering of the plane with translates of any open convex body $C$ which has a smooth boundary with everywhere {\em positive curvature}. Somewhat surprisingly, {\em unbounded} open convex sets $C$ do not misbehave, they satisfy the conjecture: every $3$-fold covering of any region of the plane by translates of such a set $C$ splits into two coverings. To establish this result, we prove a general coloring theorem for hypergraphs of a special type: {\em shift-chains}. We also show that there is a constant $c>0$ such that, for any positive integer $m$, every $m$-fold covering of a region with unit disks splits into two coverings, provided that every point is covered by {\em at most} $c2^{m/2}$ sets

Measurement of the branching fractions of the B+ -> eta l(+)nu(l) and B+ -> eta ' l(+)nu(l) decays with signal-side only reconstruction in the full q(2) range

The branching fractions of the decays B+ -> eta l(+)nu(l) and B+ -> eta'l(+)nu(l) are measured, where l is either an electron or a muon, using a data sample of 711 fb(-1) containing 772 x 10(6)B (B) over bar pairs collected at the Upsilon(4S) resonance with the Belle detector at the KEKB asymmetric-energy e(+)e(-) collider. To reduce the dependence of the result on the form factor model, the measurement is performed over the entire q(2) range. The resulting branching fractions are B(B+ -> eta l(+)nu(l)) = (2.83 +/- 0.55((stat.)) +/- 0.34((syst.))) x 10(-5) and B(B+ -> eta'l(+)nu(l)) = (2.79 +/- 1.29((stat.)) +/- 0.30((syst.))) x 10(-5).journal articl

Long-term validation of Aeolus L2B wind products at Punta Arenas, Chile, and Leipzig, Germany

Ground-based observations of horizontal winds have been performed at Leipzig (51.35∘ N, 12.43∘ E), Germany, and at Punta Arenas (53.15∘ S, 70.91∘ W), Chile, in the framework of the German initiative EVAA (Experimental Validation and Assimilation of Aeolus observations) with respect to the validation of the Mie and Rayleigh wind products of Aeolus (L2B data). In Leipzig, at the Leibniz Institute for Tropospheric Research (TROPOS), radiosondes have been launched for the Aeolus overpasses on each Friday (ascending orbit) since the middle of May 2019. In Punta Arenas, scanning Doppler cloud radar observations have been performed in the framework of the DACAPO-PESO campaign (dacapo.tropos.de) for more than 3 years from the end of 2018 until the end of 2021 and could be used to validate Aeolus measurements on its ascending and descending orbits. We present two case studies and long‐term statistics of the horizontal winds derived with the ground-based reference instruments compared to Aeolus horizontal line-of-sight (HLOS) winds. The wind products of Aeolus considered are the Mie cloudy and Rayleigh clear products. It was found that the deviation of the Aeolus HLOS winds from the ground reference is usually of Gaussian shape, which allowed the use of the median bias and the scaled median absolute deviation (MAD) for the determination of the systematic and random errors of Aeolus wind products, respectively. The case study from August 2020 with impressive atmospheric conditions at Punta Arenas shows that Aeolus is able to capture strong wind speeds of up to more than 100 m s−1. The long-term validation was performed in Punta Arenas covering the period from December 2018 to November 2021 and in Leipzig from May 2019 until September 2022. This analysis showed that the systematic error of the Aeolus wind products could be significantly lowered during the mission lifetime with the changes introduced into the processing chain (different versions are called baselines). While in the early mission phase, systematic errors of more than 2 m s−1 (absolute values) were observed for both wind types (Mie and Rayleigh), these biases could be reduced with the algorithm improvements, such as the introduction of the correction for temperature fluctuations at the main telescope of Aeolus (M1 temperature correction) with Baseline 09. Hence, since Baseline 10, a significant improvement in the Aeolus data was found, leading to a low systematic error (close to 0 m s−1) and similar values for the midlatitudinal sites in both hemispheres. The random errors for both wind products were first decreasing with an increasing baseline but later increasing again due to performance losses of the Aeolus lidar instrument. Nevertheless, no significant increase in the systematic error in the Aeolus wind products was found. Thus, one can conclude that the uncertainty introduced by the reduced atmospheric return signal received by Aeolus mostly affects the random error. Even when considering all the challenges during the mission, we can confirm the general validity of Aeolus observations during its lifetime. Therefore, this space explorer mission could demonstrate that it is possible to perform active wind observations from space with the applied technique.</p

Moving from a Product-Based Economy to a Service-Based Economy for a More Sustainable Future

Traditionally, economic growth and prosperity have been linked with the availability, production and distribution of tangible goods as well as the ability of consumers to acquire such goods. Early evidence regarding this connection dates back to Adam Smith's Wealth of Nations (1776), in which any activity not resulting in the production of a tangible good is characterized as unproductive of any value." Since then, this coupling of economic value and material production has been prevalent in both developed and developing economies throughout the world. One unintended consequence of this coupling has been the exponential increase in the amount of solid waste being generated. The reason is that any production and consumption of material goods eventually generates the equivalent amount of (or even more) waste. Exacerbating this problem is the fact that, with today's manufacturing and supply chain management technologies, it has become cheaper to dispose and replace most products rather than to repair and reuse them. This has given rise to what some call a disposable society." To put things in perspective: In 2012 households in the U.K. generated approximately 22 thousand tons of waste, which amounted to 411 kg of waste generated per person (Department for Environment, Food & Rural Affairs, 2015). During the same time period, households in the U.S. generated 251 million tons of waste, which is equivalent to a person generating approximately 2 kg of waste every day (U.S. Environmental Protection Agency, 2012). Out of these 251 million tons of total waste generated, approximately 20% of the discarded items were categorized as durable goods. The disposal of durable goods is particularly worrisome because they are typically produced using material from non- renewable resources such as iron, minerals, and petroleum-based raw materials